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Biography
Dr Vanja Pekovic-Vaughan is a Senior Lecturer in Circadian & Musculoskeletal Physiology in the Department of Musculoskeletal and Ageing Sciences, Institute of Lifecourse and Medical Sciences (ILCAMs) at the University of Liverpool (UoL), where she was awarded a prestigious Welcome Trust Tenure-Track Fellowship. She is currently an Academic Lead for Research & Impact for her department and also serves on ILCAMs Research Strategy Group and Ethics Committees. She gained a BSc (Hon) in Human Genetics (Leeds University, UK) and a PhD in Molecular & Cellular Biology of Ageing (Durham University, UK). She undertook postdoctoral training in several of the UK’s leading laboratories (Universities of Newcastle, Durham, Manchester, KCL), investigating the role of cellular ageing and redox signalling in inherited human diseases and their temporal regulation by the cellular time-keeping mechanism, the circadian clock.
Dr Pekovic-Vaughan's laboratory is pursuing an interdisciplinary research spanning molecular biology, in vivo physiology, pharmacology and mathematical modelling to investigate the role of redox signalling and circadian rhythms in normal physiological processes from stem cell differentiation to cellular responses to stress as well as how their misalignment contributes to chronic age-related conditions (e.g. sarcopenia, lung fibrosis, chronic wounds, cardiac disease) and human inherited diseases (e.g. Collagen VI myopathies, Laminopathies, Peripheral neuropathies, Systemic Sclerosis, Marfan Syndrome and Fabry Disease). We are also actively studying the potential of utilizing chronotherapy in smarter drug repurposing (e.g. antiviral candidates in COVID-19, novel retinoic acid based candidates for neuromuscular ageing). The research programme is Dr Pekovic-Vaughan's group’s is funded through UKRI (MRC, BBSRC, EPSRC), Welcome Trust, RoseTreest Trust, Muscular Dystrophy (MD) UK, Dowager Eleanor Peel Trust, Age UK, Newton Fund, The Royal Society and CIMA.
Dr Pekovic-Vaughan serves as a UoL Network Coordinator on an ECMage Operational Group, a recently funded BBSRC/MRC interdisciplinary UK Ageing national network (UKAnet) for Ageing across LifeCourse (https://www.ukanet.org.uk/ec-mage). Currently, she serves as a Managing Scientific Editor for Elsevier publishers (Redox Biology) and as a Review Editor for IUBMB publishers (BioFactors). She is a UoL member of the MRC/Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA), collaboration between researchers and clinicians at the UK Universities of Liverpool, Sheffield and Newcastle (https://www.cimauk.org).
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