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Works (9)

VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response

Nature Communications
2024-04-04 | Journal article
DOI: 10.1038/s41467-024-47256-x
Contributors: Thomas Thisted; F. Donelson Smith; Arnab Mukherjee; Yuliya Kleschenko; Feng Feng; Zhi-Gang Jiang; Timothy Eitas; Kanam Malhotra; Zuzana Biesova; Adejumoke Onumajuru et al.
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Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics

Antibodies
2023-08-30 | Journal article
DOI: 10.3390/antib12030055
Contributors: F. Donelson Smith; Robert H. Pierce; Thomas Thisted; Edward H. van der Horst
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Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

2023-06-28 | Preprint
DOI: 10.1101/2023.06.28.546958
Contributors: Sophia M Lauer; Mitchell H Omar; Martin G Golkowski; Heidi L Kenerson; Bryan C Pascual; Katherine Forbush; F Donelson Smith; John Gordan; Shao-En Ong; Raymond S Yeung et al.
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A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface

Journal of Biological Chemistry
2020-07 | Journal article
DOI: 10.1074/jbc.RA120.013454
Contributors: Laura Gabrovsek; Kerrie B. Collins; Stacey Aggarwal; Lauren M. Saunders; Ho-Tak Lau; Danny Suh; Yasemin Sancak; Cole Trapnell; Shao-En Ong; F. Donelson Smith et al.
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Subcellular drug targeting illuminates local kinase action

eLife
2019-12-24 | Journal article
DOI: 10.7554/eLife.52220
Contributors: Paula J Bucko; Chloe K Lombard; Lindsay Rathbun; Irvin Garcia; Akansha Bhat; Linda Wordeman; F Donelson Smith; Dustin J Maly; Heidi Hehnly; John D Scott
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An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

eLife
2019-05-07 | Journal article
DOI: 10.7554/eLife.44187
Contributors: Rigney E Turnham; F Donelson Smith; Heidi L Kenerson; Mitchell H Omar; Martin Golkowski; Irvin Garcia; Renay Bauer; Ho-Tak Lau; Kevin M Sullivan; Lorene K Langeberg et al.
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Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

Proceedings of the National Academy of Sciences
2018-12-04 | Journal article
DOI: 10.1073/pnas.1816614115
Contributors: F. Donelson Smith; Mitchell H. Omar; Patrick J. Nygren; Joseph Soughayer; Naoto Hoshi; Ho-Tak Lau; Calvin G. Snyder; Tess C. Branon; Debapriya Ghosh; Lorene K. Langeberg et al.
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Protein kinase A activation: Something new under the sun?

Journal of Cell Biology
2018-06-04 | Journal article
DOI: 10.1083/jcb.201805011
Contributors: F. Donelson Smith; John D. Scott
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Local protein kinase A action proceeds through intact holoenzymes

Science
2017-06-23 | Journal article
DOI: 10.1126/science.aaj1669
Contributors: F. Donelson Smith; Jessica L. Esseltine; Patrick J. Nygren; David Veesler; Dominic P. Byrne; Matthias Vonderach; Ilya Strashnov; Claire E. Eyers; Patrick A. Eyers; Lorene K. Langeberg et al.
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