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Employment (2)

Harvard University T H Chan School of Public Health: Boston, MA, US

2016-09-01 to 2023-06-16 | Laboratory Manager (Environmental Health)
Employment
Source: Self-asserted source
Cameron Fraser

Dana-Farber/Harvard Cancer Center: MA, MA, US

2014-11-01 to 2016-08-31 | Research Technician
Employment
Source: Self-asserted source
Cameron Fraser

Education and qualifications (1)

Harvard University: Boston, MA, US

2023-07-01 to present | Biological Sciences in Public Health (Molecular Metabolism)
Education
Source: Self-asserted source
Cameron Fraser

Works (28)

Data from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S1 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S2 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S3 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S4 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S5 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S6 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Figure S7 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

Cancer Research
2025-03-03 | Journal article
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Supplemental figures from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Table S3 from Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

2025-03-03 | Preprint
Contributors: Luiza Martins Nascentes Melo; Marie Sabatier; Vijayashree Ramesh; Krystina J. Szylo; Cameron S. Fraser; Alex Pon; Evann C. Mitchell; Kelly A. Servage; Gabriele Allies; Isa V. Westedt et al.
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Crossref

Functional genomic screens with death rate analyses reveal mechanisms of drug action

Nature Chemical Biology
2024-11 | Journal article
Contributors: Megan E. Honeywell; Marie S. Isidor; Nicholas W. Harper; Rachel E. Fontana; Gavin A. Birdsall; Peter Cruz-Gordillo; Sydney A. Porto; Madison Jerome; Cameron S. Fraser; Kristopher A. Sarosiek et al.
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Data from Radiation therapy-induced neurocognitive impairment is driven by heightened apoptotic priming in early life and prevented by blocking BAX

2024-09-16 | Preprint
Contributors: Rumani Singh; Stacey Yu; Marwa Osman; Zintis Inde; Cameron Fraser; Abigail H. Cleveland; Nicole Almanzar; Chuan Bian Lim; Gaurav N. Joshi; Johan Spetz et al.
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Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX

Cancer Research
2023-10-13 | Journal article
Contributors: Rumani Singh; Stacey Yu; Marwa Osman; Zintis Inde; Cameron Fraser; Abigail H. Cleveland; Nicole Almanzar; Chuan Bian Lim; Gaurav N. Joshi; Johan Spetz et al.
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Preferred source (of 16)‎

LKB1 loss rewires JNK-induced apoptotic protein dynamics through NUAKs and sensitizes KRAS-mutant NSCLC to combined KRASG12C + MCL-1 blockade

2022-12-06 | Preprint
Contributors: Aaron Hata; Chendi Li; Mohammed Syed; Yi Shen; Cameron Fraser; Jian Ouyang; Johannes Kreuzer; Sarah Clark; Audris Oh; Makeba Walcott et al.
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Crossref

Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy–induced toxicities

Science Advances
2022-11-11 | Journal article
Contributors: Johan K. E. Spetz; Mary H. C. Florido; Cameron S. Fraser; Xingping Qin; Jonathan Choiniere; Stacey J. Yu; Rumani Singh; Max Friesen; Lee L. Rubin; Joe-Elie Salem et al.
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Crossref

A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Antiapoptotic Protein in Kidney Cancer

Clinical Cancer Research
2022-11-01 | Journal article
Contributors: Treg Grubb; Smruthi Maganti; John Michael Krill-Burger; Cameron Fraser; Laura Stransky; Tomas Radivoyevitch; Kristopher A. Sarosiek; Francisca Vazquez; William G. Kaelin, Jr; Abhishek A. Chakraborty
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Preferred source (of 21)‎

Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics

Nature Communications
2022-10-02 | Journal article
Contributors: Cameron S. Fraser; Johan K. E. Spetz; Xingping Qin; Adam Presser; Jonathan Choiniere; Chendi Li; Stacey Yu; Frances Blevins; Aaron N. Hata; Jeffrey W. Miller et al.
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Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Blood
2019-11 | Journal article
Part of ISSN: 0006-4971
Contributors: Renata Grozovsky; Cameron Fraser; Karin M. Hoffmeister; Kristopher Sarosiek; Silvia Giannini
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Cancer Discovery
2019-04 | Journal article
Part of ISSN: 2159-8274
Contributors: Chen Lossos; Yunpeng Liu; Kellie E. Kolb; Amanda L. Christie; Alexandria Van Scoyk; Sanjay M. Prakadan; Kay Shigemori; Kristen E. Stevenson; Sara Morrow; Olivia D. Plana et al.
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies

Methods in Molecular Biology
2018 | Other
Part of ISSN: 1064-3745
Contributors: Cameron Fraser; Jeremy Ryan; Kristopher Sarosiek
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Clonal Plasma Cells in AL Amyloidosis Are Dependent on Anti-Apoptotic BCL-2 Family Proteins

Blood
2018-11 | Journal article
Part of ISSN: 0006-4971
Contributors: Cameron Fraser; Vaishali Sanchorawala; Kristopher Sarosiek; Shayna Sarosiek
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non–Small Cell Lung Cancer

Cancer Discovery
2018-09 | Journal article
Part of ISSN: 2159-8274
Contributors: Varuna Nangia; Faria M. Siddiqui; Sean Caenepeel; Daria Timonina; Samantha J. Bilton; Nicole Phan; Maria Gomez-Caraballo; Hannah L. Archibald; Chendi Li; Cameron Fraser et al.
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics

Cancer Cell
2017-01 | Journal article
Part of ISSN: 1535-6108
Contributors: Kristopher A. Sarosiek; Cameron Fraser; Nathiya Muthalagu; Patrick D. Bhola; Weiting Chang; Samuel K. McBrayer; Adam Cantlon; Sudeshna Fisch; Gail Golomb-Mello; Jeremy A. Ryan et al.
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Clonal Evolution In Patients With Chronic Lymphocytic Leukemia (CLL) Developing Resistance To BTK Inhibition

Blood
2013-11 | Journal article
Part of ISSN: 0006-4971
Contributors: Jan A. Burger; Dan Landau; Julia Hoellenriegel; Carrie Sougnez; Matthias Schlesner; Naveed Ishaque; Benedikt Brors; Michael J. Keating; William G. Wierda; Kristian Cibulskis et al.
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Cameron Fraser via Crossref Metadata Search

A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer

Other
Contributors: Treg Grubb; Smruthi Maganti; John Michael Krill-Burger; Cameron Fraser; Laura Stransky; Tomas Radivoyevitch; Kristopher A. Sarosiek; Francisca Vazquez; William G. Kaelin; Abhishek A. Chakraborty
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity

Other
Contributors: Zintis Inde; Clarence Yapp; Gaurav N. Joshi; Johan Spetz; Cameron Fraser; Brian Deskin; Elisa Ghelfi; Chhinder Sodhi; David J. Hackam; Lester Kobzik et al.
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search

Clonal plasma cells in AL amyloidosis are dependent on pro survival BCL-2 family proteins and sensitive to BH3 mimetics

Other
Contributors: Cameron Fraser; Adam Presser; Vaishali Sanchorawala; Shayna Sarosiek; Kristopher Sarosiek
Source: Self-asserted source
Cameron Fraser via Crossref Metadata Search