Personal information

Websites & social links

http://www.ibmb.csic.es/groups/molecular-mechanisms-of-signaling-through-g-proteins

Other IDs

ResearcherID: K-3813-2014

Keywords

Biomedicine, Signal transduction, Cell Biology, Mitochondria

Activities

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Employment (1)

Fundación General CSIC: Barcelona, ES

2006-07-21 to present | Associate Professor (Molecular Biology Institute of Barcelona (IMBM))
Employment
Source: Self-asserted source
Anna Aragay

Education and qualifications (3)

Autonomous University of Barcelona: Barcelona, Barcelona, ES

1985-01-01 to 1989-11-24 | PhD (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Anna Aragay

Autonomous University of Barcelona: Barcelona, Barcelona, ES

1983-09-01 to 1984-02-02 | Master (tesina) (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Anna Aragay

Autonomous University of Barcelona: Barcelona, Barcelona, ES

1978-09-15 to 1982-06-31 | Bachelor (Chemistry)
Education
Source: Self-asserted source
Anna Aragay

Funding (14)

Gq: de la mitocondria a los cardiomiocitos

2015-01 to 2017-12 | Grant
Ministerio de Ciencia y Tecnología (Madrid, ES)
GRANT_NUMBER:

BFU2014-53978-R

Source: Self-asserted source
Anna Aragay

Procesos de señalización por proteínas G implicados en migración cellular

2012-01 to 2014-12 | Grant
Ministerio de Ciencia y Tecnología (Madrid, ES)
GRANT_NUMBER:

BFU2011-30080
Source: Self-asserted source
Anna Aragay

Mecanisme i funció del tràfic endocític

2009-01 to 2014-12 | Grant
Agència de Gestió d’Ajuts Universitaris i de Recerca (Barcelona, ES)
Part of GRANT_NUMBER:

SRG 4163
Source: Self-asserted source
Anna Aragay

Estudio de la interacción de la proteína G12 con p120 catenina

2009-01 to 2011-12 | Grant
Ministerio de Ciencia y Tecnología (Madrid, ES)
GRANT_NUMBER:

BFU2008-04262
Source: Self-asserted source
Anna Aragay

Imaging G proteins in Cell adhesion and migration

2008-01 to 2009-12 | Grant
Helse Vest (Bergen, NO)
GRANT_NUMBER:

12458
Source: Self-asserted source
Anna Aragay

Estudio del papel de la proteína G12

2007-01 to 2017-12 | Grant
Fundación General CSIC (Madrid, ES)
GRANT_NUMBER:

Proyecto intramural
Source: Self-asserted source
Anna Aragay

Signalling in cancer

2006-01 to 2007-12 | Grant
Norwegian Cancer Society (Oslo, NO)
GRANT_NUMBER:

GRANT NUMBER A06110

Source: Self-asserted source
Anna Aragay

Characterization of type II GnRH receptor internalization

2005-01 to 2006-12 | Grant
Norwegian Research Council. Norway (Bergen, NO)
GRANT_NUMBER:

06/175 FA/HS
Source: Self-asserted source
Anna Aragay
grade
Preferred source (of 2)‎

In vivo vivo Imaging system

2003-01 to 2004-12 | Grant
Norges Forskningsråd (Oslo, NO)
GRANT_NUMBER:

158305/V00

Source: Self-asserted source
Anna Aragay

Molecular Imaging Platform

2002-01 to 2006-12 | Grant
Norges Forskningsråd (Oslo, NO)
Part of GRANT_NUMBER:

FUGE
Source: Self-asserted source
Anna Aragay

Migratory behaviour of cells in tumours. The role of G proteins

2002-01 to 2003-12 | Grant
Norges Forskningsråd (Oslo, NO)
GRANT_NUMBER:

147604.
Source: Self-asserted source
Anna Aragay

Regulation of G protein signaling in the hematopoietic system

2001-01 to 2002-12 | Grant
Norwegian Cancer Society (Oslo, NO)
GRANT_NUMBER:

A00003
Source: Self-asserted source
Anna Aragay

Deciphering the chemokine signal transduction pathways

2000-01 to 2003-12 | Grant
Norges Forskningsråd (Oslo, NO)
GRANT_NUMBER:

135757/310
Source: Self-asserted source
Anna Aragay

Regulation of G protein signaling in the hematopoietic system

2000-01 to 2001-12 | Grant
Norwegian Cancer Society (Oslo, NO)
Source: Self-asserted source
Anna Aragay

Works (40)

A mammalian-specific Alex3/Gα <sub>q</sub> protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival

Science Signaling
2024-02-06 | Journal article | Author
DOI: 10.1126/scisignal.abq1007
Part of ISSN: 1945-0877
Part of ISSN: 1937-9145
Contributors: Ismael Izquierdo Villalba; Serena Mirra; Yasmina Manso Sanz; Antoni Parcerisas; Javier Rubio; Jaume del valle; Francisco J. Gil-Bea; Fausto Ulloa; Marina Herrero-Lorenzo; Ester Verdaguer et al.
Source: Self-asserted source
Anna Aragay

Kazrin promotes dynein/dynactin-dependent traffic from early to recycling endosomes

eLife
2023-04-25 | Journal article
DOI: 10.7554/elife.83793
Part of ISSN: 2050-084X
Contributors: Ines Hernandez-Perez; Javier Rubio; Adrian Baumann; Henrique Girao; Miriam Ferrando; Elena Rebollo; Anna M Aragay; Maria Isabel Geli
Source: Self-asserted source
Anna Aragay

Gq Signaling in Autophagy Control: Between Chemical and Mechanical Cues

Antioxidants
2022-08-18 | Journal article
DOI: 10.3390/antiox11081599
Part of ISSN: 2076-3921
Contributors: Inmaculada Navarro-Lérida; Anna M. Aragay; Alejandro Asensio; Catalina Ribas Nuñez
Source: Self-asserted source
Anna Aragay

Gαq activation modulates autophagy by promoting mTORC1 signaling

Nature Communications
2021-12 | Journal article
DOI: 10.1038/s41467-021-24811-4
Part of ISSN: 2041-1723
Source: Self-asserted source
Anna Aragay

Kazrin is an endosomal adaptor for dynein/dynactin

2021-08-31 | Preprint
DOI: 10.1101/2021.08.30.458243
Contributors: Ines Hernandez-Perez; Adrian Baumann; Javier Rubio; Henrique Girao; Elena Rebollo; Anna M. Aragay; Maria Isabel Geli
Source: Self-asserted source
Anna Aragay

An Overview on G Protein-coupled Receptor-induced Signal Transduction in Acute Myeloid Leukemia

Current Medicinal Chemistry
2019-10-25 | Journal article
DOI: 10.2174/0929867326666190429153247
Part of ISSN: 0929-8673
Contributors: Frode Selheim; Elise Aasebø; Catalina Ribas; Anna M. Aragay
Source: Self-asserted source
Anna Aragay

Regulation of chemokine receptor CCR2 recycling by filamin a phosphorylation

Journal of Cell Science
2016-01-01 | Journal article
DOI: 10.1242/jcs.193821
Contributors: Mònica Pons; Ismael Izquierdo; Mireia Andreu-Carbó; Georgina Garrido; Jesús Planagumà; Olivia Muriel; M. Isabel Geli; Anna M. Aragay
Source: check_circle
Crossref

Gastrin-stimulated Gα13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells.

2015-06 | Journal article
DOI: 10.1074/jbc.m114.628164
PMID: 25922072
PMC: PMC4463461
Contributors: Masià-Balagué M; Izquierdo I; Garrido G; Cordomí A; Pérez-Benito L; Miller NL; Schlaepfer DD; Gigoux V; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression.

2014-07 | Journal article
DOI: 10.1016/j.bbrc.2014.05.032
PMID: 24845383
Contributors: Nygaard G; Herfindal L; Kopperud R; Aragay AM; Holmsen H; Døskeland SO; Kleppe R; Selheim F
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

A new non-canonical pathway of Gα(q) protein regulating mitochondrial dynamics and bioenergetics.

2014-05 | Journal article
DOI: 10.1016/j.cellsig.2014.01.009
PMID: 24444709
PMC: PMC4745894
Contributors: Benincá C; Planagumà J; de Freitas Shuck A; Acín-Perez R; Muñoz JP; de Almeida MM; Brown JH; Murphy AN; Zorzano A; Enríquez JA et al.
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Gαq signalling: the new and the old.

2014-05 | Journal article
DOI: 10.1016/j.cellsig.2014.01.010
PMID: 24440667
Contributors: Sánchez-Fernández G; Cabezudo S; García-Hoz C; Benincá C; Aragay AM; Mayor F; Ribas C
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Filamin A-hinge region 1-EGFP: a novel tool for tracking the cellular functions of filamin A in real-time.

2012 | Journal article
DOI: 10.1371/journal.pone.0040864
PMID: 22870205
PMC: PMC3411599
Contributors: Planagumà J; Minsaas L; Pons M; Myhren L; Garrido G; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Gα(12) binds to the N-terminal regulatory domain of p120(ctn), and downregulates p120(ctn) tyrosine phosphorylation induced by Src family kinases via a RhoA independent mechanism.

2011-02 | Journal article
DOI: 10.1016/j.yexcr.2010.10.017
PMID: 20974127
Contributors: Ardawatia VV; Masià-Balagué M; Krakstad BF; Johansson BB; Kreitzburg KM; Spriet E; Lewis AE; Meigs TE; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Filamin a binds to CCR2B and regulates its internalization.

2010-08 | Journal article
DOI: 10.1371/journal.pone.0012212
PMID: 20808917
PMC: PMC2923182
Contributors: Minsaas L; Planagumà J; Madziva M; Krakstad BF; Masià-Balagué M; Katz AA; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits.

2006-01 | Journal article
DOI: 10.1091/mbc.e05-05-0399
PMID: 16221891
PMC: PMC1345643
Contributors: Jiménez-Sainz MC; Murga C; Kavelaars A; Jurado-Pueyo M; Krakstad BF; Heijnen CJ; Mayor F; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Proteasome involvement in the degradation of the G(q) family of Galpha subunits.

2005-10 | Journal article
DOI: 10.1111/j.1742-4658.2005.04934.x
PMID: 16218966
Contributors: Johansson BB; Minsaas L; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

A role for Galpha12/Galpha13 in p120ctn regulation.

2004-07 | Journal article
DOI: 10.1073/pnas.0401366101
PMID: 15240885
PMC: PMC478569
Contributors: Krakstad BF; Ardawatia VV; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation.

2003-09 | Journal article
DOI: 10.1124/mol.64.3.773
PMID: 12920215
Contributors: Jiménez-Sainz MC; Fast B; Mayor F; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Functional regulation of Galpha16 by protein kinase C.

1999-02 | Journal article
DOI: 10.1074/jbc.274.8.4807
PMID: 9988720
Contributors: Aragay AM; Quick MW
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.

1998-07 | Journal article
PMID: 9670957
Contributors: Mellado M; Rodríguez-Frade JM; Aragay A; del Real G; Martín AM; Vila-Coro AJ; Serrano A; Mayor F; Martínez-A C
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

G protein-coupled receptor kinase 2 (GRK2): mechanisms of regulation and physiological functions.

1998-06 | Journal article
DOI: 10.1016/s0014-5793(98)00495-5
PMID: 9678590
Contributors: Aragay AM; Ruiz-Gómez A; Penela P; Sarnago S; Elorza A; Jiménez-Sainz MC; Mayor F
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2.

1998-03 | Journal article
DOI: 10.1073/pnas.95.6.2985
PMID: 9501202
PMC: PMC19681
Contributors: Aragay AM; Mellado M; Frade JM; Martin AM; Jimenez-Sainz MC; Martinez-A C; Mayor F
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Desensitization of inositol 1,4,5-trisphosphate/Ca2+-induced Cl- currents by prolonged activation of G proteins in Xenopus oocytes.

1996-12 | Journal article
DOI: 10.1074/jbc.271.50.32021
PMID: 8943251
Contributors: Quick MW; Lester HA; Davidson N; Simon MI; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina.

1996-11 | Journal article
DOI: 10.1074/jbc.271.45.28154
PMID: 8910430
Contributors: Watson AJ; Aragay AM; Slepak VZ; Simon MI
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells.

1996-11 | Journal article
DOI: 10.1091/mbc.7.11.1679
PMID: 8930892
PMC: PMC276018
Contributors: Post GR; Collins LR; Kennedy ED; Moskowitz SA; Aragay AM; Goldstein D; Brown JH
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells.

Endocrinology
1996-08 | Journal article
DOI: 10.1210/endo.137.8.8754733
Contributors: S Maeda; S Wu; H Jüppner; J Green; A M Aragay; J A Fagin; T L Clemens
Source: Self-asserted source
Anna Aragay via Crossref Metadata Search

Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells.

1996-08 | Journal article
DOI: 10.1210/en.137.8.3154
PMID: 8754733
Contributors: Maeda S; Wu S; Jüppner H; Green J; Aragay AM; Fagin JA; Clemens TL
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Increased expression of alphaq family G-proteins during oocyte maturation and early development of Xenopus laevis.

1996-07 | Journal article
DOI: 10.1006/dbio.1996.0164
PMID: 8660896
Contributors: Gallo CJ; Jones TL; Aragay AM; Jaffe LA
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

G12 requirement for thrombin-stimulated gene expression and DNA synthesis in 1321N1 astrocytoma cells.

1995-08 | Journal article
DOI: 10.1074/jbc.270.34.20073
PMID: 7650024
Contributors: Aragay AM; Collins LR; Post GR; Watson AJ; Feramisco JR; Brown JH; Simon MI
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Design of degenerate oligonucleotide primers for cloning of G-protein alpha subunits.

1994 | Journal article
DOI: 10.1016/s0076-6879(94)37073-7
PMID: 7523836
Contributors: Wilkie TM; Aragay AM; Watson AJ; Simon MI
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes.

1994-12 | Journal article
PMID: 7982922
Contributors: Quick MW; Simon MI; Davidson N; Lester HA; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Narrow A/T-rich zones present at the distal 5'-flanking sequences of the zein genes Zc1 and Zc2 bind a unique 30 kDa HMG-like protein.

1994-12 | Journal article
DOI: 10.1007/bf00019501
PMID: 7858225
Contributors: Ponte I; Guillén P; Debón RM; Reina M; Aragay A; Espel E; Di Fonzo N; Palau J
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Random mutagenesis of G protein alpha subunit G(o)alpha. Mutations altering nucleotide binding.

1993-10 | Journal article
PMID: 8408043
Contributors: Slepak VZ; Quick MW; Aragay AM; Davidson N; Lester HA; Simon MI
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells.

1992-12 | Journal article
PMID: 1334076
Contributors: Aragay AM; Katz A; Simon MI
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Different mechanism for in vitro formation of nucleosome core particles.

1991-05 | Journal article
DOI: 10.1021/bi00234a026
PMID: 2036369
Contributors: Aragay AM; Fernandez-Busquets X; Daban JR
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

The b-32 protein from maize endosperm: characterization of genomic sequences encoding two alternative central domains.

1990-06 | Journal article
DOI: 10.1007/bf00019399
PMID: 2102870
Contributors: Hartings H; Lazzaroni N; Marsan PA; Aragay A; Thompson R; Salamini F; Di Fonzo N; Palau J; Motto M
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Association of nucleosome core particle DNA with different histone oligomers. Transfer of histones between DNA-(H2A,H2B) and DNA-(H3,H4) complexes.

1988-11 | Journal article
DOI: 10.1016/0022-2836(88)90605-5
PMID: 3216389
Contributors: Aragay AM; Diaz P; Daban JR
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

A fluorescent method for the rapid staining and quantitation of proteins in sodium dodecyl sulfate-polyacrylamide gels

Electrophoresis
1985 | Journal article
DOI: 10.1002/elps.1150061102
Contributors: Anna M. Aragay; Pilar Diaz; Joan-Ramon Daban
Source: Self-asserted source
Anna Aragay via Crossref Metadata Search

Fluorescent properties of histone-1-anilinonaphthalene 8-sulfonate complexes in the presence of denaturant agents: application to the rapid staining of histones in urea and Triton-urea-polyacrylamide gels.

1985-05 | Journal article
DOI: 10.1016/0003-2697(85)90564-0
PMID: 4025806
Contributors: Piña B; Aragay AM; Suau P; Daban JR
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Rapid fluorescent staining of histones in sodium dodecyl sulfate-polyacrylamide gels.

1984-04 | Journal article
DOI: 10.1016/0003-2697(84)90792-9
PMID: 6203437
Contributors: Daban JR; Aragay AM
Source: Self-asserted source
Anna Aragay via Europe PubMed Central

Peer review (2 reviews for 1 publication/grant)

Review activity for Experimental cell research. (2)
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