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China

Activities

Employment (3)

Institute of Genetics and Developmental Biology Chinese Academy of Sciences: Beijing, Beijing, CN

2017-05-26 to present | Investigator
Employment
Source: Self-asserted source
Falong Lu

Children's Hospital Boston: Boston, MA, US

2012-08-15 to 2017-05-25 | Postdoctoral fellow (Program of Cellular and Molecular Medicine)
Employment
Source: Self-asserted source
Falong Lu

University of North Carolina at Chapel Hill: Chapel Hill, NC, US

2012-01-27 to 2012-08-14 | Postdoctoral fellow
Employment
Source: Self-asserted source
Falong Lu

Education and qualifications (2)

Institute of Genetics and Developmental Biology Chinese Academy of Sciences: Beijing, Beijing, CN

2004-09-01 to 2011-07-07 | Ph.D.
Education
Source: Self-asserted source
Falong Lu

Peking University: Beijing, Beijing, CN

2000-09-01 to 2004-06-31 | B.S. (School of Life Sciences)
Education
Source: Self-asserted source
Falong Lu

Works (50 of 56)

Items per page:
Page 1 of 2

KDM2A and KDM2B protect a subset of CpG islands from DNA methylation

Journal of Genetics and Genomics
2025-01 | Journal article
Contributors: Yuan Liu; Ying Liu; Yunji Zhu; Di Hu; Hu Nie; Yali Xie; Rongrong Sun; Jin He; Honglian Zhang; Falong Lu
Source: check_circle
Crossref

MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA

Nature Communications
2025-01-02 | Journal article
Contributors: Jing Yang; Jiachen Bu; Bowen Liu; Yusheng Liu; Zhuqiang Zhang; Ziyi Li; Falong Lu; Bing Zhu; Yingfeng Li
Source: check_circle
Crossref

Beyond simple tails: poly(A) tail-mediated RNA epigenetic regulation

Trends in Biochemical Sciences
2024-10 | Journal article
Contributors: Jingwen Liu; Falong Lu
Source: check_circle
Crossref

Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos

Nature Structural & Molecular Biology
2024-09 | Journal article
Contributors: Jiaqiang Wang; Yiwei Zhang; Jiaze Gao; Guihai Feng; Chao Liu; Xueke Li; Pengcheng Li; Zhonghua Liu; Falong Lu; Leyun Wang et al.
Source: check_circle
Crossref

Embryo spatial 3D genomics

2024-05-10 | Preprint
Contributors: Yuang Ma; Bo Gou; Yuetong Xu; Muya Shu; Falong Lu; Xiang Li
Source: check_circle
Crossref

The piRNA size matters

National Science Review
2024-01-09 | Journal article
Contributors: Jingwen Liu; Falong Lu
Source: check_circle
Crossref

m6A-modified RNAs possess distinct poly(A) tails

Journal of Genetics and Genomics
2023-03 | Journal article
Contributors: Shuang Wu; Yiwei Zhang; Lan Yao; Jiaqiang Wang; Falong Lu; Yusheng Liu
Source: check_circle
Crossref

Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis

Briefings in Bioinformatics
2023-01-19 | Journal article
Contributors: Danni Hong; Hongli Lin; Lifang Liu; Muya Shu; Jianwu Dai; Falong Lu; Mengsha Tong; Jialiang Huang
Source: check_circle
Crossref

Transcriptome-wide measurement of poly(A) tail length and composition at subnanogram total RNA sensitivity by PAIso-seq

Nature Protocols
2022-09 | Journal article
Contributors: Yusheng Liu; Yiwei Zhang; Jiaqiang Wang; Falong Lu
Source: check_circle
Crossref

Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis

2022-05-20 | Preprint
Contributors: Danni Hong; Hongli Lin; Lifang Liu; Muya Shu; Jianwu Dai; Falong Lu; Mengsha Tong; Jialiang Huang
Source: check_circle
Crossref

BAP60 plays an opposite role to the MRT-NURF complex in regulating lipid droplet size

Journal of Genetics and Genomics
2022-04 | Journal article
Contributors: Yan Yao; Mengyao Xu; Lianyong Qiao; Hu Nie; Falong Lu; Xun Huang
Source: check_circle
Crossref

Abundant non-A residues in the poly(A) tail orchestrate the mouse oocyte-to-embryo transition

2021-08-31 | Other
Contributors: Yusheng Liu; Hu Nie; Le-Yun Wang; Shuang Wu; Wei Li; Qi Zhou; Jiaqiang Wang; Falong Lu
Source: check_circle
Crossref

Conservation and divergence of poly(A) tail regulation during the mammalian oocyte-to-embryo transition

2021-08-31 | Other
Contributors: Yusheng Liu; Junxue Jin; Yiwei Zhang; Le-Yun Wang; Chuanxin Zhang; Zhenzhen Hou; Wei Li; Zhonghua Liu; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Dynamics of mitochondrial mRNA abundance and poly(A) tail during the mammalian oocyte-to-embryo transition

2021-08-31 | Other
Contributors: Yusheng Liu; Yiwei Zhang; Zhonghua Liu; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Enhancement of synthetic mRNA translation efficiency through engineered poly(A) tails

2021-08-31 | Other
Contributors: Yusheng Liu; Hu Nie; Rongrong Sun; Jiaqiang Wang; Falong Lu
Source: check_circle
Crossref

Poly(A) tail length is a major regulator of maternal gene expression during the mammalian oocyte-to-embryo transition

2021-08-31 | Other
Contributors: Yusheng Liu; Hu Nie; Chuanxin Zhang; Zhenzhen Hou; Jiaqiang Wang; Falong Lu
Source: check_circle
Crossref

Degradation intermediates as an indicator of mRNA and cell metabolism

2021-08-30 | Other
Contributors: Yusheng Liu; Yiwei Zhang; Hu Nie; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes

2021-08-30 | Other
Contributors: Yusheng Liu; Wenrong Tao; Yiwei Zhang; Hu Nie; Zhenzhen Hou; Jingye Zhang; Zhen Yang; Jiaqiang Wang; Falong Lu; Keliang Wu
Source: check_circle
Crossref

Comprehensive analysis of mRNA poly(A) tail reveals complex and conserved regulation

2021-08-29 | Other
Contributors: Yusheng Liu; Hu Nie; Yiwei Zhang; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Interactions between RNA m6A modification, alternative splicing, and poly(A) tail revealed by MePAIso-seq2

2021-08-29 | Other
Contributors: Yusheng Liu; Yiwei Zhang; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Mitochondrial mRNA is a stable and convenient reference for the normalization of RNA-seq data

2021-08-29 | Other
Contributors: Yusheng Liu; Yiwei Zhang; Falong Lu; Jiaqiang Wang
Source: check_circle
Crossref

Re-polyadenylation occurs predominantly on maternal mRNA degradation intermediates during mammalian oocyte-to-embryo transition

2021-08-29 | Other
Contributors: Yusheng Liu; Yiwei Zhang; Hu Nie; Zhonghua Liu; Jiaqiang Wang; Falong Lu
Source: check_circle
Crossref

Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice

Nature Communications
2021-04-16 | Journal article
Contributors: Wenhui Mu; Si Li; Jingkai Xu; Xize Guo; Haoda Wu; Zhenhua Chen; Lianyong Qiao; Gisela Helfer; Falong Lu; Chong Liu et al.
Source: check_circle
Crossref

Dynamic RNA 3′ Uridylation and Guanylation during Mitosis

iScience
2020-08 | Journal article
Contributors: Yusheng Liu; Hu Nie; Falong Lu
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer

Cell Stem Cell
2020-06 | Journal article
Part of ISSN: 1934-5909
Source: Self-asserted source
Falong Lu

Rett mutations attenuate phase separation of MeCP2

Cell Discovery
2020-06-16 | Journal article
Contributors: Chunyan Fan; Honglian Zhang; Liangzheng Fu; Yuejiao Li; Yi Du; Zilong Qiu; Falong Lu
Source: check_circle
Crossref

Poly(A) inclusive RNA isoform sequencing (PAIso−seq) reveals wide-spread non-adenosine residues within RNA poly(A) tails

Nature Communications
2019-11-22 | Journal article
Contributors: Yusheng Liu; Hu Nie; Hongxiang Liu; Falong Lu
Source: check_circle
Crossref

In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function

Nature Communications
2019-06-07 | Journal article
Contributors: Luis M. Tuesta; Mohamed N. Djekidel; Renchao Chen; Falong Lu; Wengang Wang; Bernardo L. Sabatini; Yi Zhang
Source: check_circle
Crossref

DNA methylation repels targeting of Arabidopsis REF6

Nature Communications
2019-05-02 | Journal article
Contributors: Qi Qiu; Hailiang Mei; Xian Deng; Kaixuan He; Baixing Wu; Qingqing Yao; Jixiang Zhang; Falong Lu; Jinbiao Ma; Xiaofeng Cao
Source: check_circle
Crossref

Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development

Cell Stem Cell
2018 | Journal article
EID:

2-s2.0-85055934370

Contributors: Matoba, S.; Wang, H.; Jiang, L.; Lu, F.; Iwabuchi, K.A.; Wu, X.; Inoue, K.; Yang, L.; Press, W.; Lee, J.T. et al.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Reprogramming of Chromatin Accessibility in Somatic Cell Nuclear Transfer Is DNA Replication Independent

Cell Reports
2018 | Journal article
EID:

2-s2.0-85046732267

Contributors: Djekidel, M.N.; Inoue, A.; Matoba, S.; Suzuki, T.; Zhang, C.; Lu, F.; Jiang, L.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

The start of a human life program

Journal of Genetics and Genomics
2018-04 | Journal article
Contributors: Falong Lu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genomic imprinting of Xist by maternal H3K27me3

Genes and Development
2017 | Journal article
EID:

2-s2.0-85032915217

Contributors: Inoue, A.; Jiang, L.; Lu, F.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Maternal H3K27me3 controls DNA methylation-independent imprinting

Nature
2017 | Journal article
EID:

2-s2.0-85026357924

Contributors: Inoue, A.; Jiang, L.; Lu, F.; Suzuki, T.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Drosophila Homolog of FMRP Maintains Genome Integrity by Interacting with Piwi

Journal of Genetics and Genomics
2016 | Journal article
EID:

2-s2.0-84957846172

Contributors: Jiang, F.; Lu, F.; Li, P.; Liu, W.; Zhao, L.; Wang, Q.; Cao, X.; Zhang, L.; Zhang, Y.Q.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Establishing chromatin regulatory landscape during mouse preimplantation development

Cell
2016 | Journal article
EID:

2-s2.0-84971569678

Contributors: Lu, F.; Liu, Y.; Inoue, A.; Suzuki, T.; Zhao, K.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer

Cell Reports
2016 | Journal article
EID:

2-s2.0-84989853721

Contributors: Kim, M.; Lu, F.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis

Nature Genetics
2016 | Journal article
EID:

2-s2.0-84964199681

Contributors: Cui, X.; Lu, F.; Qiu, Q.; Zhou, B.; Gu, L.; Zhang, S.; Kang, Y.; Cui, X.; Ma, X.; Yao, Q. et al.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association

Cell Discovery
2015 | Journal article
Source: Self-asserted source
Falong Lu

Cell totipotency: Molecular features, induction, and maintenance

National Science Review
2015 | Journal article
EID:

2-s2.0-84936933767

Contributors: Lu, F.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells

Cell Stem Cell
2015 | Journal article
EID:

2-s2.0-84951963344

Contributors: Chung, Y.G.; Matoba, S.; Liu, Y.; Eum, J.H.; Lu, F.; Jiang, W.; Lee, J.E.; Sepilian, V.; Cha, K.Y.; Lee, D.R. et al.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Arabidopsis protein arginine methyltransferase 3 is required for ribosome biogenesis by affecting precursor ribosomal RNA processing

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
EID:

2-s2.0-84909606737

Contributors: Hang, R.; Liu, C.; Ahmad, A.; Zhang, Y.; Lu, F.; Cao, X.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation

Cell
2014 | Journal article
EID:

2-s2.0-84910092474

Contributors: Matoba, S.; Liu, Y.; Lu, F.; Iwabuchi, K.A.; Shen, L.; Inoue, A.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Role of Tet proteins in enhancer activity and telomere elongation

Genes and Development
2014 | Journal article
EID:

2-s2.0-84907507329

Contributors: Lu, F.; Liu, Y.; Jiang, L.; Yamaguchi, S.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes

Cell Stem Cell
2014 | Journal article
EID:

2-s2.0-84914818905

Contributors: Shen, L.; Inoue, A.; He, J.; Liu, Y.; Lu, F.; Zhang, Y.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Ubiquitin-specific proteases UBP12 and UBP13 act in circadian clock and photoperiodic flowering regulation in Arabidopsis

Plant Physiology
2013 | Journal article
EID:

2-s2.0-84878452445

Contributors: Cui, X.; Lu, F.; Li, Y.; Xue, Y.; Kang, Y.; Zhang, S.; Qiu, Q.; Zheng, X.C.; Cui, X.; Zheng, S. et al.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

The enzymatic activity of Arabidopsis protein arginine methyltransferase 10 is essential for flowering time regulation

Protein and Cell
2012 | Journal article
EID:

2-s2.0-84863487964

Contributors: Niu, L.; Lu, F.; Zhao, T.; Liu, C.; Cao, X.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Arabidopsis REF6 is a histone H3 lysine 27 demethylase

Nature Genetics
2011 | Journal article
EID:

2-s2.0-79959741225

Contributors: Lu, F.; Cui, X.; Zhang, S.; Jenuwein, T.; Cao, X.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Crystal structure of the plant epigenetic protein arginine methyltransferase 10

Journal of Molecular Biology
2011 | Journal article
EID:

2-s2.0-81055156654

Contributors: Cheng, Y.; Frazier, M.; Lu, F.; Cao, X.; Redinbo, M.R.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier

Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing

Proceedings of the National Academy of Sciences of the United States of America
2010 | Journal article
EID:

2-s2.0-78650488766

Contributors: Deng, X.; Gu, L.; Liu, C.; Lu, T.; Lu, F.; Lu, Z.; Cui, P.; Pei, Y.; Wang, B.; Hu, S. et al.
Source: Self-asserted source
Falong Lu via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (24 reviews for 11 publications/grants)

Review activity for Advanced science. (3)
Review activity for Cell discovery. (1)
Review activity for Cell insight. (1)
Review activity for Cell reports. (2)
Review activity for Developmental cell. (2)
Review activity for Gene. (1)
Review activity for Genome biology. (1)
Review activity for Genomics, Proteomics & Bioinformatics. (3)
Review activity for Journal of Genetics and Genomics. (2)
Review activity for Nature communications (7)
Review activity for Nature protocols (1)