Personal information

cancer genomics, bioinformatics, gene regulation, cell biology
Australia

Activities

Employment (1)

Children's Medical Research Institute: Sydney, NSW, AU

2018-02-01 to present | Postdoctoral Research Scientist and NHMRC Early Career Research Fellow (ProCan)
Employment
Source: Self-asserted source
Rebecca Poulos

Education and qualifications (4)

University of New South Wales: Sydney, NSW, AU

2015-02-02 to 2018-03-21 | Doctor of Philosophy
Education
Source: Self-asserted source
Rebecca Poulos

University of New South Wales: Sydney, NSW, AU

2014-01-01 to 2014-12-31 | BSc Hons (First class, with University Medal)
Education
Source: Self-asserted source
Rebecca Poulos

University of Technology Sydney: Broadway, NSW, AU

2011-01-01 to 2013-12-31 | Bachelor of Science (Biotechnology, First in cohort)
Education
Source: Self-asserted source
Rebecca Poulos

University of Technology Sydney: Broadway, NSW, AU

2009-01-01 to 2013-12-31 | Bachelor of Business (Accounting, First in cohort)
Education
Source: Self-asserted source
Rebecca Poulos

Works (50 of 57)

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Page 1 of 2

Potent synthetic lethality between PLK1 and EYA-family inhibitors in tumours of the central and peripheral nervous system

2025-01-22 | Preprint
Contributors: Christopher B. Nelson; Jadon K. Wells; Ekaagra Kesarwani; Alexander P. Sobinoff; Jixuan Gao; Karen L. MacKenzie; Rebecca C. Poulos; Urwah Nawaz; Xiang Wang; Heide L. Ford et al.
Source: check_circle
Crossref

Data from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 1 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 2 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 3 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 4 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 5 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 6 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure 7 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure S1 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure S2 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure S3 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure S4 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Figure S5 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Materials and Methods from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S1 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S2 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S3 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S4 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S5 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S6 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S7 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S8 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Table S9 from DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

2024-12-18 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

Cancer Research Communications
2024-12-01 | Journal article
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Proteomic insights into paediatric cancer: Unravelling molecular signatures and therapeutic opportunities

Pediatric Blood & Cancer
2024-06 | Journal article
Contributors: Bhavna D. Padhye; Urwah Nawaz; Peter G. Hains; Roger R. Reddel; Phillip J. Robinson; Qing Zhong; Rebecca C. Poulos
Source: check_circle
Crossref

Transformer-based deep learning integrates multi-omic data with cancer pathways

2022-10-31 | Preprint
Contributors: Zhaoxiang Cai; Rebecca C. Poulos; Adel Aref; Phillip J. Robinson; Roger R. Reddel; Qing Zhong
Source: check_circle
Crossref

Role of POT1 in Human Cancer

Cancers
2020-09-24 | Journal article
Contributors: Yangxiu Wu; Rebecca C. Poulos; Roger R. Reddel
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Strategies to enable large-scale proteomics for reproducible research

Nature Communications
2020-07-30 | Journal article
Contributors: Rebecca C. Poulos; Peter G. Hains; Rohan Shah; Natasha Lucas; Dylan Xavier; Srikanth S. Manda; Asim Anees; Jennifer M. S. Koh; Sadia Mahboob; Max Wittman et al.
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Crossref

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

PLOS Genetics
2020-02-03 | Journal article
Contributors: Hu Fang; Dmitry A. Gordenin; Jayne A. Barbour; Rebecca C. Poulos; Riku Katainen; Lauri A. Aaltonen; Jason W. H. Wong
Source: check_circle
Crossref

Finding cancer driver mutations in the era of big data research

Biophysical Reviews
2019 | Journal article
EID:

2-s2.0-85061767647

Contributors: Poulos, R.C.; Wong, J.W.H.
Source: Self-asserted source
Rebecca Poulos via Scopus - Elsevier

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

Nature Communications
2019-07-25 | Journal article
Contributors: Matthew Wong; Yuting Sun; Zhichao Xi; Giorgio Milazzo; Rebecca C. Poulos; Christoph Bartenhagen; Jessica L. Bell; Chelsea Mayoh; Nicholas Ho; Andrew E. Tee et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

Cancer Cell
2018 | Journal article
EID:

2-s2.0-85056855732

Contributors: Jing, D.; Huang, Y.; Liu, X.; Sia, K.C.S.; Zhang, J.C.; Tai, X.; Wang, M.; Toscan, C.E.; McCalmont, H.; Evans, K. et al.
Source: Self-asserted source
Rebecca Poulos via Scopus - Elsevier

Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

Biomarker Research
2018 | Journal article
EID:

2-s2.0-85062930710

Contributors: Morris, M.J.; Hesson, L.B.; Poulos, R.C.; Ward, R.L.; Wong, J.W.H.; Youngson, N.A.
Source: Self-asserted source
Rebecca Poulos via Scopus - Elsevier

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations

PLOS Genetics
2018-11-09 | Journal article
Contributors: Rebecca C. Poulos; Erik Larsson; Yuen T. Wong; Regina Ryan; Herbert Pang; Jason W. H. Wong
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Disruption of a -35kb enhancer impairs CTCF binding and MLH1 expression in colorectal cells

Clinical Cancer Research
2018-06-13 | Journal article
Contributors: Qing Liu; Julie A Thoms; Andrea C Nunez; Yizhou Huang; Kathy Knezevic; Deborah Packham; Rebecca C. Poulos; Rachel Williams; Dominik Beck; Nicholas J. Hawkins et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

cis-Regulatory Driver Mutations in Cancer Genomes

eLS
2017 | Book chapter
Source: Self-asserted source
Rebecca Poulos

The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription

Cancer Research
2017 | Journal article
Source: Self-asserted source
Rebecca Poulos

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes

Nucleic Acids Research
2017 | Journal article
Source: Self-asserted source
Rebecca Poulos

Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples.

Oncotarget
2017-11 | Journal article
Contributors: Ma S; Menon R; Poulos RC; Wong JWH
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes.

Nucleic acids research
2017-07 | Journal article
Contributors: Poulos RC; Olivier J; Wong JWH
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.

Cancer research
2017-05 | Journal article
Contributors: Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D et al.
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes

Nature
2016 | Journal article
Source: Self-asserted source
Rebecca Poulos

Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif

Cell reports
2016 | Journal article
Source: Self-asserted source
Rebecca Poulos

Mutation hotspots in cis-regulatory regions in cancer

Oncoscience
2016 | Journal article
Source: Self-asserted source
Rebecca Poulos

Mutation hotspots in cis-regulatory regions in cancer.

Oncoscience
2016 | Journal article
Contributors: Poulos RC; Wong JW
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif.

Cell reports
2016-12 | Journal article
Contributors: Poulos RC; Thoms JAI; Guan YF; Unnikrishnan A; Pimanda JE; Wong JWH
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes.

Nature
2016-04 | Journal article
Contributors: Perera D; Poulos RC; Shah A; Beck D; Pimanda JE; Wong JW
Source: Self-asserted source
Rebecca Poulos via Europe PubMed Central
grade
Preferred source (of 2)‎

Systematic screening of promoter regions pinpoints functional cis-regulatory mutations in a cutaneous melanoma genome

Molecular Cancer Research
2015 | Journal article
Source: Self-asserted source
Rebecca Poulos

The search for cis-regulatory driver mutations in cancer genomes

Oncotarget
2015 | Journal article
Source: Self-asserted source
Rebecca Poulos
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