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Works (25)

ABO-A antibody induction in mice is T-cell-dependent, estrogen-independent, and modulated by CD22

American Journal of Transplantation
2025-03 | Journal article
DOI: 10.1016/j.ajt.2025.03.001
Contributors: Ibrahim Adam; Bruce Motyka; Jean Pearcey; Kesheng Tao; Peter J. Cowan; Lori J. West
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Crossref

Extending the in vivo persistence of synthetic glycoconjugates using a serum-protein binder

RSC Chemical Biology
2022 | Journal article
DOI: 10.1039/D2CB00126H
Contributors: Gour Chand Daskhan; Bruce Motyka; Roger Bascom; Hanh Thuc Tran; Kesheng Tao; Lori J. West; Christopher W. Cairo
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Crossref

ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2

Virulence
2022-12-31 | Journal article
DOI: 10.1080/21505594.2021.2019959
Contributors: Sergio Gil-Manso; Iria Miguens Blanco; Bruce Motyka; Anne Halpin; Rocío López-Esteban; Verónica Astrid Pérez-Fernández; Diego Carbonell; Luis Andrés López-Fernández; Lori West; Rafael Correa-Rocha et al.
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Crossref

A dendritic cell receptor-targeted chimeric immunotherapeutic protein (C-HBV) for the treatment of chronic hepatitis B

Human Vaccines & Immunotherapeutics
2020-04-02 | Journal article
DOI: 10.1080/21645515.2019.1689080
Contributors: Allan Ma; Bruce Motyka; Klaus Gutfreund; Yuenian Eric Shi; Rajan George
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Crossref

A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo

Human Vaccines & Immunotherapeutics
2020-04-02 | Journal article
DOI: 10.1080/21645515.2019.1689081
Contributors: Rajan George; Allan Ma; Bruce Motyka; Yuenian Eric Shi; Qiang Liu; Philip Griebel
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Crossref

Identification of cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) isoforms in the Pekin duck.

2010-07 | Journal article
DOI: 10.1016/j.dci.2010.02.004
PMID: 20156479
Contributors: Yao Q; Fischer KP; Motyka B; Ferland S; Li L; Tyrrell DL; Gutfreund KS
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Induction of human blood group a antigen expression on mouse cells, using lentiviral gene transduction.

2010-07 | Journal article
DOI: 10.1089/hum.2008.089
PMID: 20163247
PMC: PMC2938359
Contributors: Fan X; Lang H; Zhou X; Zhang L; Yin R; Maciejko J; Giannitsos V; Motyka B; Medin JA; Platt JL et al.
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes.

2008-03 | Journal article
DOI: 10.4049/jimmunol.180.6.3766
PMID: 18322182
Contributors: Hallermalm K; Seki K; De Geer A; Motyka B; Bleackley RC; Jager MJ; Froelich CJ; Kiessling R; Levitsky V; Levitskaya J
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Identification of a novel human granzyme B inhibitor secreted by cultured sertoli cells.

2006-10 | Journal article
DOI: 10.4049/jimmunol.177.8.5051
PMID: 17015688
Contributors: Sipione S; Simmen KC; Lord SJ; Motyka B; Ewen C; Shostak I; Rayat GR; Dufour JM; Korbutt GS; Rajotte RV et al.
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.

2006-02 | Journal article
DOI: 10.1091/mbc.E05-07-0631
PMID: 16280358
PMC: PMC1356574
Contributors: Veugelers K; Motyka B; Goping IS; Shostak I; Sawchuk T; Bleackley RC
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation.

2004-12 | Journal article
DOI: 10.1161/01.ATV.0000147162.51930.b7
PMID: 15472125
Contributors: Choy JC; Hung VH; Hunter AL; Cheung PK; Motyka B; Goping IS; Sawchuk T; Bleackley RC; Podor TJ; McManus BM et al.
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis.

2004-05 | Journal article
DOI: 10.1182/blood-2003-06-2156
PMID: 14739229
Contributors: Veugelers K; Motyka B; Frantz C; Shostak I; Sawchuk T; Bleackley RC
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

2000-10 | Journal article
DOI: 10.1016/S0092-8674(00)00140-9
PMID: 11081635
Contributors: Motyka B; Korbutt G; Pinkoski MJ; Heibein JA; Caputo A; Hobman M; Barry M; Shostak I; Sawchuk T; Holmes CF et al.
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent.

1999-11 | Journal article
PMID: 10528165
Contributors: Heibein JA; Barry M; Motyka B; Bleackley RC
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Functional similarity and differences between selection-independent CD4-CD8- alphabeta T cells and positively selected CD8 T cells expressing the same TCR and the induction of anergy in CD4-CD8- alphabeta T cells in antigen-expressing mice.

1999-08 | Journal article
PMID: 10415017
Contributors: Caveno J; Zhang Y; Motyka B; Teh SJ; Teh HS
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Naturally occurring low affinity peptide/MHC class I ligands can mediate negative selection and T cell activation.

1998-01 | Journal article
PMID: 9551958
Contributors: Motyka B; Teh HS
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Positive selection of thymocytes expressing the same TCR by different MHC ligands results in the production of functionally distinct thymocytes distinguished by differential expression of the heat stable antigen.

1998-01 | Journal article
PMID: 9551907
Contributors: Teh HS; Motyka B; Teh SJ
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Influence of the affinity of selecting ligands on T cell positive and negative selection and the functional maturity of the positively selected T cells.

1997 | Journal article
PMID: 9419427
Contributors: Teh HS; Motyka B; Teh SJ
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Fas (CD95)-independent regulation of immune responses by antigen-specific CD4-CD8+ T cells.

1996-05 | Journal article
DOI: 10.1093/intimm/8.5.675
PMID: 8671654
Contributors: Teh SJ; Dutz JP; Motyka B; Teh HS
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Apoptosis of ileal Peyer's patch B cells is increased by glucocorticoids or anti-immunoglobulin antibodies.

1995-07 | Journal article
DOI: 10.1002/eji.1830250711
PMID: 7621863
Contributors: Motyka B; Bhogal HS; Reynolds JD
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Rescue of ileal Peyer's patch B cells from apoptosis is associated with the induction of Bcl-2 expression.

1995-03 | Journal article
PMID: 7751020
Contributors: Motyka B; Reynolds JD
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Agents that activate protein kinase C rescue sheep ileal Peyer's patch B cells from apoptosis.

1993-06 | Journal article
DOI: 10.1002/eji.1830230619
PMID: 8500527
Contributors: Motyka B; Griebel PJ; Reynolds JD
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Apoptosis is associated with the extensive B cell death in the sheep ileal Peyer's patch and the chicken bursa of Fabricius: a possible role in B cell selection.

1991-08 | Journal article
DOI: 10.1002/eji.1830210825
PMID: 1868877
Contributors: Motyka B; Reynolds JD
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Chimeric antigen containing hepatitis c virus polypeptide and Fc fragment for eliciting an immune response

Patent
OTHER-ID:

CN101300355
Contributors: RAJAN GEORGE; LORNE TYRRELL; ANTOINE NOUJAIM; DAKAN WANG; ALLAN MA; BRUCE MOTYKA
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central

Chimeric hepatitis C virus antigens for eliciting an immune response

Patent
OTHER-ID:

ZA200804078
Contributors: RAJAN GEORGE; LORNE TYRRELL; ANTOINE NOUJAIM; DAKUN WANG; ALLAN MA; BRUCE MOTYKA
Source: Self-asserted source
Bruce Motyka via Europe PubMed Central
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