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computational biology, Boolean modeling, cancer cell biology, cellular aging, endothelial cell biology

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Employment (3)

The College of Wooster: Wooster, US

2021-08-01 to present | Withmore Williams Associate Professor (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Erzsébet Ravasz Regan

The College of Wooster: Wooster, OH, US

2015-08-01 to 2021-07-31 | Whitmore Williams Assistant Professor (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Erzsébet Ravasz Regan

Beth Israel Deaconess Medical Center : Boston, MA, US

2007-07-01 to 2015-07-31 | Instructor (Medicine)
Employment
Source: Self-asserted source
Erzsébet Ravasz Regan

Education and qualifications (4)

Beth Israel Deaconess Medical Center: Boston, MA, US

2016-11 to 2017-07 | Postdoctoral Fellow in Biology (Medicine)
Education
Source: Self-asserted source
Erzsébet Ravasz Regan

Los Alamos National Laboratory: Los Alamos, NM, US

2014-10 to 2016-09 | Director Funded Postdoctoral Fellow in Physics (Center for Nonlinear Studies)
Education
Source: Self-asserted source
Erzsébet Ravasz Regan

University of Notre Dame: Notre Dame, IN, US

2000-08 to 2014-09 | Ph. D. (Physics)
Education
Source: Self-asserted source
Erzsébet Ravasz Regan

Babeș-Bolyai University: Cluj-Napoca, Cluj, RO

1995-09 to 2000-06 | B. S. & M. S (Physics)
Education
Source: Self-asserted source
Erzsébet Ravasz Regan

Funding (1)

Mechanisms of Mosaic Heterogeneity in Endothelium

2015-07-01 to 2019-04-30 | Grant
National Heart, Lung, and Blood Institute (Bethesda, US)
GRANT_NUMBER: 1R01HL119322-01A1
GRANT_NUMBER: 1R01HL119322-01A1
Source: Self-asserted source
Erzsébet Ravasz Regan via DimensionsWizard

Works (41)

A Boolean network model of hypoxia, mechanosensing and TGF-β signaling captures the role of phenotypic plasticity and mutations in tumor metastasis

2024-12-20 | Preprint
DOI: 10.1101/2024.12.20.629594
Contributors: Grant Greene; Ian Zonfa; Erzsébet Ravasz Regan
Source: check_circle
Crossref

Unlocking mitochondrial dysfunction-associated senescence (MiDAS) with NAD+ – A Boolean model of mitochondrial dynamics and cell cycle control

Translational Oncology
2024-11 | Journal article
DOI: 10.1016/j.tranon.2024.102084
Contributors: Herbert Sizek; Dávid Deritei; Katherine Fleig; Marlayna Harris; Peter L. Regan; Kimberly Glass; Erzsébet Ravasz Regan
Source: check_circle
Crossref

HHIP’s Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility

2024-09-09 | Preprint
DOI: 10.1101/2024.09.05.611545
Contributors: Dávid Deritei; Wardatul Jannat Anamika; Xiaobo Zhou; Edwin K. Silverman; Erzsébet Ravasz Regan; Kimberly Glass
Source: check_circle
Crossref

Unlocking Mitochondrial Dysfunction-Associated Senescence (MiDAS) with NAD+– a Boolean Model of Mitochondrial Dynamics and Cell Cycle Control

2023-12-18 | Preprint
DOI: 10.1101/2023.12.18.572194
Contributors: Herbert Sizek; Dávid Deritei; Katherine Fleig; Marlayna Harris; Peter L. Regan; Kimberly Glass; Erzsébet Ravasz Regan
Source: check_circle
Crossref

Boolean modeling of mechanosensitive Epithelial to Mesenchymal Transition and its reversal

2022-09-01 | Preprint
DOI: 10.1101/2022.08.29.505701
Contributors: Emmalee Sullivan; Marlayna Harris; Arnav Bhatnagar; Eric Guberman; Ian Zonfa; Erzsébet Ravasz Regan
Source: check_circle
Crossref

Stochastic phenotypic switching in endothelial cell heterogeneity

Phenotypic Switching
2020 | Book chapter
DOI: 10.1016/b978-0-12-817996-3.00004-9
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan

Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cellsin silicoandin vivo

2020-08-23 | Preprint
DOI: 10.1101/2020.08.22.261263
Contributors: Bahti Zakirov; Georgios Charalambous; Irene M. Aspalter; Kelvin Van-Vuuren; Thomas Mead; Kyle Harrington; Raphael Thuret; Erzsébet Ravasz Regan; Shane Paul Herbert; Katie Bentley
Source: check_circle
Crossref

Boolean model of anchorage dependence and contact inhibition points to coordinated inhibition but semi-independent induction of proliferation and migration.

Computational and structural biotechnology journal
2020-08-04 | Journal article
DOI: 10.1016/j.csbj.2020.07.016
PMID: 32913583
PMC: PMC7451872
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan

A feedback loop of conditionally stable circuits drives the cell cycle from checkpoint to checkpoint

Scientific Reports
2019-11-11 | Journal article
DOI: 10.1038/s41598-019-52725-1
Contributors: Dávid Deritei; Jordan Rozum; Erzsébet Ravasz Regan; Réka Albert
Source: check_circle
Crossref

Boolean model of growth signaling, cell cycle and apoptosis predicts the molecular mechanism of aberrant cell cycle progression driven by hyperactive PI3K

PLOS Computational Biology
2019-03-15 | Journal article
DOI: 10.1371/journal.pcbi.1006402
Contributors: Herbert Sizek; Jeffrey J. Saucerman; Andrew Hamel; Dávid Deritei; Sarah Campbell; Erzsébet Ravasz Regan
Source: check_circle
Crossref

Combined Toxicity of Insecticides and Fungicides Applied to California Almond Orchards to Honey Bee Larvae and Adults

Insects
2019-01 | Journal article | Author
DOI: 10.3390/insects10010020
Contributors: Andrea Wade; Chia-Hua Lin; Colin Kurkul; Erzsébet Ravasz Regan; Reed M. Johnson
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Time to Decide? Dynamical Analysis Predicts Partial Tip/Stalk Patterning States Arise during Angiogenesis

PLOS ONE
2016-11 | Journal article
DOI: 10.1371/journal.pone.0166489
Part of ISSN: 1932-6203
Contributors: Lakshmi Venkatraman; Erzsébet Ravasz Regan; Katie Bentley; Domenico Ribatti
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin

The Journal of Immunology
2016-04 | Journal article
DOI: 10.4049/jimmunol.1501819
Part of ISSN: 0022-1767
Contributors: Jill Moser; Peter Heeringa; Rianne M. Jongman; Peter J. Zwiers; Anita E. Niemarkt; Rui Yan; Inge A. de Graaf; Ranran Li; Erzsébet Ravasz Regan; Philipp Kümpers et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Principles of dynamical modularity in biological regulatory networks

Scientific Reports
2016-03 | Journal article
DOI: 10.1038/srep21957
Part of ISSN: 2045-2322
Contributors: Dávid Deritei; William C. Aird; Mária Ercsey-Ravasz; Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

Nature Communications
2016-01-08 | Journal article
DOI: 10.1038/ncomms10160
Part of ISSN: 2041-1723
Contributors: Lei Yuan; Gary C. Chan; David Beeler; Lauren Janes; Katherine C. Spokes; Harita Dharaneeswaran; Anahita Mojiri; William J. Adams; Tracey Sciuto; Guillermo Garcia-Cardeña et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Expression of the Robo4 receptor in endothelial cells is regulated by two AP-1 protein complexes

Biochemical and Biophysical Research Communications
2015-11 | Journal article
DOI: 10.1016/j.bbrc.2015.10.029
Part of ISSN: 0006-291X
Contributors: Yoshiaki Okada; Hiroki Naruse; Toru Tanaka; Nobuaki Funahashi; Erzsébet Ravasz Regan; Kazuma Yamakawa; Nobumasa Hino; Kenji Ishimoto; Takefumi Doi; William C. Aird
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer

Cancer Research
2014-10 | Journal article
DOI: 10.1158/0008-5472.can-14-1490
Part of ISSN: 0008-5472
Contributors: C. Priolo; S. Pyne; J. Rose; E. R. Regan; G. Zadra; C. Photopoulos; S. Cacciatore; D. Schultz; N. Scaglia; J. McDunn et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Can Active Perception Generate Bistability? Heterogeneous Collective Dynamics and Vascular Patterning

Artificial Life 14: Proceedings of the Fourteenth International Conference on the Synthesis and Simulation of Living Systems
2014-07 | Conference paper
DOI: 10.7551/978-0-262-32621-6-ch053
Contributors: Katie Bentley; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston MA; Kyle Harrington; Erzsébet Regan
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Community detection by graph Voronoi diagrams

New J. Phys.
2014-06-01 | Journal article
DOI: 10.1088/1367-2630/16/6/063007
Contributors: Dávid Deritei; Zsolt I Lázár; István Papp; Ferenc Járai-Szabó; Róbert Sumi; Levente Varga; Erzsébet Ravasz Regan; Mária Ercsey-Ravasz
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

FOXO1-Mediated Activation of Akt Plays a Critical Role in Vascular Homeostasis

Circulation Research
2014-05 | Journal article
DOI: 10.1161/circresaha.115.303227
Part of ISSN: 0009-7330
Contributors: H. Dharaneeswaran; M. R. Abid; L. Yuan; D. Dupuis; D. Beeler; K. C. Spokes; L. Janes; T. Sciuto; P. M. Kang; S.-C. S. Jaminet et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Do Endothelial Cells Dream of Eclectic Shape?

Developmental Cell
2014-04 | Journal article
DOI: 10.1016/j.devcel.2014.03.019
Contributors: Katie Bentley; Andrew Philippides; Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

The flow dependency of Tie2 expression in endotoxemia

Intensive Care Med
2013-04-06 | Journal article
DOI: 10.1007/s00134-013-2899-7
Contributors: Neng F. Kurniati; Rianne M. Jongman; Franziska vom Hagen; Katherine C. Spokes; Jill Moser; Erzsébet Ravasz Regan; Guido Krenning; Jan-Renier A. J. Moonen; Martin C. Harmsen; Michel M. R. F. Struys et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Dynamical Systems Approach to Endothelial Heterogeneity

Circulation Research
2012-06 | Journal article
DOI: 10.1161/circresaha.111.261701
Part of ISSN: 0009-7330
Contributors: E. R. Regan; W. C. Aird
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle

Blood
2010-10 | Journal article
DOI: 10.1182/blood-2010-06-287987
Part of ISSN: 0006-4971
Contributors: J. Liu; L. Yuan; G. Molema; E. Regan; L. Janes; D. Beeler; K. C. Spokes; Y. Okada; T. Minami; P. Oettgen et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Detecting Hierarchical Modularity in Biological Networks

Computational Systems Biology
2009 | Other
DOI: 10.1007/978-1-59745-243-4_7
Contributors: Erzsébet Ravasz
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Hierarchical modularity in biological networks: the case of metabolic networks

Networks in Cell Biology
2009 | Other
DOI: 10.1017/cbo9780511845086.008
Contributors: Erzsébet Ravasz Regan; Mark Buchanan; Guido Caldarelli; Paolo De Los Rios; Francesco Rao; Michele Vendruscolo
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Networks: Structure and Dynamics

Encyclopedia of Complexity and Systems Science
2009 | Book chapter | Writing - original draft, Writing - review & editing
DOI: 10.1007/978-0-387-30440-3_356
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan
grade
Preferred source (of 2)‎

Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo

Blood
2009-10 | Journal article
DOI: 10.1182/blood-2009-05-220434
Part of ISSN: 0006-4971
Contributors: E. Jin; J. Liu; J.-i. Suehiro; L. Yuan; Y. Okada; V. Nikolova-Krstevski; K. Yano; L. Janes; D. Beeler; K. C. Spokes et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Network Structure of Protein Folding Pathways

2007 | Other
Source: Self-asserted source
Erzsébet Ravasz Regan

Hierarchical Organization of Modularity in Complex Networks

Statistical Mechanics of Complex Networks
2003 | Book chapter
DOI: 10.1007/978-3-540-44943-0_4
Part of ISBN: 9783540403722
Part of ISBN: 9783540449430
Part of ISSN: 0075-8450
Part of ISSN: 1616-6361
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan
grade
Preferred source (of 2)‎

Scale-Free and Hierarchical Structures in Complex Networks

AIP Conference Proceedings
2003 | Conference paper
DOI: 10.1063/1.1571285
Part of ISSN: 0094-243X
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan
grade
Preferred source (of 2)‎

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

Journal of Bacteriology
2003-09 | Journal article
DOI: 10.1128/jb.185.19.5673-5684.2003
Part of ISSN: 0021-9193
Contributors: S. Y. Gerdes; M. D. Scholle; J. W. Campbell; G. Balázsi; E. Ravasz; M. D. Daugherty; A. L. Somera; N. C. Kyrpides; I. Anderson; M. S. Gelfand et al.
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Hierarchical organization in complex networks

Phys. Rev. E
2003-02 | Journal article
DOI: 10.1103/physreve.67.026112
Contributors: Erzsébet Ravasz; Albert-László Barabási
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Networks in life: scaling properties and eigenvalue spectra

Physica A: Statistical Mechanics and its Applications
2002-11 | Journal article
DOI: 10.1016/s0378-4371(02)01181-0
Part of ISSN: 0378-4371
Contributors: I Farkas; I Derényi; H Jeong; Z Néda; Z.N Oltvai; E Ravasz; A Schubert; A.-L Barabási; T Vicsek
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Evolution of the social network of scientific collaborations

Physica A: Statistical Mechanics and its Applications
2002-08 | Journal article
DOI: 10.1016/s0378-4371(02)00736-7
Part of ISSN: 0378-4371
Contributors: A.L Barabási; H Jeong; Z Néda; E Ravasz; A Schubert; T Vicsek
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Hierarchical Organization of Modularity in Metabolic Networks

Science
2002-08 | Journal article
DOI: 10.1126/science.1073374
Contributors: E. Ravasz
Source: Self-asserted source
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Deterministic scale-free networks

Physica A: Statistical Mechanics and its Applications
2001-10 | Journal article
DOI: 10.1016/s0378-4371(01)00369-7
Contributors: Albert-László Barabási; Erzsébet Ravasz; Tamás Vicsek
Source: Self-asserted source
Erzsébet Ravasz Regan via Crossref Metadata Search

Physics of the rhythmic applause

Phys. Rev. E
2000-06 | Journal article
DOI: 10.1103/physreve.61.6987
Contributors: Z. Néda; E. Ravasz; T. Vicsek; Y. Brechet; A. L. Barabási
Source: Self-asserted source
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The sound of many hands clapping

Nature
2000-02 | Journal article
DOI: 10.1038/35002660
Part of ISSN: 0028-0836
Contributors: Z. Néda; E. Ravasz; Y. Brechet; T. Vicsek; A.-L. Barabási
Source: Self-asserted source
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Spatial stochastic resonance in one-dimensional Ising systems

Physical Review E
1999-10-01 | Journal article
DOI: 10.1103/physreve.60.r3463
Part of ISSN: 1063-651X
Contributors: Zoltán Néda; Árpád Rusz; Erzsébet Ravasz; Porus Lakdawala; Parshant M. Gade
Source: Self-asserted source
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The Architecture of Biological Networks

Topics in Biomedical Engineering International Book Series
Book chapter
DOI: 10.1007/978-0-387-33532-2_5
Part of ISBN: 9780387302416
Contributors: Erzsébet Ravasz Regan
Source: Self-asserted source
Erzsébet Ravasz Regan
grade
Preferred source (of 2)‎

Peer review (5 reviews for 3 publications/grants)

Review activity for iScience. (2)
Review activity for npj systems biology and applications. (1)
Review activity for PLoS computational biology. (2)
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