Personal information

Activities

Employment (3)

Massachusetts General Hospital: Boston, US

2021-04 to present | Research Fellow (Neurology)
Employment
Source: Self-asserted source
Orla Bonnar

Harvard University: Cambridge, US

2021-04 to present | Research Fellow (Harvard Medical School)
Employment
Source: Self-asserted source
Orla Bonnar

University of Sussex: Brighton, GB

2016 to 2021 | PhD Student (Sussex Neuroscience)
Employment
Source: Self-asserted source
Orla Bonnar

Funding (1)

Perivascular Clearance as a therapeutic target in Cerebral Amyloid Angiopathy

2024-01-01 to 2025-12-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

24POST1187589

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ProposalCentral

Works (10)

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice

Communications Biology
2025-01-29 | Journal article
Part of ISSN: 2399-3642
Contributors: Silvia Anderle; Orla Bonnar; Joseph Henderson; Kira Shaw; André Maia Chagas; Letitia McMullan; Alexandra Webber; Kirsty McGowan; Sarah L. King; Catherine Hall
Source: Self-asserted source
Orla Bonnar

Capillary regression leads to sustained local hypoperfusion by inducing constriction of upstream transitional vessels

Proceedings of the National Academy of Sciences
2024-09-10 | Journal article
Contributors: Stephanie K. Bonney; Cara D. Nielson; Maria J. Sosa; Orla Bonnar; Andy Y. Shih
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Crossref

APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice

Journal of Cerebral Blood Flow & Metabolism
2023-11 | Journal article
Contributors: Orla Bonnar; Kira Shaw; Silvia Anderle; Dori M Grijseels; Devin Clarke; Laura Bell; Sarah L King; Catherine N Hall
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Crossref

Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity

Journal of Cerebral Blood Flow & Metabolism
2023-10 | Journal article
Contributors: Leon P Munting; Orla Bonnar; Mariel G Kozberg; Corinne A Auger; Lydiane Hirschler; Steven S Hou; Steven M Greenberg; Brian J Bacskai; Susanne J van Veluw
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Crossref

A multi‐hit hypothesis for an APOE4‐dependent pathophysiological state

European Journal of Neuroscience
2022-11 | Journal article
Contributors: Oliver George Steele; Alexander Cameron Stuart; Lucy Minkley; Kira Shaw; Orla Bonnar; Silvia Anderle; Andrew Charles Penn; Jennifer Rusted; Louise Serpell; Catherine Hall et al.
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Crossref

Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages.

Acta neuropathologica communications
2022-05-09 | Journal article
Source: Self-asserted source
Orla Bonnar

Gradual Not Sudden Change: Multiple Sites of Functional Transition Across the Microvascular Bed

Frontiers in Aging Neuroscience
2022-02-14 | Journal article
Part of ISSN: 1663-4365
Source: Self-asserted source
Orla Bonnar

Publisher Correction: Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences

Nature Communications
2021-07-19 | Journal article
Contributors: K. Shaw; L. Bell; K. Boyd; D. M. Grijseels; D. Clarke; O. Bonnar; H. S. Crombag; C. N. Hall
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Crossref

Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences

Nature Communications
2021-05-27 | Journal article
Contributors: K. Shaw; L. Bell; K. Boyd; D. M. Grijseels; D. Clarke; O. Bonnar; H. S. Crombag; C. N. Hall
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Crossref

First, tau causes NO problem

Nature Neuroscience
2020-09-10 | Journal article
Contributors: Orla Bonnar; Catherine N. Hall
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Crossref