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Molecular Biology, Cancer Biology, Radiation Biology, Science Education, Cancer Stem Cells, Radio-resistance, Hypoxic Environment, DNA Repair / DNA Damage Response, Signal Transduction
Japan

Biography

[Collaboration Opportunities]

■ Automated quantification of cellular signals, such as DNA double-strand break markers (e.g., γ-H2AX and 53BP1 foci), is available.
If you are interested in Foci quantification, please contact me!

Reference: http://www.nature.com/articles/ncomms12808, Fig. 5
e-mail: t.hashimoto@tohoku.ac.jp
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■April 2023 – Present
Lecturer (Full-time, Senior Assistant Professor), Laboratory for Radiation Biology, Graduate School of Medicine, Tohoku University

■November 2022 – Present
Committee Member (Concurrent Position), Environmental Survey and Measurement Technology Committee, Onagawa Nuclear Power Plant (Expert Member, Appointed by Miyagi Prefecture)

・November 2017 – March 2023
Assistant Professor, Laboratory for Radiation Biology, Graduate School of Medicine, Tohoku University

・April 2022 – September 2022
Part-time Lecturer (Concurrent Position), Department of Biological Sciences, Graduate School of Science, The University of Tokyo.

・October 2016 – June 2017
Research Associate, Laboratory for Radiation Biology, Graduate School of Medicine, Tohoku University

・May 2016 – September 2016
Project Researcher, Department of Biological Sciences, Graduate School of Science, The University of Tokyo.

・April 2013 – March 2016
JSPS Research Fellow (DC1), Japan Society for the Promotion of Science (JSPS) (The University of Tokyo)

See also https://researchmap.jp/t.hashimoto

Activities

Employment (1)

Tohoku University: Aoba-ku, Sendai, Miyagi, JP

2016-10-01 to present | Lecturer (full time, Senior Assistant Professor) ( Laboratory for Radiation Biology, School of Medicine, Tohoku University)
Employment
Source: Self-asserted source
Takuma Hashimoto

Education and qualifications (5)

The University of Tokyo: Tokyo, JP

( PhD (Graduate School of Science))
Education
Source: Self-asserted source
Takuma Hashimoto

Ministry of Education, Culture, Sports, Science and Technology: Tokyo, JP

(Class 1 Radiation Protection Supervisor (National Certification))
Qualification
Source: Self-asserted source
Takuma Hashimoto

Ministry of Education, Culture, Sports, Science and Technology: Tokyo, JP

(Advanced Teaching License for High School (Science))
Qualification
Source: Self-asserted source
Takuma Hashimoto

Ministry of Education, Culture, Sports, Science and Technology: Tokyo, JP

(Advanced Teaching License for Junior High School (Science))
Qualification
Source: Self-asserted source
Takuma Hashimoto

Ministry of Education, Culture, Sports, Science and Technology: Tokyo, JP

(Standard Teaching License for Elementary School)
Qualification
Source: Self-asserted source
Takuma Hashimoto

Professional activities (7)

The Japanese Society for Radiation Research: -, JP

Outstanding Poster Award (56th Annual Meeting)
Distinction
Source: Self-asserted source
Takuma Hashimoto

Onagawa Nuclear Power Plant: Onagawa, Miyagi, JP

Committee Member (Environmental Survey and Measurement Technology Committee)
Invited position
Source: Self-asserted source
Takuma Hashimoto

Tohoku University: Sendai, JP

2019 | Outstanding Presentation Award, 10th Basic Medical Training Presentation ( School of Medicine)
Distinction
Source: Self-asserted source
Takuma Hashimoto

Zoological Society of Japan: -, JP

2014 | Best Presentation Award for Young Researchers (Kanto Branch)
Distinction
Source: Self-asserted source
Takuma Hashimoto

The University of Tokyo: Tokyo, JP

2014 | Outstanding Presentation Award (14th Life Science Symposium)
Distinction
Source: Self-asserted source
Takuma Hashimoto

Japan Student Services Organization: Yokohama, JP

2013 | Exemption from Repayment
Distinction
Source: Self-asserted source
Takuma Hashimoto

The Society for Extremophiles: -, JP

2011 | Outstanding Poster Award (12th Annual Meeting)
Distinction
Source: Self-asserted source
Takuma Hashimoto

Funding (5)

Grant-in-Aid for Scientific Research (B)

2020-04 to 2024-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (-, JP)
Source: Self-asserted source
Takuma Hashimoto

Grant-in-Aid for Early-Career Scientists

2019-04 to 2022-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (-, JP)
Source: Self-asserted source
Takuma Hashimoto

Grant-in-Aid for Research Activity Start-up

2017-08 to 2019-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (-, JP)
Source: Self-asserted source
Takuma Hashimoto

Grant-in-Aid for JSPS Fellows

2013-04 to 2016-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (-, JP)
Source: Self-asserted source
Takuma Hashimoto

Grant-in-Aid for Early-Career Scientists (DC1)

Grant
Ministry of Education, Culture, Sports, Science and Technology (-, JP)
Source: Self-asserted source
Takuma Hashimoto

Works (12)

AMPK/FOXO3a Pathway Increases Activity and/or Expression of ATM, DNA-PKcs, Src, EGFR, PDK1, and SOD2 and Induces Radioresistance under Nutrient Starvation

International Journal of Molecular Sciences
2023-08-15 | Journal article
Contributors: Yusuke Urushihara; Takuma Hashimoto; Yohei Fujishima; Yoshio Hosoi
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines

Biochemical and Biophysical Research Communications
2022-01 | Journal article
Part of ISSN: 0006-291X
Source: Self-asserted source
Takuma Hashimoto

DNA-PKcs is activated under nutrient starvation and activates Akt, MST1, FoxO3a, and NDR1

Biochemical and Biophysical Research Communications
2020-01 | Journal article
Contributors: Soichiro Shiga; Yasuhiko Murata; Takuma Hashimoto; Yusuke Urushihara; Yohei Fujishima; Kanna Kudo; Yaoki Sonohara; Miku Kurusu; Kazuya Takeda; Keiichi Jingu et al.
Source: check_circle
Crossref

Severe hypoxia increases expression of ATM and DNA-PKcs and it increases their activities through Src and AMPK signaling pathways

Biochemical and Biophysical Research Communications
2018-10 | Journal article
Part of ISSN: 0006-291X
Source: Self-asserted source
Takuma Hashimoto

Knockdown of AMPKα decreases ATM expression and increases radiosensitivity under hypoxia and nutrient starvation in an SV40-transformed human fibroblast cell line, LM217

Biochemical and Biophysical Research Communications
2018-01 | Journal article
Contributors: Yasuhiko Murata; Takuma Hashimoto; Yusuke Urushihara; Soichiro Shiga; Kazuya Takeda; Keiichi Jingu; Yoshio Hosoi
Source: check_circle
Crossref

DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades

Life
2017-06 | Journal article
Contributors: Takuma Hashimoto; Takekazu Kunieda
Source: Self-asserted source
Takuma Hashimoto via Crossref Metadata Search

Novel protein in tardigrade, Ramazzottius varieornatus, improves radio-tolerance of human cultured cells.

Radiation biology research communications
2017-03 | Journal issue or edition
Source: Self-asserted source
Takuma Hashimoto

Demystifying the resilience of water bears.

UTokyo Research
2016 | Website
Source: Self-asserted source
Takuma Hashimoto

クマムシの強さの謎を解く. クマムシ由来のタンパク質が放射線ダメージを防ぐ

東京大学ARTICLES
2016 | Website
Source: Self-asserted source
Takuma Hashimoto

ヒト培養細胞の放射線耐性を向上させる新規タンパク質をクマムシのゲノムから発見

東京大学大学院理学系研究科・理学部 広報室
2016 | Website
Source: Self-asserted source
Takuma Hashimoto

Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein

Nature Communications
2016-09 | Journal article
Contributors: Takuma Hashimoto; Daiki D. Horikawa; Yuki Saito; Hirokazu Kuwahara; Hiroko Kozuka-Hata; Tadasu Shin-I; Yohei Minakuchi; Kazuko Ohishi; Ayuko Motoyama; Tomoyuki Aizu et al.
Source: Self-asserted source
Takuma Hashimoto via Crossref Metadata Search

Study on novel protein Dsup from an extremotolerant tardigrade,that improves radio-tolerance in human cultured cells

2016-09-05 | Journal issue or edition
Source: Self-asserted source
Takuma Hashimoto