Personal information

Biomedical imaging, Biomechanics, Optical imaging, Ophthalmology, Collagen
United States

Activities

Employment (4)

Massachusetts General Hospital: Boston, MA, US

2024-02-01 to present | Research Fellow (Wellman Center for Photomedicine)
Employment
Source: Self-asserted source
Po-Yi Lee

University of Pittsburgh: Pittsburgh, PA, US

2023-08-01 to 2024-01-31 | Postdoctoral Associate (Ophthalmology)
Employment
Source: Self-asserted source
Po-Yi Lee

Academia Sinica: Taipei, TW

2017-02 to 2018-07 | Research Assistant
Employment
Source: Self-asserted source
Po-Yi Lee

Lee and Li Attorneys-at-Law: Taipei, TW

2014-07 to 2014-08 | Patent Engineer (Intern)
Employment
Source: Self-asserted source
Po-Yi Lee

Education and qualifications (4)

University of Pittsburgh: Pittsburgh, PA, US

2018-08 to 2023-08 | Doctor of Philosophy (Bioengineering)
Education
Source: Self-asserted source
Po-Yi Lee

National Taiwan University: Taipei, TW

2014-09 to 2016-11 | Master of Science (Biomedical Electronics and Bioinformatics)
Education
Source: Self-asserted source
Po-Yi Lee

National Tsing Hua University: Hsinchu, TW

2010-09 to 2014-06 | Bachelor of Science (Biomedical Engineering and Environmental Sciences)
Education
Source: Self-asserted source
Po-Yi Lee

National Tsing Hua University: Hsinchu, TW

2010-09 to 2014-06 | Bachelor of Science (Electrical Engineering)
Education
Source: Self-asserted source
Po-Yi Lee

Professional activities (11)

Association for Research in Vision and Ophthalmology: Rockville, Maryland, US

2022 to present | Member
Membership
Source: Self-asserted source
Po-Yi Lee

International Society for Optics and Photonics: Bellingham, Washington, US

2019 to present | Member
Membership
Source: Self-asserted source
Po-Yi Lee

Association for Research in Vision and Ophthalmology: Rockville, Maryland, US

2023-10 | 1st Place - Scientific Image Contest
Distinction
Source: Self-asserted source
Po-Yi Lee

Boston Taiwanese Biotechnology Association: Boston, US

2023-07 | Oral Presentation Award
Distinction
Source: Self-asserted source
Po-Yi Lee

Summer Biomechanics, Bioengineering, and Biotransport Conference: Lake Geneva, Wisconsin, US

2023-06 | Second place - Cover Art Contest
Distinction
Source: Self-asserted source
Po-Yi Lee

World Congress of Biomechanics: Taipei, TW

2022-07 | Honorable Mention - Young Researcher (Pre-Doctoral) Award
Distinction
Source: Self-asserted source
Po-Yi Lee

American Society of Mechanical Engineers: New York, New York, US

2019 to 2022 | Member
Membership
Source: Self-asserted source
Po-Yi Lee

American Society of Mechanical Engineers: New York, New York, US

2021-06 | 1st Place - Bioengineering Division PhD-level Student Paper Competition
Distinction
Source: Self-asserted source
Po-Yi Lee

Ministry of Education: Taipei, TW

2021 | Government Scholarship to Study Abroad
Distinction
Source: Self-asserted source
Po-Yi Lee

Carnegie Mellon University: Pittsburgh, US

2018 | Outstanding Poster Award - Carnegie Mellon Forum on Biomedical Engineering
Distinction
Source: Self-asserted source
Po-Yi Lee

National Tsing Hua University: Hsinchu, TW

2012 | National Tsing Hua University Exchange Scholarship to Mainland China
Distinction
Source: Self-asserted source
Po-Yi Lee

Funding (1)

光聲血管照相機:用於皮下或末稍血管相關病變篩檢

2013 to 2014 | Grant
National Science Council (Taipei, TW)
Source: Self-asserted source
Po-Yi Lee

Works (27)

Direct measurements of collagen fiber recruitment in the posterior pole of the eye

Acta Biomaterialia
2024-01 | Journal article
Part of ISSN: 1742-7061
Contributors: Po-Yi Lee; Gosia Fryc; John Gnalian; Bingrui Wang; Yi Hua; Susannah Waxman; Fuqiang Zhong; Bin Yang; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

2D or not 2D? Mapping the in-depth inclination of the collagen fibers of the corneoscleral shell

Experimental Eye Research
2023-12 | Journal article
Part of ISSN: 0014-4835
Contributors: Fengting Ji; Marissa Quinn; Yi Hua; Po-Yi Lee; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Instant polarized light microscopy pi (IPOLπ) for quantitative imaging of collagen architecture and dynamics in ocular tissues

Optics and Lasers in Engineering
2023-07 | Journal article
Part of ISSN: 0143-8166
Contributors: Po-Yi Lee; Hannah Schilpp; Nathan Naylor; Simon C. Watkins; Bin Yang; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles

Journal of Biomechanical Engineering
2023-05-01 | Journal article
Part of ISSN: 0148-0731
Part of ISSN: 1528-8951
Contributors: Ning-Jiun Jan; Po-Yi Lee; Jacob Wallace; Michael Iasella; Alexandra Gogola; Bingrui Wang; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

High-resolution dual-modality imaging for collagen fibers and blood vessels in lamina cribrosa (LC) beams

Investigative Ophthalmology & Visual Science
2023-04 | Conference abstract
Contributors: Lee, Po-Yi; Waxman, Susannah; Schilpp, Hannah; Naylor, Nathan; Wallace, Callen; Watkins, Simon; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Moderately elevated IOP may alter optic nerve head hemodynamics enough to cause mild hypoxia over a substantial part of the lamina cribrosa

Investigative Ophthalmology & Visual Science
2023-04 | Conference abstract
Contributors: Lu, Yuankai; Hua, Yi; Wang, Bingrui; Zhong, Fuqiang; Theophanous, Andrew; Tahir, Shaharoz; Lee, Po-Yi; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

More peripapillary sclera (PPS) collagen fibers straighten than lamina cribrosa (LC) fibers before reaching 10% bundle stretch

Investigative Ophthalmology & Visual Science
2023-04 | Conference abstract
Contributors: Lee, Po-Yi; Fryc, Gosia; Gnalian, John; Hua, Yi; Waxman, Susannah; Zhong, Fuqiang; Yang, Bin; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Characterizing femtosecond laser effects on collagen (Conference Presentation)

Optical Elastography and Tissue Biomechanics X
2023-01 | Conference abstract
Contributors: Lee, Po-Yi; Lu, Yuankai; Quinn, Marissa; Waxman, Susannah; Ji, Fengting; Gibson, Gregory A; Yang, Bin; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

The lamina cribrosa vascular network is heavily interconnected with that of adjacent regions, not just the periphery, likely improving perfusion resilience

Investigative Ophthalmology & Visual Science
2022 | Conference abstract
Contributors: Sigal, Ian A; Lee, Po-Yi; Quinn, Marissa; Waxman, Susannah; Voorhees, Andrew P; Yang, Bin; Jakobs, Tatjana C; Rizzo, Joseph; Fortune, Brad; Hua, Yi
Source: Self-asserted source
Po-Yi Lee

Eye-specific 3D modeling of factors influencing oxygen concentration in the lamina cribrosa

Experimental Eye Research
2022-07 | Journal article
Part of ISSN: 0014-4835
Contributors: Yi Hua; Yuankai Lu; Jason Walker; Po-Yi Lee; Qi Tian; Haiden McDonald; Pedro Pallares; Fengting Ji; Bryn L. Brazile; Bin Yang et al.
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Real-time imaging of optic nerve head collagen microstructure and biomechanics using instant polarized light microscopy

Experimental Eye Research
2022-04 | Journal article | Author
Part of ISSN: 0014-4835
Contributors: Po-Yi Lee; Bin Yang; Yi Hua; Susannah Waxman; Ziyi Zhu; Fengting Ji; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 3)‎

A Workflow for 3D Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network

Journal of Biomechanical Engineering
2022-03-10 | Journal article
Part of ISSN: 0148-0731
Part of ISSN: 1528-8951
Contributors: Po-Yi Lee; Yi Hua; Bryn Brazile; Bin Yang; Lin Wang; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Lamina cribrosa vessel and collagen beam networks are distinct

Experimental Eye Research
2022-02 | Journal article
Part of ISSN: 0014-4835
Contributors: Susannah Waxman; Bryn L. Brazile; Bin Yang; Po-Yi Lee; Yi Hua; Alexandra Gogola; Po Lam; Andrew P. Voorhees; Joseph F. Rizzo; Tatjana C. Jakobs et al.
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 3)‎

3D eye-specific analysis of factors influencing lamina cribrosa oxygen concentration

Investigative Ophthalmology & Visual Science
2021 | Conference abstract
Contributors: Hua, Yi; Walker, Jason Arthur; Lee, Po-Yi; Brazile, Bryn; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Real-time structured polarized light imaging of dynamics of thick collagenous tissues

Emerging Digital Micromirror Device Based Systems and Applications XIII
2021-03-05 | Conference paper
Contributors: Grace Ingram; Po-Yi Lee; Benjamin Bernarding; Ian A. Sigal; Bin Yang
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Instant polarized light microscopy for imaging collagen microarchitecture and dynamics

Journal of Biophotonics
2021-02 | Journal article
Part of ISSN: 1864-063X
Part of ISSN: 1864-0648
Contributors: Bin Yang; Po‐Yi Lee; Yi Hua; Bryn Brazile; Susannah Waxman; Fengting Ji; Ziyi Zhu; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Characterization of lamina cribrosa beam insertion into the sclera canal in sheep, pig, monkey, and human

Investigative Ophthalmology & Visual Science
2020 | Conference abstract
Contributors: Ji, Fengting; Yang, Bin; Hua, Yi; Lee, Po-Yi; Zhu, Ziyi; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Microstructural evidence that lamina cribrosa beams (LC), peripapillary sclera (PPS) and central retinal artery (CRA) have distinct mechanical behaviors when stretched

Investigative Ophthalmology & Visual Science
2020 | Conference abstract
Contributors: Lee, Po-Yi; Yang, Bin; Zhu, Ziyi; Ji, Fengting; Hua, Yi; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Real-time structured polarized light imaging (rtSPLI) for thick ocular tissue dynamics

Investigative Ophthalmology & Visual Science
2020 | Conference abstract
Contributors: Yang, Bin; Lee, Po-Yi; Echard, Melissa; Zhu, Ziyi; Ji, Fengting; Bernarding, Benjamin; Sigal, Ian A
Source: Self-asserted source
Po-Yi Lee

Rapid high resolution 3D imaging of expanded biological specimens with lattice light sheet microscopy

Methods
2020-03 | Journal article
Part of ISSN: 1046-2023
Contributors: Yun-Chi Tsai; Wei-Chun Tang; Christine Siok Lan Low; Yen-Ting Liu; Jyun-Sian Wu; Po-Yi Lee; Lindsay Quinn Chen; Yi-Ling Lin; Pakorn Kanchanawong; Liang Gao et al.
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Instant polarized light microscopy for real-time wide-field visualization of collagen architecture

Label-free Biomedical Imaging and Sensing (LBIS) 2020
2020-02-20 | Conference paper
Contributors: Po-Yi Lee; Bin Yang; Yi Hua; Bryn Brazile; Fengting Ji; Ziyi Zhu; Gosia A. Fryc; Ian A. Sigal
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Collagen fiber interweaving strongly influences sclera stiffness, and likely plays a central role in globe mechanics

Investigative Ophthalmology & Visual Science
2019 | Conference abstract
Contributors: Sigal, Ian A; Wang, Bingrui; Yang, Bin; Lee, Po-Yi; Foong, Tian Yong; Brazile, Bryn; Hua, Yi
Source: Self-asserted source
Po-Yi Lee

Real-time measurement of collagen architecture and deformations at sub-micron resolution

Summer Biomechanics, Bioengineering, and Biotransport Conference
2019 | Conference paper
Contributors: Lee, PY; Yang, B; Sigal, IA
Source: Self-asserted source
Po-Yi Lee

Real-time measurement of lamina cribrosa and sclera collagen architecture and mechanics at sub-micron resolution

Investigative Ophthalmology & Visual Science
2019 | Conference abstract
Contributors: Sigal, Ian A; Lee, PoYi; Brazile, Bryn; Lam, Po; Zhu, Ziyi; Hua, Yi; Yang, Bin
Source: Self-asserted source
Po-Yi Lee

The Applications of Lattice Light-sheet Microscopy for Functional Volumetric Imaging of Hippocampal Neurons in a Three-Dimensional Culture System

Micromachines
2019-09-11 | Journal article
Part of ISSN: 2072-666X
Contributors: Chen; Liu; Lu; Lee; Tsai; Wu; Chen; Chen
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Aurora B functions at the apical surface after specialized cytokinesis during morphogenesis in C. elegans

Development
2019-01-01 | Journal article
Part of ISSN: 1477-9129
Part of ISSN: 0950-1991
Contributors: Xiaofei Bai; Michael Melesse; Christopher G. Sorensen Turpin; Dillon Sloan; Chin-Yi Chen; Wen-Cheng Wang; Po-Yi Lee; James R. Simmons; Benjamin Nebenfuehr; Diana Mitchell et al.
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎

Dual-wavelength optical-resolution photoacoustic microscopy for cells with gold nanoparticle bioconjugates in three-dimensional cultures

SPIE Proceedings
2016-03-15 | Conference paper
Part of ISSN: 0277-786X
Contributors: Po-Yi Lee; Wei-Wen Liu; Shu-Ching Chen; Pai-Chi Li
Source: Self-asserted source
Po-Yi Lee
grade
Preferred source (of 2)‎