Personal information

Verified email domains

Population Genetics. Genomics. Molecular Evolution. Computer Linguistics
Germany

Activities

Employment (1)

Universität zu Köln: Köln, Nordrhein-Westfalen, DE

Professor for Population Genetics and Bioinformatics (Institut für Genetik)
Employment
Source: Self-asserted source
Thomas Wiehe

Funding (10)

Evolutionary signatures in gene copy-number variation in Brassicaceae (B05)

2022-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 506117328
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Desert transcriptomics: assessing the genetic basis of adaptation to aridity in desert dwellers (B07*)

2020-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 444915207
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Earth-life evolution on short time scales (B06*)

2020-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 444915188
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Protist evolution at the dry limit (B03)

2016-01-01 to 2020-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 318086007
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

The molecular basis of phenotypic plasticity and genetic assimilation in rapidly evolving lineages of East African cichlid fishes

2015-01-01 to 2021-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 274606803
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Adaptive evolution of immune gene families: origin, diversification and diversity of the NLR genes in zebrafish

2015-01-01 to 2020-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 274528215
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Combinatoric and probabilistic properties regarding the topology of genealogical trees and application in population genetics

2012-01-01 to 2020-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 221524226
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

The evolution of natural variation and molecular innovations in social insects

2012-01-01 to 2014-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 215377040
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Ausbildungskonzept "An integrative concept for Teaching and Research in Evolutionary Biology (iEvol)"

2006-03-31 to 2009-03-31 | Grant
Volkswagen Foundation (Hanover, DE)
GRANT_NUMBER: 81911
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Evolutionary innovations - a case study on chromatin insulators (C04)

2006-01-01 to 2017-12-31 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 19658609
Source: Self-asserted source
Thomas Wiehe via DimensionsWizard

Works (50 of 65)

Items per page:
Page 1 of 2

Decay of the CTCF paralog BORIS in neognathous birds

2025-02-16 | Preprint
Contributors: Katja Palitzsch; Thomas Wiehe; Peter Heger
Source: check_circle
Crossref

Muller’s ratchet and gene duplication

2024-12-29 | Preprint
Contributors: Fabian Freund; Johannes Wirtz; Yichen Zheng; Yannick Schäfer; Thomas Wiehe
Source: check_circle
Crossref

Copy number variation and population-specific immune genes in the model vertebrate zebrafish

eLife
2024-06-04 | Journal article
Contributors: Yannick Schäfer; Katja Palitzsch; Maria Leptin; Andrew R Whiteley; Thomas Wiehe; Jaanus Suurväli
Source: check_circle
Crossref

The structured coalescent in the context of gene copy number variation

Theoretical Population Biology
2023-12 | Journal article
Contributors: Moritz Otto; Thomas Wiehe
Source: check_circle
Crossref

Genome-wide SNP data reveal recent population structure ofHuidobria fruticosa(Loasaceae), a paleo-endemic lineage from the Atacama Desert

2023-12-04 | Preprint
Contributors: Felix F. Merklinger; Yichen Zheng; Tim Böhnert; Federico Luebert; Dörte Harpke; Alexandra Stoll; Thomas Wiehe; Marcus Koch; Dietmar Quandt
Source: check_circle
Crossref

Copy number variation and population-specific immune genes in the model vertebrate zebrafish

2023-08-24 | Preprint
Contributors: Yannick Schäfer; Katja Palitzsch; Maria Leptin; Andrew R. Whiteley; Thomas Wiehe; Jaanus Suurväli
Source: check_circle
Crossref

Detecting adaptive changes in gene copy number distribution accompanying the human out-of-Africa expansion

2023-08-14 | Preprint
Contributors: Moritz Otto; Yichen Zheng; Paul Grablowitz; Thomas Wiehe
Source: check_circle
Crossref

Parthenogenomics: insights on mutation rates and nucleotide diversity in parthenogeneticPanagrolaimusnematodes

2022-09-17 | Preprint
Contributors: Laura I. Villegas; Luca Ferretti; Thomas Wiehe; Ann-Marie Waldvogel; Philipp H. Schiffer
Source: check_circle
Crossref

Recombination, selection, and the evolution of tandem gene arrays.

Genetics
2022-07-01 | Journal article | Author
Contributors: Moritz Otto; Yichen Zheng; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe
grade
Preferred source (of 2)‎

The genetic factors of bilaterian evolution

eLife
2020-07-16 | Journal article
Contributors: Peter Heger; Wen Zheng; Anna Rottmann; Kristen A Panfilio; Thomas Wiehe
Source: check_circle
Crossref

Measuring the external branches of a Kingman tree: A discrete approach.

Theoretical population biology
2020-05-30 | Journal article
Contributors: Disanto F; Wiehe T
Source: Self-asserted source
Thomas Wiehe

The Laboratory Domestication of Zebrafish: From Diverse Populations to Inbred Substrains.

Molecular biology and evolution
2020-04-01 | Journal article | Author
Contributors: Jaanus Suurväli; Andrew R. Whiteley; Zheng Y; Gharbi K; Maria Leptin; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe
grade
Preferred source (of 2)‎

Adaptation in structured populations and fuzzy boundaries between hard and soft sweeps

PLOS Computational Biology
2019-11-11 | Journal article
Contributors: Yichen Zheng; Torsten Günther; Thomas Wiehe
Source: check_circle
Crossref

Signatures of the Evolution of Parthenogenesis and Cryptobiosis in the Genomes of Panagrolaimid Nematodes.

iScience
2019-10-24 | Journal article
Contributors: Philipp Schiffer; Etienne Danchin; Burnell AM; Christopher J. Creevey; Wong S; Dix I; O'Mahony G; Culleton BA; Corinne Rancurel; Stier G et al.
Source: Self-asserted source
Thomas Wiehe

DNA sequence-dependent chromatin architecture and nuclear hubs formation.

Scientific reports
2019-10-10 | Journal article | Author
Contributors: Kamel Jabbari; Chakraborty M; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe
grade
Preferred source (of 2)‎

The Evolving Moran Genealogy.

Theoretical population biology
2019-07-19 | Journal article
Contributors: Wirtz J; Wiehe T
Source: Self-asserted source
Thomas Wiehe

A common genomic code for chromatin architecture and recombination landscape.

PloS one
2019-03-13 | Journal article
Contributors: Kamel Jabbari; Wirtz J; Rauscher M; Wiehe T
Source: Self-asserted source
Thomas Wiehe

The neutral frequency spectrum of linked sites

Theoretical Population Biology
2018-09 | Journal article
Contributors: Luca Ferretti; Alexander Klassmann; Emanuele Raineri; Sebastián E. Ramos-Onsins; Thomas Wiehe; Guillaume Achaz
Source: check_circle
Crossref

Topological linkage disequilibrium calculated from coalescent genealogies.

Theoretical population biology
2018-09-19 | Journal article | Author
Contributors: Wirtz J; Rauscher M; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe
grade
Preferred source (of 2)‎

The Diverging Routes of BORIS and CTCF: An Interactomic and Phylogenomic Analysis

Life
2018-01 | Journal article
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Detecting Recent Positive Selection with a Single Locus Test Bipartitioning the Coalescent Tree.

Genetics
2017-12-07 | Journal article
Contributors: Zongfeng Yang; Li J; Wiehe T; Haipeng Li
Source: Self-asserted source
Thomas Wiehe

Decomposing the Site Frequency Spectrum: The Impact of Tree Topology on Neutrality Tests.

Genetics
2017-07-05 | Journal article
Contributors: Luca Ferretti; Ledda A; Wiehe T; Achaz G; Sebastian Ernesto Ramos-Onsins
Source: Self-asserted source
Thomas Wiehe

Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins.

BMC genomics
2016-11-03 | Journal article
Contributors: Thomas; Lucia Vedder; Dowling D; Malte Petersen; Meusemann K; Alexander Donath; Peters RS; Lars Podsiadlowski; Mayer C; Liu S et al.
Source: Self-asserted source
Thomas Wiehe

Ultra Large Gene Families: A Matter of Adaptation or Genomic Parasites?

Life
2016-08 | Journal article
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Structure and evolutionary history of a large family of NLR proteins in the zebrafish

Open Biology
2016-04 | Journal article
Contributors: Kerstin Howe; Philipp H. Schiffer; Julia Zielinski; Thomas Wiehe; Gavin K. Laird; John C. Marioni; Onuralp Soylemez; Fyodor Kondrashov; Maria Leptin
Source: check_circle
Crossref

A catalogue of Bilaterian-specific genes – their function and expression profiles in early development

2016-03-19 | Preprint
Contributors: Andrea Krämer-Eis; Luca Ferretti; Philipp H. Schiffer; Peter Heger; Thomas Wiehe
Source: check_circle
Crossref

Demography-adjusted tests of neutrality based on genome-wide SNP data.

Theoretical population biology
2014-06-06 | Journal article
Contributors: Marina Rafajlović; Klassmann A; Anders Eriksson; Wiehe T; Bernhard Mehlig
Source: Self-asserted source
Thomas Wiehe

New tools in the box: an evolutionary synopsis of chromatin insulators.

Trends in genetics : TIG
2014-04-28 | Journal article
Contributors: Peter Heger; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Yule-generated trees constrained by node imbalance.

Mathematical biosciences
2013-08-30 | Journal article
Contributors: Disanto F; Schlizio A; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Successive gain of insulator proteins in arthropod evolution.

Evolution; international journal of organic evolution
2013-06-04 | Journal article
Contributors: Peter Heger; George R; Wiehe T
Source: Self-asserted source
Thomas Wiehe

The effect of single recombination events on coalescent tree height and shape.

PloS one
2013-04-08 | Journal article
Contributors: Luca Ferretti; Disanto F; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Exact enumeration of cherries and pitchforks in ranked trees under the coalescent model.

Mathematical biosciences
2013-02-06 | Journal article
Contributors: Disanto F; Wiehe T
Source: Self-asserted source
Thomas Wiehe

The chromatin insulator CTCF and the emergence of metazoan diversity.

Proceedings of the National Academy of Sciences of the United States of America
2012-10-08 | Journal article
Contributors: Peter Heger; Marin B; Bartkuhn M; Schierenberg E; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Successful target cell transduction of capsid-engineered rAAV vectors requires clathrin-dependent endocytosis.

Gene therapy
2011-06-09 | Journal article
Contributors: Uhrig S; Coutelle O; Wiehe T; Perabo L; Michael Hallek; Büning H
Source: Self-asserted source
Thomas Wiehe

Estimating mutation distances from unaligned genomes.

Journal of computational biology : a journal of computational molecular cell biology
2009-10-01 | Journal article
Contributors: Haubold B; Pfaffelhuber P; Domazet-Loso M; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Simulation of DNA sequence evolution under models of recent directional selection.

Briefings in bioinformatics
2008-12-24 | Journal article
Contributors: Kim Y; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Identification of selective sweeps in closely related populations of the house mouse based on microsatellite scans.

Genetics
2008-09-14 | Journal article
Contributors: Teschke M; Mukabayire O; Wiehe T; Diethard Tautz
Source: Self-asserted source
Thomas Wiehe

Second-order moments of segregating sites under variable population size.

Genetics
2008-08-20 | Journal article
Contributors: Zivković D; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Applying genetic programming to the prediction of alternative mRNA splice variants.

Genomics
2007-02-05 | Journal article
Contributors: Vukusic I; Grellscheid SN; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Self-alignments to detect mutually exclusive exon usage.

In silico biology
2007-01-01 | Journal article
Contributors: Stephan M; Möller F; Wiehe T; Kleffe J
Source: Self-asserted source
Thomas Wiehe

Introduction to computational biology

2006 | Book
ISBN:

978-3-7643-6700-8

Contributors: Bernhard Haubold; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe via Deutsche Nationalbibliothek (DNB)

How repetitive are genomes?

BMC bioinformatics
2006-12-22 | Journal article
Contributors: Bernhard Haubold; Thomas Wiehe
Source: Self-asserted source
Thomas Wiehe via Deutsche Nationalbibliothek (DNB)

Identification of selective sweeps using a dynamically adjusted number of linked microsatellites.

Genetics
2006-10-22 | Journal article
Contributors: Wiehe T; Nolte V; Zivkovic D; Schlötterer C
Source: Self-asserted source
Thomas Wiehe

Identifying cis-regulatory modules by combining comparative and compositional analysis of DNA.

Bioinformatics (Oxford, England)
2006-10-10 | Journal article
Contributors: Pierstorff N; Casey Bergman; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Genome comparison without alignment using shortest unique substrings.

BMC bioinformatics
2005-05-23 | Journal article
Contributors: Haubold B; Pierstorff N; Möller F; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Comparative genomics: methods and applications.

Die Naturwissenschaften
2004-06-25 | Journal article
Contributors: Haubold B; Wiehe T
Source: Self-asserted source
Thomas Wiehe

gff2aplot: Plotting sequence comparisons.

Bioinformatics (Oxford, England)
2003-12-01 | Journal article
Contributors: Abril JF; Guigó R; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Comparative gene prediction in human and mouse.

Genome research
2003-01-01 | Journal article
Contributors: Genis Parra; Pankaj Agarwal; Abril JF; Wiehe T; Fickett JW; Guigó R
Source: Self-asserted source
Thomas Wiehe
grade
Preferred source (of 2)‎

Recombination and gene conversion in a 170-kb genomic region of Arabidopsis thaliana.

Genetics
2002-07-01 | Journal article
Contributors: Haubold B; Kroymann J; Ratzka A; Mitchell-Olds T; Wiehe T
Source: Self-asserted source
Thomas Wiehe

Calculating the SNP-effective sample size from an alignment.

Bioinformatics (Oxford, England)
2002-01-01 | Journal article
Contributors: Haubold B; Wiehe T
Source: Self-asserted source
Thomas Wiehe
Items per page:
Page 1 of 2