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ResearcherID: O-6778-2018
Scopus Author ID: 57188996426

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Employment (1)

Hubei University: Wuhan, Hubei Province, CN

2016-07-01 to present | Associate Professor (School of Life Sciences)
Employment
Source: Self-asserted source
Linzhen Hu

Education and qualifications (1)

Union Hospital of Tongji Medical College of Huazhong University of Science and Technology: Wuhan, Hubei, CN

2013-09-01 to 2016-06-01 | Ph.D.
Education
Source: Self-asserted source
Linzhen Hu

Funding (1)

Studies on the alkaloids of secondary metabolites from Aspergillus ochraceus and the mechanism of anti-Parkinson's disease

Award
National Natural Science Foundation of China (Beijing, CN)
Source: Self-asserted source
Linzhen Hu

Works (28)

Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway

Bioorganic Chemistry
2024 | Journal article
DOI: 10.1016/j.bioorg.2023.106955
EID:

2-s2.0-85175580966

Part of ISSN: 10902120 00452068
Contributors: Tong, Z.; Kong, L.; Zhang, Y.; Hu, T.; Dai, R.; Wang, Y.; Ji, J.; Huang, Z.; Hu, L.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Granulathiazole A protects 6-OHDA-induced Parkinson's disease from ferroptosis via activating Nrf2/HO-1 pathway

Bioorganic Chemistry
2024 | Journal article
DOI: 10.1016/j.bioorg.2024.107399
EID:

2-s2.0-85191304204

Part of ISSN: 10902120 00452068
Contributors: Kong, L.; Wang, Y.; Tong, Z.; Dai, R.; Yusuf, A.; Du, L.; Liu, B.; Huang, Z.; Hu, L.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Chaetocochin J exhibits anti-hepatocellular carcinoma effect independent of hypoxia

Bioorganic Chemistry
2023 | Journal article
DOI: 10.1016/j.bioorg.2023.106701
EID:

2-s2.0-85163821645

Part of ISSN: 10902120 00452068
Contributors: Hu, P.; Hu, L.; Chen, Y.; Wang, F.; Xiao, Y.; Tong, Z.; Li, H.; Xiang, M.; Tong, Q.; Zhang, Y.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H<sub>2</sub>O<sub>2</sub> Insult SH-SY5Y Cells Targeting Keap1-Nrf2

Chinese Journal of Chemistry
2022 | Journal article
DOI: 10.1002/cjoc.202200008
EID:

2-s2.0-85126373311

Part of ISSN: 16147065 1001604X
Contributors: Hu, L.; Wang, Z.; Tong, Z.; Hu, P.; Kong, L.; Luo, M.; Li, X.-N.; Zhang, Y.; Huang, Z.; Zhang, Y.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1&ndash;Nrf2

Marine Drugs
2022-03 | Journal article | Author
DOI: 10.3390/md20030191
Contributors: Xueyang Xiao; Zhou Tong; Yuexing Zhang; Hui Zhou; Mengying Luo; Tianhui Hu; Ping Hu; Luqi Kong; Zeqin Liu; Chan Yu et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Identification of anti-Parkinson's Disease Lead Compounds from Aspergillus ochraceus Targeting Adenosin Receptors A<sub>2A</sub>

ChemistryOpen
2021 | Journal article
DOI: 10.1002/open.202100022
EID:

2-s2.0-85107927373

Part of ISSN: 21911363
Contributors: Hu, L.; Tian, S.; Wu, R.; Tong, Z.; Jiang, W.; Hu, P.; Xiao, X.; Zhang, X.; Zhou, H.; Tong, Q. et al.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

New Metabolites from <i>Aspergillus ochraceus</i> with Antioxidative Activity and Neuroprotective Potential on H<sub>2</sub>O<sub>2</sub> Insult SH-SY5Y Cells

Molecules
2021-12 | Journal article | Author
DOI: 10.3390/molecules27010052
Contributors: Zhou Tong; Xueyang Xiao; Yuanayuan Lu; Yuexing Zhang; Ping Hu; Wen Jiang; Hui Zhou; Shixiang Pan; Zhiyong Huang; Linzhen Hu
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Research progress on chemical constituents and pharmachological activities of Hypericum japonicum,地耳草化学成分及药理活性研究进展

Chinese Traditional and Herbal Drugs
2020 | Journal article
DOI: 10.7501/j.issn.0253-2670.2020.06.035
EID:

2-s2.0-85085132924

Part of ISSN: 02532670
Contributors: Zhang, X.-K.; Chen, Y.; Hu, L.-Z.; Zhang, Y.-H.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Correction: The absolute configurations of hyperilongenols A-C: Rare 12,13-: Seco-spirocyclic polycyclic polyprenylated acylphloroglucinols with enolizable β,β′-Tricarbonyl systems from Hypericum longistylum Oliv. (Organic Chemistry Frontiers (2019) DOI: 10.1039/c9qo00245f)

Organic Chemistry Frontiers
2019 | Journal article
DOI: 10.1039/c9qo90045d
EID:

2-s2.0-85065848686

Part of ISSN: 20524129 20524110
Contributors: Zhang, N.; Shi, Z.; Guo, Y.; Xie, S.; Qiao, Y.; Li, X.-N.; Xue, Y.; Luo, Z.; Zhu, H.; Chen, C. et al.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Studies on chemical constituents and bioactivities of alkaloids from zanthoxylum schinifolium,青花椒生物碱类化学成分及生物活性研究

Chinese Traditional and Herbal Drugs
2019 | Journal article
DOI: 10.7501/j.issn.0253-2670.2019.06.006
EID:

2-s2.0-85068956195

Part of ISSN: 02532670
Contributors: Wu, R.-R.; Tian, S.-Y.; Chen, Y.; Hu, L.-Z.; Zhang, Y.-H.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

The absolute configurations of hyperilongenols A-C: Rare 12,13-: Seco -spirocyclic polycyclic polyprenylated acylphloroglucinols with enolizable β,β′-tricarbonyl systems from Hypericum longistylum Oliv.

Organic Chemistry Frontiers
2019 | Journal article
DOI: 10.1039/c9qo00245f
EID:

2-s2.0-85064973715

Part of ISSN: 20524129 20524110
Contributors: Zhang, N.; Shi, Z.; Guo, Y.; Xie, S.; Qiao, Y.; Li, X.-N.; Xue, Y.; Luo, Z.; Zhu, H.; Chen, C. et al.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Discovery of acylphloroglucinol-based meroterpenoid enantiomers as KSHV inhibitors from: Hypericum japonicum

RSC Advances
2018 | Journal article
DOI: 10.1039/c8ra04073g
EID:

2-s2.0-85049870447

Part of ISSN: 20462069
Contributors: Hu, L.; Liu, Y.; Wang, Y.; Wang, Z.; Huang, J.; Xue, Y.; Liu, J.; Liu, Z.; Chen, Y.; Zhang, Y.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Three New Indole Diketopiperazine Alkaloids from Aspergillus ochraceus

Chemistry and Biodiversity
2018 | Journal article
DOI: 10.1002/cbdv.201700550
EID:

2-s2.0-85045759684

Part of ISSN: 16121880 16121872
Contributors: Wen, H.; Liu, X.; Zhang, Q.; Deng, Y.; Zang, Y.; Wang, J.; Liu, J.; Zhou, Q.; Hu, L.; Zhu, H. et al.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Discovery of acylphloroglucinol-based meroterpenoid enantiomers as KSHV inhibitors from Hypericum japonicum

RSC Advances
2018-07-02 | Journal article
Source: Self-asserted source
Linzhen Hu

Hyperjaponol H, A New Bioactive Filicinic Acid-Based Meroterpenoid from <em>Hypericum japonicum</em> Thunb. ex Murray

Molecules
2018-03 | Journal article | Author
DOI: 10.3390/molecules23030683
Contributors: Rongrong Wu; Zijun Le; Zhenzhen Wang; Shuying Tian; Yongbo Xue; Yong Chen; Linzhen Hu; Zhang Yonghui
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Hyperjaponol H, A New Bioactive Filicinic Acid-Based Meroterpenoid from Hypericum japonicum Thunb. ex Murray

Molecules
2018-03-18 | Journal article
Source: Self-asserted source
Linzhen Hu

Two new geranylphenylacetate glycosides from the barks of Cinnamomum cassia

Natural Product Research
2017 | Journal article
DOI: 10.1080/14786419.2017.1294175
EID:

2-s2.0-85014571986

Part of ISSN: 14786427 14786419
Contributors: Zeng, J.-F.; Zhu, H.-C.; Lu, J.-W.; Hu, L.-Z.; Song, J.-C.; Zhang, Y.-H.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii

Chinese Chemical Letters
2017 | Journal article
DOI: 10.1016/j.cclet.2017.03.024
EID:

2-s2.0-85017436630

Part of ISSN: 10018417
Contributors: Lu, Y.-Y.; Gong, X.-P.; Xue, Y.-B.; Zhu, H.-C.; Li, X.-N.; Hu, L.-Z.; Guan, J.-K.; Zhang, J.-W.; Du, G.; Zhang, Y.-H.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

(±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep27588
EID:

2-s2.0-84973931538

Part of ISSN: 20452322
Contributors: Hu, L.; Zhu, H.; Li, L.; Huang, J.; Sun, W.; Liu, J.; Li, H.; Luo, Z.; Wang, J.; Xue, Y. et al.
Source: Self-asserted source
Linzhen Hu via Scopus - Elsevier

(±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum

Scientific Reports
2016-06-08 | Journal article
Source: Self-asserted source
Linzhen Hu

(±)-Japonicols A–D, Acylphloroglucinol-Based Meroterpenoid Enantiomers with Anti-KSHV Activities fromHypericum japonicum

J. Nat. Prod.
2016-05 | Journal article
DOI: 10.1021/acs.jnatprod.5b01119
Contributors: Linzhen Hu; Yongbo Xue; Jinwen Zhang; Hucheng Zhu; Chunmei Chen; Xiao-Nian Li; Junjun Liu; Zhenzhen Wang; Yu Zhang; Yonghui Zhang
Source: Self-asserted source
Linzhen Hu via Crossref Metadata Search
grade
Preferred source (of 2)‎

Filicinic Acid Based Meroterpenoids with Anti-Epstein–Barr Virus Activities fromHypericum japonicum

Org. Lett.
2016-05-06 | Journal article
DOI: 10.1021/acs.orglett.6b00906
Contributors: Linzhen Hu; Yu Zhang; Hucheng Zhu; Junjun Liu; Hua Li; Xiao-Nian Li; Weiguang Sun; Junfen Zeng; Yongbo Xue; Yonghui Zhang
Source: Self-asserted source
Linzhen Hu via Crossref Metadata Search
grade
Preferred source (of 2)‎

Two New Bioactive α-Pyrones from <em>Hypericum japonicum</em>

Molecules
2016-04 | Journal article
DOI: 10.3390/molecules21040515
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

A New Megastigmane Sesquiterpenoid from <i>Zanthoxylum Schinifolium</i> Sieb. et Zucc

Molecules
2016-03 | Journal article
DOI: 10.3390/molecules21030383
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

The Absolute Configurations of Hyperilongenols A–C: Rare 12,13-Seco-Spirocyclic Polycyclic Polyprenylated Acylphloroglucinols with Enolizable β,β′-Tricarbonyl Systems from Hypericum longistylum Oliv.

Org. Chem. Front.
Journal article
Source: Self-asserted source
Linzhen Hu

Three New Indole Diketopiperazine Alkaloids from Aspergillus ochraceus

Chem. Biodivers.
Journal article
Source: Self-asserted source
Linzhen Hu

Two new geranylphenylacetate glycosides from the barks of Cinnamomum cassia

Nat. Prod. Res.
Journal article
Source: Self-asserted source
Linzhen Hu

Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii

Chinese Chem. Lett.
Journal article
Source: Self-asserted source
Linzhen Hu

Peer review (2 reviews for 1 publication/grant)

Review activity for Bioorganic chemistry. (2)
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