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Employment (3)

Weatherall Institute of Molecular Medicine: Oxford, Oxfordshire, GB

2017-06-21 to present | Computational biologist (MRC Molecular Haematology Unit )
Employment
Source: Self-asserted source
Supat Thongjuea

RIKEN: Yokohama, JP

2015-04-01 to 2017-04-30 | Research Scientist (RIKEN Center for Life Science Technologies)
Employment
Source: Self-asserted source
Supat Thongjuea

Weatherall Institute of Molecular Medicine: Oxford, Oxfordshire, GB

2013-05-01 to 2015-03-31 | Postdoc (MRC Molecular Hematology Unit)
Employment
Source: Self-asserted source
Supat Thongjuea

Education and qualifications (1)

University of Bergen: Bergen, Hordaland, NO

2010 to 2014 | PhD (Department of Molecular Biology)
Education
Source: Self-asserted source
Supat Thongjuea

Works (41)

Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology

2024-09-19 | Preprint
DOI: 10.1101/2024.09.16.612263
Contributors: Muhammad Hanifi; Perihan Seda Ates-Kalkan; Sean Wen; Mathieu Fischer; Amanda Kroesen; Zulin Yu; Matthew Wood; Supat Thongjuea; Adam Mead; Tudor Alexandru Fulga et al.
Source: check_circle
Crossref

Epigenetic programming defines haematopoietic stem cell fate restriction

Nature Cell Biology
2023-06 | Journal article
DOI: 10.1038/s41556-023-01137-5
Contributors: Yiran Meng; Joana Carrelha; Roy Drissen; Xiying Ren; Bowen Zhang; Adriana Gambardella; Simona Valletta; Supat Thongjuea; Sten Eirik Jacobsen; Claus Nerlov
Source: check_circle
Crossref

MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data

Nucleic Acids Research
2023-03-21 | Journal article
DOI: 10.1093/nar/gkac1260
Contributors: Wei Xiong Wen; Adam J Mead; Supat Thongjuea
Source: check_circle
Crossref

MARVEL: An integrated alternative splicing analysis platform for single-cell RNA sequencing data

2022-08-26 | Preprint
DOI: 10.1101/2022.08.25.505258
Contributors: Wei Xiong Wen; Adam J Mead; Supat Thongjuea
Source: check_circle
Crossref

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Nature Communications
2021-12-02 | Journal article
DOI: 10.1038/s41467-021-27140-8
Contributors: Wen Hao Neo; Yiran Meng; Alba Rodriguez-Meira; Muhammad Z. H. Fadlullah; Christopher A. G. Booth; Emanuele Azzoni; Supat Thongjuea; Marella F. T. R. de Bruijn; Sten Eirik W. Jacobsen; Adam J. Mead et al.
Source: check_circle
Crossref

Technological advances and computational approaches for alternative splicing analysis in single cells

Computational and Structural Biotechnology Journal
2020 | Journal article
DOI: 10.1016/j.csbj.2020.01.009
Part of ISSN: 2001-0370
Source: Self-asserted source
Supat Thongjuea

VALERIE: Visual-based inspection of alternative splicing events at single-cell resolution

PLOS Computational Biology
2020-09-08 | Journal article
DOI: 10.1371/journal.pcbi.1008195
Contributors: Wei Xiong Wen; Mihaela Pertea; Adam J. Mead; Supat Thongjuea
Source: check_circle
Crossref

Functional annotation of human long noncoding RNAs via molecular phenotyping.

Genome research
2020-07-27 | Journal article
DOI: 10.1101/gr.254219.119
PMID: 32718982
Source: Self-asserted source
Supat Thongjuea

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

Molecular Cell
2020-05 | Journal article
DOI: 10.1016/j.molcel.2020.04.008
Part of ISSN: 1097-2765
Source: Self-asserted source
Supat Thongjuea

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

Cancer Cell
2020-04 | Journal article
DOI: 10.1016/j.ccell.2020.03.022
Part of ISSN: 1535-6108
Source: Self-asserted source
Supat Thongjuea

Single-cell analysis of bone marrow–derived CD34+ cells from children with sickle cell disease and thalassemia

Blood
2019-12-05 | Journal article
DOI: 10.1182/blood.2019002301
Contributors: Peng Hua; Noemi Roy; Josu de la Fuente; Guanlin Wang; Supat Thongjuea; Kevin Clark; Anindita Roy; Bethan Psaila; Neil Ashley; Yvonne Harrington et al.
Source: check_circle
Crossref

Identification of two distinct pathways of human myelopoiesis

Science Immunology
2019-05-24 | Journal article
DOI: 10.1126/sciimmunol.aau7148
Contributors: Roy Drissen; Supat Thongjuea; Kim Theilgaard-Mönch; Claus Nerlov
Source: check_circle
Crossref

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.

Haematologica
2019-04-11 | Journal article
DOI: 10.3324/haematol.2018.205351
PMID: 30975913
Source: Self-asserted source
Supat Thongjuea

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.

Molecular cell
2019-02-12 | Journal article
DOI: 10.1016/j.molcel.2019.01.009
PMID: 30765193
PMC: PMC6436961
Source: Self-asserted source
Supat Thongjuea

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.

Nature communications
2018-12-18 | Journal article
DOI: 10.1038/s41467-018-07787-6
PMID: 30560907
PMC: PMC6299140
Source: Self-asserted source
Supat Thongjuea

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo.

Developmental cell
2018-12-01 | Journal article
DOI: 10.1016/j.devcel.2018.11.009
PMID: 30513303
PMC: PMC6286384
Source: Self-asserted source
Supat Thongjuea

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

The Journal of experimental medicine
2017-07 | Journal article
DOI: 10.1084/jem.20161418
PMID: 28637883
PMC: PMC5502426
Contributors: Mead AJ; Neo WH; Barkas N; Matsuoka S; Giustacchini A; Facchini R; Thongjuea S; Jamieson L; Booth CAG; Fordham N et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Nature medicine
2017-06 | Journal article
DOI: 10.1038/nm.4336
PMID: 28504724
Contributors: Giustacchini A; Thongjuea S; Barkas N; Woll PS; Povinelli BJ; Booth CAG; Sopp P; Norfo R; Rodriguez-Meira A; Ashley N et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Nature immunology
2016-12 | Journal article
DOI: 10.1038/ni.3576
PMID: 27695000
PMC: PMC5172420
Contributors: Luis TC; Luc S; Mizukami T; Boukarabila H; Thongjuea S; Woll PS; Azzoni E; Giustacchini A; Lutteropp M; Bouriez-Jones T et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Nature immunology
2016-06 | Journal article
DOI: 10.1038/ni.3412
PMID: 27043410
PMC: PMC4972405
Contributors: Drissen R; Buza-Vidas N; Woll P; Thongjuea S; Gambardella A; Giustacchini A; Mancini E; Zriwil A; Lutteropp M; Grover A et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Nature communications
2016-03 | Journal article
DOI: 10.1038/ncomms11075
PMID: 27009448
PMC: PMC4820843
Contributors: Grover A; Sanjuan-Pla A; Thongjuea S; Carrelha J; Giustacchini A; Gambardella A; Macaulay I; Mancini E; Luis TC; Mead A et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

Nature cell biology
2016-02 | Journal article
DOI: 10.1038/ncb3299
PMID: 26780297
PMC: PMC4972409
Contributors: Buono M; Facchini R; Matsuoka S; Thongjuea S; Waithe D; Luis TC; Giustacchini A; Besmer P; Mead AJ; Jacobsen SE et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

Nature communications
2015-11 | Journal article
DOI: 10.1038/ncomms9893
PMID: 26593974
PMC: PMC4673834
Contributors: Stadhouders R; Cico A; Stephen T; Thongjuea S; Kolovos P; Baymaz HI; Yu X; Demmers J; Bezstarosti K; Maas A et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Cancer cell
2014-06 | Journal article
DOI: 10.1016/j.ccr.2014.03.036
PMID: 24835589
Contributors: Woll PS; Kjällquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.

The Journal of clinical investigation
2014-04 | Journal article
DOI: 10.1172/jci71520
PMID: 24614105
PMC: PMC3973089
Contributors: Stadhouders R; Aktuna S; Thongjuea S; Aghajanirefah A; Pourfarzad F; van Ijcken W; Lenhard B; Rooks H; Best S; Menzel S et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Nature
2013-10 | Journal article
DOI: 10.1038/nature12495
PMID: 23934107
Contributors: Sanjuan-Pla A; Macaulay IC; Jensen CT; Woll PS; Luis TC; Mead A; Moore S; Carella C; Matsuoka S; Bouriez Jones T et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Locus-specific proteomics by TChP: targeted chromatin purification.

Cell reports
2013-08 | Journal article
DOI: 10.1016/j.celrep.2013.07.004
PMID: 23911284
Contributors: Pourfarzad F; Aghajanirefah A; de Boer E; Ten Have S; Bryn van Dijk T; Kheradmandkia S; Stadhouders R; Thongjuea S; Soler E; Gillemans N et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data.

Nucleic acids research
2013-07 | Journal article
DOI: 10.1093/nar/gkt373
PMID: 23671339
PMC: PMC3711450
Contributors: Thongjuea S; Stadhouders R; Grosveld FG; Soler E; Lenhard B
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

In vivo live imaging of RNA polymerase II transcription factories in primary cells.

Genes & development
2013-06 | Journal article
PMC: PMC3701197
Contributors: Ghamari A; van de Corput MPC; Thongjuea S; van Cappellen WA; van IJcken W; van Haren J; Soler E; Eick D; Lenhard B; Grosveld FG
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

In vivo live imaging of RNA polymerase II transcription factories in primary cells.

Genes & development
2013-05 | Journal article
PMC: PMC3672652
Contributors: Ghamari A; van de Corput MPC; Thongjuea S; van Cappellen WA; van IJcken W; van Haren J; Soler E; Eick D; Lenhard B; Grosveld FG
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Genome-wide analysis shows that Ldb1 controls essential hematopoietic genes/pathways in mouse early development and reveals novel players in hematopoiesis.

Blood
2013-04 | Journal article
DOI: 10.1182/blood-2012-11-467654
PMID: 23390196
Contributors: Mylona A; Andrieu-Soler C; Thongjuea S; Martella A; Soler E; Jorna R; Hou J; Kockx C; van Ijcken W; Lenhard B et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

In vivo live imaging of RNA polymerase II transcription factories in primary cells.

Genes & development
2013-04 | Journal article
DOI: 10.1101/gad.216200.113
PMID: 23592796
PMC: PMC3639417
Contributors: Ghamari A; van de Corput MP; Thongjuea S; van Cappellen WA; van Ijcken W; van Haren J; Soler E; Eick D; Lenhard B; Grosveld FG
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Genome-wide DNA methylation profiling of non-small cell lung carcinomas.

Epigenetics & chromatin
2012 | Journal article
DOI: 10.1186/1756-8935-5-9
PMID: 22726460
PMC: PMC3407794
Contributors: Carvalho RH; Haberle V; Hou J; van Gent T; Thongjuea S; van Ijcken W; Kockx C; Brouwer R; Rijkers E; Sieuwerts A et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

DNA-binding factor CTCF and long-range gene interactions in V(D)J recombination and oncogene activation.

Blood
2012-06 | Journal article
DOI: 10.1182/blood-2012-03-402586
PMID: 22538856
Contributors: Ribeiro de Almeida C; Stadhouders R; Thongjuea S; Soler E; Hendriks RW
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development.

The EMBO journal
2012-02 | Journal article
DOI: 10.1038/emboj.2011.450
PMID: 22157820
PMC: PMC3280550
Contributors: Stadhouders R; Thongjuea S; Andrieu-Soler C; Palstra RJ; Bryne JC; van den Heuvel A; Stevens M; de Boer E; Kockx C; van der Sloot A et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus.

Immunity
2011-10 | Journal article
DOI: 10.1016/j.immuni.2011.07.014
PMID: 22035845
Contributors: Ribeiro de Almeida C; Stadhouders R; de Bruijn MJ; Bergen IM; Thongjuea S; Lenhard B; van Ijcken W; Grosveld F; Galjart N; Soler E et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

A systems approach to analyze transcription factors in mammalian cells.

Methods (San Diego, Calif.)
2011-02 | Journal article
DOI: 10.1016/j.ymeth.2010.08.002
PMID: 20705139
Contributors: Soler E; Andrieu-Soler C; Boer Ed; Bryne JC; Thongjuea S; Rijkers E; Demmers J; van IJcken W; Grosveld F
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.

Genes & development
2010-02 | Journal article
DOI: 10.1101/gad.551810
PMID: 20123907
PMC: PMC2811829
Contributors: Soler E; Andrieu-Soler C; de Boer E; Bryne JC; Thongjuea S; Stadhouders R; Palstra RJ; Stevens M; Kockx C; van Ijcken W et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles.

Nucleic acids research
2010-01 | Journal article
DOI: 10.1093/nar/gkp950
PMID: 19906716
PMC: PMC2808906
Contributors: Portales-Casamar E; Thongjuea S; Kwon AT; Arenillas D; Zhao X; Valen E; Yusuf D; Lenhard B; Wasserman WW; Sandelin A
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

RiceGeneThresher: a web-based application for mining genes underlying QTL in rice genome.

Nucleic acids research
2009-01 | Journal article
DOI: 10.1093/nar/gkn638
PMID: 18820292
PMC: PMC2686607
Contributors: Thongjuea S; Ruanjaichon V; Bruskiewich R; Vanavichit A
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

The Generation Challenge Programme comparative plant stress-responsive gene catalogue.

Nucleic acids research
2008-01 | Journal article
DOI: 10.1093/nar/gkm798
PMID: 17933772
PMC: PMC2238985
Contributors: Wanchana S; Thongjuea S; Ulat VJ; Anacleto M; Mauleon R; Conte M; Rouard M; Ruiz M; Krishnamurthy N; Sjolander K et al.
Source: Self-asserted source
Supat Thongjuea via Europe PubMed Central

Peer review (4 reviews for 3 publications/grants)

Review activity for Communications biology. (1)
Review activity for Journal of human genetics. (1)
Review activity for Nature communications (2)
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