Personal information

Multiscale modeling , Heart, Cardiac electrophysiology, Biophysics and modelling of ion channels, Propagation of electrical signals in the heart, Modeling of diseased cardiac cells

Biography

I received the MSc degree in physical and biomedical electronics from the National University of Radio Electronics, Ukraine, and the PhD degree in biomedical engineering from Tel Aviv University, Israel (in 2017), specializing in multi-scale modeling of cardiac function. Alongside my PhD studies, I have led several successful industrial projects in the biopharmaceutical and medical device industry.

In my current postdoctoral position at the Faculty of Engineering, Bar-Ilan University, I specialize in developing new modeling approaches for biological networks (e.g., gene co-expression networks, gene regulatory networks, protein-protein interaction networks) through automated reasoning. My research aims to derive a highly predictive explanation for the control of cell differentiation in the C. elegans germline.

My main research interests are in the area of computational modeling with applications to biological and physiological systems. In terms of physiological systems, I want to focus my research on multi-scale computational modeling in a wide variety of clinical applications, including oncology, cardiac and neurodegenerative diseases, among others, with a strong emphasis on clinical translation of the developed techniques. In terms of biological systems, my research interests focus on the development of new models and tools for bio networks to explore cell signaling, cell population behavior, and the interplay between cells and their extracellular environment.

Activities

Employment (1)

Bar-Ilan University: Ramat Gan, ISRAEL, IL

2019-05-01 to present | Postdoctoral researcher (Faculty of Engineering)
Employment
Source: Self-asserted source
Ani Amar

Education and qualifications (1)

Tel Aviv University: Tel Aviv, Israel, IL

2017-02-12 to 2017-02-12 | PhD (Department of Biomedical Engineering)
Education
Source: Self-asserted source
Ani Amar

Works (8)

Virtual clinical QT exposure-response studies – A translational computational approach

Journal of Pharmacological and Toxicological Methods
2024-03 | Journal article
Part of ISSN: 1056-8719
Contributors: Jazmin Aguado-Sierra; Paula Dominguez-Gomez; Ani Amar; Constantine Butakoff; Michael Leitner; Stefan Schaper; Jan M. Kriegl; Borje Darpo; Mariano Vazquez; Georg Rast
Source: Self-asserted source
Ani Amar

Modeling the C. elegans germline stem cell genetic network using automated reasoning

Biosystems
2022-07 | Journal article
Contributors: Ani Amar; E. Jane Albert Hubbard; Hillel Kugler
Source: check_circle
Crossref

Three-dimensional (3D) Multiscale Model of the Contracting Ventricle

Proceedings of Virtual Physiological Human (VPH) conference
2018-09-07 | Conference paper
Source: Self-asserted source
Ani Amar

Simulation of Cellular Remodeling: from Cardiac Myofiber to Whole Heart

Journal of Neurology and Neuromedicine
2018-07 | Journal article
Source: Self-asserted source
Ani Amar

Mechano-electric feedback effects in a three-dimensional (3D) model of the contracting cardiac ventricle

PLOS ONE
2018-01-17 | Journal article
Contributors: Ani Amar; Elena Tolkacheva; Sharon Zlochiver; Ofer Barnea
Source: check_circle
Crossref
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Multiscale Interactions in a 3D Model of the Contracting Ventricle

Cardiovascular Engineering and Technology
2015-10-05 | Journal article
Part of ISSN: 1869-408X
Contributors: Ani Amar; Sharon Zlochiver; Ofer Barnea
Source: Self-asserted source
Ani Amar via Crossref Metadata Search
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Multiscale 3D model of cardiac contraction based on a fiber array

2012 IEEE 27th Convention of Electrical and Electronics Engineers in Israel
2012-11 | Conference paper
Part of ISBN: 9781467346818
Contributors: A. Amar; S. Witman; O. Barnea
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Ani Amar via Crossref Metadata Search
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A model of blood glucose level changes accounting for kidney function in humans.

5th International Forum of Young Scientists “Radio electronics and youth in the XXI century”.
2001-04-26 | Conference paper
Source: Self-asserted source
Ani Amar

Peer review (4 reviews for 2 publications/grants)

Review activity for Cardiovascular engineering and technology. (3)
Review activity for PloS one. (1)