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Employment (5)

Inter-University Center for Biomedical Research: Kottayam, Kerala, IN

2017-04-11 to present | Associate Professor (Center for Development and Aging Research)
Employment
Source: Self-asserted source
Goutam Chandra

Children's National Health System: Washington, DC, US

2015-06 to 2017-03 | Postdoctoral Research Fellow (Center for Genetic Medicine)
Employment
Source: Self-asserted source
Goutam Chandra

Rush University Medical Center: Chicago, IL, US

2014-02-17 to 2015-05-28 | Post-doctoral Fellow (Department of Neurological Sciences)
Employment
Source: Self-asserted source
Goutam Chandra

National Institutes of Health: Bethesda, MD, US

2008-12-29 to 2013-12-28 | Visiting Fellow (NICHD)
Employment
Source: Self-asserted source
Goutam Chandra

Himalayan Pharmacy Institute: East Sikkim, Sikkim, IN

2000-03 to 2002-03 | Assistant Professor (Department of Pharmaceutics)
Employment
Source: Self-asserted source
Goutam Chandra

Education and qualifications (2)

Indian Institute of Chemical Biology CSIR: Kolkata, WB, IN

2002-04-02 to 2008-12-24 | PhD (Neuropharmacology)
Education
Source: Self-asserted source
Goutam Chandra

Jadavpur University: Kolkata, West Bengal, IN

1998-09 to 2000-03 | M. Pharm. (Department of Pharmaceutical Technology)
Education
Source: Self-asserted source
Goutam Chandra

Works (31)

Secreted acid sphingomyelinase as a potential gene therapy for limb girdle muscular dystrophy 2B

Journal of Clinical Investigation
2022-01-04 | Journal article
Contributors: Daniel C. Bittel; Sen Chandra Sreetama; Goutam Chandra; Robin Ziegler; Kanneboyina Nagaraju; Jack H. Van der Meulen; Jyoti K. Jaiswal
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Anoctamin 5 Knockout Mouse Model Recapitulates LGMD2L Muscle Pathology and Offers Insight Into in vivo Functional Deficits

Journal of neuromuscular diseases
2021 | Journal article
EID:

2-s2.0-85122546595

Part of ISSN: 22143602
Contributors: Thiruvengadam, G.; Sreetama, S.C.; Charton, K.; Hogarth, M.; Novak, J.S.; Suel-Petat, L.; Chandra, G.; Allard, B.; Richard, I.; Jaiswal, J.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Coping with the calcium overload caused by cell injury: ER to the rescue

Cell Stress
2021 | Journal article
EID:

2-s2.0-85106384537

Part of ISSN: 25230204
Contributors: Chandra, G.; Mázala, D.A.G.; Jaiswal, J.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair

Journal of Cell Biology
2021 | Journal article
EID:

2-s2.0-85102905630

Part of ISSN: 15408140 00219525
Contributors: Chandra, G.; Sreetama, S.C.; Mázala, D.A.G.; Charton, K.; VanderMeulen, J.H.; Richard, I.; Jaiswal, J.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis

Journal of Inherited Metabolic Disease
2020 | Journal article
EID:

2-s2.0-85084129122

Part of ISSN: 15732665 01418955
Contributors: Sarkar, C.; Sadhukhan, T.; Bagh, M.B.; Appu, A.P.; Chandra, G.; Mondal, A.; Saha, A.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome

Annals of Neurology
2020 | Journal article
EID:

2-s2.0-85087316440

Part of ISSN: 15318249 03645134
Contributors: Foley, A.R.; Zou, Y.; Dunford, J.E.; Rooney, J.; Chandra, G.; Xiong, H.; Straub, V.; Voit, T.; Romero, N.; Donkervoort, S. et al.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

The light at the end of the tunnel gets vivid for spinal muscular atrophy: An Editorial Highlight for “Cerebrospinal fluid proteomic profiling in nusinersen-treated patients with spinal muscular atrophy” on page 650.

Journal of Neurochemistry
2020 | Journal article
EID:

2-s2.0-85081546153

Part of ISSN: 14714159 00223042
Contributors: Dutta, D.; Chandra, G.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair

Cells
2020-08 | Journal article | Author
Contributors: Daniel Bittel; Goutam Chandra; Laxmi M. S. Tirunagri; Arun B. Deora; Sushma Medikayala; Luana Scheffer; Aurelia Defour; Jyoti K. Jaiswal
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

Dysregulated calcium homeostasis prevents plasma membrane repair in Anoctamin 5/TMEM16E-deficient patient muscle cells

Cell Death Discovery
2019 | Journal article
EID:

2-s2.0-85071104137

Part of ISSN: 20587716
Contributors: Chandra, G.; Defour, A.; Mamchoui, K.; Pandey, K.; Mishra, S.; Mouly, V.; Sreetama, S.C.; Mahad Ahmad, M.; Mahjneh, I.; Morizono, H. et al.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Reinforcing mitochondrial functions in aging brain: An insight into Parkinson's disease therapeutics

Journal of Chemical Neuroanatomy
2019 | Journal article
EID:

2-s2.0-85041628920

Part of ISSN: 18736300 08910618
Contributors: Chandra, G.; Shenoi, R.A.; Anand, R.; Rajamma, U.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α

Journal of Neuroimmune Pharmacology
2018 | Journal article
EID:

2-s2.0-85035336405

Part of ISSN: 15571904 15571890
Contributors: Chandra, G.; Kundu, M.; Rangasamy, S.B.; Dasarathy, S.; Ghosh, S.; Watson, R.; Pahan, K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Membrane Stabilization by Modified Steroid Offers a Potential Therapy for Muscular Dystrophy Due to Dysferlin Deficit

Molecular Therapy
2018 | Journal article
EID:

2-s2.0-85053383372

Part of ISSN: 15250024 15250016
Contributors: Sreetama, S.C.; Chandra, G.; Van der Meulen, J.H.; Ahmad, M.M.; Suzuki, P.; Bhuvanendran, S.; Nagaraju, K.; Hoffman, E.P.; Jaiswal, J.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Induction of adaptive immunity leads to nigrostriatal disease progression in MPTP mouse model of Parkinson's disease

Journal of Immunology
2017 | Journal article
EID:

2-s2.0-85019953658

Part of ISSN: 15506606 00221767
Contributors: Chandra, G.; Roy, A.; Rangasamy, S.B.; Pahan, K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model

Nature Communications
2017 | Journal article
EID:

2-s2.0-85014743519

Part of ISSN: 20411723
Contributors: Bagh, M.B.; Peng, S.; Chandra, G.; Zhang, Z.; Singh, S.P.; Pattabiraman, N.; Liu, A.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Molecular recognition of genomic DNA in a condensate with a model surfactant for potential gene-delivery applications

Journal of Photochemistry and Photobiology B: Biology
2016 | Journal article
EID:

2-s2.0-84958243734

Part of ISSN: 18732682 10111344
Contributors: Singh, P.; Choudhury, S.; Chandra, G.K.; Lemmens, P.; Pal, S.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Neutralization of RANTES and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson disease

Journal of Biological Chemistry
2016 | Journal article
EID:

2-s2.0-84978405476

Part of ISSN: 1083351X 00219258
Contributors: Chandra, G.; Rangasamy, S.B.; Roy, A.; Kordower, J.H.; Pahan, K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders

Human Molecular Genetics
2015 | Journal article
EID:

2-s2.0-84943747165

Part of ISSN: 14602083 09646906
Contributors: Chandra, G.; Bagh, M.B.; Peng, S.; Saha, A.; Sarkar, C.; Moralle, M.; Zhang, Z.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Suppression of agrin-22 production and synaptic dysfunction in Cln1<sup>-/-</sup> mice

Annals of Clinical and Translational Neurology
2015 | Journal article
EID:

2-s2.0-85009104610

Part of ISSN: 23289503
Contributors: Peng, S.; Xu, J.; Pelkey, K.A.; Chandra, G.; Zhang, Z.; Bagh, M.B.; Yuan, X.; Wu, L.-G.; Mcbain, C.J.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Oral cysteamine bitartrate and N-acetylcysteine for patients with infantile neuronal ceroid lipofuscinosis: A pilot study

The Lancet Neurology
2014 | Journal article
EID:

2-s2.0-84904299248

Part of ISSN: 14744465 14744422
Contributors: Levin, S.W.; Baker, E.H.; Zein, W.M.; Zhang, Z.; Quezado, Z.M.N.; Miao, N.; Gropman, A.; Griffin, K.J.; Bianconi, S.; Chandra, G. et al.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-Ras product and growth-associated protein-43

Journal of Biological Chemistry
2013 | Journal article
EID:

2-s2.0-84875972777

Part of ISSN: 00219258 1083351X
Contributors: Kong, E.; Peng, S.; Chandra, G.; Sarkar, C.; Zhang, Z.; Bagh, M.B.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Neuroprotection and lifespan extension in Ppt1<sup>-/-</sup> mice by NtBuHA: Therapeutic implications for INCL

Nature Neuroscience
2013 | Journal article
EID:

2-s2.0-84886949159

Part of ISSN: 10976256 15461726
Contributors: Sarkar, C.; Chandra, G.; Peng, S.; Zhang, Z.; Liu, A.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: Amelioration by resveratrol

Human Molecular Genetics
2012 | Journal article
EID:

2-s2.0-84860437194

Part of ISSN: 09646906 14602083
Contributors: Saha, A.; Sarkar, C.; Singh, S.P.; Zhang, Z.; Munasinghe, J.; Peng, S.; Chandra, G.; Kong, E.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: Partial rescue by resveratrol

Human Molecular Genetics
2011 | Journal article
EID:

2-s2.0-79952019175

Part of ISSN: 09646906 14602083
Contributors: Wei, H.; Zhang, Z.; Saha, A.; Peng, S.; Chandra, G.; Quezado, Z.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs

Journal of Biological Chemistry
2010 | Journal article
EID:

2-s2.0-77951216203

Part of ISSN: 00219258 1083351X
Contributors: Saha, A.; Lee, Y.-C.; Zhang, Z.; Chandra, G.; Su, S.-B.; Mukherjee, A.B.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

A two-dimensional coordination compound as a zinc ion selective luminescent probe for biological applications

Chemistry - An Asian Journal
2007 | Journal article
EID:

2-s2.0-34548624721

Part of ISSN: 18614728 1861471X
Contributors: Dhara, K.; Karan, S.; Ratha, J.; Roy, P.; Chandra, G.; Manassero, M.; Mallik, B.; Banerjee, P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Unilateral implantation of dopamine-loaded biodegradable hydrogel in the striatum attenuates motor abnormalities in the 6-hydroxydopamine model of hemi-parkinsonism

Behavioural Brain Research
2007 | Journal article
EID:

2-s2.0-34548668709

Part of ISSN: 01664328
Contributors: Senthilkumar, K.S.; Saravanan, K.S.; Chandra, G.; Sindhu, K.M.; Jayakrishnan, A.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats

Brain Research
2006 | Journal article
EID:

2-s2.0-33644903828

Part of ISSN: 00068993
Contributors: Chandra, G.; Gangopadhyay, P.K.; Senthil Kumar, K.S.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Cystathionine beta-synthase T833C/844ins68 polymorphism and stroke [6]

Neurology India
2006 | Journal article
EID:

2-s2.0-33845341780

Part of ISSN: 00283886
Contributors: Chandra, G.; Pal, S.; Gangopadhyay, P.K.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Intrastriatal infusion of the Parkinsonian neurotoxin, MPP<sup>+</sup>, induces damage of striatal cell nuclei in Sprague-Dawley rats

Journal of Chemical Neuroanatomy
2006 | Journal article
EID:

2-s2.0-33751330408

Part of ISSN: 08910618
Contributors: Banerjee, R.; Sreetama, S.; Saravanan, K.S.; Chandra, G.; Nath De, S.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Swim-test as a function of motor impairment in MPTP model of Parkinson's disease: A comparative study in two mouse strains

Behavioural Brain Research
2005 | Journal article
EID:

2-s2.0-23744438056

Part of ISSN: 01664328
Contributors: Haobam, R.; Sindhu, K.M.; Chandra, G.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Calcium channel agonist, (±)-Bay K8644, causes a transient increase in striatal monoamine oxidase activity in Balb/c mice

Neuroscience Letters
2003 | Journal article
EID:

2-s2.0-0037448053

Part of ISSN: 03043940
Contributors: Samantaray, S.; Chandra, G.; Mohanakumar, K.P.
Source: Self-asserted source
Goutam Chandra via Scopus - Elsevier

Peer review (3 reviews for 3 publications/grants)

Review activity for Journal of neuroimmune pharmacology. (1)
Review activity for Neurochemistry international. (1)
Review activity for Translational psychiatry. (1)