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Employment (2)

Universidade de Coimbra: Coimbra, Coimbra, PT

2011-07-01 to 2015-08-31 | PhD Student (Medicine / Science and Technology)
Employment
Source: Self-asserted source
Sara R. Martins-Neves

Leiden University Medical Centre: Leiden, NL

2011-10-05 to 2013-12-20 | Visiting researcher (Department of Pathology)
Employment
Source: Self-asserted source
Sara R. Martins-Neves

Education and qualifications (2)

Universidade de Coimbra Faculdade de Ciencias e Tecnologia: Coimbra, Coimbra, PT

2011-04-01 to 2017-05-26 | Doctoral degree
Education
Source: Self-asserted source
Sara R. Martins-Neves

Faculty of Sciences and Technology of the University of Coimbra: Coimbra, PT

2005-09-22 to 2010-07-22 | Master
Education
Source: Self-asserted source
Sara R. Martins-Neves

Professional activities (1)

Faculty Opinions: London, GB

2013-10-08 to present | Associate Faculty Member
Invited position
Source: check_circle
Faculty Opinions

Funding (2)

Selective eradication of osteosarcoma stem cells by targeting Wnt/β-catenin signalling activity

2015-04 to 2016-03 | Grant
Liga Portuguesa contra o Cancro / CIMAGO (Lisbon / Coimbra, PT)
Source: Self-asserted source
Sara R. Martins-Neves

The role of Cancer Stem-like Cells in Osteosarcoma and their relevance in Therapy Response: in vitro and in vivo studies with PET

2011-04 to 2015-03 | Grant
Portuguese Foundation for Science and Tecnhology (Lisbon, PT)
GRANT_NUMBER:

SFRH/BD/69603/2010

Source: Self-asserted source
Sara R. Martins-Neves

Works (15)

Self-Renewal and Pluripotency in Osteosarcoma Stem Cells’ Chemoresistance: Notch, Hedgehog, and Wnt/β-Catenin Interplay with Embryonic Markers

International Journal of Molecular Sciences
2023-05-07 | Journal article
Contributors: Sara R. Martins-Neves; Gabriela Sampaio-Ribeiro; Célia M. F. Gomes
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Chemoresistance-Related Stem Cell Signaling in Osteosarcoma and Its Plausible Contribution to Poor Therapeutic Response: A Discussion That Still Matters

International Journal of Molecular Sciences
2022-09-27 | Journal article
Contributors: Sara R. Martins-Neves; Gabriela Sampaio-Ribeiro; Célia M. F. Gomes
Source: check_circle
Crossref

Therapy-induced enrichment of cancer stem-like cells in solid human tumors: Where do we stand?

Pharmacological research
2018-10 | Journal article
Contributors: Martins-Neves SR; Cleton-Jansen AM; Gomes CMF
Source: Self-asserted source
Sara R. Martins-Neves via Europe PubMed Central
grade
Preferred source (of 2)‎

Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells

Cancer Chemotherapy and Pharmacology
2018-01-30 | Journal article
Contributors: Daniela I. Paiva-Oliveira; Sara R. Martins-Neves; Antero J. Abrunhosa; Carlos Fontes-Ribeiro; Célia M. F. Gomes
Source: check_circle
Crossref

IWR-1, a tankyrase inhibitor, attenuates WNT/β-catenin signaling in cancer stem-like cells and inhibits in vivo the growth of a subcutaneous human osteosarcoma xenograft

Cancer Letters
2017-11 | Journal article
Part of ISSN: 0304-3835
Contributors: Sara R. Martins-Neves; Daniela I. Paiva-Oliveira; Carlos Fontes-Ribeiro; Judith V.M.G. Bovée; Anne-Marie Cleton-Jansen; Célia.M. F. Gomes
Source: Self-asserted source
Sara R. Martins-Neves via Crossref Metadata Search
grade
Preferred source (of 2)‎

Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.

2016-04 | Journal article
Contributors: Martins-Neves SR; Corver WE; Paiva-Oliveira DI; van den Akker BE; Briaire-de-Bruijn IH; Bovée JV; Gomes CM; Cleton-Jansen AM
Source: Self-asserted source
Sara R. Martins-Neves via Europe PubMed Central

Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling.

2016-01 | Journal article
Contributors: Martins-Neves SR; Paiva-Oliveira DI; Wijers-Koster PM; Abrunhosa AJ; Fontes-Ribeiro C; Bovée JV; Cleton-Jansen AM; Gomes CM
Source: Self-asserted source
Sara R. Martins-Neves via Europe PubMed Central

Sensitizing osteosarcoma stem cells to doxorubicin-induced apoptosis through retention of doxorubicin and modulation of apoptotic-related proteins

Life Sciences
2015-06-01 | Journal article
DOI:

10.1016/j.lfs.2015.03.009

Source: Self-asserted source
Sara R. Martins-Neves

Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line.

2012 | Journal article
Contributors: Martins-Neves SR; Lopes ÁO; do Carmo A; Paiva AA; Simões PC; Abrunhosa AJ; Gomes CM
Source: Self-asserted source
Sara R. Martins-Neves via Europe PubMed Central

Identifying Tumor-initiating Cells in Human Osteosarcoma Cell Lines – the Function Matters

European Journal of Cancer, Vol. 48 Supplement 5, Page S92
2012-07 | Conference poster
DOI:

10.1016/S0959-8049(12)71066-3

Source: Self-asserted source
Sara R. Martins-Neves

Identification of Cancer Stem Cells in Osteosarcoma and their implications in response to Chemotherapy

16th International Charles Heidelberger Symposium on Cancer Research
2010 | Conference abstract
SOURCE-WORK-ID:

cv-prod-id-2006215

Contributors: A. O. G. Lopes; S. R. M. Neves; A. do Carmo; A. A. Paiva; M. Botelho; C. M. F. Gomes
Source: check_circle
CIÊNCIAVITAE

Osteosarcoma contains a subpopulation of Cancer Stem-like Cells that are highly resistant to Radiotherapy

16th Charles Heidelberger Symposium on Cancer Research
2010 | Conference abstract
SOURCE-WORK-ID:

cv-prod-id-2006216

Contributors: Neves, Sara Raquel Martins; A. O. G. Lopes; A. do Carmo; A. J. Abrunhosa; P. C. P. S. Simões; A. A. Paiva; M. Botelho; C. M. F. Gomes
Source: check_circle
CIÊNCIAVITAE

Assessing metabolic activity of cancer stem cells during differentiation with [18F]FDG

Eur J Nucl Med Mol Imaging (2010) 37 (Suppl 2)
2010-10 | Conference paper
DOI:

10.1007/s00259-010-1559-1

Source: Self-asserted source
Sara R. Martins-Neves
grade
Preferred source (of 2)‎

Cancer stem cell populations in osteosarcoma: implications for [18F]FDG uptake and response to therapy

Proceedings of the Annual Congress of the European Association of Nuclear Medicine, Vienna 2010
2010-10 | Conference abstract
DOI:

10.1007/s00259-010-1557-3

Source: Self-asserted source
Sara R. Martins-Neves
grade
Preferred source (of 2)‎

Role of Cancer Stem Cells in [18F]FDG Uptake and Therapy Response in Osteosarcoma

Mol Imaging Biol (2010) 12 (Suppl 2):S605
2010-09-10 | Conference abstract
Source: Self-asserted source
Sara R. Martins-Neves

Peer review (10 reviews for 6 publications/grants)

Review activity for Cancers. (2)
Review activity for Cellular and molecular life sciences (2)
Review activity for Current issues in molecular biology. (1)
Review activity for International journal of molecular sciences. (3)
Review activity for Journal of translational medicine. (1)
Review activity for Onco. (1)