Personal information

Emails & domains

Verified email domains

Websites & social links

Integrative human genomics site
Dept PHPC site

Keywords

Functional genetics, Psychiatric disease, Cardiovascular disease, Post-GWAS, Genetic epidemiology

Countries

United Kingdom, Australia

Activities

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Employment (4)

University of South Australia: Adelaide, South Australia, AU

2023-03-01 to present | Research Fellow (Clinical and Health Sciences)
Employment
Source: Self-asserted source
David Stacey

University of Cambridge Department of Public Health and Primary Care: Cambridge, Cambridgeshire, GB

2016-02-07 to 2023-01-26 | Postdoctoral Research Associate (Cardiovascular Epidemiology Unit)
Employment
Source: Self-asserted source
David Stacey

University of Adelaide: SA, SA, AU

2013-01-29 to 2015-12-15 | Lecturer (0.6 FTE) | Research Officer (0.4 FTE) (Discipline of Psychiatry)
Employment
Source: Self-asserted source
David Stacey

King's College London Institute of Psychiatry Psychology and Neuroscience: London, London, GB

2011-10-01 to 2012-09-30 | Postdoctoral Research Associate (Social, Genetic, and Developmental Psychiatry)
Employment
Source: Self-asserted source
David Stacey

Education and qualifications (4)

University of Adelaide: SA, SA, AU

2013-02-01 to 2014-12-01 | Graduate Certificate in Higher Education
Qualification
Source: Self-asserted source
David Stacey

King's College London Institute of Psychiatry Psychology and Neuroscience: London, London, GB

2008-10-01 to 2011-09-30 | PhD (Social, Genetic, and Developmental Psychiatry)
Qualification
Source: Self-asserted source
David Stacey

King's College London Institute of Psychiatry Psychology and Neuroscience: London, London, GB

2007-10-01 to 2008-09-30 | MSc Neuroscience
Qualification
Source: Self-asserted source
David Stacey

University of Greenwich: London, GB

2004-10-01 to 2007-09-30 | BSc (hons) Psychology
Qualification
Source: Self-asserted source
David Stacey

Funding (2)

Lithium treatment response in bipolar disorder: functional characterisation of a genome-wide association study and a systems biology analysis using next generation RNA sequence data

2015-01 to 2015-12 | Grant
Royal Adelaide Hospital Research Fund (SA, SA, AU)
Source: Self-asserted source
David Stacey

Identification of transcriptomic alterations in major depressive disorder cases exhibiting peripheral inflammation using next generation RNA sequencing technology

2014-01 to 2014-12 | Grant
Royal Adelaide Hospital Research Fund (SA, SA, AU)
Source: Self-asserted source
David Stacey

Works (47)

The contribution of genetic determinants of blood gene expression and splicing to molecular phenotypes and health outcomes

Nature Genetics
2025-03 | Journal article
DOI: 10.1038/s41588-025-02096-3
Contributors: Alex Tokolyi; Elodie Persyn; Artika P. Nath; Katie L. Burnham; Jonathan Marten; Thomas Vanderstichele; Manuel Tardaguila; David Stacey; Ben Farr; Vivek Iyer et al.
Source: check_circle
Crossref

In-silico functional analyses identifyTMPRSS15-mediated intestinal absorption of lithium as a modulator of lithium response in bipolar disorder

2024-03-28 | Preprint
DOI: 10.1101/2024.03.27.24304993
Contributors: David Stacey; Vijayaprakash Suppiah; Beben Benyamin; S Hong Lee; Elina Hyppönen
Source: check_circle
Crossref

A metabolome-wide Mendelian randomization study identifies dysregulated arachidonic acid synthesis as a potential causal risk factor for bipolar disorder

Biological Psychiatry
2024-02 | Journal article
DOI: 10.1016/j.biopsych.2024.02.1005
Contributors: David Stacey; Beben Benyamin; S Hong Lee; Elina Hyppönen
Source: check_circle
Crossref

A metabolome-wide Mendelian randomization study identifies dysregulated arachidonic acid synthesis as a potential causal risk factor for bipolar disorder

2024-02-20 | Preprint
DOI: 10.1101/2024.02.18.24302998
Contributors: David Stacey; Beben Benyamin; S Hong Lee; Elina Hyppönen
Source: check_circle
Crossref

A transcriptome-wide Mendelian randomization study in isolated human immune cells highlights risk genes involved in viral infections and potential drug repurposing opportunities for schizophrenia

2024-02-20 | Preprint
DOI: 10.1101/2024.02.18.24303002
Contributors: David Stacey; Liam Gaziano; Preethi Eldi; Catherine Toben; Beben Benyamin; S Hong Lee; Elina Hyppönen
Source: check_circle
Crossref

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.

Nature immunology
2023-08-10 | Journal article
DOI: 10.1038/s41590-023-01588-w
PMID: 37563310
PMC: PMC10457199
Contributors: Zhao JH; Stacey D; Niclas Eriksson; Erin Macdonald-Dunlop; Hedman Ã…K; Kalnapenkis A; Stefan Enroth; Domenico Cozzetto; Digby-Bell J; Marten J et al.
Source: Self-asserted source
David Stacey

Multi-omics data integration methods and their applications in psychiatric disorders.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
2023-01-25 | Journal article
DOI: 10.1016/j.euroneuro.2023.01.001
PMID: 36706689
Contributors: Sathyanarayanan A; Mueller TT; Ali Moni M; Schueler K; ECNP TWG Network members; Baune BT; Lio P; Mehta D; Baune BT; Dierssen M et al.
Source: Self-asserted source
David Stacey

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.

Nature communications
2022-03-09 | Journal article
DOI: 10.1038/s41467-022-28729-3
PMID: 35264566
Source: Self-asserted source
David Stacey

Transcriptional biomarkers of response to pharmacological treatments in severe mental disorders: A systematic review.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
2022-01-08 | Journal article
DOI: 10.1016/j.euroneuro.2021.12.005
PMID: 35016057
Source: Self-asserted source
David Stacey

Recommendations for pharmacotranscriptomic profiling of drug response in CNS disorders.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
2021-11-04 | Journal article
DOI: 10.1016/j.euroneuro.2021.10.005
PMID: 34743061
Source: Self-asserted source
David Stacey

Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.

BMC medicine
2021-09-10 | Journal article
DOI: 10.1186/s12916-021-02087-1
PMID: 34503513
PMC: PMC8431908
Source: Self-asserted source
David Stacey

Genome-wide association study of circulating interleukin 6 levels identifies novel loci.

Human molecular genetics
2021-04-01 | Journal article
DOI: 10.1093/hmg/ddab023
PMID: 33517400
PMC: PMC8098112
Source: Self-asserted source
David Stacey

Downregulated transferrin receptor in the blood predicts recurrent MDD in the elderly cohort: A fuzzy forests approach.

Journal of affective disorders
2020-02-05 | Journal article
DOI: 10.1016/j.jad.2020.02.001
PMID: 32063571
Source: Self-asserted source
David Stacey

An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.

Journal of proteome research
2019-04-26 | Journal article
DOI: 10.1021/acs.jproteome.8b00786
PMID: 30887811
PMC: PMC6558644
Source: Self-asserted source
David Stacey

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.

Nucleic acids research
2019-01-01 | Journal article
DOI: 10.1093/nar/gky837
PMID: 30239796
PMC: PMC6326795
Source: Self-asserted source
David Stacey

Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults.

Journal of psychiatric research
2018-10-01 | Journal article
DOI: 10.1016/j.jpsychires.2018.09.017
PMID: 30312913
Source: Self-asserted source
David Stacey

A gene co-expression module implicating the mitochondrial electron transport chain is associated with long-term response to lithium treatment in bipolar affective disorder.

Translational psychiatry
2018-09-05 | Journal article
DOI: 10.1038/s41398-018-0237-0
PMID: 30185780
PMC: PMC6125294
Source: Self-asserted source
David Stacey

From lipid locus to drug target through human genomics.

Cardiovascular research
2018-07-01 | Journal article
DOI: 10.1093/cvr/cvy120
PMID: 29800275
Source: Self-asserted source
David Stacey

Genomic atlas of the human plasma proteome.

Nature
2018-06-06 | Journal article
DOI: 10.1038/s41586-018-0175-2
PMID: 29875488
PMC: PMC6697541
Source: Self-asserted source
David Stacey

Targeted proteomic analysis of cognitive dysfunction in remitted major depressive disorder: Opportunities of multi-omics approaches towards predictive, preventive, and personalized psychiatry.

Journal of proteomics
2018-02-21 | Journal article
DOI: 10.1016/j.jprot.2018.02.023
PMID: 29474866
Source: Self-asserted source
David Stacey

Interaction between childhood maltreatment on immunogenetic risk in depression: Discovery and replication in clinical case-control samples.

Brain, behavior, and immunity
2017-09-01 | Journal article
DOI: 10.1016/j.bbi.2017.08.023
PMID: 28867280
Source: Self-asserted source
David Stacey

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression.

Molecular psychiatry
2017-04-04 | Journal article
DOI: 10.1038/mp.2017.44
PMID: 28373689
PMC: PMC5628077
Source: Self-asserted source
David Stacey

TNF receptors 1 and 2 exert distinct region-specific effects on striatal and hippocampal grey matter volumes (VBM) in healthy adults.

Genes, brain, and behavior
2016-10-04 | Journal article
DOI: 10.1111/gbb.12318
PMID: 27528091
Source: Self-asserted source
David Stacey

Cytokine levels in major depression are related to childhood trauma but not to recent stressors.

Psychoneuroendocrinology
2016-07-15 | Journal article
DOI: 10.1016/j.psyneuen.2016.07.205
PMID: 27448525
Source: Self-asserted source
David Stacey

A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.

Journal of psychiatry & neuroscience : JPN
2016-04-01 | Journal article
DOI: 10.1503/jpn.150138
PMID: 26679926
PMC: PMC4853210
Source: Self-asserted source
David Stacey

A systematic review on the association between inflammatory genes and cognitive decline in non-demented elderly individuals.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
2015-12-11 | Journal article
DOI: 10.1016/j.euroneuro.2015.12.017
PMID: 26718789
Source: Self-asserted source
David Stacey

Peripheral blood gene expression analysis implicates B lymphocyte proliferation and ribosomal S26 transcripts in cognitive dysfunction in people with remitted Major Depression.

Journal of affective disorders
2015-11-17 | Journal article
DOI: 10.1016/j.jad.2015.11.022
PMID: 26610074
Source: Self-asserted source
David Stacey

Evidence of an IFN-γ by early life stress interaction in the regulation of amygdala reactivity to emotional stimuli.

Psychoneuroendocrinology
2015-08-13 | Journal article
DOI: 10.1016/j.psyneuen.2015.08.008
PMID: 26313134
Source: Self-asserted source
David Stacey

The Brain's Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample.

The American journal of psychiatry
2015-06-18 | Journal article
DOI: 10.1176/appi.ajp.2015.14101298
PMID: 26085042
Source: Self-asserted source
David Stacey

Global genetic variations predict brain response to faces.

PLoS genetics
2014-08-14 | Journal article
DOI: 10.1371/journal.pgen.1004523
PMID: 25122193
PMC: PMC4133042
Source: Self-asserted source
David Stacey

Neuropsychosocial profiles of current and future adolescent alcohol misusers.

Nature
2014-07-02 | Journal article
DOI: 10.1038/nature13402
PMID: 25043041
PMC: PMC4486207
Source: Self-asserted source
David Stacey

No evidence of DISC1-associated morphological changes in the hippocampus, anterior cingulate cortex, or striatum in major depressive disorder cases and healthy controls.

Journal of affective disorders
2014-05-11 | Journal article
DOI: 10.1016/j.jad.2014.05.001
PMID: 25012417
Source: Self-asserted source
David Stacey

Multimodal imaging of a tescalcin (TESC)-regulating polymorphism (rs7294919)-specific effects on hippocampal gray matter structure.

Molecular psychiatry
2014-04-29 | Journal article
DOI: 10.1038/mp.2014.39
PMID: 24776739
Source: Self-asserted source
David Stacey

DRD2/ANKK1 polymorphism modulates the effect of ventral striatal activation on working memory performance.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
2014-04-09 | Journal article
DOI: 10.1038/npp.2014.83
PMID: 24713612
PMC: PMC4138745
Source: Self-asserted source
David Stacey

A phenotypic structure and neural correlates of compulsive behaviors in adolescents.

PloS one
2013-11-14 | Journal article
DOI: 10.1371/journal.pone.0080151
PMID: 24244633
PMC: PMC3828212
Source: Self-asserted source
David Stacey

Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events.

Biological psychiatry
2013-10-08 | Journal article
DOI: 10.1016/j.biopsych.2013.07.043
PMID: 24120094
Source: Self-asserted source
David Stacey

Evidence of increased risk for major depressive disorder in individuals homozygous for the high-expressing 5-HTTLPR/rs25531 (L(A)) allele of the serotonin transporter promoter.

Psychiatric genetics
2013-10-01 | Journal article
DOI: 10.1097/ypg.0000000000000006
PMID: 23969989
Source: Self-asserted source
David Stacey

Neural mechanisms of attention-deficit/hyperactivity disorder symptoms are stratified by MAOA genotype.

Biological psychiatry
2013-06-05 | Journal article
DOI: 10.1016/j.biopsych.2013.03.027
PMID: 23746540
Source: Self-asserted source
David Stacey

White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms.

Molecular psychiatry
2013-04-30 | Journal article
DOI: 10.1038/mp.2013.44
PMID: 23628983
PMC: PMC3965837
Source: Self-asserted source
David Stacey

RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.

Proceedings of the National Academy of Sciences of the United States of America
2012-12-05 | Journal article
DOI: 10.1073/pnas.1211844110
PMID: 23223532
PMC: PMC3529066
Source: Self-asserted source
David Stacey

Hormonal contraceptives, menstrual cycle and brain response to faces.

Social cognitive and affective neuroscience
2012-11-21 | Journal article
DOI: 10.1093/scan/nss128
PMID: 23175677
PMC: PMC3907931
Source: Self-asserted source
David Stacey

Identification of common variants associated with human hippocampal and intracranial volumes.

Nature genetics
2012-04-15 | Journal article
DOI: 10.1038/ng.2250
PMID: 22504417
PMC: PMC3635491
Source: Self-asserted source
David Stacey

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.

Proceedings of the National Academy of Sciences of the United States of America
2011-04-06 | Journal article
DOI: 10.1073/pnas.1017288108
PMID: 21471458
PMC: PMC3084048
Source: Self-asserted source
David Stacey

Creating probabilistic maps of the face network in the adolescent brain: a multicentre functional MRI study.

Human brain mapping
2011-03-17 | Journal article
DOI: 10.1002/hbm.21261
PMID: 21416563
PMC: PMC6869899
Source: Self-asserted source
David Stacey

Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents.

NeuroImage
2011-02-22 | Journal article
DOI: 10.1016/j.neuroimage.2011.02.019
PMID: 21316467
Source: Self-asserted source
David Stacey

The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology.

Molecular psychiatry
2010-12-01 | Journal article
DOI: 10.1038/mp.2010.4
PMID: 21102431
Source: Self-asserted source
David Stacey

The genetics of alcoholism.

Current psychiatry reports
2009-10-01 | Journal article
DOI: 10.1007/s11920-009-0055-4
PMID: 19785977
Source: Self-asserted source
David Stacey

Peer review (9 reviews for 7 publications/grants)

Review activity for American journal of human genetics. (1)
Review activity for Communications biology. (1)
Review activity for Metabolism, clinical and experimental. (1)
Review activity for Osteoarthritis and cartilage open. (2)
Review activity for Progress in neuro-psychopharmacology & biological psychiatry. (2)
Review activity for Psychiatry research. (1)
Review activity for Translational psychiatry. (1)
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