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Employment (1)

University of Washington: Seattle, Washington, US

(Obstetrics and Gynecology)
Employment
Source: Self-asserted source
Sean M Hughes

Works (29)

Memory T cells possess an innate-like function in local protection from mucosal infection

Journal of Clinical Investigation
2023-05-15 | Journal article
DOI: 10.1172/JCI162800
Contributors: Tanvi Arkatkar; Veronica Davé; Irene Cruz Talavera; Jessica B. Graham; Jessica L. Swarts; Sean M. Hughes; Timothy A. Bell; Pablo Hock; Joe Farrington; Ginger D. Shaw et al.
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Stable HIV Reservoir Despite Prolonged Low-Dose Mycophenolate to Limit CD4+ T-cell Proliferation

Open Forum Infectious Diseases
2022-12-02 | Journal article
DOI: 10.1093/ofid/ofac620
Part of ISSN: 2328-8957
Contributors: Joshua T Schiffer; Claire Levy; Sean M Hughes; Urvashi Pandey; Mel Padullo; Keith Jerome; Haiying Zhu; Katrina Puckett; Eric Helgeson; Robert D Harrington et al.
Source: Self-asserted source
Sean M Hughes

Starting to have sexual intercourse is associated with increases in cervicovaginal immune mediators in young women: a prospective study and meta-analysis

eLife
2022-10-25 | Journal article
DOI: 10.7554/eLife.78565
Contributors: Sean M Hughes; Claire N Levy; Fernanda L Calienes; Katie A Martinez; Stacy Selke; Kenneth Tapia; Bhavna H Chohan; Lynda Oluoch; Catherine Kiptinness; Anna Wald et al.
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Cervicovaginal immune mediators increase when young women begin to have sexual intercourse: a prospective study and meta-analysis

2022-04-01 | Preprint
DOI: 10.1101/2022.03.31.22273275
Contributors: Sean M. Hughes; Claire N. Levy; Fernanda L. Calienes; Katie A. Martinez; Stacy Selke; Kenneth Tapia; Bhavna H. Chohan; Lynda Oluoch; Catherine Kiptinness; Anna Wald et al.
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Crossref

Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators

American Journal of Reproductive Immunology
2021-08 | Journal article
DOI: 10.1111/aji.13412
Contributors: Sean M. Hughes; Urvashi Pandey; Christine Johnston; Jeanne Marrazzo; Florian Hladik; Elizabeth Micks
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A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir

Cell Reports Medicine
2021-04 | Journal article
DOI: 10.1016/j.xcrm.2021.100243
Contributors: Claire N. Levy; Sean M. Hughes; Pavitra Roychoudhury; Daniel B. Reeves; Chelsea Amstuz; Haiying Zhu; Meei-Li Huang; Yulun Wei; Marta E. Bull; Noah A.J. Cassidy et al.
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Flt3-L enhances trans-epithelial migration and antigen presentation of dendritic cells adoptively transferred to genital mucosa

Journal of Controlled Release
2020-10 | Journal article
DOI: 10.1016/j.jconrel.2020.10.012
PMID: 33035616
Source: Self-asserted source
Sean M Hughes

Treatment with Commonly Used Antiretroviral Drugs Induces a Type I/III Interferon Signature in the Gut in the Absence of HIV Infection

Cell Reports Medicine
2020-09 | Journal article
DOI: 10.1016/j.xcrm.2020.100096
DOI: 10.1101/701961
PMID: 33015651
Source: Self-asserted source
Sean M Hughes
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Mechanisms of endogenous HIV-1 reactivation by endocervical epithelial cells.

Journal of virology
2020-02-12 | Journal article
DOI: 10.1128/jvi.01904-19
PMID: 32051273
Source: Self-asserted source
Sean M Hughes
grade
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Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses

PLOS ONE
2019-10-17 | Journal article
DOI: 10.1371/journal.pone.0223901
Contributors: Lucia Vojtech; Geetha P. Bansal; Mengying Zhang; Veronica Davé; Claire Levy; Sean M. Hughes; Ruofan Wang; Fernanda Calienes; Martin Prlic; Elizabeth Nance et al.
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Crossref

A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract.

Mucosal immunology
2019-07-16 | Journal article
DOI: 10.1038/s41385-019-0186-9
PMID: 31312028
Source: Self-asserted source
Sean M Hughes

Hybrid nanocarriers incorporating mechanistically distinct drugs for lymphatic CD4 + T cell activation and HIV-1 latency reversal

Science Advances
2019-03 | Journal article
DOI: 10.1126/sciadv.aav6322
Contributors: Shijie Cao; Sarah D. Slack; Claire N. Levy; Sean M. Hughes; Yonghou Jiang; Christopher Yogodzinski; Pavitra Roychoudhury; Keith R. Jerome; Joshua T. Schiffer; Florian Hladik et al.
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Cryopreservation of human mucosal tissues

PLOS ONE
2018-07-30 | Journal article
DOI: 10.1371/journal.pone.0200653
DOI: https://doi.org/10.1101/262519
Source: Self-asserted source
Sean M Hughes
grade
Preferred source (of 3)‎

Optimization and comparison of CD4-targeting lipid-polymer hybrid nanoparticles using different binding ligands

Journal of Biomedical Materials Research Part A
2018-01-10 | Journal article
DOI: 10.1002/jbm.a.36315
Part of ISSN: 1549-3296
Contributors: Shijie Cao; Yonghou Jiang; Claire N. Levy; Sean M. Hughes; Hangyu Zhang; Florian Hladik; Kim A. Woodrow
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Anti-proliferative therapy for HIV cure: a compound interest approach

Scientific Reports
2017-06-21 | Journal article
DOI: 10.1038/s41598-017-04160-3
Contributors: Daniel B. Reeves; Elizabeth R. Duke; Sean M. Hughes; Martin Prlic; Florian Hladik; Joshua T. Schiffer
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Crossref

plater: Read, Tidy, and Display Data from Microtiter Plates

The Journal of Open Source Software
2016-11-08 | Journal article
DOI: 10.21105/joss.00106
Contributors: Sean M Hughes
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Crossref

Cryopreservation of Human Mucosal Leukocytes

PLOS ONE
2016-05-27 | Journal article
DOI: 10.1371/journal.pone.0156293
DOI: 10.1101/039578
Source: Self-asserted source
Sean M Hughes
grade
Preferred source (of 3)‎

A study of the osmotic characteristics, water permeability, and cryoprotectant permeability of human vaginal immune cells

Cryobiology
2016-03 | Journal article
DOI: 10.1016/j.cryobiol.2016.03.003
Contributors: Zhiquan Shu; Sean M. Hughes; Cifeng Fang; Jinghua Huang; Baiwen Fu; Gang Zhao; Michael Fialkow; Gretchen Lentz; Florian Hladik; Dayong Gao
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Determination of the Membrane Permeability to Water of Human Vaginal Mucosal Immune Cells at Subzero Temperatures Using Differential Scanning Calorimetry

Biopreservation and Biobanking
2016-03 | Journal article
DOI: 10.1089/bio.2015.0079
Contributors: Zhiquan Shu; Sean M. Hughes; Cifeng Fang; Zhiyuan Hou; Gang Zhao; Michael Fialkow; Gretchen Lentz; Florian Hladik; Dayong Gao
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Sean M Hughes via Crossref Metadata Search

Vaccination Produces CD4 T Cells with a Novel CD154-CD40-Dependent Cytolytic Mechanism

The Journal of Immunology
2015-08 | Journal article
DOI: 10.4049/jimmunol.1501118
Contributors: R. N. Coler; T. Hudson; S. Hughes; P.-w. D. Huang; E. A. Beebe; M. T. Orr
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Effect of Mucosal Cytokine Administration on Selective Expansion of Vaginal Dendritic Cells to Support Nanoparticle Transport

Am J Reprod Immunol
2015-06 | Journal article
DOI: 10.1111/aji.12409
Contributors: Renuka Ramanathan; Jaehyung Park; Sean M. Hughes; William R. Lykins; Hunter R. Bennett; Florian Hladik; Kim A. Woodrow
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Mucosal effects of tenofovir 1% gel

eLife
2015-02-03 | Journal article
DOI: 10.7554/elife.04525
Contributors: Florian Hladik; Adam Burgener; Lamar Ballweber; Raphael Gottardo; Lucia Vojtech; Slim Fourati; James Y Dai; Mark J Cameron; Johanna Strobl; Sean M Hughes et al.
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Quantitative and stoichiometric analysis of the microRNA content of exosomes

Proceedings of the National Academy of Sciences
2014-09 | Journal article
DOI: 10.1073/pnas.1408301111
Contributors: J. R. Chevillet; Q. Kang; I. K. Ruf; H. A. Briggs; L. N. Vojtech; S. M. Hughes; H. H. Cheng; J. D. Arroyo; E. K. Meredith; E. N. Gallichotte et al.
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Sean M Hughes via Crossref Metadata Search

HIV-1 Specific IgA Detected in Vaginal Secretions of HIV Uninfected Women Participating in a Microbicide Trial in Southern Africa Are Primarily Directed Toward gp120 and gp140 Specificities

PLoS ONE
2014-07 | Journal article
DOI: 10.1371/journal.pone.0101863
Contributors: Kelly E. Seaton; Lamar Ballweber; Audrey Lan; Michele Donathan; Sean Hughes; Lucia Vojtech; M. Anthony Moody; Hua-Xin Liao; Barton F. Haynes; Christine G. Galloway et al.
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

Nucleic Acids Research
2014-05 | Journal article
DOI: 10.1093/nar/gku347
Contributors: L. Vojtech; S. Woo; S. Hughes; C. Levy; L. Ballweber; R. P. Sauteraud; J. Strobl; K. Westerberg; R. Gottardo; M. Tewari et al.
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Sean M Hughes via Crossref Metadata Search

Optimizing Viable Leukocyte Sampling from the Female Genital Tract for Clinical Trials: An International Multi-Site Study

PLoS ONE
2014-01 | Journal article
DOI: 10.1371/journal.pone.0085675
Contributors: Lyle R. McKinnon; Sean M. Hughes; Stephen C. De Rosa; Jeffrey A. Martinson; Jill Plants; Kirsten E. Brady; Pamela P. Gumbi; Devin J. Adams; Lucia Vojtech; Christine G. Galloway et al.
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Sean M Hughes via Crossref Metadata Search

Comprehensive Assessment of HIV Target Cells in the Distal Human Gut Suggests Increasing HIV Susceptibility Toward the Anus

JAIDS Journal of Acquired Immune Deficiency Syndromes
2013 | Journal article
DOI: 10.1097/qai.0b013e3182898392
Contributors: M. J. McElrath; K. Smythe; J. Randolph-Habecker; K. R. Melton; T. A. Goodpaster; S. M. Hughes; M. Mack; A. Sato; G. Diaz; G. Steinbach et al.
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Sean M Hughes via Crossref Metadata Search

Properties and mechanisms of spontaneous activity in the embryonic chick hindbrain

Devel Neurobio
2009-07 | Journal article
DOI: 10.1002/dneu.20712
Contributors: Sean M. Hughes; Curtis R. Easton; Martha M. Bosma
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search

Love and Work: The Legacy of Early University Entrance

Gifted Child Quarterly
2007-04-01 | Journal article
DOI: 10.1177/0016986207299472
Contributors: K. D. Noble; R. C. Vaughan; C. Chan; S. Childers; B. Chow; A. Federow; S. Hughes
Source: Self-asserted source
Sean M Hughes via Crossref Metadata Search
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