Personal information

Websites & social links

Linkedin public profile

Other IDs

Scopus Author ID: 6506533791
ResearcherID: F-7676-2016
Scopus Author ID: 57969672800

Keywords

Drug Discovery, Natural Products Chemistry, Structural elucidation

Countries

Spain

Activities

Collapse all

Employment (3)

Fundacion MEDINA: Granada, Andalucia, ES

2015-10-01 to present | Senior Scientist (Natural Products Chemistry)
Employment
Source: Self-asserted source
Francisco Javier Ortiz-López

nLife Therapeutics: Granada, Andalucia, ES

2012-10-01 to 2015-08-31 | Senior Research Fellow (Bioconjugation chemistry)
Employment
Source: Self-asserted source
Francisco Javier Ortiz-López

Fundacion MEDINA: Granada, Andalucia, ES

2010-03-08 to 2012-06-30 | Postdoctoral Research Fellow (Natural Products Chemistry)
Employment
Source: Self-asserted source
Francisco Javier Ortiz-López

Works (38)

Genome-Led Discovery of the Antibacterial Cyclic Lipopeptide Kutzneridine A and Its Silent Biosynthetic Gene Cluster from Kutzneria Species

Journal of Natural Products
2024-10-25 | Journal article
DOI: 10.1021/acs.jnatprod.4c00633
Contributors: Francisco Javier Ortiz-López; Daniel Oves-Costales; Jaime Felipe Guerrero Garzón; Tetiana Gren; Eva Baggesgaard Sterndorff; Xinglin Jiang; Tue Sparholt Jo̷rgensen; Kai Blin; Ignacio Fernández-Pastor; José R. Tormo et al.
Source: check_circle
Crossref

Genome Mining for Diazo-Synthesis-Related Genes in Streptomyces sp. CS057 Unveiled the Cryptic Biosynthetic Gene Cluster crx for the Novel 3,4-AHBA-Derived Compound Crexazone 2

Biomolecules
2024-08-29 | Journal article
DOI: 10.3390/biom14091084
Contributors: Laura Prado-Alonso; Suhui Ye; Ignacio Pérez-Victoria; Ignacio Montero; Pedro Riesco; Francisco Javier Ortiz-López; Jesús Martín; Carlos Olano; Fernando Reyes; Carmen Méndez
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Dilarmycins A–C, Calcium-Dependent Lipopeptide Antibiotics with a Non-canonical Ca2+-Binding Motif

Organic Letters
2024-02-23 | Journal article
DOI: 10.1021/acs.orglett.3c04195
Contributors: Ignacio Fernández-Pastor; Francisco Javier Ortiz-López; Daniel Oves-Costales; Jesús Martín; Pilar Sánchez; Ángeles Melguizo; Fernando Reyes; Tilmann Weber; Olga Genilloud
Source: check_circle
Crossref

Identification and heterologous expression of the globomycin biosynthetic gene cluster

Synthetic and Systems Biotechnology
2023 | Journal article
DOI: 10.1016/j.synbio.2023.02.001
EID:

2-s2.0-85147720163

Part of ISSN: 2405805X
Contributors: Oves-Costales, D.; Gren, T.; Sterndorff, E.B.; Martín, J.; Ortiz-López, F.J.; Jørgensen, T.S.; Jiang, X.; Román-Hurtado, F.; Reyes, F.; Genilloud, O. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Crossiellidines A–F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp.

Organic Letters
2023-05-19 | Journal article
DOI: 10.1021/acs.orglett.3c01088
Contributors: Francisco Javier Ortiz-López; Daniel Oves-Costales; Daniel Carretero-Molina; Jesús Martín; Caridad Díaz; Mercedes de la Cruz; Fernando Román-Hurtado; María Álvarez-Arévalo; Tue Sparholt Jørgensen; Fernando Reyes et al.
Source: check_circle
Crossref

Dual targeting of the class V lanthipeptide antibiotic cacaoidin

iScience
2023-04 | Journal article
DOI: 10.1016/j.isci.2023.106394
Part of ISSN: 2589-0042
Contributors: Julia P. Deisinger; Melina Arts; Ioli Kotsogianni; Jan-Samuel Puls; Fabian Grein; Francisco Javier Ortiz-López; Nathaniel I. Martin; Anna Müller; Olga Genilloud; Tanja Schneider
Source: Self-asserted source
Francisco Javier Ortiz-López

Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family

Organic Chemistry Frontiers
2022 | Journal article
DOI: 10.1039/D1QO01480C
Contributors: Daniel Carretero-Molina; Francisco Javier Ortiz-López; Tetiana Gren; Daniel Oves-Costales; Jesús Martín; Fernando Román-Hurtado; Tue Sparholt Jørgensen; Mercedes de la Cruz; Caridad Díaz; Francisca Vicente et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Natural products, including a new caboxamycin, from Streptomyces and other Actinobacteria isolated in Spain from storm clouds transported by Northern winds of Arctic origin

Frontiers in Chemistry
2022-11-03 | Journal article
DOI: 10.3389/fchem.2022.948795
Part of ISSN: 2296-2646
Contributors: Aida Sarmiento-Vizcaíno; Jesús Martín; Francisco Javier Ortiz-López; Fernando Reyes; Luis A. García; Gloria Blanco
Source: Self-asserted source
Francisco Javier Ortiz-López
grade
Preferred source (of 2)‎

Complete genome sequence of Amycolatopsis sp. CA-230715, encoding a 35-module type I polyketide synthase

Microbiology Resource Announcements
2021 | Journal article
DOI: 10.1128/MRA.00805-21
EID:

2-s2.0-85115758452

Part of ISSN: 2576098X
Contributors: Jørgensen, T.S.; Gren, T.; Oves-Costales, D.; Ortiz-López, F.J.; Carretero-Molina, D.; González, I.; Blin, K.; Genilloud, O.; Weber, T.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Identification of the 216kbp gene cluster and structure elucidation of gargantulides B and C, new complex 52-membered macrolides from Amycolatopsis sp.

bioRxiv
2021 | Other
DOI: 10.1101/2021.08.11.455926
EID:

2-s2.0-85115731145

Part of ISSN: 26928205
Contributors: Carretero-Molina, D.; Ortiz-López, F.J.; Gren, T.; Oves-Costales, D.; Martín, J.; Román-Hurtado, F.; Jørgensen, T.S.; de la Cruz, M.; Díaz, C.; Vicente, F. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods

Molecules
2021-10-30 | Journal article
DOI: 10.3390/molecules26216580
Contributors: Charlotte Beck; Tetiana Gren; Francisco Javier Ortiz-López; Tue Sparholt Jørgensen; Daniel Carretero-Molina; Jesús Martín Serrano; José R. Tormo; Daniel Oves-Costales; Eftychia E. Kontou; Omkar S. Mohite et al.
Source: check_circle
Crossref
grade
Preferred source (of 4)‎

Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260

ACS Chemical Biology
2021-08-20 | Journal article
DOI: 10.1021/acschembio.1c00318
Contributors: Eftychia Eva Kontou; Tetiana Gren; Francisco Javier Ortiz-López; Emil Thomsen; Daniel Oves-Costales; Caridad Díaz; Mercedes de la Cruz; Xinglin Jiang; Tue Sparholt Jørgensen; Kai Blin et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Pentaminomycins F and G, Nonribosomal Peptides Containing 2-Pyridylalanine

Journal of Natural Products
2021-04-23 | Journal article
DOI: 10.1021/acs.jnatprod.0c01199
Part of ISSN: 0163-3864
Part of ISSN: 1520-6025
Source: Self-asserted source
Francisco Javier Ortiz-López
grade
Preferred source (of 2)‎

Biosynthesis and Heterologous Expression of Cacaoidin, the First Member of the Lanthidin Family of RiPPs

Antibiotics
2021-04-08 | Journal article
DOI: 10.3390/antibiotics10040403
Contributors: Fernando Román-Hurtado; Marina Sánchez-Hidalgo; Jesús Martín; Francisco Ortiz-López; Olga Genilloud
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from <i>Streptomyces cacaoi</i> CA-170360

Microorganisms
2021-01 | Journal article | Author
DOI: 10.3390/microorganisms9010135
Contributors: Fernando Román-Hurtado; Marina Sánchez-Hidalgo; Jesús Martín; Francisco Javier Ortiz-López; Daniel Carretero-Molina; Fernando Reyes; Olga Genilloud
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

Pentaminomycins F and G, First Non-Ribosomal Peptides Containing 2-Pyridylalanine

[]
2020-11-09 | Preprint
DOI: 10.26434/chemrxiv.13142786.v1
Source: Self-asserted source
Francisco Javier Ortiz-López
grade
Preferred source (of 2)‎

One pathway, two cyclic pentapeptides: heterologous expression of BE-18257 A-C and pentaminomycins A-E from Streptomyces cacaoi CA-170360

2020-10-24 | Other
DOI: 10.1101/2020.10.23.352575
Contributors: Fernando Román-Hurtado; Marina Sánchez-Hidalgo; Jesús Martín; Francisco Javier Ortiz-López; Daniel Carretero-Molina; Fernando Reyes; Olga Genilloud
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Cacaoidin, First Member of the New Lanthidin RiPP Family

Angewandte Chemie
2020-07-27 | Journal article
DOI: 10.1002/ange.202005187
Contributors: Francisco Javier Ortiz‐López; Daniel Carretero‐Molina; Marina Sánchez‐Hidalgo; Jesús Martín; Ignacio González; Fernando Román‐Hurtado; Mercedes de la Cruz; Sergio García‐Fernández; Fernando Reyes; Julia Patricia Deisinger et al.
Source: check_circle
Crossref

Cacaoidin, First Member of the New Lanthidin RiPP Family

Angewandte Chemie International Edition
2020-07-27 | Journal article
DOI: 10.1002/anie.202005187
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Francisco Javier Ortiz-López
grade
Preferred source (of 3)‎

Frontispiece: Cacaoidin, First Member of the New Lanthidin RiPP Family

Angewandte Chemie International Edition
2020-07-27 | Journal article
DOI: 10.1002/anie.202083161
Contributors: Francisco Javier Ortiz‐López; Daniel Carretero‐Molina; Marina Sánchez‐Hidalgo; Jesús Martín; Ignacio González; Fernando Román‐Hurtado; Mercedes de la Cruz; Sergio García‐Fernández; Fernando Reyes; Julia Patricia Deisinger et al.
Source: check_circle
Crossref

Frontispiz: Cacaoidin, First Member of the New Lanthidin RiPP Family

Angewandte Chemie
2020-07-27 | Journal article
DOI: 10.1002/ange.202083161
Contributors: Francisco Javier Ortiz‐López; Daniel Carretero‐Molina; Marina Sánchez‐Hidalgo; Jesús Martín; Ignacio González; Fernando Román‐Hurtado; Mercedes de la Cruz; Sergio García‐Fernández; Fernando Reyes; Julia Patricia Deisinger et al.
Source: check_circle
Crossref

Structural Elucidation of Antibiotic TKR2999, an Antifungal Lipodepsipeptide Isolated from the Fungus <i>Foliophoma fallens</i>

Antibiotics
2020-05 | Journal article | Author
DOI: 10.3390/antibiotics9060278
Contributors: Gloria Crespo; Ignacio Pérez-Victoria; Francisco Javier Ortiz-López; Victor Gonzalez-Menendez; MERCEDES DE LA CRUZ MORENO; Bastien Cautain; Pilar Sánchez; Francisca Vicente Perez; Olga Genilloud; Fernando Reyes
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

Biosynthesis and heterologous expression of cacaoidin, the first member of the lanthidin family of RiPPs

2020-05-22 | Preprint
DOI: 10.1101/2020.05.20.105809
Contributors: Fernando Román-Hurtado; Marina Sánchez-Hidalgo; Jesús Martín; Francisco Javier Ortíz-López; Olga Genilloud
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

New Napyradiomycin Analogues from <i>Streptomyces</i> sp. Strain CA-271078

Marine Drugs
2019-12 | Journal article | Author
DOI: 10.3390/md18010022
Contributors: Daniel Carretero-Molina; Francisco Javier Ortiz-López; Jesús Martín; Daniel Oves-Costales; Caridad Díaz; MERCEDES DE LA CRUZ MORENO; Bastien Cautain; Francisca Vicente Perez; Olga Genilloud; Fernando Reyes
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

New 3-Hydroxyquinaldic Acid Derivatives from Cultures of the Marine Derived Actinomycete <i>Streptomyces cyaneofuscatus</i> M-157

Marine Drugs
2018-10 | Journal article | Author
DOI: 10.3390/md16100371
Contributors: Francisco Javier Ortiz-López; Elsa Alcalde; Aida Sarmiento-Vizcaíno; Caridad Díaz; Bastien Cautain; Luis A. García; Gloria Blanco; Fernando Reyes
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 3)‎

Protective effects of isolecanoric acid on neurodegenerative in vitro models

Neuropharmacology
2016 | Journal article
DOI: 10.1016/j.neuropharm.2015.09.029
EID:

2-s2.0-84948467243
Contributors: De Pedro, N.; Cantizani, J.; Ortiz-López, F.J.; González-Menéndez, V.; Cautain, B.; Rodríguez, L.; Bills, G.F.; Reyes, F.; Genilloud, O.; Vicente, F.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier
grade
Preferred source (of 2)‎

Cyclic colisporifungin and linear cavinafungins, antifungal lipopeptides isolated from Colispora cavincola

Journal of Natural Products
2015 | Journal article
DOI: 10.1021/np500854j
EID:

2-s2.0-84925934767
Contributors: Ortíz-López, F.J.; Monteiro, M.C.; González-Menéndez, V.; Tormo, J.R.; Genilloud, O.; Bills, G.F.; Vicente, F.; Zhang, C.; Roemer, T.; Singh, S.B. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y)

Neuroscience Letters
2015 | Journal article
DOI: 10.1016/j.neulet.2015.03.010
EID:

2-s2.0-84925278388
Contributors: Muñoz-Sáez, E.; de Munck García, E.; Arahuetes Portero, R.M.; Vicente, F.; Ortiz-López, F.J.; Cantizani, J.; Miguel, B.G.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Compounds potentiating the activity of antifungal drugs

2014 | Patent
Source: Self-asserted source
Francisco Javier Ortiz-López

Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis

BMC Genomics
2013 | Journal article
DOI: 10.1186/1471-2164-14-339
EID:

2-s2.0-84877859261
Contributors: Chen, L.; Yue, Q.; Zhang, X.; Xiang, M.; Wang, C.; Li, S.; Che, Y.; Ortiz-López, F.J.; Bills, G.F.; Liu, X. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Uso de compuestos orto-dépsidos como agentes neuroprotectores

2013 | Patent
Source: Self-asserted source
Francisco Javier Ortiz-López

Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica

Journal of Natural Products
2012 | Journal article
DOI: 10.1021/np3000987
EID:

2-s2.0-84866468978
Contributors: Pérez-Victoria, I.; Martín, J.; González-Menéndez, V.; De Pedro, N.; El Aouad, N.; Ortiz-López, F.J.; Tormo, J.R.; Platas, G.; Vicente, F.; Bills, G.F. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Lasionectrin, a naphthopyrone from a Lasionectria sp.

Journal of Natural Products
2012 | Journal article
DOI: 10.1021/np3002942
EID:

2-s2.0-84866458503
Contributors: El Aouad, N.; Pérez-Moreno, G.; Sánchez, P.; Cantizani, J.; Ortiz-López, F.J.; Martín, J.; González-Menéndez, V.; Ruiz-Pérez, L.M.; González-Pacanowska, D.; Vicente, F. et al.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Chiral high-performance liquid chromatographic separation and circular dichroism spectra of the enantiomers of cytotoxic aristocularine alkaloids

Journal of Chromatography A
2006 | Journal article
DOI: 10.1016/j.chroma.2006.07.077
EID:

2-s2.0-33748312015
Contributors: Caccamese, S.; Scivoli, G.; Bianca, S.; López-Romero, J.M.; Ortiz-López, F.J.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Erratum: Fragmentation of carbohydrate anomeric alkoxyl radicals. Synthesis of highly functionalized chiral vinyl sulfones (Tetrahedron Letters (2005) 46 (5265) DOI: 10.1016/j.tetlet.2005.06.043)

Tetrahedron Letters
2006 | Journal article
DOI: 10.1016/j.tetlet.2005.12.035
EID:

2-s2.0-30944462942
Contributors: Alonso-Cruz, C.R.; León, E.I.; Ortiz-López, F.J.; Rodríguez, M.S.; Suárez, E.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Fragmentation of carbohydrate anomeric alkoxyl radicals. Synthesis of highly functionalized chiral vinyl sulfones

Tetrahedron Letters
2005 | Journal article
DOI: 10.1016/j.tetlet.2005.06.043
EID:

2-s2.0-21844462579
Contributors: Alonso-Cruz, C.R.; León, E.I.; Ortiz-López, F.J.; Rodríguez, M.S.; Suárez, E.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier
grade
Preferred source (of 2)‎

The palladium(0) Suzuki cross-coupling reaction as the key step in the synthesis of aporphinoids

Tetrahedron
2004 | Journal article
DOI: 10.1016/j.tet.2004.05.014
EID:

2-s2.0-2942521185
Contributors: Suau, R.; Rico, R.; Nájera, F.; Ortiz-López, F.J.; López-Romero, J.M.; Moreno-Mañas, M.; Roglans, A.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Synthesis of 3,4-dioxocularine and aristocularine alkaloids in aconvergentroute from aryloxy-phenyl acetamides involving oxalyl chloride-lewisacid

Arkivoc
2002 | Journal article
EID:

2-s2.0-3242764613
Contributors: Suau, R.; Rico, R.; López-Romero, J.M.; Nájera, F.; Ruiz, A.; Ortiz-López, F.J.
Source: Self-asserted source
Francisco Javier Ortiz-López via Scopus - Elsevier

Peer review (4 reviews for 2 publications/grants)

Review activity for Angewandte Chemie. (2)
Review activity for Nature communications (2)
How many people are using ORCID?