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Employment (2)

University of Washington: Seattle, WA, US

2017-07-01 to present | Research Associate Professor (Pathology)
Employment
Source: Self-asserted source
Alan Herr

University of Washington: Seattle, WA, US

2008-12-01 to 2017-06-30 | Research Assistant Professor (Pathology)
Employment
Source: Self-asserted source
Alan Herr

Education and qualifications (3)

University of Washington: Seattle, WA, US

2005-10-01 to 2008-11-30 | Senior Fellow (Pathology)
Qualification
Source: Self-asserted source
Alan Herr

Sainsbury Laboratory: Norwich, Norfolk, GB

2000-04-10 to 2005-04-30 | Post-doctoral Fellow (Sainsbury Laboratory)
Qualification
Source: Self-asserted source
Alan Herr

University of Utah: Salt Lake City, UT, US

1993-09-01 to 2000-03-30 | Ph.D (Human Genetics)
Education
Source: Self-asserted source
Alan Herr

Funding (1)

Volatility of mutator phenotypes at single cell resolution

2016-06-13 to 2021-05-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: R01GM118854
Source: Self-asserted source
Alan Herr via DimensionsWizard

Works (31)

A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae

eLife
2021-09-15 | Journal article
Contributors: Pengyao Jiang; Anja R Ollodart; Vidha Sudhesh; Alan J Herr; Maitreya J Dunham; Kelley Harris
Source: check_circle
Crossref

A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation withinSaccharomyces cerevisiae

2021-01-11 | Preprint
Contributors: Pengyao Jiang; Anja R. Ollodart; Vidha Sudhesh; Alan J. Herr; Maitreya J. Dunham; Kelley Harris
Source: check_circle
Crossref

Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles

Communications Biology
2021-01-04 | Journal article
Contributors: Ian T. Dowsett; Jessica L. Sneeden; Branden J. Olson; Jill McKay-Fleisch; Emma McAuley; Scott R. Kennedy; Alan J. Herr
Source: check_circle
Crossref

Rate volatility and asymmetric segregation diversify mutation burden in mutator cells

2020-06-22 | Preprint
Contributors: I.T. Dowsett; J. Sneeden; B.J. Olson; J. McKay-Fleisch; E. McAuley; S.R. Kennedy; A.J. Herr
Source: check_circle
Crossref

Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes

Proceedings of the National Academy of Sciences
2019-02-19 | Journal article
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Alan Herr

Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variant.

Scientific reports
2017-04-18 | Journal article
Source: Self-asserted source
Alan Herr

POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome.

Human mutation
2015-08-06 | Journal article
Source: Self-asserted source
Alan Herr

Volatility of Mutator Phenotypes at Single Cell Resolution.

PLoS genetics
2015-04-13 | Journal article
Source: Self-asserted source
Alan Herr

dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.

Proceedings of the National Academy of Sciences of the United States of America
2015-03-31 | Journal article
Source: Self-asserted source
Alan Herr

DNA replication error-induced extinction of diploid yeast.

Genetics
2014-01-03 | Journal article
Source: Self-asserted source
Alan Herr

Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.

Genetics
2013-01-10 | Journal article
Source: Self-asserted source
Alan Herr

Somatic mutations in aging, cancer and neurodegeneration.

Mechanisms of ageing and development
2011-11-03 | Journal article
Source: Self-asserted source
Alan Herr

Antimutator variants of DNA polymerases.

Critical reviews in biochemistry and molecular biology
2011-10-06 | Journal article
Source: Self-asserted source
Alan Herr

Mutator suppression and escape from replication error-induced extinction in yeast.

PLoS genetics
2011-10-06 | Journal article
Source: Self-asserted source
Alan Herr

DNA replication fidelity and cancer.

Seminars in cancer biology
2010-10-15 | Journal article
Source: Self-asserted source
Alan Herr

An SNF2 protein associated with nuclear RNA silencing and the spread of a silencing signal between cells in Arabidopsis.

The Plant cell
2007-05-25 | Journal article
Source: Self-asserted source
Alan Herr
grade
Preferred source (of 2)‎

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.

Proceedings of the National Academy of Sciences of the United States of America
2006-09-28 | Journal article
Source: Self-asserted source
Alan Herr

Pathways through the small RNA world of plants.

FEBS letters
2005-09-02 | Journal article
Source: Self-asserted source
Alan Herr

RNA polymerase IV directs silencing of endogenous DNA.

Science (New York, N.Y.)
2005-02-03 | Journal article
Source: Self-asserted source
Alan Herr

Silence is green.

Biochemical Society transactions
2004-12-01 | Journal article
Source: Self-asserted source
Alan Herr

Modulation of floral development by a gibberellin-regulated microRNA.

Development (Cambridge, England)
2004-07-01 | Journal article
Source: Self-asserted source
Alan Herr

Factors that influence selection of coding resumption sites in translational bypassing: minimal conventional peptidyl-tRNA:mRNA pairing can suffice.

The Journal of biological chemistry
2004-01-05 | Journal article
Source: Self-asserted source
Alan Herr

RNA silencing pathways in plants.

Cold Spring Harbor symposia on quantitative biology
2004-01-01 | Journal article
Source: Self-asserted source
Alan Herr

Drop-off during ribosome hopping.

Journal of molecular biology
2001-08-01 | Journal article
Source: Self-asserted source
Alan Herr

Analysis of the roles of tRNA structure, ribosomal protein L9, and the bacteriophage T4 gene 60 bypassing signals during ribosome slippage on mRNA.

Journal of molecular biology
2001-06-01 | Journal article
Source: Self-asserted source
Alan Herr

Overriding standard decoding: implications of recoding for ribosome function and enrichment of gene expression.

Cold Spring Harbor symposia on quantitative biology
2001-01-01 | Journal article
Source: Self-asserted source
Alan Herr

One protein from two open reading frames: mechanism of a 50 nt translational bypass.

The EMBO journal
2000-06-01 | Journal article
Source: Self-asserted source
Alan Herr

The 23 S rRNA environment of ribosomal protein L9 in the 50 S ribosomal subunit.

Journal of molecular biology
2000-04-01 | Journal article
Source: Self-asserted source
Alan Herr

Coupling of open reading frames by translational bypassing.

Annual review of biochemistry
2000-01-01 | Journal article
Source: Self-asserted source
Alan Herr

Mutations which alter the elbow region of tRNA2Gly reduce T4 gene 60 translational bypassing efficiency.

The EMBO journal
1999-05-01 | Journal article
Source: Self-asserted source
Alan Herr

Efficiency of T4 gene 60 translational bypassing.

Journal of bacteriology
1998-04-01 | Journal article
PMID: 9537381
Source: Self-asserted source
Alan Herr

Peer review (1 review for 1 publication/grant)

Review activity for PLOS genetics. (1)