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Employment (1)

Mansoura University Faculty of Pharmacy: Mansoura, Eldakahlia, EG

2019-11-01 to present | Lecturer (Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Mahmoud Elshal

Education and qualifications (1)

Mansoura University Faculty of Pharmacy: Mansoura, Eldakahlia, EG

2019-11-01 to present | phD (Pharmacology and Toxicology)
Education
Source: Self-asserted source
Mahmoud Elshal

Works (15)

Bioactivity of Eriocephalus africanus essential oil against concanavalin A-induced hepatitis via suppressing immune cell infiltration, inhibiting TNF-a/NF-?B and IFN-?/STAT1 signaling pathways

Journal of Ethnopharmacology
2024 | Journal article
Contributors: Haikal, Abdullah; Galala, Amal A.; Elshal, Mahmoud; Amen, Yhiya; Gohar, Ahmed A.
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Inhibitory effect of diacerein on diclofenac-induced acute nephrotoxicity in rats<i> via</i> modulating SIRT1/HIF-1α/NF-κB and SIRT1/p53 regulatory axes

International Immunopharmacology
2024 | Journal article
Contributors: Mansoure, Abduallah Nasser; Elshal, Mahmoud; Helal, Manar G.
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Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways

Toxicology and Applied Pharmacology
2024 | Journal article
Contributors: Abdulaal, Wesam H.; Omar, Ulfat M.; Zeyadi, Mustafa; El-Agamy, Dina S.; Alhakamy, Nabil A.; Ibrahim, Sabrin R. M.; Almalki, Naif A. R.; Asfour, Hani Z.; Al-Rabia, Mohammed W.; Mohamed, Gamal A. et al.
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Renoprotective effect of diacetylrhein on diclofenac-induced acute kidney injury in rats via modulating Nrf2/NF-κB/NLRP3/GSDMD signaling pathways

Food and Chemical Toxicology
2024 | Journal article
Contributors: Mansoure, Abduallah Nasser; Elshal, Mahmoud; Helal, Manar G.
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Targeting Nrf2/HO-1 and NF-κB/TNF-α signaling pathways with empagliflozin protects against atrial fibrillation-induced acute kidney injury in rats

Toxicology
2024 | Journal article
Contributors: Badreldin, Hussein; El-Karef, Amr; Ibrahim, Tarek; Elshal, Mahmoud
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Targeting SIRT1/AMPK/Nrf2/NF-κB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury

Toxicology
2024 | Journal article
Contributors: Mosaoa, Rami M.; Al-Rabia, Mohammed W.; Asfour, Hani Z.; Alhakamy, Nabil A.; Mansouri, Rasha A.; El-Agamy, Dina S.; Abdulaal, Wesam H.; Mohamed, Gamal A.; Ibrahim, Sabrin R. M.; Elshal, Mahmoud
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Modulation of the crosstalk between Keap1/Nrf2/HO-1 and NF-κB signaling pathways by Tomatidine protects against inflammation/oxidative stress-driven fulminant hepatic failure in mice

International Immunopharmacology
2024-03 | Journal article | Author
Part of ISSN: 1567-5769
Contributors: Wesam H. Abdulaal; Ulfat M. Omar; Mustafa Zeyadi; Dina S. El-Agamy; Nabil A. Alhakamy; Sabrin R.M. Ibrahim; Naif A.R. Almalki; Hani Z. Asfour; Mohammed W. Al-Rabia; Gamal A. Mohamed et al.
Source: Self-asserted source
Mahmoud Elshal
grade
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Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents

Journal of Enzyme Inhibition and Medicinal Chemistry
2023-12-31 | Journal article
Part of ISSN: 1475-6366
Part of ISSN: 1475-6374
Contributors: Mohammad M. Al-Sanea; Abdelrahman Hamdi; Simone Brogi; Samar S. Tawfik; Dina I. A. Othman; Mahmoud Elshal; Hidayat Ur Rahman; Della G. T. Parambi; Rehab M. Elbargisy; Samy Selim et al.
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Mahmoud Elshal
grade
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Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-alpha/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice

Inflammopharmacology
2022 | Journal article
Contributors: Elshal, Mahmoud; Hazem, Sara H.
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Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases

Cells
2022 | Journal article
Contributors: Eltanani, Shaimaa; Yumnamcha, Thangal; Gregory, Andrew; Elshal, Mahmoud; Shawky, Mohamed; Ibrahim, Ahmed S.
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Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier

Environmental Toxicology and Pharmacology
2022-04 | Journal article
Part of ISSN: 1382-6689
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Mahmoud Elshal
grade
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Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways

Archives of Pharmacal Research
2022-03-04 | Journal article
Part of ISSN: 0253-6269
Part of ISSN: 1976-3786
Source: Self-asserted source
Mahmoud Elshal
grade
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Etanercept attenuates immune-mediated hepatitis induced by concanavalin A <i>via</i> differential regulation of the key effector cytokines of CD4+T cells

Life Sciences
2021 | Journal article
Contributors: Elshal, Mahmoud; Abu-Elsaad, Nashwa; El-Karef, Amr; Ibrahim, Tarek
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Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+T cells infiltration

International Immunopharmacology
2019 | Journal article
Contributors: Elshal, Mahmoud; Abu-Elsaad, Nashwa; El-Karef, Amr; Ibrahim, Tarek
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The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis

Naunyn-Schmiedeberg's Archives of Pharmacology
2015 | Journal article
Contributors: Elshal, Mahmoud; Abu-Elsaad, Nashwa; El-Karef, Amr; Ibrahim, Tarek Mostafa
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Peer review (13 reviews for 7 publications/grants)

Review activity for Archives of pharmacal research. (2)
Review activity for Archives of pharmacal research. (2)
Review activity for BMC complementary medicine and therapies. (1)
Review activity for Frontiers in pharmacology. (1)
Review activity for Journal of applied pharmaceutical science. (1)
Review activity for Journal of ethnopharmacology. (5)
Review activity for Phytotherapy research. (1)