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Gold–Protein Composite Nanoparticles for Enhanced X-ray Interactions: A Potential Formulation for Triggered Release

Pharmaceutics
2021-09-04 | Journal article
Contributors: Courtney van Ballegooie; Alice Man; Alessia Pallaoro; Marcel Bally; Byron D. Gates; Donald T. Yapp
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Using a Microfluidics System to Reproducibly Synthesize Protein Nanoparticles: Factors Contributing to Size, Homogeneity, and Stability

Processes
2019-05-15 | Journal article
Contributors: Courtney van Ballegooie; Alice Man; Irene Andreu; Byron D. Gates; Donald Yapp
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High content analysis (HCA) of nanoparticle uptake by mammalian cells and their effects on motility, proliferation and viability

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
2018 | Conference paper
Source: Self-asserted source
Donald Yapp

In Vivo Validation of PAPSS1 (3′-phosphoadenosine 5′-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target

Clinical Cancer Research
2017 | Journal article
Source: Self-asserted source
Donald Yapp

Inactivation of the kinase domain of CDK10 prevents tumor growth in a preclinical model of colorectal cancer, and is accompanied by downregulation of Bcl-2

Molecular cancer therapeutics
2017 | Journal article
Source: Self-asserted source
Donald Yapp

P1. 03-020 Detection of Hypoxia Using EF5 PET/CT in 10 Patients with Advanced NSCLC Receiving Chemotherapy with and without Bevacizumab

Journal of Thoracic Oncology
2017 | Journal article
Source: Self-asserted source
Donald Yapp

P1.03-020 Detection of Hypoxia Using EF5 PET/CT in 10 Patients with Advanced NSCLC Receiving Chemotherapy with and without Bevacizumab

Journal of Thoracic Oncology
2017-11 | Journal article
Part of ISSN: 1556-0864
Contributors: F. Lacroix-Poisson; F. Benard; D. Wilson; M. Adam; D. Yapp; C. Ho; J. Laskin
Source: Self-asserted source
Donald Yapp via Crossref Metadata Search

In VivoValidation of PAPSS1 (3′-phosphoadenosine 5′-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target

Clinical Cancer Research
2017-08-08 | Journal article
Part of ISSN: 1078-0432
Contributors: Ada W.Y. Leung; Chansey J. Veinotte; Nicole Melong; Min Hee Oh; Kent Chen; Katey S.S. Enfield; Ian Backstrom; Corinna Warburton; Donald Yapp; Jason N. Berman et al.
Source: Self-asserted source
Donald Yapp via Crossref Metadata Search

Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2

Molecular Cancer Therapeutics
2017-06 | Journal article
Part of ISSN: 1535-7163
Contributors: Louis-Bastien Weiswald; Mohammad R. Hasan; John C.T. Wong; Clarissa C. Pasiliao; Mahbuba Rahman; Jianhua Ren; Yaling Yin; Samuel Gusscott; Sophie Vacher; Andrew P. Weng et al.
Source: Self-asserted source
Donald Yapp via Crossref Metadata Search

Overexpression of HER-2 in MDA-MB-435/LCC6 tumours is associated with higher metabolic activity and lower energy stress

Scientific reports
2016 | Journal article
Source: Self-asserted source
Donald Yapp

The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth

Angiogenesis
2016 | Journal article
Source: Self-asserted source
Donald Yapp

[18F] 5-fluoro aminosuberic acid (FASu) for oxidative stress imaging in breast cancer

Journal of Nuclear Medicine
2015 | Journal article
Source: Self-asserted source
Donald Yapp

A new 18F-RBF3 radioprosthetic for one step aqueous labeling of peptides and other ligands: meeting the challenge of radiosynthetic ease and preclinical impact ie high specific activity and high T: NT ratios

Journal of Nuclear Medicine
2015 | Journal article
Source: Self-asserted source
Donald Yapp

Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma

Journal of Controlled Release
2015 | Journal article
Source: Self-asserted source
Donald Yapp

Induction of cytotoxicity in pyridine analogues of the anti-metastatic Ru (III) complex NAMI-A by ferrocene functionalization

Inorganic chemistry
2015 | Journal article
Source: Self-asserted source
Donald Yapp

Investigating autophagy and glutamine metabolism as therapeutic targets for pancreatic cancer.

2015 | Other
Source: Self-asserted source
Donald Yapp

Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer

Journal of Controlled Release
2015 | Journal article
Source: Self-asserted source
Donald Yapp

Nitroimidazole-Containing H2dedpa and H2 CHX dedpa Derivatives as Potential PET Imaging Agents of Hypoxia with 68Ga

Inorganic chemistry
2015 | Journal article
Source: Self-asserted source
Donald Yapp

The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion

BMC cancer
2015 | Journal article
Source: Self-asserted source
Donald Yapp

A new 18 F-heteroaryltrifluoroborate radio-prosthetic with greatly enhanced stability that is labelled by 18 F--19 F-isotope exchange in good yield at high specific activity

MedChemComm
2014 | Journal article
Source: Self-asserted source
Donald Yapp

A simple route to [11C] N-Me labeling of aminosuberic acid for proof of feasibility imaging of the xC- transporter

Bioorganic & medicinal chemistry letters
2014 | Journal article
Source: Self-asserted source
Donald Yapp

An Organotrifluoroborate for broadly applicable one-step 18F-labeling

Angewandte Chemie International Edition
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and-resistant triple-negative breast cancer

Clinical Cancer Research
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Dual mode fluorescent 18F-PET tracers: Efficient modular synthesis of rhodamine-[cRGD] 2-[18F]-organotrifluoroborate, rapid, and high yielding one-step 18F-Labeling at high specific activity, and correlated in vivo PET imaging and ex vivo fluorescence

Bioconjugate chemistry
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Dual mode fluorescent PET tracers: Efficient modular synthesis, facile 18F-radiolabelling, in vivo PET imaging and ex vivo fluorescence

Journal of Nuclear Medicine
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid

Journal of Nuclear Medicine
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Innentitelbild: An Organotrifluoroborate for Broadly Applicable One-Step 18F-Labeling (Angew. Chem. 44/2014)

Angewandte Chemie
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Inside Cover: An Organotrifluoroborate for Broadly Applicable One-Step 18F-Labeling (Angew. Chem. Int. Ed. 44/2014)

Angewandte Chemie International Edition
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Oxidative stress imaging in triple negative breast cancer using a cystine transporter tracer [18F] 5-fluoro aminosuberic acid (FASu)

Journal of Nuclear Medicine
2014 | Journal article
Source: Self-asserted source
Donald Yapp

The Phosphoinositide-Dependent Kinase-1 Inhibitor 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] phenyl]-acetamide (OSU-03012) Prevents Y-Box Binding Protein-1 from Inducing Epidermal Growth Factor Receptor (vol 72, pg 641, 2007)

MOLECULAR PHARMACOLOGY
2014 | Journal article
Source: Self-asserted source
Donald Yapp

Autophagy inhibition as an effective strategy for sensitizing triple-negative breast cancer cells to chemotherapy.

2013 | Other
Source: Self-asserted source
Donald Yapp

Capturing aqueous 18F-fluoride with boron: One-step 18F-labeling of dimeric cycloRGD at high specific activity for functional PET imaging of tumors in mice

Journal of Nuclear Medicine
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Development of 18F-labelled aminosuberic acid derivatives for in vivo analysis of cystine transporter expression and oxidative stress

Journal of Nuclear Medicine
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Imaging tumor vasculature noninvasively with positron emission tomography and RGD peptides labeled with copper 64 using the bifunctonal chelates DOTA, oxo-DO3a. and PCTA

Molecular imaging
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Increasing the bioavailability of RuIII anticancer complexes through hydrophobic albumin interactions

Chemistry--A European Journal
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Kit-like 18F-labeling of RGD-19F-arytrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivo tumor imaging

Nuclear medicine and biology
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Novel 18F-radiolabeling of RGD at Super High Specific Activity by Isotope Exchange

BIOPOLYMERS
2013 | Conference paper
Source: Self-asserted source
Donald Yapp

One step F-18-Labeling of Complex Peptides for Functional PET Imaging

BIOPOLYMERS
2013 | Conference paper
Source: Self-asserted source
Donald Yapp

Single step 18F-labeling of dimeric cycloRGD for functional PET imaging of tumors in mice

Nuclear medicine and biology
2013 | Journal article
Source: Self-asserted source
Donald Yapp

Synthesis, characterization, and biological studies of emissive rhenium--glutamine conjugates

JBIC Journal of Biological Inorganic Chemistry
2013 | Journal article
Source: Self-asserted source
Donald Yapp

18F COMPOUNDS FOR CANCER IMAGING AND METHODS FOR THEIR USE

2013-03 | Other
Source: Self-asserted source
Donald Yapp

68Ga small peptide imaging: comparison of NOTA and PCTA

Bioconjugate chemistry
2012 | Journal article
Source: Self-asserted source
Donald Yapp

A CB-TE2A bifunctional chelate applicable to immunoPET with 64Cu

Journal of Nuclear Medicine
2012 | Journal article
Source: Self-asserted source
Donald Yapp

Irinophore C, a liposomal formulation of irinotecan, has anti-vascular effects in primary tumors of colorectal cancer grown orthotopically in mice

2012 | Other
Source: Self-asserted source
Donald Yapp

Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model

Journal of controlled release
2012 | Journal article
Source: Self-asserted source
Donald Yapp

RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga

Nuclear medicine and biology
2012 | Journal article
Source: Self-asserted source
Donald Yapp

Abstract B12: The effects of Irinophore C™ on the microenvironment and vasculature of a primary orthotopic model of colorectal cancer.

2011 | Other
Source: Self-asserted source
Donald Yapp

Abstract C235: Interleukin-6 secreted by cancer-associated fibroblasts mediates gemcitabine resistance in pancreatic cancer.

2011 | Other
Source: Self-asserted source
Donald Yapp

Abstract LB-41: Regulation of adhesion, motility, and invasion by insulin-like growth factor-2 binding protein 3 in pancreatic cancer cells

2011 | Other
Source: Self-asserted source
Donald Yapp

Comparison of bifunctional chelates and isotopes for small peptide PET imaging

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
2011 | Conference paper
Source: Self-asserted source
Donald Yapp
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