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Human/mouse CD137 agonist, JNU-0921, effectively shrinks tumors through enhancing the cytotoxicity of CD8 + T cells in cis and in trans

Science Advances
2024-08-23 | Journal article
DOI: 10.1126/sciadv.adp8647
Contributors: Lu Liu; Fenghua Chen; Shan Li; Tong Yang; Shuzhen Chen; Yang Zhou; Zejian Lin; Guandi Zeng; Pengju Feng; Hong-Bing Shu et al.
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Crossref

6‐Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD‐1 to inhibit PD‐1 signalling and enhance T cell function

Immunology
2023-10 | Journal article
DOI: 10.1111/imm.13671
Contributors: Lu Liu; Yuxi Lei; Zongyao Zheng; Xingang Zhou; Shuzhen Chen; Guandi Zeng; Lei Yu; Peng Wang; Liang Chen
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