Personal information

Emails & domains

Verified email domains

Websites & social links

LinkedIn
Lab Website

Other IDs

Scopus Author ID: 59226817600
ResearcherID: P-6326-2018
ResearcherID: ABC-8681-2020
Scopus Author ID: 24074344100

Keywords

acute myeloid leukaemia, stem cells, patient-derived xenografts

Countries

Australia

Biography

Dr Claudia Bruedigam is a Research Scientist with a major interest in blood cancers. She leads the AML Therapeutics Laboratory at the Australian Centre for Blood Diseases, School of Translational Medicine, Monash University, Melbourne, and serves as Honorary Senior Fellow at The University of Queensland, Brisbane, Australia. Claudia currently supervises two research assistants, two PhD students, and two visiting MSc / MD students. Her research group investigates topics at the interface of oncology, immunology and biochemistry with a strong focus on Acute Myeloid Leukaemia (AML), a very aggressive and rapidly fatal blood cancer. Claudia received her PhD in Molecular Medicine from Erasmus University Rotterdam, The Netherlands, in June 2015. Her PhD studies were supported by a competitive European Marie Curie Mobility Fellowship. Since 2019, Claudia has developed her research program with the support of >$1.5M funding from sole chief investigator NHMRC grants, and a Play for a Cure Foundation donation. She has received numerous awards including prestigious ASH Abstract Achievement Awards in 2013, 2016, and 2017, and a Leukaemia Foundation New Investigator Award in 2014. Claudia has demonstrated expertise with a track record of at least 27 peer-reviewed publications including first and corresponding author publications in the top international journals Cell Stem Cell and Nature Cancer.

Activities

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Employment (6)

Monash University: Melbourne, Victoria, AU

2025-03-01 to present | Group Leader (Level C) (Australian Centre for Blood Diseases)
Employment
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute: Brisbane, AU

2024-01-01 to 2025-02-28 | Team Head (Cancer Program)
Employment
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute: Brisbane, AU

2019-03-01 to 2023-12-31 | Senior Research Officer (Cancer Program)
Employment
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute: Brisbane, AU

2015-06-16 to 2019-02-28 | Research Officer (Immunology)
Employment
Source: Self-asserted source
Claudia Bruedigam

Erasmus University Rotterdam: Rotterdam, NL

2010-09-01 to 2015-06-15 | PhD Student (Molecular Medicine)
Employment
Source: Self-asserted source
Claudia Bruedigam

Erasmus MC: Rotterdam, NL

2006-03-01 to 2010-08-31 | Scientific Researcher (Wetenschappelijk Medewerker) (Internal Medicine)
Employment
Source: Self-asserted source
Claudia Bruedigam

Education and qualifications (2)

Erasmus University Rotterdam: Rotterdam, NL

2010-09-01 to 2015-06-15 | PhD (Molecular Medicine)
Education
Source: Self-asserted source
Claudia Bruedigam

University of Potsdam: Potsdam, DE

1999-10-01 to 2005-09-01 | Diplom in Biochemistry (Dipl. Biochem) (Faculty of Mathematics and Natural Sciences)
Education
Source: Self-asserted source
Claudia Bruedigam

Professional activities (20)

QIMR Berghofer Medical Research Institute: Brisbane, AU

2023-01-01 to present | Convenor of the Departmental Haematology Research Seminar Series (Cancer Program)
Service
Source: Self-asserted source
Claudia Bruedigam

University of Queensland: Brisbane, Queensland, AU

2020-11-24 to present | Honorary Senior Fellow (School of Biomedical Sciences)
Invited position
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute Higher Degree Research Committee: Brisbane, AU

2019-04-01 to present | Independent Reviewer
Service
Source: Self-asserted source
Claudia Bruedigam

American Society of Hematology: Washington, DC, US

2018 to present
Membership
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute: Brisbane, AU

2015 to present | Science Ambassador
Service
Source: Self-asserted source
Claudia Bruedigam

German Society of Biochemistry and Molecular Biology: Frankfurt / Main, DE

2005 to present
Membership
Source: Self-asserted source
Claudia Bruedigam

National Health and Medical Research Council: Canberra, Australian Capital Territory, AU

2023-05-22 to 2023-08-01 | Ideas Grant Review Panel Member
Service
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Medical Research Institute Student Society: Brisbane, AU

2022-07-22 to 2022-07-22 | Poster Presentation Judge at the QIMR Berghofer Medical Research Institute Student Symposium
Service
Source: Self-asserted source
Claudia Bruedigam

New Directions in Leukaemia Research Conference: Brisbane, AU

2022-05-30 to 2022-06-01 | Scientific Session Chair
Service
Source: Self-asserted source
Claudia Bruedigam

University of Queensland: Brisbane, AU

2019-10-09 to 2019-10-09 | Poster Presentation Judge at the University of Queensland Medical Student Conference (Faculty of Medicine)
Service
Source: Self-asserted source
Claudia Bruedigam

Queensland University of Technology: Brisbane, QLD, AU

2018-09-28 to 2019-09-30 | Visiting Fellow (School of Biomedical Sciences)
Invited position
Source: Self-asserted source
Claudia Bruedigam

QIMR Berghofer Postdoctoral Association (QPAC): Brisbane, AU

2019-05-31 | Best Poster Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

New Directions in Leukaemia Research Conference: Brisbane, AU

2018-03-25 to 2018-03-28 | Scientific Session Chair at the New Directions in Leukaemia Research Conference
Service
Source: Self-asserted source
Claudia Bruedigam

Biochemistry & Biophysics Reports (Elsevier): Amsterdam, NL

2015-06-16 to 2017-12-31 | Associate Editor
Service
Source: Self-asserted source
Claudia Bruedigam

American Society of Hematology: Washington D.C., District of Columbia, US

2017-11-01 | Abstract Achievement Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

German Stem Cell Network (GSCN): Berlin, DE

2017-07-27 | Travel Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

National Health and Medical Research Council: Canberra, Australian Capital Territory, AU

2016 to 2017 | External Assessor for NHMRC Project Grants
Service
Source: Self-asserted source
Claudia Bruedigam

American Society of Hematology: Washington D.C., District of Columbia, US

2016-10-14 | Abstract Achievement Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

Leukaemia Foundation of Queensland: Brisbane, Queensland, AU

2014-04-01 | New Investigator Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

American Society of Hematology: Washington D.C., District of Columbia, US

2013-10-24 | Abstract Achievement Award
Distinction
Source: Self-asserted source
Claudia Bruedigam

Funding (2)

Targeting Lipid Droplet Homeostasis to Develop Therapies for Acute Myeloid Leukaemia

2023-12-15 to present | Grant
National Health and Medical Research Council (Canberra, AU)
URL: https://app.dimensions.ai/details/grant/grant.13891070
GRANT_NUMBER:

2030175
Source: Self-asserted source
Claudia Bruedigam via DimensionsWizard

Optimising the Efficacy of Imetelstat Therapy in Acute Myeloid Leukaemia

2019-01-01 to present | Grant
National Health and Medical Research Council (Canberra, AU)
URL: https://app.dimensions.ai/details/grant/grant.8538156
GRANT_NUMBER: 1157263
Source: Self-asserted source
Claudia Bruedigam via DimensionsWizard

Works (50 of 72)

Items per page:
Page 1 of 2

Modeling Acute Myeloid Leukemia Using StarPEG-Heparin Hydrogels

Methods in molecular biology (Clifton, N.J.)
2024 | Journal article
DOI: 10.1007/978-1-0716-3674-9_6
EID:

2-s2.0-85185862657

Part of ISSN: 19406029
Contributors: Holloway, P.L.; Ravichandran, A.; Clegg, J.; Bruedigam, C.; Bray, L.J.
Source: Self-asserted source
Claudia Bruedigam via Scopus - Elsevier

Gene Expression Analyses in Models of Rosiglitazone-Induced Physiological and Pathological Mineralization Identify Novel Targets to Improve Bone and Vascular Health

Cells
2023 | Journal article
DOI: 10.3390/cells12202462
EID:

2-s2.0-85175024337

Part of ISSN: 20734409
Contributors: Bruedigam, C.; Leeuwen, J.P.T.M.V.; Peppel, J.V.D.
Source: Self-asserted source
Claudia Bruedigam via Scopus - Elsevier

Oncogenic drivers dictate immune control of acute myeloid leukemia

bioRxiv
2023 | Other
DOI: 10.1101/2023.02.08.527448
EID:

2-s2.0-85152122206

Part of ISSN: 26928205
Contributors: Austin, R.J.; Straube, J.; Halder, R.; Janardhanan, Y.; Bruedigam, C.; Witkowski, M.; Cooper, L.; Porter, A.; Braun, M.; Souza-Fonseca-Guimaraes, F. et al.
Source: Self-asserted source
Claudia Bruedigam via Scopus - Elsevier
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Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia

Nature Cancer
2023-10-30 | Journal article
DOI: 10.1038/s43018-023-00653-5
Contributors: Claudia Bruedigam; Amy H. Porter; Axia Song; Gerjanne Vroeg in de Wei; Thomas Stoll; Jasmin Straube; Leanne Cooper; Guidan Cheng; Vivian F. S. Kahl; Alexander P. Sobinoff et al.
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Crossref
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Telomerase-targeted therapies in myeloid malignancies

Blood Advances
2023-08-22 | Journal article
DOI: 10.1182/bloodadvances.2023009903
Contributors: Julian A. Waksal; Claudia Bruedigam; Rami S. Komrokji; Catriona H. M. Jamieson; John O. Mascarenhas
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Crossref
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Imetelstat-Mediated Alterations in Fatty Acid Metabolism To Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia

2023-04-28 | Preprint
DOI: 10.1101/2023.04.25.538357
Contributors: Claudia Bruedigam; Amy H. Porter; Axia Song; Gerjanne Vroeg in de Wei; Thomas Stoll; Jasmin Straube; Leanne Cooper; Guidan Cheng; Vivian F. S. Kahl; Alexander P. Sobinoff et al.
Source: check_circle
Crossref
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Oncogenic drivers dictate immune control of acute myeloid leukemia.

Nature communications
2023-04-14 | Journal article
DOI: 10.1038/s41467-023-37592-9
PMID: 37059710
PMC: PMC10104832
Contributors: Austin RJ; Jasmin Straube; Halder R; Janardhanan Y; Bruedigam C; Matthew T Witkowski; Cooper L; Porter A; Braun M; Souza-Fonseca-Guimaraes F et al.
Source: Self-asserted source
Claudia Bruedigam
grade
Preferred source (of 3)‎

Data from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.c.6549562
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Data from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.c.6549562.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Figure from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541194
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
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Crossref

Supplementary Figure from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541194.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541182
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541185
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541179.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541176.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541170.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541188
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541179
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541173.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
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Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541182.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
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Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541191
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541170
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541188.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541164.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541167.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541191.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541185.v1
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541176
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541164
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541167
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
Source: check_circle
Crossref

Supplementary Table from Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

2023-04-04 | Preprint
DOI: 10.1158/2159-8290.22541173
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
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Crossref

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.

Leukemia
2023-02-04 | Journal article
DOI: 10.1038/s41375-023-01832-0
PMID: 36739348
PMC: PMC10079527
Contributors: Jasmin Straube; Eifert T; Therese Vu; Janardhanan Y; Haldar R; von Eyss B; Cooper L; Bruedigam C; Victoria Y. Ling; Cooper E et al.
Source: Self-asserted source
Claudia Bruedigam
grade
Preferred source (of 4)‎

Imetelstat-Mediated Alterations in Lipid Metabolism to Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia

Blood
2022 | Journal article
DOI: 10.1182/BLOOD-2022-168166
WOSUID: WOS:000893223200202
Contributors: Bruedigam, Claudia; Porter, Amy H.; Song, Axia; de Wei, Gerjanne Vroeg In; Stoll, Thomas; Straube, Jasmin; Cooper, Leanne T.; Cheng, Guidan; Kahl, Vivian F. S.; Sobinoff, Alexander et al.
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Web of Science Researcher Profile Sync

Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.

Leukemia
2022-11-18 | Journal article
DOI: 10.1038/s41375-022-01755-2
PMID: 36400926
Contributors: Victoria Y. Ling; Jasmin Straube; Godfrey W; Haldar R; Janardhanan Y; Cooper L; Bruedigam C; Cooper E; Paniz Tavakoli Shirazi; Sebastien Jacquelin et al.
Source: Self-asserted source
Claudia Bruedigam
grade
Preferred source (of 3)‎

Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

Cancer Discovery
2022-06-02 | Journal article
DOI: 10.1158/2159-8290.CD-20-1145
Contributors: Jessica M. Salmon; Izabela Todorovski; Kym L. Stanley; Claudia Bruedigam; Conor J. Kearney; Luciano G. Martelotto; Fernando Rossello; Timothy Semple; Gisela Mir Arnau; Magnus Zethoven et al.
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Crossref
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Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid Leukemia

Blood
2021 | Journal article
DOI: 10.1182/BLOOD-2021-148379
WOSUID: WOS:000736413900236
Contributors: Ling, Victoria Y.; Jacquelin, Sebastien; Straube, Jasmin; Haldar, Rohit; Janardhanan, Yashaswini; Cooper, Leanne T.; Bruedigam, Claudia; Cooper, Emily; Godfrey, William; Tey, Siok-Keen et al.
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Web of Science Researcher Profile Sync

Intact TP53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.

Blood
2021-04-06 | Journal article
DOI: 10.1182/blood.2020010167
PMID: 33824975
Source: Self-asserted source
Claudia Bruedigam
grade
Preferred source (of 2)‎

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

Leukemia
2020 | Journal article
DOI: 10.1038/S41375-019-0638-Y
WOSUID: WOS:000522798800010
Contributors: Austin, Rebecca J.; Straube, Jasmin; Bruedigam, Claudia; Pali, Gabor; Jacquelin, Sebastien; Vu, Therese; Green, Joanne; Graesel, Julius; Lansink, Lianne; Cooper, Leanne et al.
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Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

Nature Communications
2020 | Journal article
DOI: 10.1038/S41467-020-16840-2
WOSUID: WOS:000558685500013
Contributors: Vu, Therese; Straube, Jasmin; Porter, Amy H.; Bywater, Megan; Song, Axia; Ling, Victoria; Cooper, Leanne; Pali, Gabor; Bruedigam, Claudia; Jacquelin, Sebastien et al.
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GENERATION OF A COMPREHENSIVE PATIENT-DERIVED XENOGRAFT RESOURCE AS TOOL FOR ADEQUATELY POWERED PHASE II-LIKE PRECLINICAL TRIALS IN ACUTE MYELOID LEUKEMIA

Experimental Hematology
2019 | Journal article
WOSUID: WOS:000844545400107
Contributors: Bruedigam, Claudia; Porter, Amy; Song, Axia; Cooper, Leanne; Straube, Jasmin; Hartel, Gunter; Lane, Steven
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IDENTIFICATION OF GENETIC PATHWAYS CONTROLLING RESISTANCE TO STANDARD COMBINATION CHEMOTHERAPY IN ACUTE MYELOID LEUKAEMIA

Experimental Hematology
2019 | Journal article
WOSUID: WOS:000844545400158
Contributors: Ling, Victoria; Godfrey, William; Jacquelin, Sebastien; Straube, Jasmin; Cooper, Leanne; Bruedigam, Claudia; Tey, Siok-Keen; Bullinger, Lars; Herold, Marco; Bywater, Megan et al.
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Loss of Phospholipase C Gamma 1 (PLCG1) Impairs AML1-ETO Induced Leukemia Stem Cell Self-Renewal

Blood
2019 | Journal article
DOI: 10.1182/BLOOD-2019-121996
WOSUID: WOS:000518218500361
Contributors: Schnoeder, Tina M.; Schwarzer, Adrian; Perner, Florian; Kirkpatrick, Joanna; Dolnik, Anna; Doehner, Konstanze; Arreba-Tutusaus, Patricia; Assi, Salam A.; Bruedigam, Claudia; Kathner, Carolin et al.
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Identification of Genetic Pathways Controlling Resistance to Standard Combination Chemotherapy in Acute Myeloid Leukemia

Blood
2018 | Journal article
DOI: 10.1182/BLOOD-2018-99-115729
WOSUID: WOS:000454837608033
Contributors: Ling, Victoria Y.; Godfrey, William; Jacquelin, Sebastien; Straube, Jasmin; Cooper, Leanne T.; Bruedigam, Claudia; Tey, Siok-Keen; Bullinger, Lars; Herold, Marco J.; Bywater, Megan et al.
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Integrated Molecular Analysis Identifies Replicative Stress As Sensitizer to Imetelstat Therapy in AML

Blood
2017 | Journal article
WOSUID: WOS:000432419402048
Contributors: Bruedigam, Claudia; Porter, Amy H.; Wackrow, Brad; Straube, Jasmin; Cooper, Leanne T.; Song, Axia; Lee, Stanley Chun-Wei; Abdel-Wahab, Omar; Hill, Geoffrey R.; Lane, Steven W.
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Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

Haematologica
2017-05 | Journal article
DOI: 10.3324/haematol.2017.166389
Part of ISSN: 0390-6078
Contributors: Amy H. Porter; Lucie Leveque-El Mouttie; Therese Vu; Claudia Bruedigam; Joanne Sutton; Sebastien Jacquelin; Geoffrey R. Hill; Kelli P.A. MacDonald; Steven W. Lane
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Crispr-Cas9 Mediated Disruption of Dnmt3a in JakV617F Hematopoietic Stem Cells Accelerates Disease Phenotype and Induces Lethal Myelofibrosis

Blood
2016 | Journal article
DOI: 10.1182/BLOOD.V128.22.794.794
WOSUID: WOS:000394446804137
Contributors: Jacquelin, Sebastien; Dishington, Emma; Vu, Therese; Song, Axia; Heidecker, Matthew; Guignes, Solene; Bruedigam, Claudia; Sutton, Joanne; Hill, Geoffrey R.; Cloonan, Nicole et al.
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The Preclinical Efficacy of a Novel Telomerase Inhibitor, Imetelstat, in AML - a Randomized Trial in Patient-Derived Xenografts

Blood
2016 | Journal article
DOI: 10.1182/BLOOD.V128.22.578.578
WOSUID: WOS:000394446802070
Contributors: Bruedigam, Claudia; Wackrow, Brad; Song, Axia; Porter, Amy H.; Lee, Stanley Chun-Wei; Moore, Andrew S.; Abdel-Wahab, Omar; Lane, Steven W.
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Telomerase in hematologic malignancies

Current Opinion in Hematology
2016-07 | Journal article
DOI: 10.1097/moh.0000000000000252
Part of ISSN: 1065-6251
Contributors: Claudia Bruedigam; Steven W. Lane
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Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling

Genomics Data
2016-03 | Journal article
DOI: 10.1016/j.gdata.2016.01.014
Part of ISSN: 2213-5960
Contributors: Frederik Otzen Bagger; Claudia Bruedigam; Steven W. Lane
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Cdx2 Cooperates with Flt3-ITD to Induce Acute Myeloid Leukaemia in Mice

Blood
2015 | Journal article
DOI: 10.1182/BLOOD.V126.23.557.557
WOSUID: WOS:000368019001303
Contributors: Vu, Therese; Bruedigam, Claudia; Song, Axia; Guignes, Solene; Austin, Rebecca; Jacquelin, Sebastien; Chalk, Alistair; Walkley, Carl; Scholl, Claudia; Froehling, Stefan et al.
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Peer review (12 reviews for 7 publications/grants)

Review activity for Biomaterials. (1)
Review activity for Cardiovascular diabetology (1)
Review activity for Cell death and disease. (5)
Review activity for Frontiers in oncology. (1)
Review activity for Haematologica. (2)
Review activity for Hematology. (1)
Review activity for Nucleic acids research. (1)
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