Personal information

Human stem cells, Lung development, Human lung models, Cystic fibrosis, Disease modelling, Personalized medicine, Regenerative Medicine
Canada

Activities

Employment (4)

University of Toronto: Toronto, Ontario, CA

2019-08-01 to present | Assistant Professor (Laboratory Medicine & Pathobiology)
Employment
Source: Self-asserted source
Amy Wong

Hospital for Sick Children: Toronto, Ontario, CA

2019-03-18 to present | Scientist (Developmental & Stem Cell Biology)
Employment
Source: Self-asserted source
Amy Wong

Hospital for Sick Children: Toronto, Ontario, CA

2016-06-01 to 2019-03-15 | Senior Research Associate (Developmental & Stem Cell Biology)
Employment
Source: Self-asserted source
Amy Wong

Hospital for Sick Children: Toronto, ON, CA

2009-04-06 to 2016-05-31 | Post-doctoral fellow (Developmental & Stem Cell Biology)
Employment
Source: Self-asserted source
Amy Wong

Education and qualifications (2)

University of Toronto: Toronto, ON, CA

2004-09-01 to 2008-11-01 | Ph.D (Medical Sciences)
Education
Source: Self-asserted source
Amy Wong

University of Toronto: Toronto, ON, CA

2001-09-01 to 2003-06-01 | M.Sc (Laboratory Medicine & Pathobiology)
Education
Source: Self-asserted source
Amy Wong

Works (26)

Tunable In Situ Synthesis of Ultrathin Extracellular Matrix‐Derived Membranes in Organ‐on‐a‐Chip Devices

Advanced Healthcare Materials
2024-08 | Journal article
Contributors: Jeremy D. Newton; Yuetong Song; Siwan Park; Kayshani R. Kanagarajah; Amy P. Wong; Edmond W. K. Young
Source: check_circle
Crossref

Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity.

Nature communications
2024-07-13 | Journal article | Author
Contributors: Henry Quach; Farrell S; Ming Jia Michael Wu; Kanagarajah K; Leung JW; Xu X; Kallurkar P; Turinsky AL; Bear CE; Ratjen F et al.
Source: Self-asserted source
Amy Wong

Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity

2023-11-28 | Preprint
Contributors: Amy Wong; Henry Quach*; Spencer Farrell*; Kayshani Kanagarajah; Michael Wu; Xiaoqiao Xu; Prajkta Kallurkar; Andrei Turinsky; Christine Bear; Felix Ratjen et al.
Source: check_circle
Crossref

Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.

Current protocols
2022-01-01 | Journal article
Source: Self-asserted source
Amy Wong

Gene therapy for cystic fibrosis: new tools for precision medicine

Journal of Translational Medicine
2021-12 | Journal article
Contributors: Jin-A Lee; Alex Cho; Elena N. Huang; Yiming Xu; Henry Quach; Jim Hu; Amy P. Wong
Source: check_circle
Crossref

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients.

Stem cell reports
2021-10-21 | Journal article
Source: Self-asserted source
Amy Wong

A Developmental Role of the Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Lung Disease Pathogenesis.

Frontiers in cell and developmental biology
2021-10-11 | Journal article
Source: Self-asserted source
Amy Wong

Modeling lung cell development using human pluripotent stem cells

[]
2021-07-16 | Preprint
Source: Self-asserted source
Amy Wong

Conversion of human and mouse fibroblasts into lung-like epithelial cells.

Scientific reports
2019-06-21 | Journal article
Source: Self-asserted source
Amy Wong
grade
Preferred source (of 2)‎

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.

NPJ genomic medicine
2017-04-01 | Journal article
Source: Self-asserted source
Amy Wong

Bone marrow cells expressing clara cell secretory protein increase epithelial repair after ablation of pulmonary clara cells.

Molecular therapy : the journal of the American Society of Gene Therapy
2013-04-23 | Journal article
Source: Self-asserted source
Amy Wong

Cell-based tissue engineering for lung regeneration.

American journal of physiology. Lung cellular and molecular physiology
2006-10-06 | Journal article
Source: Self-asserted source
Amy Wong

Airway regeneration: the role of the Clara cell secretory protein and the cells that express it.

Journal article
Source: Self-asserted source
Amy Wong

Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.

Journal article
Source: Self-asserted source
Amy Wong

Depletion of bone marrow CCSP-expressing cells delays airway regeneration.

Journal article
Source: Self-asserted source
Amy Wong

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein.

Journal article
Source: Self-asserted source
Amy Wong

Effects of intravascular cryotherapy on vessel wall repair in a balloon-injured rabbit iliac artery model.

Journal article
Source: Self-asserted source
Amy Wong

Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.

Journal article
Source: Self-asserted source
Amy Wong

Expansive remodeling in venous bypass grafts: novel implications for vein graft disease.

Journal article
Source: Self-asserted source
Amy Wong

Generation of Lung Epithelium from Pluripotent Stem Cells.

Journal article
Source: Self-asserted source
Amy Wong

Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium.

Journal article
Source: Self-asserted source
Amy Wong

In vitro differences between venous and arterial-derived smooth muscle cells: potential modulatory role of decorin.

Journal article
Source: Self-asserted source
Amy Wong

Optimization of targeted cell replacement therapy: a new approach for lung disease.

Journal article
Source: Self-asserted source
Amy Wong

Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.

Journal article
Source: Self-asserted source
Amy Wong

Targeted cell replacement with bone marrow cells for airway epithelial regeneration.

Journal article
Source: Self-asserted source
Amy Wong

The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.

Journal article
Source: Self-asserted source
Amy Wong

Peer review (10 reviews for 8 publications/grants)

Review activity for Cell & bioscience. (1)
Review activity for EBioMedicine. (2)
Review activity for EMBO reports. (1)
Review activity for Journal of cystic fibrosis. (1)
Review activity for JoVE. (1)
Review activity for Life science alliance. (1)
Review activity for Nature biotechnology. (1)
Review activity for Nature communications (2)