Personal information

Activities

Employment (1)

Klinikum der Universität München: Munchen, Bayern, DE

2021-03-01 to present | Principal Investigator (Institute for Stroke and Dementia Research)
Employment
Source: Self-asserted source
Sarah Jäkel

Works (17)

Are oligodendrocytes bystanders or drivers of Parkinson’s disease pathology?

PLOS Biology
2025-01-08 | Journal article
Contributors: José María Salazar Campos; Lena F. Burbulla; Sarah Jäkel
Source: check_circle
Crossref

Impact of fixation duration on messenger RNA detectability in human formalin-fixed paraffin-embedded brain tissue

Brain Communications
2024-10-30 | Journal article
Contributors: Charlene-Annett Hurler; Sabine Liebscher; Thomas Arzberger; Sarah Jäkel
Source: check_circle
Crossref

Mapping the glial transcriptome in Huntington’s disease using snRNAseq: Selective disruption of glial signatures across brain regions

2022-09-10 | Preprint
Contributors: Sunniva M. K. Bøstrand; Luise A. Seeker; Nina-Lydia Kazakou; Nadine Bestard-Cuche; Sarah Jäkel; Boyd Kenkhuis; Neil C. Henderson; Susanne T. de Bot; Willeke van Roon-Mom; Josef Priller et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Single nuclei RNAseq stratifies multiple sclerosis patients into distinct white matter glial responses

2022-04-09 | Preprint
Contributors: Will Macnair; Daniela Calini; Eneritz Agirre; Julien Bryois; Sarah Jäkel; Petra Kukanja; Nadine Stokar; Virginie Ott; Lynette C. Foo; Ludovic Collin et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Marked regional glial heterogeneity in the human white matter of the central nervous system

2022-03-25 | Preprint
Contributors: Luise A. Seeker; Nadine Bestard-Cuche; Sarah Jäkel; Nina-Lydia Kazakou; Sunniva M. K. Bøstrand; Alastair M. Kilpatrick; David Van Bruggen; Mukund Kabbe; Fabio Baldivia Pohl; Zahra Moslehi et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

NG2-Glia Transiently Overcome Their Homeostatic Network and Contribute to Wound Closure After Brain Injury

Frontiers in Cell and Developmental Biology
2021-04-27 | Journal article
Part of ISSN: 2296-634X
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

What Have Advances in Transcriptomic Technologies Taught us About Human White Matter Pathologies?

Frontiers in Cellular Neuroscience
2020-08-04 | Journal article
Part of ISSN: 1662-5102
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulphate production

eLife
2020-06-09 | Journal article
Part of ISSN: 2050-084X
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Altered human oligodendrocyte heterogeneity in multiple sclerosis

Nature
2019 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

Nature Medicine
2018-12 | Journal article
Contributors: Ana Mendanha Falcão; David van Bruggen; Sueli Marques; Mandy Meijer; Sarah Jäkel; Eneritz Agirre; Samudyata; Elisa M. Floriddia; Darya P. Vanichkina; Charles ffrench-Constant et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.

Science translational medicine
2017-12-01 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Glial Cells and Their Function in the Adult Brain: A Journey through the History of Their Ablation.

Frontiers in Cellular Neuroscience
2017-02-13 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells

Glia
2016 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control.

Cell metabolism
2016-05-01 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury.

Glia
2015-10-14 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.

Glia
2015-08-06 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy.

Molecular pharmaceutics
2015-04-10 | Journal article
Source: Self-asserted source
Sarah Jäkel
grade
Preferred source (of 2)‎

Peer review (9 reviews for 6 publications/grants)

Review activity for Acta neuropathologica communications. (2)
Review activity for Nature aging. (1)
Review activity for Nature communications (3)
Review activity for PLoS biology. (1)
Review activity for Scientific data. (1)
Review activity for Stem cell reports. (1)