Personal information

Verified email addresses

Verified email domains

Mechanobiology, Cancer research, Cancer metastasis, Cancer diagnosis and prognosis, Wound healing and prevention
Israel, Israel

Activities

Employment (4)

Technion – Israel Institute of Technology: Haifa, IL

Employment
Source: check_circle
Technion - Israel Institute of Technology

Technion Israel Institute of Technology: Haifa, Haifa, IL

2018-04-01 to present | Associate Professor (Biomedical Engineering)
Employment
Source: Self-asserted source
Daphne Weihs

Technion Israel Institute of Technology: Haifa, Haifa, IL

2006-10 to 2018-03-31 | Assistant Professor (Tenured) (Biomedical Engineering)
Employment
Source: Self-asserted source
Daphne Weihs

University of California Los Angeles: Los Angeles, CA, US

2004-01 to 2006-06 | post-graduate researcher (Pathology and lab medicine)
Employment
Source: Self-asserted source
Daphne Weihs

Education and qualifications (3)

Technion Israel Institute of Technology: Haifa, Haifa, IL

2000-10 to 2004-02 | PhD (Chemical Engineering)
Education
Source: Self-asserted source
Daphne Weihs

Technion Israel Institute of Technology: Haifa, Haifa, IL

1998-10 to 2000-09 | MSc (Chemical Engineering)
Education
Source: Self-asserted source
Daphne Weihs

Technion Israel Institute of Technology: Haifa, Haifa, IL

1994-10 to 1998-08 | BSc (Chemical Engineering)
Education
Source: Self-asserted source
Daphne Weihs

Works (50 of 74)

Items per page:
Page 1 of 2

Chemotherapy-Induced Cell-Surface GRP78 Expression as a Prognostic Marker for Invasiveness of Metastatic Triple-Negative Breast Cancer

Annals of Biomedical Engineering
2025-01-05 | Journal article
Contributors: Martha B. Alvarez-Elizondo; Annat Raiter; Rinat Yerushalmi; Daphne Weihs
Source: check_circle
Crossref

Mechanobiological cell adaptations to changing microenvironments determine cancer invasiveness: Experimentally validated finite element modeling

Journal of Biomedical Materials Research Part A
2023-12 | Journal article
Contributors: Marina Tulchinsky; Daphne Weihs
Source: check_circle
Crossref

Computational modeling reveals a vital role for proximity-driven additive and synergistic cell-cell interactions in increasing cancer invasiveness

Acta Biomaterialia
2023-06 | Journal article
Contributors: Marina Tulchinsky; Daphne Weihs
Source: check_circle
Crossref

Physical confinement and cell proximity increase cell migration rates and invasiveness: A mathematical model of cancer cell invasion through flexible channels

Journal of the Mechanical Behavior of Biomedical Materials
2023-06 | Journal article
Contributors: Qiyao Peng; Fred J. Vermolen; Daphne Weihs
Source: check_circle
Crossref

Breast cancer stem cells: mechanobiology reveals highly invasive cancer cell subpopulations

Cellular and Molecular Life Sciences
2022-03 | Journal article
Contributors: Martha B. Alvarez-Elizondo; Daphne Weihs
Source: check_circle
Crossref

Mechanical interactions of invasive cancer cells through their substrate evolve from additive to synergistic

Journal of Biomechanics
2021-12 | Journal article
Contributors: Guy I. Wiener; Dana Kadosh; Daphne Weihs
Source: check_circle
Crossref

Rapid, quantitative prediction of tumor invasiveness in non-melanoma skin cancers using mechanobiology-based assay

Biomechanics and Modeling in Mechanobiology
2021-10-12 | Journal article
Contributors: Sally Kortam; Yulia Merkher; Aviv Kramer; Issa Metanes; Dean Ad-El; Judit Krausz; Yaron Har-Shai; Daphne Weihs
Source: check_circle
Crossref

Machine-Learning Provides Patient-Specific Prediction of Metastatic Risk Based on Innovative, Mechanobiology Assay

Annals of Biomedical Engineering
2021-07-22 | Journal article
Contributors: Rakefet Rozen; Daphne Weihs
Source: check_circle
Crossref

Modeling force application configurations and morphologies required for cancer cell invasion

Biomechanics and Modeling in Mechanobiology
2021-06-08 | Journal article
Contributors: Yaniv Ben-David; Daphne Weihs
Source: check_circle
Crossref

Actin as a Target to Reduce Cell Invasiveness in Initial Stages of Metastasis

Annals of Biomedical Engineering
2021-05-03 | Journal article
Contributors: Martha B. Alvarez-Elizondo; Yulia Merkher; Gal Shleifer; Carmel Gashri; Daphne Weihs
Source: check_circle
Crossref

A Cellular Automata Model of Oncolytic Virotherapy in Pancreatic Cancer

Bulletin of Mathematical Biology
2020 | Journal article
EID:

2-s2.0-85088836785

Part of ISBN:

15229602 00928240

Contributors: Chen, J.; Weihs, D.; Vermolen, F.J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Computational modeling of therapy on pancreatic cancer in its early stages

Biomechanics and Modeling in Mechanobiology
2020 | Journal article
EID:

2-s2.0-85073936899

Part of ISBN:

16177940 16177959

Contributors: Chen, J.; Weihs, D.; Vermolen, F.J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Two- and three-dimensional de-drifting algorithms for fiducially marked image stacks

Journal of Biomechanics
2020 | Journal article
EID:

2-s2.0-85088381820

Part of ISBN:

18732380 00219290

Contributors: Wiener, G.I.; Kadosh, D.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Rapid Cancer Diagnosis and Early Prognosis of Metastatic Risk Based on Mechanical Invasiveness of Sampled Cells

Annals of Biomedical Engineering
2020-12-15 | Journal article
Contributors: Y. Merkher; Y. Horesh; Z. Abramov; G. Shleifer; O. Ben-Ishay; Y. Kluger; D. Weihs
Source: check_circle
Crossref

Lung mechanics modifications facilitating metastasis are mediated in part by breast cancer‐derived extracellular vesicles

International Journal of Cancer
2020-11-15 | Journal article
Contributors: Tamar Barenholz‐Cohen; Yulia Merkher; Jozafina Haj; Dvir Shechter; Daniela Kirchmeier; Yuval Shaked; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Finite element analysis reveals an important role for cell morphology in response to mechanical compression

Biomechanics and Modeling in Mechanobiology
2020-06-14 | Journal article
Contributors: Mayssam Saeed; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Micropatterned topographies reveal measurable differences between cancer and benign cells

Medical Engineering & Physics
2020-01 | Journal article
Contributors: Martha B. Alvarez-Elizondo; Ching Wen Li; Anat Marom; Yen-Ting Tung; Gilad Drillich; Yam Horesh; Shu Ching Lin; Gou-Jen Wang; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Bioengineering studies of cell migration in wound research

Innovations and Emerging Technologies in Wound Care
2019 | Book chapter
EID:

2-s2.0-85082477836

Contributors: Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Computational cell-based modeling and visualization of cancer development and progression

Lecture Notes in Computational Vision and Biomechanics
2019 | Book chapter
EID:

2-s2.0-85070004615

Part of ISBN:

22129413 22129391

Contributors: Chen, J.; Weihs, D.; Vermolen, F.J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Traction force microscopy in differentiating cells

Computational Methods in Applied Sciences
2019 | Book chapter
EID:

2-s2.0-85064674727

Part of ISBN:

18713033

Contributors: Abuhattum, S.; Gefen, A.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Sodium pyruvate pre‐treatment prevents cell death due to localised, damaging mechanical strains in the context of pressure ulcers

International Wound Journal
2019-10 | Journal article
Contributors: Martha B. Alvarez‐Elizondo; Tamar Barenholz‐Cohen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Non-damaging stretching combined with sodium pyruvate supplement accelerate migration of fibroblasts and myoblasts during gap closure

Clinical Biomechanics
2019-02 | Journal article
Contributors: Anat Marom; Yulia Berkovitch; Samer Toume; Martha B. Alvarez-Elizondo; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A model for cell migration in non-isotropic fibrin networks with an application to pancreatic tumor islets

Biomechanics and Modeling in Mechanobiology
2018 | Journal article
EID:

2-s2.0-85030860773

Part of ISBN:

16177940 16177959

Contributors: Chen, J.; Weihs, D.; Vermolen, F.J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

A particle finite element-based framework for differentiation paths of stem cells to myocytes and adipocytes: Hybrid cell-based and finite element modeling

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes
2018 | Book chapter
EID:

2-s2.0-85041992750

Contributors: Vermolen, F.J.; Harrevelt, S.D.; Gefen, A.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

A phenomenological model for cell and nucleus deformation during cancer metastasis

Biomechanics and Modeling in Mechanobiology
2018 | Journal article
EID:

2-s2.0-85047664641

Part of ISBN:

16177940 16177959

Contributors: Chen, J.; Weihs, D.; Van Dijk, M.; Vermolen, F.J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Effect of natural honey treatment and external stretching on kinematics of cell migration during gap closure

Lecture Notes in Bioengineering
2018 | Book chapter
EID:

2-s2.0-85062914680

Part of ISBN:

21952728 2195271X

Contributors: Berkovitch, Y.; Toume, S.; Gefen, A.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Mechanobiology of metastatic cancer

Mechanobiology in Health and Disease
2018 | Book chapter
EID:

2-s2.0-85074330214

Contributors: Alvarez-Elizondo, M.B.; Rozen, R.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Proximity of metastatic cells strengthens the mechanical interaction with their environment

Lecture Notes in Bioengineering
2018 | Book chapter
EID:

2-s2.0-85062904319

Part of ISBN:

21952728 2195271X

Contributors: Merkher, Y.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Contemporary oncology research: a special issue on the mechanobiology and biophysics of cancer development and progression

Convergent Science Physical Oncology
2018-01-08 | Journal article
Contributors: Daphne Weihs
Source: check_circle
Crossref

Cell-Gel Mechanical Interactions as an Approach to Rapidly and Quantitatively Reveal Invasive Subpopulations of Metastatic Cancer Cells

Tissue Engineering - Part C: Methods
2017 | Journal article
EID:

2-s2.0-85016089629

Part of ISBN:

19373392 19373384

Contributors: Alvarez-Elizondo, M.B.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Complex, Dynamic Behavior of Extremely Asymmetric Di-n-Alkylphosphate-Anion Aggregates, the Long-Chain Effect and the Role of a Limiting Size: Cryo-TEM, SANS, and X-Ray Diffraction Studies

Journal of Physical Chemistry B
2017 | Journal article
EID:

2-s2.0-85020199488

Part of ISBN:

15205207 15206106

Contributors: Weihs, D.; Kesselman, E.; Schmidt, J.; Talmon, Y.; Sasuga, S.; Fujita, T.; Izawa, K.-I.; O'Connor, C.J.; Okabayashi, H.-F.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Control of cell proliferation by a porous chitosan scaffold with multiple releasing capabilities

Science and Technology of Advanced Materials
2017 | Journal article
EID:

2-s2.0-85037038083

Part of ISBN:

18785514 14686996

Contributors: Cai, S.-J.; Li, C.-W.; Weihs, D.; Wang, G.-J.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Taxol reduces synergistic, mechanobiological invasiveness of metastatic cells

Convergent Science Physical Oncology
2017-11-29 | Journal article
Contributors: Yulia Merkher; Martha B Alvarez-Elizondo; Daphne Weihs
Source: check_circle
Crossref

Low‐level stretching accelerates cell migration into a gap

International Wound Journal
2017-08 | Journal article
Contributors: Samer Toume; Amit Gefen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Metastatic breast cancer cells adhere strongly on varying stiffness substrates, initially without adjusting their morphology

Biomechanics and Modeling in Mechanobiology
2017-06-22 | Journal article
Contributors: Sonbula Massalha; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Proximity of Metastatic Cells Enhances Their Mechanobiological Invasiveness

Annals of Biomedical Engineering
2017-06-21 | Journal article
Contributors: Yulia Merkher; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A phase-contrast microscopy-based method for modeling the mechanical behavior of mesenchymal stem cells

Computer Methods in Biomechanics and Biomedical Engineering
2016 | Journal article
EID:

2-s2.0-84958034328

Contributors: Saeed, M.; Sharabani-Yosef, O.; Weihs, D.; Gefen, A.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Review on experiment-based two- and three-dimensional models for wound healing

Interface Focus
2016-10-06 | Journal article
Contributors: Daphne Weihs; Amit Gefen; Fred J. Vermolen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Asymmetry in traction forces produced by migrating preadipocytes is bounded to 33%

Medical Engineering & Physics
2016-09 | Journal article
Contributors: Shada Abuhattum; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Cytoskeleton and plasma-membrane damage resulting from exposure to sustained deformations: A review of the mechanobiology of chronic wounds

Medical Engineering & Physics
2016-09 | Journal article
Contributors: Amit Gefen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Modern cell biomechanics: A special issue on motility and dynamics of living cells in health, disease and healing

Journal of Biomechanics
2016-05 | Journal article
Contributors: Amit Gefen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Printable low-cost, sustained and dynamic cell stretching apparatus

Journal of Biomechanics
2016-05 | Journal article
Contributors: Samer Toume; Amit Gefen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Mechanical cytoprotection: A review of cytoskeleton-protection approaches for cells

Journal of Biomechanics
2016-05-01 | Journal article
Contributors: Amit Gefen; Daphne Weihs
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Effects of particle uptake, encapsulation, and localization in cancer cells on intracellular applications

Medical Engineering and Physics
2015 | Journal article
EID:

2-s2.0-84928203417

Contributors: Gal, N.; Massalha, S.; Samuelly-Nafta, O.; Weihs, D.
Source: Self-asserted source
Daphne Weihs via Scopus - Elsevier

Mechanical Interaction of Metastatic Cancer Cells with a Soft Gel

Procedia IUTAM
2015 | Journal article
Contributors: Revital Kristal-Muscal; Liron Dvir; Ma’ayan Schvartzer; Daphne Weihs
Source: Self-asserted source
Daphne Weihs via Crossref Metadata Search
grade
Preferred source (of 3)‎

Ratio of total traction force to projected cell area is preserved in differentiating adipocytes

Integr. Biol.
2015 | Journal article
Contributors: Shada Abuhattum; Amit Gefen; Daphne Weihs
Source: Self-asserted source
Daphne Weihs via Crossref Metadata Search
grade
Preferred source (of 3)‎

Embryonic stem cells growing in 3-dimensions shift from reliance on the substrate to each other for mechanical support

Journal of Biomechanics
2015-07 | Journal article
Contributors: Ailing Teo; Mayasari Lim; Daphne Weihs
Source: Self-asserted source
Daphne Weihs via Crossref Metadata Search
grade
Preferred source (of 4)‎

Quantitative measures to reveal coordinated cytoskeleton-nucleus reorganization during in vitro invasion of cancer cells

New J. Phys.
2015-04-01 | Journal article
Contributors: Liron Dvir; Ronen Nissim; Martha B Alvarez-Elizondo; Daphne Weihs
Source: Self-asserted source
Daphne Weihs via Crossref Metadata Search
grade
Preferred source (of 3)‎

Towards a Mathematical Formalism for Semi-stochastic Cell-Level Computational Modeling of Tumor Initiation.

2015-02 | Journal article
Contributors: Vermolen FJ; Meijden RP; Es MV; Gefen A; Weihs D
Source: Self-asserted source
Daphne Weihs via Europe PubMed Central
grade
Preferred source (of 3)‎

Flexible blade for in-line measurement of low-range viscosity

Chemical Engineering Science
2013 | Journal article
WOSUID:

WOS:000315531000016

Contributors: Weihs, Daphne; Hadad, Tal; Gurka, Roi; Liberzon, Alex
Source: Self-asserted source
Daphne Weihs via ResearcherID
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2

Peer review (4 reviews for 3 publications/grants)

Review activity for Biomechanics and modeling in mechanobiology. (2)
Review activity for Journal of mathematical biology. (1)
Review activity for PloS one. (1)