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Biography

Reflecting on my scientific career so far, I recognize that impassioned scientific learning has been the motivating force. My passion for scientific learning was instilled in me by several mentors, whose enthusiasm and devotion cultivated my interest in research and biology. Two such mentors include my research and thesis advisor in college, Dr. Jennifer Wolff, as well as my previous PI, Dr. Jason Tennessen. Dr. Wolff welcomed me into her lab as a sophomore. In her lab, I was taught principles and concepts at the bench that afforded me success in my major and senior thesis. After gaining this research experience, I became more interested in pursuing a career in science, so I accepted an offer as a Research Associate in Dr. Tennessen’s lab at Indiana University. During my three years in the Tennessen lab, I not only learned many new technical skills, I was also encouraged to expand my teaching interests by mentoring students and becoming involved with various STEM education opportunities and student groups. Both mentors recognized my scientific potential and emboldened my desire to continue in academia by showing passion in their mentorship. As a doctoral student in Dr. Anita Corbett’s lab, I focused my passion of mentorship into a career goal of becoming a faculty member at an undergraduate institute, focusing on STEM pedagogy and research-based teaching methods. My thesis project investigated the molecular consequences of disease-linked amino acid substitutions in the conserved RNA processing molecular machine, the RNA exosome. In addition to the skills I developed as an independent scientist, my thesis work also afforded me opportunities to enhance my career goals. Currently I know am an IRACDA fellow at Tufts Medical School, continuing to build my pedagogical skillset.

Activities

Funding (1)

A Budding Yeast Model for Human Disease-Mutations in the RNA Exosome

2020-05-01 to 2023-04-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: F31GM134649
Source: Self-asserted source
Maria C. Sterrett via DimensionsWizard

Works (9)

Comparative analyses of disease-linked missense mutations in the RNA exosome modeled in budding yeast reveal distinct functional consequences in translation

2023-10-19 | Preprint
Contributors: Maria C. Sterrett; Lauryn A. Cureton; Lauren N. Cohen; Ambro van Hoof; Sohail Khoshnevis; Milo B. Fasken; Anita H. Corbett; Homa Ghalei
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Crossref

Hox proteins interact to pattern neuronal subtypes in Caenorhabditis elegans males

Genetics
2022-04-04 | Journal article
Contributors: Andrea K Kalis; Maria C Sterrett; Cecily Armstrong; Amarantha Ballmer; Kylie Burkstrand; Elizabeth Chilson; Estee Emlen; Emma Ferrer; Seanna Loeb; Taylor Olin et al.
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Crossref

A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex

RNA
2021-09 | Journal article
Contributors: Maria C. Sterrett; Liz Enyenihi; Sara W. Leung; Laurie Hess; Sarah E. Strassler; Daniela Farchi; Richard S. Lee; Elise S. Withers; Isaac Kremsky; Richard E. Baker et al.
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Crossref

A Budding Yeast Model for Human Disease Mutations in theEXOSC2Cap Subunit of the RNA Exosome

2020-12-07 | Preprint
Contributors: Maria C. Sterrett; Liz Enyenihi; Sara W. Leung; Laurie Hess; Sarah E. Strassler; Daniela Farchi; Richard S. Lee; Elise S. Withers; Isaac Kremsky; Richard E. Baker et al.
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Crossref

Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness.

Human molecular genetics
2020-08-01 | Journal article
Source: Self-asserted source
Maria C. Sterrett

A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons

PLOS Genetics
2020-07-09 | Journal article
Contributors: Derrick J. Morton; Hugo J. Bellen; Binta Jalloh; Lily Kim; Isaac Kremsky; Rishi J. Nair; Khuong B. Nguyen; J. Christopher Rounds; Maria C. Sterrett; Brianna Brown et al.
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Crossref

Post-Transcriptional Regulation of Gene Expression and Human Genetic Disease

Source: Self-asserted source
Maria C. Sterrett

Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster larval development.

Development (Cambridge, England)
2019-09-12 | Journal article
Source: Self-asserted source
Maria C. Sterrett

Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth.

Proceedings of the National Academy of Sciences of the United States of America
2017-01-23 | Journal article
Source: Self-asserted source
Maria C. Sterrett