Personal information

United States

Activities

Employment (3)

Cornell University: Ithaca, New York, US

2022-07-05 to present | Assistant Professor (Baker Institute for Animal Health)
Employment
Source: Self-asserted source
Caddy

University of Cambridge: Cambridge, GB

2019-09-01 to present | Clinical Research Fellow (CITIID, Department of Medicine)
Employment
Source: Self-asserted source
Caddy

MRC-Laboratory of Molecular Biology: Cambridge, GB

2015-10-01 to 2019-08-31 | Post-doc (PNAC)
Employment
Source: Self-asserted source
Caddy

Education and qualifications (3)

Imperial College London: London, GB

2011-10-01 to 2015-04-08 | PhD (Medicine)
Education
Source: Self-asserted source
Caddy

University of Cambridge: Cambridge, Cambridgeshire, GB

2006-06-01 to 2009-06-27 | VetMB (Veterinary Medicine)
Education
Source: Self-asserted source
Caddy

University of Cambridge: Cambridge, Cambridgeshire, GB

2003-10-08 to 2006-06-01 | BA in Medical and Veterinary Tripos (Selwyn College)
Education
Source: Self-asserted source
Caddy

Funding (1)

The maternal antibody paradox: Characterising mechanisms and devising solutions for rotavirus vaccination

2019-01-01 to 2022-07-01 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

211138/Z/18/Z

Source: Self-asserted source
Caddy via DimensionsWizard

Works (46)

Protective mechanisms of nonneutralizing antiviral antibodies

PLOS Pathogens
2023-10-05 | Journal article
Contributors: Tawny L. Chandler; Matthew J. Evans; Agnes Yang; Claire E. Otero; Sallie R. Permar; Sarah L. Caddy
Source: check_circle
Crossref

Virus neutralisation by intracellular antibodies.

Seminars in cell & developmental biology
2021-11 | Journal article
Contributors: Bottermann M; Caddy SL
Source: Self-asserted source
Caddy via Europe PubMed Central

A functional assay for serum detection of antibodies against SARS‐CoV‐2 nucleoprotein

The EMBO Journal
2021-09 | Journal article
Contributors: Anna Albecka; Dean Clift; Marina Vaysburd; Tyler Rhinesmith; Sarah L Caddy; David M Favara; Helen E Baxendale; Leo C James
Source: check_circle
Crossref

Prospective trial of different antimicrobial treatment durations for presumptive canine urinary tract infections.

BMC veterinary research
2021-09 | Journal article
Contributors: Allerton F; Pouwels KB; Bazelle J; Caddy S; Cauvin A; De Risio L; Swann J; Warland J; Kent A
Source: Self-asserted source
Caddy via Europe PubMed Central

Rotavirus research: 2014-2020.

Virus research
2021-07 | Journal article
Contributors: Caddy S; Papa G; Borodavka A; Desselberger U
Source: Self-asserted source
Caddy via Europe PubMed Central

Small animal disease surveillance 2020/21: SARS-CoV-2, syndromic surveillance and an outbreak of acute vomiting in UK dogs.

The Veterinary record
2021-04 | Journal article
Contributors: Collins M; Singleton DA; Noble PJM; Pinchbeck GL; Smith S; Brant B; Smyth S; Radford AD; Appleton C; Jewell C et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Genomic epidemiology of COVID-19 in care homes in the east of England.

eLife
2021-03 | Journal article
Contributors: Hamilton WL; Tonkin-Hill G; Smith ER; Aggarwal D; Houldcroft CJ; Warne B; Meredith LW; Hosmillo M; Jahun AS; Curran MD et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

The EMBO Journal
2021-03 | Journal article
Contributors: Sarah L Caddy; Marina Vaysburd; Guido Papa; Mark Wing; Kevin O’Connell; Diana Stoycheva; Stian Foss; Jan Terje Andersen; Annette Oxenius; Leo C James
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Patterns of within-host genetic diversity in SARS-CoV-2

2020-12 | Preprint
Contributors: Tonkin-Hill G; Martincorena I; Amato R; Lawson ARJ; Gerstung M; Johnston I; Jackson DK; Park NR; Lensing SV; Quail MA et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.

Cell
2020-11 | Journal article
Contributors: Volz E; Hill V; McCrone JT; Price A; Jorgensen D; O'Toole Á; Southgate J; Johnson R; Jackson B; Nascimento FF et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

A2B-COVID: A method for evaluating potential SARS-CoV-2 transmission events

2020-10 | Preprint
Contributors: Illingworth CJR; Hamilton WL; Jackson C; Popay A; Meredith L; Houldcroft CJ; Hosmillo M; Jahun A; Routledge M; Warne B et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Genomic epidemiology of COVID-19 in care homes in the East of England

2020-09 | Preprint
Contributors: Hamilton WL; Tonkin-Hill G; Smith E; Aggarwal D; Houldcroft CJ; Warne B; Brown CS; Meredith LW; Hosmillo M; Jahun AS et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Russian SARS-CoV-2 vaccine.

BMJ (Clinical research ed.)
2020-08 | Journal article
Contributors: Caddy S
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Intracellular neutralisation of rotavirus by VP6-specific IgG

PLOS Pathogens
2020-08-04 | Journal article
Contributors: Sarah L. Caddy; Gregory Tiao; Marina Vaysburd; Mark Wing; Stian Foss; Jan Terje Andersen; Kevin O‘Connell; Keith Mayes; Katie Higginson; Miren Iturriza-Gómara et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study.

The Lancet. Infectious diseases
2020-07 | Journal article
Contributors: Meredith LW; Hamilton WL; Warne B; Houldcroft CJ; Hosmillo M; Jahun AS; Curran MD; Parmar S; Caller LG; Caddy SL et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.

eLife
2020-06 | Journal article
Contributors: Jones NK; Rivett L; Sparkes D; Forrest S; Sridhar S; Young J; Pereira-Dias J; Cormie C; Gill H; Reynolds N et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Developing a vaccine for covid-19.

BMJ (Clinical research ed.)
2020-05 | Journal article
Contributors: Caddy S
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Rapid implementation of real-time SARS-CoV-2 sequencing to investigate healthcare-associated COVID-19 infections

2020-05 | Preprint
Contributors: Meredith LW; Hamilton WL; Warne B; Houldcroft CJ; Hosmillo M; Jahun AS; Curran MD; Parmar S; Caller LG; Caddy SL et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission.

eLife
2020-05 | Journal article
Contributors: Rivett L; Sridhar S; Sparkes D; Routledge M; Jones NK; Forrest S; Young J; Pereira-Dias J; Hamilton WL; Ferris M et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Call for coordinated antimicrobial approach at veterinary diagnostic laboratories.

The Veterinary record
2019-06 | Journal article
Contributors: Allerton F; Fishwick J; Paterson S; Weller R; Battersby I; Doyle R; Gould D; Caddy S; Dunning M; Featherstone HJ et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues.

Molecular therapy. Methods & clinical development
2019-06 | Journal article
Contributors: Chandler LC; Barnard AR; Caddy SL; Patrício MI; McClements ME; Fu H; Rada C; MacLaren RE; Xue K
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Complement C4 Prevents Viral Infection through Capsid Inactivation.

Cell host & microbe
2019-03 | Journal article
Contributors: Bottermann M; Foss S; Caddy SL; Clift D; van Tienen LM; Vaysburd M; Cruickshank J; O'Connell K; Clark J; Mayes K et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Enhancement of AAV Transduction Using Anti-Malarial Drugs, Hydroxychloroquine and Chloroquine

Molecular Therapy
2018 | Journal article
Contributors: Xue, Kanmin; Chandler, Laurel C.; Barnard, Alun R.; Caddy, Sarah L.; Patricio, Maria I.; Fu, Howell; Rada, Cristina; James, Leo C.; MacLaren, Robert E.
Source: check_circle
Web of Science Researcher Profile Sync

Ten-minute chat

Veterinary Record
2018 | Journal article
Contributors: Caddy, Sarah
Source: check_circle
Web of Science Researcher Profile Sync

Evaluating the effect of metronidazole plus amoxicillin‐clavulanate versus amoxicillin‐clavulanate alone in canine haemorrhagic diarrhoea: a randomised controlled trial in primary care practice

Journal of Small Animal Practice
2018-07 | Journal article
Contributors: V. Ortiz; L. Klein; S. Channell; B. Simpson; B. Wright; C. Edwards; R. Gilbert; R. Day; S. L. Caddy
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Characterization of innate immune viral sensors in patients following allogeneic hematopoietic stem cell transplantation

Innate Immunity
2018-02 | Journal article
Contributors: Sarah L Caddy; Meng Wang; Pramila Krishnamurthy; Benjamin Uttenthal; Anita Chandra; Charles Crawley; Leo C James
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Investigation of intracellular innate immune responses to AAV gene therapy in the retina

Investigative Ophthalmology & Visual Science
2017 | Journal article
Contributors: Chandler, Laurel Clare; Fu, Howell; Caddy, Sarah; Barnard, Alun R.; Patricio, Maria Ins; James, Leo; Rada, Cristina; MacLaren, Robert E.; Xue, Kanmin
Source: check_circle
Web of Science Researcher Profile Sync

New viruses associated with canine gastroenteritis.

Veterinary journal (London, England : 1997)
2017-12 | Journal article
Contributors: Caddy SL
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Wellcome open research
2017-10 | Journal article
Contributors: Cutler AJ; Oliveira J; Ferreira RC; Challis B; Walker NM; Caddy S; Lu J; Stevens HE; Smyth DJ; Pekalski ML et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Hepatitis E in southern Vietnam: Seroepidemiology in humans and molecular epidemiology in pigs.

Zoonoses and public health
2017-06 | Journal article
Contributors: Berto A; Pham HA; Thao TTN; Vy NHT; Caddy SL; Hiraide R; Tue NT; Goodfellow I; Carrique-Mas JJ; Thwaites GE et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Virus genomes reveal factors that spread and sustained the Ebola epidemic.

Nature
2017-04 | Journal article
Contributors: Dudas G; Carvalho LM; Bedford T; Tatem AJ; Baele G; Faria NR; Park DJ; Ladner JT; Arias A; Asogun D et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors.

Molecular & cellular proteomics : MCP
2017-01 | Journal article
Contributors: Emmott E; Sorgeloos F; Caddy SL; Vashist S; Sosnovtsev S; Lloyd R; Heesom K; Locker N; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Activation of nuclear and cytosolic innate immunity by AAV gene therapy in the retina

Human Gene Therapy
2016 | Journal article
Contributors: Xue, Kanmin; Fu, Howell; Caddy, Sarah L.; Barnard, Alun R.; Patricio, Maria I.; James, Leo C.; Rada, Cristina; MacLaren, Robert E.
Source: check_circle
Web of Science Researcher Profile Sync

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

PLoS medicine
2016-10 | Journal article
Contributors: Todd JA; Evangelou M; Cutler AJ; Pekalski ML; Walker NM; Stevens HE; Porter L; Smyth DJ; Rainbow DB; Ferreira RC et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

First Directly Sequenced Genome of Hepatitis E Virus from the Serum of a Patient from the United Kingdom.

Genome announcements
2016-09 | Journal article
Contributors: Caddy SL; Goodfellow I; Jalal H
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Virus genomes reveal the factors that spread and sustained the West African Ebola epidemic

2016-09 | Preprint
Contributors: Dudas G; Carvalho LM; Bedford T; Tatem AJ; Baele G; Faria N; Park DJ; Ladner J; Arias A; Asogun D et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors

2016-06 | Preprint
Contributors: Emmott E; Sorgeloos F; Caddy SL; Vashist S; Sosnovtsev S; Lloyd R; Heesom K; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases.

Virus evolution
2016-01 | Journal article
Contributors: Arias A; Watson SJ; Asogun D; Tobin EA; Lu J; Phan MVT; Jah U; Wadoum REG; Meredith L; Thorne L et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Detection of Hepatitis E Virus Antibodies in Dogs in the United Kingdom.

PloS one
2015-06 | Journal article
Contributors: McElroy A; Hiraide R; Bexfield N; Jalal H; Brownlie J; Goodfellow I; Caddy SL
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Evidence for human norovirus infection of dogs in the United kingdom.

Journal of clinical microbiology
2015-04 | Journal article
Contributors: Caddy SL; de Rougemont A; Emmott E; El-Attar L; Mitchell JA; Hollinshead M; Belliot G; Brownlie J; Le Pendu J; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Complete genome sequence of canine astrovirus with molecular and epidemiological characterisation of UK strains.

Veterinary microbiology
2015-03 | Journal article
Contributors: Caddy SL; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2015-01 | Journal article
Contributors: Smits SL; Pas SD; Reusken CB; Haagmans BL; Pertile P; Cancedda C; Dierberg K; Wurie I; Kamara A; Kargbo D et al.
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Genogroup IV and VI canine noroviruses interact with histo-blood group antigens.

Journal of virology
2014-07 | Journal article
Contributors: Caddy S; Breiman A; le Pendu J; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Murine norovirus: propagation, quantification, and genetic manipulation.

Current protocols in microbiology
2014-05 | Journal article
Contributors: Hwang S; Alhatlani B; Arias A; Caddy SL; Christodoulou C; Cunha JB; Emmott E; Gonzalez-Hernandez M; Kolawole A; Lu J et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Serological evidence for multiple strains of canine norovirus in the UK dog population.

PloS one
2013-12 | Journal article
Contributors: Caddy S; Emmott E; El-Attar L; Mitchell J; de Rougemont A; Brownlie J; Goodfellow I
Source: Self-asserted source
Caddy via Europe PubMed Central
grade
Preferred source (of 2)‎

Late gestation undernutrition can predispose for visceral adiposity by altering fat distribution patterns and increasing the preference for a high-fat diet in early postnatal life.

The British journal of nutrition
2012-10 | Journal article
Contributors: Nielsen MO; Kongsted AH; Thygesen MP; Strathe AB; Caddy S; Quistorff B; Jørgensen W; Christensen VG; Husted S; Chwalibog A et al.
Source: Self-asserted source
Caddy via Europe PubMed Central

Peer review (42 reviews for 18 publications/grants)

Review activity for BMC medicine (2)
Review activity for Clinical medicine. (1)
Review activity for eLife (1)
Review activity for Journal of clinical virology. (1)
Review activity for Journal of epidemiology and global health. (1)
Review activity for Journal of general virology. (5)
Review activity for Journal of veterinary internal medicine. (3)
Review activity for MBio. (2)
Review activity for Nature communications (3)
Review activity for Pathogens. (2)
Review activity for PLOS pathogens : (1)
Review activity for Science. (1)
Review activity for Transboundary and emerging diseases. (3)
Review activity for Vaccines. (1)
Review activity for Virology journal (4)
Review activity for Virus research. (4)
Review activity for Viruses. (6)
Review activity for Zoonoses and public health. (1)