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Scopus Author ID: 56891394400
Scopus Author ID: 56891394400

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Employment (4)

University of St Andrews: St Andrews, GB

Employment
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University of St Andrews CRIS

University of Cambridge: Cambridge, GB

2019-03-01 to present | Research associate (Chemistry)
Employment
Source: Self-asserted source
John S H Danial

University of Tübingen: Tübingen, DE

2017-02-01 to 2019-02-28 | Research fellow (Interfaculty Institute of Biochemistry)
Employment
Source: Self-asserted source
John S H Danial

Max Planck Institute for Intelligent Systems: Stuttgart, DE

2016-02-01 to 2017-01-31 | Research fellow
Employment
Source: Self-asserted source
John S H Danial

Education and qualifications (1)

University of Oxford: Oxford, Oxfordshire, GB

2012-10-01 to 2015-09-30 | Predoctoral fellow (Chemistry)
Qualification
Source: Self-asserted source
John S H Danial

Works (22)

Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge

Brain Communications
2024-12-24 | Journal article
DOI: 10.1093/braincomms/fcae454
Contributors: Emre Fertan; Christy Hung; John S H Danial; Jeff Y L Lam; Pranav Preman; Giulia Albertini; Elizabeth A English; Dorothea Böken; Frederick J Livesey; Bart De Strooper et al.
Source: check_circle
Crossref

Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly

EMBO Journal
2024-10-01 | Journal article | Author
DOI: 10.1038/s44318-024-00190-6
SOURCE-WORK-ID:

e48cee92-da6b-4262-9491-eb8050e1bfc6

EID:

2-s2.0-85204227991
Contributors: Eleonora Margheritis; Shirin Kappelhoff; John S H Danial; Nadine Gehle; Wladislaw Kohl; Rainer Kurre; Ayelén González Montoro; Katia Cosentino
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University of St Andrews CRIS

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease

PLoS Biology
2024-07-23 | Journal article | Author
DOI: 10.1371/journal.pbio.3002727
SOURCE-WORK-ID:

6dcfa40b-87e4-45ca-baa3-781276fafd2d

EID:

2-s2.0-85199359683
Contributors: Rikesh M. Rajani; Robert Ellingford; Mariam Hellmuth; Samuel S. Harris; Orjona S. Taso; David Graykowski; Francesca Kar Wey Lam; Charles Arber; Emre Fertan; John S H Danial et al.
Source: check_circle
University of St Andrews CRIS

Co-aggregation with apolipoprotein E modulates the function of amyloid-β in Alzheimer's disease

Nature Communications
2024-06-01 | Journal article | Author
DOI: 10.1038/s41467-024-49028-z
SOURCE-WORK-ID:

da7f00f6-dd26-49d6-abc4-55566d3b5550

EID:

2-s2.0-85194995852
Contributors: Zengjie Xia; Emily E Prescott; Agnieszka Urbanek; Hollie E Wareing; Marianne C King; Anna Olerinyova; Helen Dakin; Tom Leah; Katy A Barnes; Martyna M Matuszyk et al.
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University of St Andrews CRIS

Author Correction: Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging

Nature Protocols
2023-12 | Journal article
DOI: 10.1038/s41596-023-00909-5
Contributors: John S. H. Danial; Jeff Y. L. Lam; Yunzhao Wu; Matthew Woolley; Eleni Dimou; Matthew R. Cheetham; Derya Emin; David Klenerman
Source: check_circle
Crossref

Cerebral organoids with chromosome 21 trisomy secrete Alzheimer's disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy.

Molecular psychiatry
2023-12-15 | Journal article
DOI: 10.1038/s41380-023-02333-3
PMID: 38102482
Contributors: Fertan E; Böken D; Aoife Murray; Danial JSH; Lam JYL; Wu Y; Goh PA; Ivan Alić; Cheetham MR; Lobanova E et al.
Source: Self-asserted source
John S H Danial

A computational suite for the structural and functional characterization of amyloid aggregates

Cell Reports Methods
2023-06 | Journal article
DOI: 10.1016/j.crmeth.2023.100499
Part of ISSN: 2667-2375
Contributors: Zengjie Xia; Yunzhao Wu; Jeff Yui Long Lam; Ziwei Zhang; Melanie Burke; Emre Fertan; Rohan T. Ranasinghe; Eric Hidari; John S.H. Danial; David Klenerman
Source: Self-asserted source
John S H Danial

Real-Time Growth Kinetics Analysis of Macromolecular Assemblies in Cells with Single Molecule Resolution

The Journal of Physical Chemistry A
2023-04-20 | Journal article
DOI: 10.1021/acs.jpca.3c00368
Part of ISSN: 1089-5639
Part of ISSN: 1520-5215
Contributors: John S. H. Danial; Andreas Jenner; Ana J. Garcia-Saez; Katia Cosentino
Source: Self-asserted source
John S H Danial

Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging

Nature Protocols
2022-11 | Journal article
DOI: 10.1038/s41596-022-00730-6
Contributors: John S. H. Danial; Jeff Y. L. Lam; Yunzhao Wu; Matthew Woolley; Eleni Dimou; Matthew R. Cheetham; Derya Emin; David Klenerman
Source: check_circle
Crossref

An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy

Biophysical Reports
2022-03 | Journal article
DOI: 10.1016/j.bpr.2022.100044
Part of ISSN: 2667-0747
Contributors: Jeff Y.L. Lam; Yunzhao Wu; Eleni Dimou; Ziwei Zhang; Matthew R. Cheetham; Markus Körbel; Zengjie Xia; David Klenerman; John S.H. Danial
Source: Self-asserted source
John S H Danial

The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation.

Molecular cell
2022-02-03 | Journal article
DOI: 10.1016/j.molcel.2022.01.008
PMID: 35120587
PMC: PMC8901441
Contributors: Katia Cosentino; Hertlein V; Jenner A; Dellmann T; Gojkovic M; Peña-Blanco A; Dadsena S; Noel Wajngarten; Danial JSH; Thevathasan JV et al.
Source: Self-asserted source
John S H Danial

Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis

The Journal of Physical Chemistry Letters
2022-01-27 | Journal article
DOI: 10.1021/acs.jpclett.1c03835
Part of ISSN: 1948-7185
Part of ISSN: 1948-7185
Contributors: John S. H. Danial; Yuri Quintana; Uris Ros; Raed Shalaby; Eleonora G. Margheritis; Sabrina Chumpen Ramirez; Christian Ungermann; Ana J. García-Sáez; Katia Cosentino
Source: Self-asserted source
John S H Danial

DeepSinse: deep learning-based detection of single molecules

Bioinformatics
2021-11-05 | Journal article
DOI: 10.1093/bioinformatics/btab352
Contributors: John S H Danial; Raed Shalaby; Katia Cosentino; Marwa M Mahmoud; Fady Medhat; David Klenerman; Ana J Garcia Saez; Olga Vitek
Source: check_circle
Crossref

Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease

Brain Communications
2021-07-01 | Journal article
DOI: 10.1093/braincomms/fcab147
Contributors: Dimitrios I Sideris; John S H Danial; Derya Emin; Francesco S Ruggeri; Zengjie Xia; Yu P Zhang; Evgeniia Lobanova; Helen Dakin; Suman De; Alyssa Miller et al.
Source: check_circle
Crossref

Quantitative analysis of super-resolved structures using ASAP

Nature Methods
2019-07-01 | Journal article
DOI: 10.1038/s41592-019-0472-1
Part of ISSN: 1548-7091
Part of ISSN: 1548-7105
Source: Self-asserted source
John S H Danial
grade
Preferred source (of 2)‎

Improving certainty in single molecule imaging

Current Opinion in Structural Biology
2017 | Journal article
DOI: 10.1016/j.sbi.2017.04.007
EID:

2-s2.0-85018326757
Contributors: Danial, J.S.; García-Sáez, A.J.
Source: Self-asserted source
John S H Danial via Scopus - Elsevier

On demand modulation of lipid composition in an individual bilayer

Soft Matter
2017 | Journal article
DOI: 10.1039/c6sm01774f
EID:

2-s2.0-85014356028
Contributors: Danial, J.S.H.; Cronin, B.; Mallik, C.; Walllace, M.I.
Source: Self-asserted source
John S H Danial via Scopus - Elsevier

Advanced fluorescence microscopy techniques for the life sciences

2016-10-05 | Journal article
DOI: 10.21542/gcsp.2016.16
Part of ISSN: 2305-7823
Source: Self-asserted source
John S H Danial

Dynamic label-free imaging of lipid nanodomains

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
DOI: 10.1073/pnas.1508483112
EID:

2-s2.0-84943339240
Contributors: De Wit, G.; Danial, J.S.H.; Kukura, P.; Wallace, M.I.
Source: Self-asserted source
John S H Danial via Scopus - Elsevier

Probing Channel, Pump, and Transporter Function Using Single-Molecule Fluorescence

Pumps, Channels and Transporters: Methods of Functional Analysis
2015 | Book chapter
Part of DOI: 10.1002/9781119085126.ch11
EID:

2-s2.0-84977439714
Contributors: Weatherill, E.E.; Danial, J.S.H.; Wallace, M.I.
Source: Self-asserted source
John S H Danial via Scopus - Elsevier

Pumps, Channels, and Transporters
Source: Self-asserted source
John S H Danial

Imaging the lipid-phase-dependent pore formation of equinatoxin II in droplet interface bilayers

Biophysical Journal
2014 | Journal article
DOI: 10.1016/j.bpj.2013.11.4507
EID:

2-s2.0-84898862702
Contributors: Rojko, N.; Cronin, B.; Danial, J.S.H.; Baker, M.A.B.; Anderluh, G.; Wallace, M.I.
Source: Self-asserted source
John S H Danial via Scopus - Elsevier
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