David Sinclair

ORCID iD
https://orcid.org/0000-0002-9936-436X

Biography

David Sinclair, Ph.D. is a Professor at Harvard Medical School in the Department of Genetics and at the University of New South Wales, an Honorary Professor at Sydney University and co-Director of the Harvard/Paul F. Glenn Laboratories for the Biological Mechanisms of Aging. After a Ph.D. in Australia, he worked with Lenny Guarente at M.I.T. where he discovered a cause of aging in yeast controlled by genes called the sirtuins. In 1999, he moved to Harvard Medical School where his lab works primarily on understanding the role of sirtuins in diseases and aging in mammals, with interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer. He has also contributed to the understanding of how sirtuins are modulated by endogenous molecules and pharmacological agents such as resveratrol. He has co-founded biotechnology companies and is co-founder and co-chief editor of the journal Aging. Dr. Sinclair has received awards including The Australian Commonwealth Prize, a Helen Hay Whitney Postdoctoral Award, a Leukemia Society Fellowship, a Ludwig Scholarship, a Harvard-Armenise Fellowship, an American Association for Aging Research Fellowship, The Nathan Shock Award from NIH, Scholarships from The Ellison Medical Foundation, The Merck Prize, the Genzyme Outstanding Achievement in Biomedical Science Award, a "Bio-Innovator award", the David Murdock-Dole Lectureship, the Fisher Honorary Lectureship at UCLA, a MERIT Award from the National Institute on Aging, the Denham Harman Award, and the ASRM Medal from the Australian Society for Medical Research, and listed by TIME magazine as one of the 100 most influential people in the world in 2014.

Record last modified Feb 5, 2018 11:27:44 PM