Personal information

Emails & domains

Verified email domains

Activities

Collapse all

Works (49)

Targeting the brain 5-HT7 receptor to prevent hypomyelination in a rodent model of perinatal white matter injuries

Journal of Neural Transmission
2022-11-06 | Journal article
DOI: 10.1007/s00702-022-02556-8
Part of ISSN: 0300-9564
Part of ISSN: 1435-1463
Contributors: Sophie Lebon; Cindy Bokobza; Alice Jacquens; David Guenoun; Blandine Bianco; Anne Galland; Maxime Pispisa; Alexandra Cruz; Manuela Zinni; Valérie Faivre et al.
Source: Self-asserted source
Sophie Lebon
grade
Preferred source (of 2)‎

Estrogen Receptor α Inactivation in 2 Sisters: Different Phenotypic Severities for the Same Pathogenic Variant

The Journal of Clinical Endocrinology & Metabolism
2022-05-17 | Journal article | Author
DOI: 10.1210/clinem/dgac065
Part of ISSN: 0021-972X
Part of ISSN: 1945-7197
Contributors: clémence Delcour; Nahla Khawaja; Sergio Gonzalez-Duque; Sophie Lebon; Abir Talbi; Leila Drira; Didier Chevenne; Kamel Ajlouni; Nicolas de Roux
Source: Self-asserted source
Sophie Lebon
grade
Preferred source (of 2)‎

<scp>miR</scp> ‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination

Annals of Neurology
2022-01 | Journal article
DOI: 10.1002/ana.26263
Part of ISSN: 0364-5134
Part of ISSN: 1531-8249
Contributors: Sophie Lebon; Cindy Bokobza; Pooja Joshi; Anne‐Laure Schang; Zsolt Csaba; Valérie Faivre; Amélie Montané; Anne Galland; Anouk Benmamar‐Badel; Emmanuelle Bosher et al.
Source: Self-asserted source
Sophie Lebon
grade
Preferred source (of 2)‎

Liver and brain differential expression of one-carbon metabolism genes during ontogenesis

Scientific Reports
2021-10-26 | Journal article
DOI: 10.1038/s41598-021-00311-9
Part of ISSN: 2045-2322
Contributors: Sophie Lebon; Apolline Imbard; Leslie Schwendimann; Sophie Lebon; Pierre Gressens; Henk J. Blom; Jean-François Benoist
Source: Self-asserted source
Sophie Lebon
grade
Preferred source (of 2)‎

Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly

Cell Reports
2020-04 | Journal article
DOI: 10.1016/j.celrep.2020.03.070
Part of ISSN: 2211-1247
Source: Self-asserted source
Sophie Lebon

Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

Brain
2019-12-01 | Journal article
DOI: 10.1093/brain/awz319
Part of ISSN: 0006-8950
Part of ISSN: 1460-2156
Source: Self-asserted source
Sophie Lebon

Involvement of the synapse‐specific zinc transporter ZnT3 in cadmium‐induced hippocampal neurotoxicity

Journal of Cellular Physiology
2019-09 | Journal article
DOI: 10.1002/jcp.28245
Part of ISSN: 0021-9541
Part of ISSN: 1097-4652
Source: Self-asserted source
Sophie Lebon

Correction to: ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly

Cell Death & Disease
2018-12 | Journal article
DOI: 10.1038/s41419-018-1159-8
Part of ISSN: 2041-4889
Source: Self-asserted source
Sophie Lebon

Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury

Brain, Behavior, and Immunity
2018-11 | Journal article
DOI: 10.1016/j.bbi.2018.09.017
Part of ISSN: 0889-1591
Source: Self-asserted source
Sophie Lebon

Erratum: ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

Cell Death & Disease
2018-01 | Journal article
DOI: 10.1038/cddis.2016.446
Part of ISSN: 2041-4889
Source: Self-asserted source
Sophie Lebon

Role of microglia in a mouse model of paediatric traumatic brain injury

Brain, Behavior, and Immunity
2017-07 | Journal article
DOI: 10.1016/j.bbi.2016.11.001
Part of ISSN: 0889-1591
Source: Self-asserted source
Sophie Lebon

Contribution of mast cells to injury mechanisms in a mouse model of pediatric traumatic brain injury

Journal of Neuroscience Research
2016-12 | Journal article
DOI: 10.1002/jnr.23911
Part of ISSN: 0360-4012
Source: Self-asserted source
Sophie Lebon

Pro-epileptogenic effects of viral-like inflammation in both mature and immature brains

Journal of Neuroinflammation
2016-12 | Journal article
DOI: 10.1186/s12974-016-0773-6
Part of ISSN: 1742-2094
Source: Self-asserted source
Sophie Lebon

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

Cell Death & Disease
2016-10 | Journal article
DOI: 10.1038/cddis.2016.266
Part of ISSN: 2041-4889
Source: Self-asserted source
Sophie Lebon

ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects

The American Journal of Human Genetics
2016-08 | Journal article
DOI: 10.1016/j.ajhg.2016.06.011
Part of ISSN: 0002-9297
Source: Self-asserted source
Sophie Lebon

Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter

Journal of Cerebral Blood Flow & Metabolism
2016-08 | Journal article
DOI: 10.1177/0271678x15608862
Part of ISSN: 0271-678X
Part of ISSN: 1559-7016
Source: Self-asserted source
Sophie Lebon
grade
Preferred source (of 2)‎

The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia

Developmental Neuroscience
2015 | Journal article
DOI: 10.1159/000370031
Part of ISSN: 0378-5866
Part of ISSN: 1421-9859
Source: Self-asserted source
Sophie Lebon

Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures

Journal of Neuroscience
2015-08-26 | Journal article
DOI: 10.1523/jneurosci.0476-15.2015
Part of ISSN: 0270-6474
Part of ISSN: 1529-2401
Source: Self-asserted source
Sophie Lebon

High homocysteine induces betaine depletion

Bioscience Reports
2015-08-01 | Journal article
DOI: 10.1042/bsr20150094
Part of ISSN: 0144-8463
Part of ISSN: 1573-4935
Source: Self-asserted source
Sophie Lebon

Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome

BMC Medical Genetics
2013-12 | Journal article
DOI: 10.1186/1471-2350-14-111
Part of ISSN: 1471-2350
Source: Self-asserted source
Sophie Lebon

Stiripentol exhibits higher anticonvulsant properties in the immature than in the mature rat brain

Epilepsia
2013-12 | Journal article
DOI: 10.1111/epi.12401
Part of ISSN: 0013-9580
Source: Self-asserted source
Sophie Lebon

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

Brain, Behavior, and Immunity
2013-08 | Journal article
DOI: 10.1016/j.bbi.2013.02.005
Part of ISSN: 0889-1591
Source: Self-asserted source
Sophie Lebon

Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies

Human Molecular Genetics
2013-07-15 | Journal article
DOI: 10.1093/hmg/ddt144
Part of ISSN: 1460-2083
Part of ISSN: 0964-6906
Source: Self-asserted source
Sophie Lebon

Neuroprotective Effects of Dexmedetomidine against Glutamate Agonist-induced Neuronal Cell Death Are Related to Increased Astrocyte Brain-derived Neurotrophic Factor Expression

Anesthesiology
2013-05-01 | Journal article
DOI: 10.1097/aln.0b013e318286cf36
Part of ISSN: 0003-3022
Source: Self-asserted source
Sophie Lebon

A NovelRAB33BMutation in Smith-McCort Dysplasia

Human Mutation
2013-02 | Journal article
DOI: 10.1002/humu.22235
Part of ISSN: 1059-7794
Source: Self-asserted source
Sophie Lebon

How can cobalamin injections be spaced in long-term therapy for inborn errors of vitamin B12 absorption?

Molecular Genetics and Metabolism
2012-09 | Journal article
DOI: 10.1016/j.ymgme.2012.07.007
Part of ISSN: 1096-7192
Source: Self-asserted source
Sophie Lebon

A new lysosomal storage disorder resembling Morquio syndrome in sibs

European Journal of Medical Genetics
2012-03 | Journal article
DOI: 10.1016/j.ejmg.2012.01.001
Part of ISSN: 1769-7212
Source: Self-asserted source
Sophie Lebon

Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury

Annals of Neurology
2011-11 | Journal article
DOI: 10.1002/ana.22431
Part of ISSN: 0364-5134
Source: Self-asserted source
Sophie Lebon

VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling

Journal of Clinical Investigation
2011-08-01 | Journal article
DOI: 10.1172/jci43824
Part of ISSN: 0021-9738
Source: Self-asserted source
Sophie Lebon

Respiratory-chain diseases related to complex III deficiency

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
2009-01 | Journal article
DOI: 10.1016/j.bbamcr.2008.06.004
Part of ISSN: 0167-4889
Source: Self-asserted source
Sophie Lebon

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits

Proceedings of the National Academy of Sciences
2008-10-28 | Journal article
DOI: 10.1073/pnas.0803004105
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Sophie Lebon

A novel mutation of the NDUFS7 gene leads to activation of a cryptic exon and impaired assembly of mitochondrial complex I in a patient with Leigh syndrome

Molecular Genetics and Metabolism
2007-09 | Journal article
DOI: 10.1016/j.ymgme.2007.05.010
Part of ISSN: 1096-7192
Source: Self-asserted source
Sophie Lebon

Fatal manifestation of a de novo ND5 mutation: Insights into the pathogenetic mechanisms of mtDNA ND5 gene defects

Mitochondrion
2007-07 | Journal article
DOI: 10.1016/j.mito.2007.01.003
Part of ISSN: 1567-7249
Source: Self-asserted source
Sophie Lebon

A novel mutation in the human complex I NDUFS7 subunit associated with Leigh syndrome

Molecular Genetics and Metabolism
2007-04 | Journal article
DOI: 10.1016/j.ymgme.2006.12.007
Part of ISSN: 1096-7192
Source: Self-asserted source
Sophie Lebon

A novel recurrent mitochondrial DNA mutation inND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia

American Journal of Medical Genetics Part A
2007-01-01 | Journal article
DOI: 10.1002/ajmg.a.31565
Part of ISSN: 1552-4825
Part of ISSN: 1552-4833
Source: Self-asserted source
Sophie Lebon

Phylogenetic approach in medical genetics. Evidence for deleterious role of ND5 gene defect in Leigh patients

Mitochondrion
2006-10 | Journal article
DOI: 10.1016/j.mito.2006.08.048
Part of ISSN: 1567-7249
Source: Self-asserted source
Sophie Lebon

Prenatal diagnosis of myopathy, encephalopathy, lactic acidosis, and stroke-like syndrome: contribution to understanding mitochondrial DNA segregation during human embryofetal development

Journal of Medical Genetics
2006-03-29 | Journal article
DOI: 10.1136/jmg.2005.034140
Part of ISSN: 1468-6244
Source: Self-asserted source
Sophie Lebon

Single cell quantification of the 8993T>G NARP mitochondrial DNA mutation by fluorescent PCR

Molecular Genetics and Metabolism
2005-03 | Journal article
DOI: 10.1016/j.ymgme.2004.10.008
Part of ISSN: 1096-7192
Source: Self-asserted source
Sophie Lebon

Molecular diagnostics of mitochondrial disorders

Biochimica et Biophysica Acta (BBA) - Bioenergetics
2004-12 | Journal article
DOI: 10.1016/j.bbabio.2004.07.007
Part of ISSN: 0005-2728
Source: Self-asserted source
Sophie Lebon

Mitochondrial Complex I Deficiency in Humans

Current Genomics
2004-02-01 | Journal article
DOI: 10.2174/1389202043489971
Part of ISSN: 1389-2029
Source: Self-asserted source
Sophie Lebon

Mutant NDUFS3 subunit of mitochondrial complex I causes Leigh syndrome

Journal of Medical Genetics
2004-01-01 | Journal article
DOI: 10.1136/jmg.2003.014316
Part of ISSN: 1468-6244
Source: Self-asserted source
Sophie Lebon

Recurrent de novo mitochondrial DNA mutations in respiratory chain deficiency

Journal of Medical Genetics
2003 | Journal article
Source: Self-asserted source
Sophie Lebon

Genotypes and Clinical Phenotypes in Children with Cytochrome-cOxidase Deficiency

Neuropediatrics
2003-12 | Journal article
DOI: 10.1055/s-2003-44670
Part of ISSN: 0174-304X
Part of ISSN: 1439-1899
Source: Self-asserted source
Sophie Lebon

The Spectrum of Systemic Involvement in Adults Presenting with Renal Lesion and Mitochondrial tRNA(Leu) Gene Mutation

Journal of the American Society of Nephrology
2003-08 | Journal article
DOI: 10.1097/01.asn.0000080180.51098.02
Part of ISSN: 1046-6673
Part of ISSN: 1533-3450
Source: Self-asserted source
Sophie Lebon

A deletion in the human QP-C gene causes a complex III deficiency resulting in hypoglycaemia and lactic acidosis

Human Genetics
2003-07 | Journal article
DOI: 10.1007/s00439-003-0946-0
Part of ISSN: 0340-6717
Part of ISSN: 1432-1203
Source: Self-asserted source
Sophie Lebon

Genotyping microsatellite DNA markers at putative disease loci in inbred/multiplex families with respiratory chain complex I deficiency allows rapid identification of a novel nonsense mutation (IVS1nt −1) in the NDUFS4 gene in Leigh syndrome

Human Genetics
2003-05 | Journal article
DOI: 10.1007/s00439-002-0884-2
Part of ISSN: 0340-6717
Part of ISSN: 1432-1203
Source: Self-asserted source
Sophie Lebon

The mitochondrial DNA G13513A MELAS mutation in the NADH dehydrogenase 5 gene is a frequent cause of Leigh-like syndrome with isolated complex I deficiency

Journal of Medical Genetics
2003-03 | Journal article
Source: Self-asserted source
Sophie Lebon

Assay of mitochondrial respiratory chain complex I in human lymphocytes and cultured skin fibroblasts

Biochemical and Biophysical Research Communications
2003-01 | Journal article
DOI: 10.1016/s0006-291x(02)03016-4
Part of ISSN: 0006-291X
Source: Self-asserted source
Sophie Lebon

Cell complementation using Genebridge 4 human:rodent hybrids for physical mapping of novel mitochondrial respiratory chain deficiency genes

Human Molecular Genetics
2002-12-15 | Journal article
DOI: 10.1093/hmg/11.26.3273
Part of ISSN: 1460-2083
Source: Self-asserted source
Sophie Lebon
How many people are using ORCID?