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Employment (1)

The University of Tokyo: Bunkyo-ku, Tokyo, JP

2024-09-01 to present | Project Researcher (Graduate School of Medicine)
Employment
Source: Self-asserted source
Jun-ichi Okada

Education and qualifications (3)

The University of Tokyo: Bunkyo, JP

2001-04-01 to 2004-03-31 | Ph.D. (Frontier Science)
Education
Source: Self-asserted source
Jun-ichi Okada

Nagoya Institute of Technology: Nagoya, JP

1999-04-01 to 2001-03-31 | M.A. (Production System Engineering)
Education
Source: Self-asserted source
Jun-ichi Okada

Nagoya Institute of Technology: Nagoya, JP

1995-04-01 to 1999-03-31 | B.S. (Mechanical Engineering)
Education
Source: Self-asserted source
Jun-ichi Okada

Works (50 of 53)

Items per page:
Page 1 of 2

Transition mechanisms from atrial flutter to atrial fibrillation during anti‐tachycardia pacing therapy

Pacing and Clinical Electrophysiology
2023-12 | Journal article
DOI: 10.1111/pace.14863
Contributors: Jun‐ichi Okada; Takumi Washio; Seiryo Sugiura; Toshiaki Hisada
Source: check_circle
Crossref

Low‐energy defibrillation using a base–apex epicardial electrode

Pacing and Clinical Electrophysiology
2023-11 | Journal article
DOI: 10.1111/pace.14832
Contributors: Jun‐ichi Okada; Takumi Washio; Seiryo Sugiura; Toshiaki Hisada
Source: check_circle
Crossref

UT-Heart: A Finite Element Model Designed for the Multiscale and Multiphysics Integration of our Knowledge on the Human Heart

Methods in Molecular Biology
2022 | Book chapter
DOI: 10.1007/978-1-0716-1831-8_10
Part of ISBN: 9781071618301
Part of ISBN: 9781071618318
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Seiryo Sugiura; Jun-Ichi Okada; Takumi Washio; Toshiaki Hisada
Source: Self-asserted source
Jun-ichi Okada

Using incomplete Cholesky factorization to increase the time step in molecular dynamics simulations

Journal of Computational and Applied Mathematics
2022-12 | Journal article
DOI: 10.1016/j.cam.2022.114519
Contributors: Takumi Washio; Xiaoke Cui; Ryo Kanada; Jun-ichi Okada; Seiryo Sugiura; Yasushi Okuno; Shoji Takada; Toshiaki Hisada
Source: check_circle
Crossref

A thermodynamically consistent monte carlo cross-bridge model with a trapping mechanism reveals the role of stretch activation in heart pumping

Frontiers in Physiology
2022-09-08 | Journal article
DOI: 10.3389/fphys.2022.855303
Part of ISSN: 1664-042X
Contributors: Kazunori Yoneda; Ryo Kanada; Jun-ichi Okada; Masahiro Watanabe; Seiryo Sugiura; Toshiaki Hisada; Takumi Washio
Source: Self-asserted source
Jun-ichi Okada

An application of a patient-specific cardiac simulator for the prediction of outcomes after mitral valve replacement: a pilot study

Journal of Artificial Organs
2021-09 | Journal article
DOI: 10.1007/s10047-021-01248-6
Part of ISSN: 1434-7229
Part of ISSN: 1619-0904
Contributors: Hirotada Masuda; Shigeru Miyagawa; Seiryo Sugiura; Takumi Washio; Jun-ichi Okada; Takayoshi Ueno; Koichi Toda; Toru Kuratani; Toshiaki Hisada; Yoshiki Sawa
Source: Self-asserted source
Jun-ichi Okada

Chloroquine and hydroxychloroquine provoke arrhythmias at concentrations higher than those clinically used to treat COVID‐19. A simulation study

Clinical and Translational Science
2021-01-06 | Journal article
DOI: 10.1111/cts.12976
Part of ISSN: 1752-8054
Part of ISSN: 1752-8062
Source: Self-asserted source
Jun-ichi Okada

Ionic mechanisms of ST segment elevation in electrocardiogram during acute myocardial infarction

The Journal of Physiological Sciences
2020-12 | Journal article
DOI: 10.1186/s12576-020-00760-3
Part of ISSN: 1880-6546
Part of ISSN: 1880-6562
Source: Self-asserted source
Jun-ichi Okada

Using Systolic Local Mechanical Load to Predict Fiber Orientation in Ventricles

Frontiers in Physiology
2020-06-09 | Journal article
DOI: 10.3389/fphys.2020.00467
Part of ISSN: 1664-042X
Source: Self-asserted source
Jun-ichi Okada

Patient-specific heart simulation can identify non-responders to cardiac resynchronization therapy

Heart and Vessels
2020-03-12 | Journal article
DOI: 10.1007/s00380-020-01577-1
Part of ISSN: 0910-8327
Part of ISSN: 1615-2573
Source: Self-asserted source
Jun-ichi Okada

Personalized Perioperative Multi-scale, Multi-physics Heart Simulation of Double Outlet Right Ventricle

Annals of Biomedical Engineering
2020-03-09 | Journal article
DOI: 10.1007/s10439-020-02488-y
Part of ISSN: 0090-6964
Part of ISSN: 1573-9686
Source: Self-asserted source
Jun-ichi Okada

Clinical and pharmacological application of multiscale multiphysics heart simulator, UT-Heart

The Korean Journal of Physiology & Pharmacology
2019 | Journal article
DOI: 10.4196/kjpp.2019.23.5.295
Part of ISSN: 1226-4512
Part of ISSN: 2093-3827
Source: Self-asserted source
Jun-ichi Okada

Longitudinal dissociation and transition in thickness of the His–Purkinje system cause various QRS waveforms of surface ECG under His bundle pacing: a simulation study based on clinical observations

Journal of Cardiovascular Electrophysiology
2019-09-19 | Journal article
DOI: 10.1111/jce.14191
Part of ISSN: 1045-3873
Part of ISSN: 1540-8167
Source: Self-asserted source
Jun-ichi Okada
grade
Preferred source (of 2)‎

Absence of rapid propagation through the Purkinje network as a potential cause of line block in the human heart with left bundle branch block

Frontiers in Physiology
2018 | Journal article
DOI: 10.3389/fphys.2018.00056
EID:

2-s2.0-85041803836
Contributors: Okada, J.-I.; Washio, T.; Nakagawa, M.; Watanabe, M.; Kadooka, Y.; Kariya, T.; Yamashita, H.; Yamada, Y.; Momomura, S.-I.; Nagai, R. et al.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Arrhythmic hazard map for a 3D whole-ventricle model under multiple ion channel block

British Journal of Pharmacology
2018 | Journal article
DOI: 10.1111/bph.14357
EID:

2-s2.0-85050464456
Contributors: Okada, J.-I.; Yoshinaga, T.; Kurokawa, J.; Washio, T.; Furukawa, T.; Sawada, K.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier
grade
Preferred source (of 2)‎

Coupling Langevin dynamics with continuum mechanics: Exposing the role of sarcomere stretch activation mechanisms to cardiac function

Frontiers in Physiology
2018 | Journal article
DOI: 10.3389/fphys.2018.00333
EID:

2-s2.0-85045013838
Contributors: Washio, T.; Sugiura, S.; Kanada, R.; Okada, J.-I.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Deformable regions of interest with multiple points for tissue tracking in echocardiography

Medical Image Analysis
2017 | Journal article
DOI: 10.1016/j.media.2016.08.002
EID:

2-s2.0-84988526181
Contributors: Cui, X.; Washio, T.; Chono, T.; Baba, H.; Okada, J.-I.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Multi-scale, tailor-made heart simulation can predict the effect of cardiac resynchronization therapy

Journal of Molecular and Cellular Cardiology
2017 | Journal article
DOI: 10.1016/j.yjmcc.2017.05.006
EID:

2-s2.0-85019647959
Contributors: Okada, J.-I.; Washio, T.; Nakagawa, M.; Watanabe, M.; Kadooka, Y.; Kariya, T.; Yamashita, H.; Yamada, Y.; Momomura, S.-I.; Nagai, R. et al.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Proton-sensing transistor systems for detecting ion leakage from plasma membranes under chemical stimuli

Acta Biomaterialia
2017 | Journal article
DOI: 10.1016/j.actbio.2016.12.018
EID:

2-s2.0-85008472853
Contributors: Imaizumi, Y.; Goda, T.; Schaffhauser, D.F.; Okada, J.-I.; Matsumoto, A.; Miyahara, Y.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Tailor-made heart simulation predicts the effect of cardiac resynchronization therapy in a canine model of heart failure

Medical Image Analysis
2016 | Journal article
DOI: 10.1016/j.media.2016.02.003
EID:

2-s2.0-84960393763
Contributors: Panthee, N.; Okada, J.-I.; Washio, T.; Mochizuki, Y.; Suzuki, R.; Koyama, H.; Ono, M.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Ventricular fiber optimization utilizing the branching structure

International Journal for Numerical Methods in Biomedical Engineering
2016 | Journal article
DOI: 10.1002/cnm.2753
EID:

2-s2.0-84945969221
Contributors: Washio, T.; Yoneda, K.; Okada, J.-I.; Kariya, T.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

An integrated finite element simulation of cardiomyocyte function based on triphasic theory

Frontiers in Physiology
2015 | Journal article
DOI: 10.3389/fphys.2015.00287
EID:

2-s2.0-84946568803
Contributors: Hatano, A.; Okada, J.-I.; Washio, T.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Distinct Functional Roles of Cardiac Mitochondrial Subpopulations Revealed by a 3D Simulation Model

Biophysical Journal
2015 | Journal article
DOI: 10.1016/j.bpj.2015.04.031
EID:

2-s2.0-84930619724
Contributors: Hatano, A.; Okada, J.-I.; Washio, T.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator

Science Advances
2015 | Journal article
DOI: 10.1126/sciadv.1400142
EID:

2-s2.0-85020593160
Contributors: Okada, J.-I.; Yoshinaga, T.; Kurokawa, J.; Washio, T.; Furukawa, T.; Sawada, K.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

The human ether-a-go-go-related gene (hERG) current inhibition selectively prolongs action potential of midmyocardial cells to augment transmural dispersion

Journal of Physiology and Pharmacology
2015 | Journal article
EID:

2-s2.0-84940777461
Contributors: Yasuda, C.; Yasuda, S.; Yamashita, H.; Okada, J.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

A Study on Large Scale Analysis of Cardiomyocyte Coupling Electrical, Chemical and Mechanical Phenomena Based on Triphasic Theory

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A
2013 | Journal article
DOI: 10.1299/kikaia.79.934
Part of ISSN: 0387-5008
Part of ISSN: 1884-8338
Contributors: Asuka HATANO; Jun-ichi OKADA; Takumi WASHIO; Seiryo SUGIURA; Toshiaki HISADA
Source: Self-asserted source
Jun-ichi Okada
grade
Preferred source (of 2)‎

Effects of an hERG Activator, ICA-105574, on Electrophysiological Properties of Canine Hearts

Journal of Pharmacological Sciences
2013 | Journal article
DOI: 10.1254/jphs.12220fp
Part of ISSN: 1347-8613
Part of ISSN: 1347-8648
Contributors: Mahoko Asayama; Junko Kurokawa; Kiyoshi Shirakawa; Hisashi Okuyama; Toshiki Kagawa; Jun-ichi Okada; Seiryo Sugiura; Toshiaki Hisada; Tetsushi Furukawa
Source: Self-asserted source
Jun-ichi Okada
grade
Preferred source (of 2)‎

Mitochondrial colocalization with Ca<sup>2+</sup>release sites is crucial to cardiac metabolism

Biophysical Journal
2013 | Journal article
DOI: 10.1016/j.bpj.2012.12.004
EID:

2-s2.0-84872787769
Contributors: Hatano, A.; Okada, J.-I.; Washio, T.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Modeling for cardiac excitation propagation based on the Nernst-Planck equation and homogenization

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
2013 | Journal article
DOI: 10.1103/PhysRevE.87.062701
EID:

2-s2.0-84879224933
Contributors: Okada, J.-I.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Multiscale heart simulation with cooperative stochastic cross-bridge dynamics and cellular structures

Multiscale Modeling and Simulation
2013 | Journal article
DOI: 10.1137/120892866
EID:

2-s2.0-84890939632
Contributors: Washio, T.; Okada, J.I.; Takahashi, A.; Yoneda, K.; Kadooka, Y.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Patient Specific Simulation of Body Surface ECG using the Finite Element Method

PACE - Pacing and Clinical Electrophysiology
2013 | Journal article
DOI: 10.1111/pace.12057
EID:

2-s2.0-84874776151
Contributors: Okada, J.-I.; Sasaki, T.; Washio, T.; Yamashita, H.; Kariya, T.; Imai, Y.; Nakagawa, M.; Kadooka, Y.; Nagai, R.; Hisada, T. et al.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Approximation for cooperative interactions of a spatially-detailed cardiac sarcomere model

Cellular and Molecular Bioengineering
2012 | Journal article
DOI: 10.1007/s12195-011-0219-2
EID:

2-s2.0-84857900336
Contributors: Washio, T.; Okada, J.-I.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Critical role of cardiac t-tubule system for the maintenance of contractile function revealed by a 3D integrated model of cardiomyocytes

Journal of Biomechanics
2012 | Journal article
DOI: 10.1016/j.jbiomech.2011.11.022
EID:

2-s2.0-84857655163
Contributors: Hatano, A.; Okada, J.-I.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Multi-scale simulations of cardiac electrophysiology and mechanics using the University of Tokyo heart simulator

Progress in Biophysics and Molecular Biology
2012 | Journal article
DOI: 10.1016/j.pbiomolbio.2012.07.001
EID:

2-s2.0-84868089279
Contributors: Sugiura, S.; Washio, T.; Hatano, A.; Okada, J.; Watanabe, H.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

三相理論に基づく心筋細胞の電気生理・力学統合解析

生体医工学
2012 | Journal article
DOI: 10.11239/jsmbe.50.591
Part of ISSN: 1347443X
Part of ISSN: 18814379
Contributors: 明日可 波田野; 純一 岡田; 巧 鷲尾; 俊明 久田; 清了 杉浦
Source: Self-asserted source
Jun-ichi Okada

心電図の数理

応用数理
2012 | Journal article
DOI: 10.11540/bjsiam.22.4_238
Part of ISSN: 24321982
Contributors: 純一 岡田
Source: Self-asserted source
Jun-ichi Okada

A three-dimensional simulation model of cardiomyocyte integrating excitation-contraction coupling and metabolism

Biophysical Journal
2011 | Journal article
DOI: 10.1016/j.bpj.2011.10.020
EID:

2-s2.0-82955240532
Contributors: Hatano, A.; Okada, J.-I.; Washio, T.; Hisada, T.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Transmural and apicobasal gradients in repolarization contribute to T-wave genesis in human surface ECG

American Journal of Physiology - Heart and Circulatory Physiology
2011 | Journal article
DOI: 10.1152/ajpheart.01241.2010
EID:

2-s2.0-79959867969
Contributors: Okada, J.; Washio, T.; Maehara, A.; Momomura, S.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

心筋細胞のエネルギー代謝におけるミトコンドリアと筋小胞体Ca<sup>2+</sup>放出チャネルの相対位置の重要性

生体医工学
2011 | Journal article
DOI: 10.11239/jsmbe.49.829
Part of ISSN: 1347443X
Part of ISSN: 18814379
Contributors: 明日可 波田野; 純一 岡田; 巧 鷲尾; 俊明 久田; 清了 杉浦
Source: Self-asserted source
Jun-ichi Okada

A multi-scale heart simulation on massively parallel computers

2010 ACM/IEEE International Conference for High Performance Computing, Networking, Storage and Analysis, SC 2010
2010 | Conference paper
DOI: 10.1109/SC.2010.5
EID:

2-s2.0-78650964946
Contributors: Hosoi, A.; Washio, T.; Okada, J.-I.; Kadooka, Y.; Nakajima, K.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

A parallel multilevel technique for solving the bidomain equation on a human heart with purkinje fibers and a torso model

SIAM Review
2010 | Journal article
DOI: 10.1137/100798429
EID:

2-s2.0-79952954616
Contributors: Washio, T.; Okada, J.-I.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

A study on mechano-electrochemical modeling of cardiomyocyte

Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A
2010 | Journal article
DOI: 10.1299/kikaia.76.1806
EID:

2-s2.0-79953204301
Contributors: Hirabayashi, S.; Okada, J.-I.; Washio, T.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Study of efficient homogenization algorithms for nonlinear problems: Approximation of a homogenized tangent stiffness to reduce computational cost

Computational Mechanics
2010 | Journal article
DOI: 10.1007/s00466-009-0432-1
EID:

2-s2.0-77954762282
Contributors: Okada, J.-I.; Washio, T.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Large-scale integrated model is useful for understanding heart mechanisms and developments of medical therapy

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
2009 | Conference paper
DOI: 10.1109/IEMBS.2009.5335029
EID:

2-s2.0-77950966162
Contributors: Washio, T.; Okada, J.-I.; Sugiura, S.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Nonlinear Homogenization Algorithms with Low Computational Cost

Journal of Computational Science and Technology
2009 | Journal article
DOI: 10.1299/jcst.3.101
Part of ISSN: 1881-6894
Contributors: Jun-ichi OKADA; Takumi WASHIO; Toshiaki HISADA
Source: Self-asserted source
Jun-ichi Okada

Study on Compressibility Control of Hyperelastic Material for Homogenization Method Using Mixed Finite Element Analysis

Journal of Computational Science and Technology
2009 | Journal article
DOI: 10.1299/jcst.3.89
Part of ISSN: 1881-6894
Contributors: Jun-ichi OKADA; Toshiaki HISADA
Source: Self-asserted source
Jun-ichi Okada

A parallel multilevel technique for solving the bidomain equation on a human heart with purkinje fibers and a torso model

SIAM Journal on Scientific Computing
2008 | Journal article
DOI: 10.1137/070689711
EID:

2-s2.0-55149122653
Contributors: Washio, T.; Okada, J.-I.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Nonlinear homogenization algorisms with low computational cost

Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A
2008 | Journal article
EID:

2-s2.0-43749095200
Contributors: Okada, J.-I.; Washio, T.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Study on compressibility control of hyperelastic material in homogenization method using mixed finite element analysis

Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A
2007 | Journal article
EID:

2-s2.0-39049122667
Contributors: Okada, J.-I.; Hisada, T.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier

Microtubules modulate the stiffness of cardiomyocytes against shear stress

Circulation Research
2006 | Journal article
DOI: 10.1161/01.RES.0000197785.51819.e8
EID:

2-s2.0-33644833679
Contributors: Nishimura, S.; Nagai, S.; Katoh, M.; Yamashita, H.; Saeki, Y.; Okada, J.-I.; Hisada, T.; Nagai, R.; Sugiura, S.
Source: Self-asserted source
Jun-ichi Okada via Scopus - Elsevier
Items per page:
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