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Works (30)

Whole-genome doubling in tissues and tumors

Trends in Genetics
2023-12 | Journal article
DOI: 10.1016/j.tig.2023.08.004
Contributors: Marc A. Vittoria; Ryan J. Quinton; Neil J. Ganem
Source: check_circle
Crossref

Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis

Nature Communications
2022-07-15 | Journal article
DOI: 10.1038/s41467-022-31899-9
Contributors: Revati Darp; Marc A. Vittoria; Neil J. Ganem; Craig J. Ceol
Source: check_circle
Crossref

Oncogenic BRAF Induces Whole-Genome Doubling Through Suppression of Cytokinesis

2021-05-13 | Preprint
DOI: 10.21203/rs.3.rs-455889/v1
Contributors: Revati Darp; Marc Vittoria; Neil Ganem; Craig Ceol
Source: check_circle
Crossref

Whole-genome doubling confers unique genetic vulnerabilities on tumour cells.

Nature
2021-01-27 | Journal article
DOI: 10.1038/s41586-020-03133-3
PMID: 33505027
Source: Self-asserted source
Neil Ganem

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.

Nature cell biology
2020-02-03 | Journal article
DOI: 10.1038/s41556-020-0463-6
PMID: 32015438
PMC: PMC7076906
Source: Self-asserted source
Neil Ganem

Identification of the kinase STK25 as an upstream activator of LATS signaling.

2019-04-04 | Journal article
DOI: 10.1038/s41467-019-09597-w
PMID: 30948712
Source: check_circle
Boston University

CRISPR-Mediated Approaches to Regulate YAP/TAZ Levels.

2019-01-01 | Journal article
DOI: 10.1007/978-1-4939-8910-2_16
PMID: 30565136
Source: check_circle
Boston University

A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation.

2018-05-23 | Journal article
DOI: 10.1091/mbc.E18-02-0141
PMID: 29791254
Source: check_circle
Boston University

Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel.

2018-05-14 | Journal article
DOI: 10.3791/57383
PMID: 29806834
Source: check_circle
Boston University

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.

2017-11-01 | Journal article
DOI: 10.1126/scitranslmed.aam9078
PMID: 29093183
Source: check_circle
Boston University

STK38L kinase ablation promotes loss of cell viability in a subset of KRAS-dependent pancreatic cancer cell lines.

2017-09-11 | Journal article
DOI: 10.18632/oncotarget.20833
PMID: 29108249
Source: check_circle
Boston University

Nuclear envelope rupture drives genome instability in cancer.

2016-11-01 | Journal article
DOI: 10.1091/mbc.E16-02-0098
PMID: 27799497
Source: check_circle
Boston University

Generation and Purification of Tetraploid Cells.

2016-01-01 | Journal article
DOI: 10.1007/978-1-4939-3542-0_24
PMID: 27193862
Source: check_circle
Boston University

The interplay between centrosomes and the Hippo tumor suppressor pathway.

2016-01-01 | Journal article
DOI: 10.1007/s10577-015-9502-8
PMID: 26582635
Source: check_circle
Boston University

Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes.

2015-03-18 | Journal article
DOI: 10.1002/em.21945
PMID: 25784636
Source: check_circle
Boston University

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.

2015-01-16 | Journal article
DOI: 10.1126/science.1257216
PMID: 25593184
Source: check_circle
Boston University

Tetraploidy and tumor development.

2014-11-30 | Journal article
DOI: 10.18632/oncotarget.2790
PMID: 25526024
Source: check_circle
Boston University

Cytokinesis failure triggers hippo tumor suppressor pathway activation.

2014-08-14 | Journal article
DOI: 10.1016/j.cell.2014.06.029
PMID: 25126788
Source: check_circle
Boston University

Linking abnormal mitosis to the acquisition of DNA damage.

2012-12-10 | Journal article
DOI: 10.1083/jcb.201210040
PMID: 23229895
Source: check_circle
Boston University

DNA breaks and chromosome pulverization from errors in mitosis.

2012-01-18 | Journal article
DOI: 10.1038/nature10802
PMID: 22258507
Source: check_circle
Boston University

Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.

2009-08-24 | Journal article
DOI: 10.1128/MCB.00558-09
PMID: 19704007
Source: check_circle
Boston University

A mechanism linking extra centrosomes to chromosomal instability.

2009-06-07 | Journal article
DOI: 10.1038/nature08136
PMID: 19506557
Source: check_circle
Boston University

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes.

2008-07-28 | Journal article
DOI: 10.1101/gad.1700908
PMID: 18662975
Source: check_circle
Boston University

Limiting the proliferation of polyploid cells.

2007-11-02 | Journal article
PMID: 17981108
Source: check_circle
Boston University

The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

2007-05-30 | Journal article
DOI: 10.1091/mbc.E07-02-0110
PMID: 17538014
Source: check_circle
Boston University

Tetraploidy, aneuploidy and cancer.

2007-02-26 | Journal article
PMID: 17324569
Source: check_circle
Boston University

Functional roles of poleward microtubule flux during mitosis.

2006-03-01 | Journal article
PMID: 16552178
Source: check_circle
Boston University

2-cyano-3,12-dioxooleana-1,9(11)-diene-28-oic acid disrupts microtubule polymerization: a possible mechanism contributing to apoptosis.

2006-01-11 | Journal article
PMID: 16407469
Source: check_circle
Boston University

Efficient mitosis in human cells lacking poleward microtubule flux.

2005-10-25 | Journal article
PMID: 16243029
Source: check_circle
Boston University

The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK.

2004-08-09 | Journal article
DOI: 10.1083/jcb.200404012
PMID: 15302853
Source: check_circle
Boston University
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