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Employment (2)

University of Oxford: Oxford, GB

2024-04 to present | Postdoctoral Research Associate Biochemistry
Employment
Source: Self-asserted source
Mariska de Munnik

GlaxoSmithKline (Spain): Madrid, ES

2018-11 to 2019-09 | Open Lab Fellow (TCOLF)
Employment
Source: Self-asserted source
Mariska de Munnik

Education and qualifications (4)

University of Oxford: Oxford, GB

2019-10 to 2023-10 | DPhil in Chemical Biology (Department of Chemistry)
Education
Source: Self-asserted source
Mariska de Munnik

Vrije Universiteit Amsterdam: Amsterdam, NL

2016-09 to 2018-12 | MSc Drug Discovery and Safety
Education
Source: Self-asserted source
Mariska de Munnik

Vrije Universiteit Amsterdam: Amsterdam, NL

2013-09 to 2016-06 | Bsc Pharmaceutical Sciences
Education
Source: Self-asserted source
Mariska de Munnik

Vrije Universiteit Amsterdam: Amsterdam, NL

2010-10 to 2015-02 | BSc Medicine
Education
Source: Self-asserted source
Mariska de Munnik

Funding (3)

BBSRC fees-only studentship, UKRI, Oxford Interdisciplinary Bioscience DTP, UK, 2019

Grant
Biotechnology and Biological Sciences Research Council (Oxford, GB)
Source: Self-asserted source
Mariska de Munnik

Graduate studentship, Department of Chemistry, University of Oxford, UK, 2019

Grant
University of Oxford (Oxford, GB)
Source: Self-asserted source
Mariska de Munnik

Studies on Nucleophilic Cysteine Enzymes Involved in Bacterial Cell Wall Biosynthesis- iCASE

Grant
Tres Cantos Open Lab Foundation (Guildford, GB)
Source: Self-asserted source
Mariska de Munnik

Works (9)

Targeting Mycobacterial Transpeptidases: Evaluating the Roles of Ldt and PBP Inhibition in SuppressingMycobacterium smegmatis

2025-02-03 | Preprint
DOI: 10.1101/2025.01.28.635326
Contributors: Mariska de Munnik; Karina Calvopiña; Patrick Rabe; Christopher J. Schofield
Source: check_circle
Crossref

Biochemical and crystallographic studies of l,d-transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate

Communications Biology
2024-09-18 | Journal article
DOI: 10.1038/s42003-024-06785-3
Contributors: Mariska de Munnik; Pauline A. Lang; Karina Calvopiña; Patrick Rabe; Jürgen Brem; Christopher J. Schofield
Source: check_circle
Crossref

How Clavulanic Acid Inhibits Serine β‐Lactamases

ChemBioChem
2024-07-25 | Journal article
DOI: 10.1002/cbic.202400280
Part of ISSN: 1439-4227
Part of ISSN: 1439-7633
Contributors: Pauline Lang; Mariska de Munnik; Abraham Oluwole; Timothy Claridge; Carol Robinson; Jurgen Brem; Christopher Schofield
Source: Self-asserted source
Mariska de Munnik

High-throughput screen with the l,d-transpeptidase LdtMt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors

Chemical Science
2023 | Journal article
DOI: 10.1039/D2SC06858C
Contributors: Mariska de Munnik; Pauline A. Lang; Francisco De Dios Anton; Mónica Cacho; Robert H. Bates; Jürgen Brem; Beatriz Rodríguez Miquel; Christopher J. Schofield
Source: check_circle
Crossref

αβ,α′β′-Diepoxyketones are mechanism-based inhibitors of nucleophilic cysteine enzymes

Chemical Communications
2023 | Journal article
DOI: 10.1039/D3CC02932H
Contributors: Mariska de Munnik; Jasper Lithgow; Lennart Brewitz; Kirsten E. Christensen; Robert H. Bates; Beatriz Rodriguez-Miquel; Christopher J. Schofield
Source: check_circle
Crossref

A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2

ChemBioChem
2020-02-03 | Journal article
DOI: 10.1002/cbic.201900379
Contributors: Mariska de Munnik; Christopher T. Lohans; Gareth W. Langley; Corentin Bon; Jürgen Brem; Christopher J. Schofield
Source: check_circle
Crossref

Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2 with cysteine-reactive inhibitors including ebselen

Chemical Communications
2019 | Journal article
DOI: 10.1039/c9cc04145a
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Source: Self-asserted source
Mariska de Munnik
grade
Preferred source (of 2)‎

Non-Hydrolytic β-Lactam Antibiotic Fragmentation by<scp>l,d</scp>-Transpeptidases and Serine β-Lactamase Cysteine Variants

Angewandte Chemie International Edition
2019-02-11 | Journal article
DOI: 10.1002/anie.201809424
Part of ISSN: 1433-7851
Contributors: Christopher Lohans; H. T. Henry Chan; Tika R. Malla; Dr. Kiran Kumar; Jos J. A. G. Kamps; Darius J. B. McArdle; Emma van Groesen; Mariska de Munnik; Catherine Tooke; James Spencer et al.
Source: Self-asserted source
Mariska de Munnik

Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalized Spirooxindole-Fused Thiazolidines

ACS Combinatorial Science
2018-02-12 | Journal article
DOI: 10.1021/acscombsci.7b00179
Part of ISSN: 2156-8952
Part of ISSN: 2156-8944
Contributors: GIULIA RAINOLDI; Fabio Begnini; Mariska de Munnik; Leonardo Lo Presti; Christophe M. L. Vande Velde; Romano Orru; Giordano Lesma; Eelco Ruijter; alessandra silvani
Source: Self-asserted source
Mariska de Munnik
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