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China

Activities

Employment (3)

Institute of Zoology, Chinese Academy of Sciences: Beijing, CN

2021-08-02 to present | Associate Professor (State Key Laboratory of Stem Cell and Reproductive Biology)
Employment
Source: Self-asserted source
Xuan Shao

Institute of Zoology Chinese Academy of Sciences: Beijing, CN

2017-07-01 to 2021-08-01 | Assistant Professor (State Key Laboratory of Stem Cell and Reproductive Biology)
Employment
Source: Self-asserted source
Xuan Shao

Institute of Zoology, Chinese Academy of Sciences: Beijing, CN

2014-07-01 to 2017-07-01 | Postdoc (State Key Laboratory of Stem Cell and Reproductive Biology)
Employment
Source: Self-asserted source
Xuan Shao

Education and qualifications (3)

Institute of Zoology Chinese Academy of Sciences: Beijing, CN

2010-09-01 to 2014-06-30 | Ph.D. (State Key Laboratory of Reproductive Biology)
Education
Source: Self-asserted source
Xuan Shao

Beijing Institute of Pharmacology and Toxicology: Beijing, CN

2007-09-01 to 2010-06-30 | MSc
Education
Source: Self-asserted source
Xuan Shao

Hebei University: Baoding, Hebei Province, CN

2002-09-01 to 2006-06-30 | Bachelor (College of Life Science)
Education
Source: Self-asserted source
Xuan Shao

Works (29)

Fine-tuned programming of placenta trophoblast determines optimal maternal–fetal nutrient allocation

Current Opinion in Genetics & Development
2025-04 | Journal article
Contributors: Xin Yu; Qianqian Li; Xuan Shao; Amanda N Sferruzzi-Perri; Yan-Ling Wang
Source: check_circle
Crossref

TFEB safeguards trophoblast syncytialization in humans and mice

Proceedings of the National Academy of Sciences
2024-07-09 | Journal article
Contributors: Wanshan Zheng; Yue Zhang; Peiqun Xu; Zexin Wang; Xuan Shao; Chunyan Chen; Han Cai; Yinan Wang; Ming-an Sun; Wenbo Deng et al.
Source: check_circle
Crossref

Orchestrated feedback regulation between melatonin and sex hormones involving GPER1‐PKA‐CREB signaling in the placenta

Journal of Pineal Research
2023-12 | Journal article
Contributors: Xuan Shao; Yun Yang; Yanlei Liu; Yongqing Wang; Yangyu Zhao; Xin Yu; Juan Liu; Yu‐Xia Li; Yan‐Ling Wang
Source: check_circle
Crossref

Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at midgestation highlights the defective impacts on foetal health

Cell Proliferation
2022 | Journal article
Contributors: Chen, Jingsi; Du, Lili; Wang, Feiyang; Shao, Xuan; Wang, Xiaoyi; Yu, Wenzhe; Bi, Shilei; Chen, Dexiong; Pan, Xingfei; Zeng, Shanshan et al.
Source: check_circle
Web of Science Researcher Profile Sync

Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia

Journal of Biomedical Science
2022 | Journal article
Contributors: Li, Guanlin; Wang, Yongqing; Cao, Guangming; Ma, Yeling; Li, Yu-Xia; Zhao, Yangyu; Shao, Xuan; Wang, Yan-Ling
Source: check_circle
Web of Science Researcher Profile Sync

Placental Development and Pregnancy-Associated Diseases

Maternal-Fetal Medicine
2022 | Journal article
Contributors: Yu, Xin; Wu, Hongyu; Yang, Yun; Wang, Feiyang; Wang, Yan-Ling; Shao, Xuan
Source: check_circle
Web of Science Researcher Profile Sync

The mystery of the life tree: the placentas(dagger)

Biology of Reproduction
2022 | Journal article
Contributors: Shao, Xuan; Yu, Wenzhe; Yang, Yun; Wang, Feiyang; Yu, Xin; Wu, Hongyu; Ma, Yeling; Cao, Bin; Wang, Yan-Ling
Source: check_circle
Web of Science Researcher Profile Sync

MNSFβ regulates placental development by conjugating IGF2BP2 to enhance trophoblast cell invasiveness

Cell Proliferation
2021-12 | Journal article
Contributors: Qian Yang; Yeling Ma; Yanlei Liu; Xuan Shao; Wentong Jia; Xin Yu; Yu‐xia Li; Long Yang; Wenwen Gu; Haibin Wang et al.
Source: check_circle
Crossref

Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine γ-lyase (CSE) represses trophoblast syncytialization

Cell Chemical Biology
2021-06 | Journal article
Contributors: Juan Liu; Xuan Shao; Wei Qin; Yanling Zhang; Feihong Dang; Qian Yang; Xin Yu; Yu-Xia Li; Xing Chen; Chu Wang et al.
Source: check_circle
Crossref

Single-Cell Immune Landscape of Human Recurrent Miscarriage

Genomics, Proteomics & Bioinformatics
2021-04-01 | Journal article
Contributors: Feiyang Wang; Wentong Jia; Mengjie Fan; Xuan Shao; Zhilang Li; Yongjie Liu; Yeling Ma; Yu-Xia Li; Rong Li; Qiang Tu et al.
Source: check_circle
Crossref

Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply

Proceedings of the National Academy of Sciences
2021-01-19 | Journal article
Contributors: Xuan Shao; Guangming Cao; Dunjin Chen; Juan Liu; Bolan Yu; Ming Liu; Yu-Xia Li; Bin Cao; Yoel Sadovsky; Yan-Ling Wang
Source: check_circle
Crossref

miR-18a Contributes to Preeclampsia by Downregulating Smad2 (Full Length) and Reducing TGF-β Signaling

Molecular Therapy - Nucleic Acids
2020-12 | Journal article
Part of ISSN: 2162-2531
Source: Self-asserted source
Xuan Shao

Uterine decidual niche modulates the progressive dedifferentiation of spiral artery vascular smooth muscle cells during human pregnancy†

Biology of Reproduction
2020-11-06 | Journal article
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Xuan Shao

Uterine Scarring Leads to Adverse Pregnant Consequences by Impairing the Endometrium Response to Steroids

Endocrinology
2020-11-01 | Journal article
Contributors: Zhilang Li; Xiaotao Bian; Yeling Ma; Qian Yang; Wentong Jia; Juan Liu; Feiyang Wang; Ming Liu; Yu-Xia Li; Xuan Shao et al.
Source: check_circle
Crossref

MicroRNA-210 regulates placental adaptation to maternal hypoxic stress during pregnancy†

Biology of Reproduction
2020-10-19 | Journal article
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Xuan Shao

Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T‐cell differentiation along the maternal‐placental circulation

Cell Proliferation
2020-05 | Journal article
Part of ISSN: 0960-7722
Part of ISSN: 1365-2184
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsia†.

Biology of reproduction
2020-03-01 | Journal article
Source: Self-asserted source
Xuan Shao

ASSOCIATION OF STEROID HORMONE IMBALANCE WITH COAGULATORY FACTOR SERPINF2 EXCESS IN PREECLAMPTIC PLACENTA

Placenta
2018 | Journal article
Contributors: Shao, Xuan; Wang, Yongqing; Liu, Yanlei; Guo, Xuejiang; Li, Dong; Huo, Ran; Jia, Wentong; Cao, Guangming; Li, Yu-Xia; Liu, Ming et al.
Source: check_circle
Web of Science Researcher Profile Sync

INFLAMMATORY FACTOR TNFα INDUCES SERPINF2 UPREGULATION AND EXCESSIVE HYPER-COAGULATION IN PREECLAMPSIA

Placenta
2018 | Journal article
Contributors: Liu, Yanlei; Lu, Huifen; Jia, Wentong; Dang, Feihong; Ma, Liyang; Li, Yu-xia; Shao, Xuan; Wang, Yan-ling
Source: check_circle
Web of Science Researcher Profile Sync

Transactivation of Met signalling by semaphorin4D in human placenta: implications for the pathogenesis of preeclampsia.

Journal of hypertension
2018-11-01 | Journal article
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

Placental defects are involved in most gene mutations that cause embryonic and fetal death

Biology of Reproduction
2018-09-01 | Journal article
Contributors: Xuan Shao; Cheng Tan; Dunjin Chen; Yan-Ling Wang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia

Journal of Hypertension
2018-07 | Journal article
Part of ISSN: 0263-6352
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.

ACS chemical biology
2018-07-30 | Journal article
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

miR-518b Enhances Human Trophoblast Cell Proliferation Through Targeting Rap1b and Activating Ras-MAPK Signal.

Frontiers in Endocrinology
2018-03-15 | Journal article
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

Testosterone Represses Estrogen Signaling by Upregulating miR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia.

Hypertension (Dallas, Tex. : 1979)
2017-02-13 | Journal article
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

REGULATION OF THE PRO-COAGULATION FACTOR SERPINF2 BY PLACENTA-SYNTHESIZED STEROID HORMONES: IMPLICATIONS FOR PREGNANCY ADAPTATION OF THE MATERNAL COAGULATION SYSTEM

Placenta
2016 | Journal article
Contributors: Shao, Xuan; Lu, Huifen; Li, Dong; Huo, Ran; Liu, Ming; Liu, Yanlei; Guo, Xuejiang; Cao, Guangming; Li, Yuxia; Sha, Jiahao et al.
Source: check_circle
Web of Science Researcher Profile Sync

Hypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A.

Scientific reports
2016-01-22 | Journal article
Source: Self-asserted source
Xuan Shao
grade
Preferred source (of 2)‎

IDENTIFICATION OF A NOVEL BIOMARKER RELIABLY PREDICTING THE RISK FOR SEVERE PREECLAMPSIA

Placenta
2014 | Journal article
Contributors: Liu, Ming; Wang, Yongqing; Zhao, Yangyu; Shao, Xuan; Ji, Lei; Li, Yuxia; Redman, Christopher; Qiao, Jie; Wang, Yan-ling
Source: check_circle
Web of Science Researcher Profile Sync

MicroRNA-210 contributes to preeclampsia by downregulating potassium channel modulatory factor 1

Hypertension
2014 | Journal article
EID:

2-s2.0-84914682894

Contributors: Luo, R.; Shao, X.; Xu, P.; Liu, Y.; Wang, Y.; Zhao, Y.; Liu, M.; Ji, L.; Li, Y.-X.; Chang, C. et al.
Source: Self-asserted source
Xuan Shao via Scopus - Elsevier
grade
Preferred source (of 2)‎

Peer review (69 reviews for 12 publications/grants)

Review activity for Advanced science. (5)
Review activity for American journal of physiology. (1)
Review activity for Biology of reproduction. (14)
Review activity for Biology of reproduction. (16)
Review activity for BMC pregnancy and childbirth (2)
Review activity for Communications biology. (1)
Review activity for Journal of integrative medicine. (1)
Review activity for Journal of molecular histology. (1)
Review activity for Journal of molecular histology. (1)
Review activity for Placenta. (24)
Review activity for Reproductive Biology. (1)
Review activity for The journal of maternal-fetal & neonatal medicine (2)