Personal information

Other IDs

Scopus Author ID: 55361602800

Activities

Collapse all

Employment (4)

Universidade Federal de Ciências da Saúde de Porto Alegre: Porto Alegre, BR

2022-12-01 to present | Postdoctoral Research Associate (PPGBio)
Employment
Source: Self-asserted source
Conrado Pedebos

University of Oxford: Oxford, Oxfordshire, GB

2021-08-01 to 2022-08-01 | Research Fellow (Department of Biochemistry)
Employment
Source: Self-asserted source
Conrado Pedebos

University of Southampton: Southampton, Hampshire, GB

2019-04-10 to 2021-07-31 | Research Fellow (School of Chemistry)
Employment
Source: Self-asserted source
Conrado Pedebos

University of Nottingham: Nottingham, Nottinghamshire, GB

2017-10-16 to 2018-12-31 | Research Associate (School of Pharmacy, Centre for Biomolecular Sciences)
Employment
Source: Self-asserted source
Conrado Pedebos

Education and qualifications (3)

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2013-10-30 to 2017-08-04 | PhD in Cell and Molecular Biology (Centro de Biotecnologia)
Qualification
Source: Self-asserted source
Conrado Pedebos

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2012-03-01 to 2013-10-29 | MSc in Cell and Molecular Biology (Centro de Biotecnologia)
Qualification
Source: Self-asserted source
Conrado Pedebos

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2007-03-01 to 2011-12-31 | BSc in Biomedicine
Qualification
Source: Self-asserted source
Conrado Pedebos

Works (37)

Molecular Crowding Alters the Interactions of Polymyxin Lipopeptides within the Periplasm of E. coli: Insights from Molecular Dynamics

Journal of Physical Chemistry B
2024 | Journal article
DOI: 10.1021/acs.jpcb.3c07985
EID:

2-s2.0-85187338916

Part of ISSN: 15205207 15206106
Contributors: Smith, I.P.S.; Pedebos, C.; Khalid, S.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Structure determination needs to go viral

Amino acids
2024 | Journal article
DOI: 10.1007/s00726-023-03374-2
EID:

2-s2.0-85184344751

Part of ISSN: 14382199
Contributors: de Bastos Balbe E Gutierres, M.; Pedebos, C.; Bacaicoa-Caruso, P.; Ligabue-Braun, R.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

Ureases: an overview

Ureases
2024 | Book chapter
Part of DOI: 10.1016/B978-0-323-91800-8.00011-4
EID:

2-s2.0-85190024286

ISBN: 9780323918008 9780323972000
Contributors: Pedebos, C.; Ligabue-Braun, R.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier

Polymyxin B1 in the Escherichia coli inner membrane: A complex story of protein and lipopolysaccharide-mediated insertion

Journal of Biological Chemistry
2024-10 | Journal article
DOI: 10.1016/j.jbc.2024.107754
Contributors: Dhanushka Weerakoon; Jan K. Marzinek; Conrado Pedebos; Peter J. Bond; Syma Khalid
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Complexity matters: Polymyxins and the <i>E</i>. <i>coli</i> cell envelope

Biophysical Journal
2023 | Journal article
WOSUID: WOS:000989629700867
Contributors: Smith, Iain P. S.; Pedebos, Conrado; Khalid, Syma
Source: check_circle
Web of Science Researcher Profile Sync

Computational microbiology of bacteria: Advancements in molecular dynamics simulations

Structure
2023 | Journal article
DOI: 10.1016/j.str.2023.09.012
EID:

2-s2.0-85175236530

Part of ISSN: 18784186 09692126
Contributors: Khalid, S.; Brandner, A.F.; Juraschko, N.; Newman, K.E.; Pedebos, C.; Prakaash, D.; Smith, I.P.S.; Waller, C.; Weerakoon, D.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Interactions of polymyxin B1 with the gram-negative inner membrane: A simulation study

Biophysical Journal
2023 | Journal article
WOSUID: WOS:000989629702056
Contributors: Weerakoon, Dhanushka; Marzinek, Jan K.; Bond, Peter J.; Pedebos, Conrado; Khalid, Syma
Source: check_circle
Web of Science Researcher Profile Sync

Spatial organisation of the <i>E</i>. <i>coli</i> outer membrane from multiscale computer simulations

Biophysical Journal
2023 | Journal article
WOSUID: WOS:000989629701237
Contributors: Khalid, Syma; Prakaash, Dheeraj; Pedebos, Conrado; Okada, Kiyoshiro
Source: check_circle
Web of Science Researcher Profile Sync

The solute carrier SPNS2 recruits PI(4,5)P<sub>2</sub> to synergistically regulate transport of sphingosine-1-phosphate

Molecular Cell
2023 | Journal article
DOI: 10.1016/j.molcel.2023.06.033
EID:

2-s2.0-85166523343

Part of ISSN: 10974164 10972765
Contributors: Tang, H.; Li, H.; Prakaash, D.; Pedebos, C.; Qiu, X.; Sauer, D.B.; Khalid, S.; Duerr, K.; Robinson, C.V.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Donor-strand exchange drives assembly of the TasA scaffold in Bacillus subtilis biofilms

Nature Communications
2022 | Journal article
DOI: 10.1038/s41467-022-34700-z
EID:

2-s2.0-85142289727

Part of ISSN: 20411723
Contributors: Böhning, J.; Ghrayeb, M.; Pedebos, C.; Abbas, D.K.; Khalid, S.; Chai, L.; Bharat, T.A.M.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Lipids mediate supramolecular outer membrane protein assembly in bacteria

Science Advances
2022 | Journal article
DOI: 10.1126/sciadv.adc9566
EID:

2-s2.0-85141178767

Part of ISSN: 23752548
Contributors: Webby, M.N.; Oluwole, A.O.; Pedebos, C.; Inns, P.G.; Olerinyova, A.; Prakaash, D.; Housden, N.G.; Benn, G.; Sun, D.; Hoogenboom, B.W. et al.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

Rocio Virus Encephalitis: In Silico Evidence for Drug Repurposing

Macromol
2022 | Journal article
DOI: 10.3390/macromol2010006
EID:

2-s2.0-85176591263

Part of ISSN: 26736209
Contributors: Sagini, J.P.; Arantes, P.R.; Pedebos, C.; Ligabue-Braun, R.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Simulations of the spike: molecular dynamics and SARS-CoV-2

Nature Reviews Microbiology
2022 | Journal article
DOI: 10.1038/s41579-022-00699-9
EID:

2-s2.0-85124372579

Part of ISSN: 17401534 17401526
Contributors: Pedebos, C.; Khalid, S.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

The effects of biomolecular crowding on the behaviour of polymyxin antibiotics within the <i>E</i>. <i>coli</i> cell envelope

Biophysical Journal
2022 | Journal article
WOSUID: WOS:000759523003377
Contributors: Smith, Iain P. S.; Pedebos, Conrado; Khalid, Syma
Source: check_circle
Web of Science Researcher Profile Sync

Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein

Structure
2022 | Journal article
DOI: 10.1016/j.str.2022.05.006
EID:

2-s2.0-85135496185

Part of ISSN: 18784186 09692126
Contributors: Zuzic, L.; Samsudin, F.; Shivgan, A.T.; Raghuvamsi, P.V.; Marzinek, J.K.; Boags, A.; Pedebos, C.; Tulsian, N.K.; Warwicker, J.; MacAry, P. et al.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

Computational assays of bacterial cell envelopes: doing microbiology with computers

Biophysical Reviews
2021 | Journal article
WOSUID: WOS:001082825300582
Contributors: Khalid, Syma; Pedebos, Conrado
Source: check_circle
Web of Science Researcher Profile Sync

Making it Rain: Cloud-Based Molecular Simulations for Everyone

Journal of Chemical Information and Modeling
2021 | Journal article
DOI: 10.1021/acs.jcim.1c00998
EID:

2-s2.0-85117221211

Part of ISSN: 1549960X 15499596
Contributors: Arantes, P.R.; Polêto, M.D.; Pedebos, C.; Ligabue-Braun, R.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Modifying the catalytic preference of alpha-amylase toward n-alkanes for bioremediation purposes using in silico strategies

Journal of Computational Chemistry
2021 | Journal article
DOI: 10.1002/jcc.26562
EID:

2-s2.0-85106265471

Part of ISSN: 1096987X 01928651
Contributors: Pinto, É.S.M.; Feltes, B.C.; Pedebos, C.; Dorn, M.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

Polymyxin B1 within the E. coli cell envelope: insights from molecular dynamics simulations

Biophysical Reviews
2021 | Journal article
DOI: 10.1007/s12551-021-00869-8
EID:

2-s2.0-85119680671

Part of ISSN: 18672469 18672450
Contributors: Weerakoon, D.; Petrov, K.; Pedebos, C.; Khalid, S.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Predicting the Behaviour of Antibiotics in a Virtual <i>E.coli</i> Cell Envelope

Biophysical Journal
2021 | Journal article
WOSUID: WOS:000629601401361
Contributors: Khalid, Syma; Pedebos, Conrado
Source: check_circle
Web of Science Researcher Profile Sync

Structural Basis for Silicic Acid Uptake by Higher Plants

Journal of Molecular Biology
2021 | Journal article
DOI: 10.1016/j.jmb.2021.167226
EID:

2-s2.0-85115007268

Part of ISSN: 10898638 00222836
Contributors: van den Berg, B.; Pedebos, C.; Bolla, J.R.; Robinson, C.V.; Baslé, A.; Khalid, S.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Hitchhiker's Guide to the Periplasm: Unexpected Molecular Interactions of Antibiotics in E. coli

Biophysical Reviews
2021 | Journal article
WOSUID: WOS:001082825300481
Contributors: Pedebos, Conrado; Smith, Iain; Boags, Alister; Khalid, Syma
Source: check_circle
Web of Science Researcher Profile Sync

The hitchhiker's guide to the periplasm: Unexpected molecular interactions of polymyxin B1 in E. coli

Structure
2021 | Journal article
DOI: 10.1016/j.str.2021.01.009
EID:

2-s2.0-85101703969

Part of ISSN: 18784186 09692126
Contributors: Pedebos, C.; Smith, I.P.S.; Boags, A.; Khalid, S.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 3)‎

Towards computational microbiology of bacterial cell envelopes

European Biophysics Journal
2021 | Journal article
WOSUID: WOS:000671622300130
Contributors: Khalid, Syma; Pedebos, Conrado; Smith, Iain
Source: check_circle
Web of Science Researcher Profile Sync

Assessment of structural units deletions in the archaeal oligosaccharyltransferase AglB

bioRxiv
2020 | Other
DOI: 10.1101/2020.08.18.256065
EID:

2-s2.0-85098897764

Part of ISSN: 26928205
Contributors: Pedebos, C.; Verli, H.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3

Molecular Biology and Evolution
2020 | Journal article
DOI: 10.1093/molbev/msaa060
EID:

2-s2.0-85086792731

Part of ISSN: 15371719 07374038
Contributors: Roman-Trufero, M.; Ito, C.M.; Pedebos, C.; Magdalou, I.; Wang, Y.-F.; Karimi, M.M.; Moyon, B.; Webster, Z.; Di Gregorio, A.; Azuara, V. et al.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Antimicrobial Peptide Polymyxin B1 Encounters Many Molecular Obstacles in the Periplasm <i>En Route</i> to the Inner Membrane of <i>E</i>. <i>Coli</i>

Biophysical Journal
2020 | Journal article
WOSUID: WOS:000513023201429
Contributors: Khalid, Syma; Pedebos, Conrado
Source: check_circle
Web of Science Researcher Profile Sync

The Lazy Life of Lipid-Linked Oligosaccharides in All Life Domains

Journal of Chemical Information and Modeling
2020 | Journal article
DOI: 10.1021/acs.jcim.9b00904
EID:

2-s2.0-85076539183

Part of ISSN: 1549960X 15499596
Contributors: Arantes, P.R.; Pedebos, C.; Polêto, M.D.; Pol-Fachin, L.; Verli, H.
Source: Self-asserted source
Conrado Pedebos via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Lazy Life of Lipid-Linked Oligosaccharides in All Life Domains

2019-10-07 | Other
DOI: 10.26434/chemrxiv.8170367
Contributors: Pablo Ricardo Arantes; Conrado Pedebos; Marcelo D. Poleto; Laércio Pol-Fachin; Hugo Verli
Source: check_circle
Crossref

Development of GROMOS-Compatible Parameter Set for Simulations of Chalcones and Flavonoids

Journal of Physical Chemistry B
2019-01-09 | Journal article
DOI: 10.1021/acs.jpcb.8b10139
Part of ISSN: 1520-6106
Part of ISSN: 1520-5207
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

CoCo-MD: A Simple and Effective Method for the Enhanced Sampling of Conformational Space

Journal of Chemical Theory and Computation
2019-01-08 | Journal article
DOI: 10.1021/acs.jctc.8b00657
Part of ISSN: 1549-9618
Part of ISSN: 1549-9626
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

Dynamics of DDB2-DDB1 complex under different naturally-occurring mutants in Xeroderma Pigmentosum disease

Biochimica et Biophysica Acta (BBA) - General Subjects
2018-12 | Journal article
DOI: 10.1016/j.bbagen.2018.08.007
Part of ISSN: 0304-4165
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

The role of Zn2+, dimerization and N-glycosylation in the interaction of Auxin-Binding Protein 1 (ABP1) with different auxins

Glycobiology
2017-12-01 | Journal article
DOI: 10.1093/glycob/cwx080
Part of ISSN: 0959-6658
Part of ISSN: 1460-2423
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

In silico Investigation of the PglB Active Site Reveals Transient Catalytic States and Octahedral Metal Ion Coordination

Glycobiology
2015-11 | Journal article
DOI: 10.1093/glycob/cwv053
Part of ISSN: 0959-6658
Part of ISSN: 1460-2423
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

Atomic Model and Micelle Dynamics of QS-21 Saponin

Molecules
2014-03-24 | Journal article
DOI: 10.3390/molecules19033744
Part of ISSN: 1420-3049
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

Improving the Thrombin Inhibitory Activity of Glycyrrhizin, a Triterpenic Saponin, Through a Molecular Simplification of the Carbohydrate Moiety

Chemical Biology & Drug Design
2013-12 | Journal article
DOI: 10.1111/cbdd.12204
Part of ISSN: 1747-0277
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎

Unrestrained Conformational Characterization of Stenocereus eruca Saponins in Aqueous and Nonaqueous Solvents

Journal of Natural Products
2012-06-22 | Journal article
DOI: 10.1021/np3000393
Part of ISSN: 0163-3864
Part of ISSN: 1520-6025
Source: Self-asserted source
Conrado Pedebos
grade
Preferred source (of 3)‎
How many people are using ORCID?