Personal information

oncology, gene therapy, electrochemotherapy, irradiation, immunotherapy, spheroids

Activities

Employment (1)

Institute of Oncology Ljubljana: Ljubljana, SI

1998-10-01 to present | PhD, Senior Research Associate (Department of Experimenatal Oncology)
Employment
Source: Self-asserted source
Simona Kranjc Brezar

Education and qualifications (3)

University of Ljubljana: Ljubljana, SI

2001-04-25 to 2003-02-16 | PhD (Medical Faculty, Basic Medical Sciences)
Education
Source: Self-asserted source
Simona Kranjc Brezar

University of Ljubljana: Ljubljana, SI

1998-10-01 to 2001-04-24 | MsC (Medical Faculty, Basic Medical Sciences)
Education
Source: Self-asserted source
Simona Kranjc Brezar

University of Ljubljana: Ljubljana, SI

1991-10-01 to 1998-05-26 | BsC (Biotechnical Faculty, Biology)
Education
Source: Self-asserted source
Simona Kranjc Brezar

Professional activities (1)

EACR: Nottingham, UK, GB

2022-10 to present | Member
Membership
Source: Self-asserted source
Simona Kranjc Brezar

Works (50 of 56)

Items per page:
Page 1 of 2

A carrier free delivery system of a MAGL inhibitor is effective on ovarian cancer

European Journal of Pharmaceutics and Biopharmaceutics
2024-10 | Journal article
Contributors: Stefano Palazzolo; Gloria Saorin; Giuseppe Corona; Carlotta Granchi; Tiziano Tuccinardi; Urska Kamensek; Simona Kranjc Brezar; Maja Cemazar; Vincenzo Canzonieri; Flavio Rizzolio
Source: check_circle
Crossref

An Engineered M13 Filamentous Nanoparticle as an Antigen Carrier for a Malignant Melanoma Immunotherapeutic Strategy

Viruses
2024-02 | Journal article | Author
Contributors: Nuša Brišar; Dr. Katja Šuster; Simona Kranjc Brezar; Robert Vidmar; Marko Fonović; Andrej Cör
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Gene Immunotherapy of Colon Carcinoma with IL-2 and IL-12 Using Gene Electrotransfer

International Journal of Molecular Sciences
2023-08 | Journal article | Author
Contributors: Tilen Komel; Masa Omerzel; Urska Kamensek; Katarina Znidar; Ursa Lampreht Tratar; Simona Kranjc Brezar; Klemen Dolinar; Sergej Pirkmajer; Gregor Sersa; Maja Cemazar
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Contrast-enhanced ultrasound for evaluation of tumor perfusion and outcome following treatment in a murine melanoma model

Bioelectrochemistry
2021-12 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar
grade
Preferred source (of 2)‎

Contactless delivery of plasmid encoding EGFP in vivo by high-intensity pulsed electromagnetic field

Bioelectrochemistry
2021-10 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar

Gene electrotransfer of IL-2 and IL-12 plasmids effectively eradicated murine B16.F10 melanoma

Bioelectrochemistry
2021-10 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar

Gene electrotransfer of proinflammatory chemokines CCL5 and CCL17 as a novel approach of modifying cytokine expression profile in the tumor microenvironment

Bioelectrochemistry
2021-08 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar

Results of Dynamic Contrast-Enhanced Ultrasound Correlate With Treatment Outcome in Canine Neoplasia Treated With Electrochemotherapy and Interleukin-12 Plasmid Electrotransfer

Frontiers in Veterinary Science
2021-05-20 | Journal article
Part of ISSN: 2297-1769
Source: Self-asserted source
Simona Kranjc Brezar

Synergistic effect of cisplatin chemotherapy combined with fractionated radiotherapy regimen in HPV-positive and HPV-negative experimental pharyngeal squamous cell carcinoma

Scientific Reports
2020-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Simona Kranjc Brezar

Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response

Vaccines
2020-03-19 | Journal article
Part of ISSN: 2076-393X
Source: Self-asserted source
Simona Kranjc Brezar

Electrotransfer of siRNA to Silence Enhanced Green Fluorescent Protein in Tumor Mediated by a High Intensity Pulsed Electromagnetic Field

Vaccines
2020-01-27 | Journal article
Part of ISSN: 2076-393X
Source: Self-asserted source
Simona Kranjc Brezar

Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts

Oncology Reports
2019-01-09 | Journal article
Part of ISSN: 1021-335X
Part of ISSN: 1791-2431
Source: Self-asserted source
Simona Kranjc Brezar

Electrochemotherapy with cisplatin or bleomycin in head and neck squamous cell carcinoma: Improved effectiveness of cisplatin in HPV-positive tumors

Bioelectrochemistry
2018-10 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar

APS8 Delays Tumor Growth in Mice by Inducing Apoptosis of Lung Adenocarcinoma Cells Expressing High Number of α7 Nicotinic Receptors

Marine Drugs
2018-10-03 | Journal article
Part of ISSN: 1660-3397
Source: Self-asserted source
Simona Kranjc Brezar

Vascularization of the tumours affects the pharmacokinetics of bleomycin and the effectiveness of electrochemotherapy

Basic & Clinical Pharmacology & Toxicology
2018-09 | Journal article
Part of ISSN: 1742-7835
Source: Self-asserted source
Simona Kranjc Brezar

Dose-Modifying Factor of Radiation Therapy with Concurrent Cisplatin Treatment in HPV-Positive Squamous Cell Carcinoma: A Preclinical Study

Radiation Research
2018-04-13 | Journal article
Part of ISSN: 0033-7587
Source: Self-asserted source
Simona Kranjc Brezar

Comparable effectiveness and immunomodulatory actions of oxaliplatin and cisplatin in electrochemotherapy of murine melanoma

Bioelectrochemistry
2018-02 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar

In vitro and in vivo evaluation of electrochemotherapy with trans-platinum analogue trans-[PtCl2(3-Hmpy)2]

Radiology and Oncology
2017-09-14 | Journal article
Part of ISSN: 1581-3207
Source: Self-asserted source
Simona Kranjc Brezar

Addition of 2-(ethylamino)acetonitrile group to nitroxoline results in significantly improved anti-tumor activity in vitro and in vivo

Oncotarget
2017-08-29 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Simona Kranjc Brezar

Electrotransfer parameters as a tool for controlled and targeted gene expression in skin

Molecular Therapy - Nucleic Acids
2016 | Journal article
Part of ISSN: 2162-2531
Source: Self-asserted source
Simona Kranjc Brezar

Improved Protective Effect of Umbilical Cord Stem Cell Transplantation on Cisplatin-Induced Kidney Injury in Mice Pretreated with Antithymocyte Globulin

Stem Cells International
2016 | Journal article
Part of ISSN: 1687-966X
Part of ISSN: 1687-9678
Source: Self-asserted source
Simona Kranjc Brezar

Cytotoxic trans-platinum(II) complex with 3-hydroxymethylpyridine: Synthesis, X-ray structure and biological activity evaluation

Journal of Inorganic Biochemistry
2016-08 | Journal article
Part of ISSN: 0162-0134
Source: Self-asserted source
Simona Kranjc Brezar

Tumor radiosensitization by gene therapy against endoglin

Cancer Gene Therapy
2016-07 | Journal article
Part of ISSN: 0929-1903
Part of ISSN: 1476-5500
Source: Self-asserted source
Simona Kranjc Brezar

Electrochemotherapy by pulsed electromagnetic field treatment (PEMF) in mouse melanoma B16F10 in vivo

Radiology and Oncology
2016-02-16 | Journal article
Part of ISSN: 1581-3207
Source: Self-asserted source
Simona Kranjc Brezar

Endoglin (CD105) Silencing Mediated by shRNA Under the Control of Endothelin-1 Promoter for Targeted Gene Therapy of Melanoma

Molecular Therapy - Nucleic Acids
2015 | Journal article
Part of ISSN: 2162-2531
Source: Self-asserted source
Simona Kranjc Brezar

Improved Specificity of Gene Electrotransfer to Skin Using pDNA Under the Control of Collagen Tissue-Specific Promoter

The Journal of Membrane Biology
2015-10 | Journal article
Part of ISSN: 0022-2631
Part of ISSN: 1432-1424
Source: Self-asserted source
Simona Kranjc Brezar

Gene electrotransfer of plasmid AMEP, an integrin-targeted therapy, has antitumor and antiangiogenic action in murine B16 melanoma

Gene Therapy
2015-07 | Journal article
Part of ISSN: 0969-7128
Part of ISSN: 1476-5462
Source: Self-asserted source
Simona Kranjc Brezar

Endoglin Silencing has Significant Antitumor Effect on Murine Mammary Adenocarcinoma Mediated by Vascular Targeted Effect

Current Gene Therapy
2015-03-28 | Journal article
Part of ISSN: 1566-5232
Source: Self-asserted source
Simona Kranjc Brezar

Adjuvant TNF-α therapy to electrochemotherapy with intravenous cisplatin in murine sarcoma exerts synergistic antitumor effectiveness

Radiology and Oncology
2015-03-01 | Journal article
Part of ISSN: 1581-3207
Source: Self-asserted source
Simona Kranjc Brezar

Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma

BMC Cancer
2013-12 | Journal article
Part of ISSN: 1471-2407
Source: Self-asserted source
Simona Kranjc Brezar

Multiple Delivery of siRNA against Endoglin into Murine Mammary Adenocarcinoma Prevents Angiogenesis and Delays Tumor Growth

PLoS ONE
2013-03-05 | Journal article
Part of ISSN: 1932-6203
Source: Self-asserted source
Simona Kranjc Brezar

Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity

Radiology and Oncology
2012-10-01 | Journal article
Part of ISSN: 1581-3207
Part of ISSN: 1318-2099
Source: Self-asserted source
Simona Kranjc Brezar

Muscle gene electrotransfer is increased by the antioxidant tempol in mice

Gene Therapy
2012-03 | Journal article
Part of ISSN: 0969-7128
Part of ISSN: 1476-5462
Source: Self-asserted source
Simona Kranjc Brezar

Irradiation, Cisplatin, and 5-Azacytidine Upregulate Cytomegalovirus Promoter in Tumors and Muscles: Implementation of Non-invasive Fluorescence Imaging

Molecular Imaging and Biology
2011-02 | Journal article
Part of ISSN: 1536-1632
Part of ISSN: 1860-2002
Source: Self-asserted source
Simona Kranjc Brezar

Electrochemotherapy of Mouse Sarcoma Tumors Using Electric Pulse Trains with Repetition Frequencies of 1 Hz and 5 kHz

The Journal of Membrane Biology
2010-07 | Journal article
Part of ISSN: 0022-2631
Part of ISSN: 1432-1424
Source: Self-asserted source
Simona Kranjc Brezar

The influence of skeletal muscle anisotropy on electroporation: in vivo study and numerical modeling

Medical & Biological Engineering & Computing
2010-07 | Journal article
Part of ISSN: 0140-0118
Part of ISSN: 1741-0444
Source: Self-asserted source
Simona Kranjc Brezar

MicroRNAs targeting mutant K-ras by electrotransfer inhibit human colorectal adenocarcinoma cell growth in vitro and in vivo

Cancer Gene Therapy
2010-06 | Journal article
Part of ISSN: 0929-1903
Part of ISSN: 1476-5500
Source: Self-asserted source
Simona Kranjc Brezar

The influence of electroporation on cytotoxicity of anticancer ruthenium(III) complex KP1339 in vitro and in vivo.

Anticancer research
2010-06-01 | Journal article
Source: Self-asserted source
Simona Kranjc Brezar

Study of radiation induced changes of phosphorus metabolism in mice by 31P NMR spectroscopy

Radiology and Oncology
2010-01-01 | Journal article
Part of ISSN: 1581-3207
Part of ISSN: 1318-2099
Source: Self-asserted source
Simona Kranjc Brezar

Controlled systemic release of interleukin-12 after gene electrotransfer to muscle for cancer gene therapy alone or in combination with ionizing radiation in murine sarcomas

The Journal of Gene Medicine
2009-12 | Journal article
Part of ISSN: 1099-498X
Part of ISSN: 1521-2254
Source: Self-asserted source
Simona Kranjc Brezar

Radiosensitizing Effect of Electrochemotherapy in a Fractionated Radiation Regimen in Radiosensitive Murine Sarcoma and Radioresistant Adenocarcinoma Tumor Model

Radiation Research
2009-12 | Journal article
Part of ISSN: 0033-7587
Part of ISSN: 1938-5404
Source: Self-asserted source
Simona Kranjc Brezar

Control by pulse parameters of DNA electrotransfer into solid tumors in mice

Gene Therapy
2009-05 | Journal article
Part of ISSN: 0969-7128
Part of ISSN: 1476-5462
Source: Self-asserted source
Simona Kranjc Brezar

Gene Electrotransfer into Murine Skeletal Muscle: A Systematic Analysis of Parameters for Long-term Gene Expression

Technology in Cancer Research & Treatment
2008-04 | Journal article
Part of ISSN: 1533-0346
Part of ISSN: 1533-0338
Source: Self-asserted source
Simona Kranjc Brezar

Vascular disrupting action of electroporation and electrochemotherapy with bleomycin in murine sarcoma

British Journal of Cancer
2008-01 | Journal article
Part of ISSN: 0007-0920
Part of ISSN: 1532-1827
Source: Self-asserted source
Simona Kranjc Brezar

The effect of the histological properties of tumors on transfection efficiency of electrically assisted gene delivery to solid tumors in mice

Gene Therapy
2007-09 | Journal article
Part of ISSN: 0969-7128
Part of ISSN: 1476-5462
Source: Self-asserted source
Simona Kranjc Brezar

Electrogene Therapy withp53of Murine Sarcomas Alone or Combined with Electrochemotherapy Using Cisplatin

DNA and Cell Biology
2006-12 | Journal article
Part of ISSN: 1044-5498
Part of ISSN: 1557-7430
Source: Self-asserted source
Simona Kranjc Brezar

The endothelial cytoskeleton as a target of electroporation-based therapies

Molecular Cancer Therapeutics
2006-12 | Journal article
Part of ISSN: 1535-7163
Part of ISSN: 1538-8514
Source: Self-asserted source
Simona Kranjc Brezar

Sequence and Time Dependence of Transfection Efficiency of Electrically- Assisted Gene Delivery to Tumors in Mice

Current Drug Delivery
2006-01-01 | Journal article
Part of ISSN: 1567-2018
Source: Self-asserted source
Simona Kranjc Brezar

Radiosensitising effect of electrochemotherapy with bleomycin in LPB sarcoma cells and tumors in mice

BMC Cancer
2005-12 | Journal article
Part of ISSN: 1471-2407
Source: Self-asserted source
Simona Kranjc Brezar

The effect of high frequency electric pulses on muscle contractions and antitumor efficiency in vivo for a potential use in clinical electrochemotherapy

Bioelectrochemistry
2005-02 | Journal article
Part of ISSN: 1567-5394
Source: Self-asserted source
Simona Kranjc Brezar
Items per page:
Page 1 of 2

Peer review (4 reviews for 4 publications/grants)

Review activity for Bioelectromagnetics. (1)
Review activity for Cancers. (1)
Review activity for Oncology Letters. (1)
Review activity for PloS one. (1)