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Loop profile: 572689

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Education and qualifications (2)

Stanford Health Care: Stanford, California, US

2023-06-25 to present | MD, PhD (Internal Medicine)
Education
Source: Self-asserted source
Hannah Knochelmann

Medical University of South Carolina: Charleston, SC, US

2015-08-01 to present (Microbiology & Immunology)
Education
Source: Self-asserted source
Hannah Knochelmann

Funding (1)

Determining mechanisms of enhanced antitumor efficacy of four-day expanded Th17 cells for adoptive transfer

2019-09 to 2023-07 | Grant
National Cancer Institute (Md., Md., US)
GRANT_NUMBER:

F30 CA243307
Source: Self-asserted source
Hannah Knochelmann

Works (19)

Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells

Journal for ImmunoTherapy of Cancer
2024-06 | Journal article
DOI: 10.1136/jitc-2023-008715
Contributors: Megen C Wittling; Hannah M Knochelmann; Megan M Wyatt; Guillermo O Rangel Rivera; Anna C Cole; Gregory B Lesinski; Chrystal M Paulos
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Crossref

Data from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.c.7002671
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Data from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.c.7002671.v1
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

Cancer Research
2024-01-02 | Journal article
DOI: 10.1158/0008-5472.CAN-23-0801
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Supplementary Data from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.24924128
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Crossref

Supplementary Data from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.24924128.v1
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Table of reagents from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.24924125
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Crossref

Table of reagents from Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity

2024-01-02 | Preprint
DOI: 10.1158/0008-5472.24924125.v1
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Bülent Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Soundharya Kumaresan; Jessica E. Thaxton; Gregory B. Lesinski et al.
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Crossref

Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells

2023-12-18 | Preprint
DOI: 10.1101/2023.12.18.572179
Contributors: Megen C. Wittling; Hannah M. Knochelmann; Megan M. Wyatt; Guillermo O. Rangel Rivera; Anna C. Cole; Gregory B. Lesinski; Chrystal M. Paulos
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Crossref

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner

JCI Insight
2023-04-24 | Journal article
DOI: 10.1172/jci.insight.155006
Contributors: Michael Brandon Ware; Maggie Phillips; Christopher McQuinn; Mohammad Y. Zaidi; Hannah M. Knochelmann; Emily Greene; Brian Robinson; Cameron J. Herting; Thomas A. Mace; Zhengjia Chen et al.
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Crossref

The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner

2023-03-10 | Preprint
DOI: 10.1101/2023.03.08.531589
Contributors: Guillermo O. Rangel Rivera; Connor J. Dwyer; Hannah M. Knochelmann; Aubrey S. Smith; Arman Aksoy; Anna C. Cole; Megan M. Wyatt; Jessica E. Thaxton; Gregory B. Lesinski; Chrystal M. Paulos
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Crossref

Discovering tumor-reactive T-cell receptors through single-cell sequencing of tumor-infiltrating lymphocytes

2021-12-01 | Other
DOI: 10.1101/2021.11.30.470597
Contributors: Elinor Gottschalk; Bulent Arman Aksoy; Pinar Aksoy; Marzena Swiderska-syn; Caroline Mart; Linda Macpherson; Martin Romeo; Aubrey Smith; Hannah Knochelmann; Chrystal Paulos et al.
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Crossref

Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma

Cell Reports Medicine
2021-10 | Journal article
DOI: 10.1016/j.xcrm.2021.100426
Contributors: Hannah M. Knochelmann; Joshua D. Horton; Sixue Liu; Kent Armeson; John M. Kaczmar; Megan M. Wyatt; Mary S. Richardson; Shirley H. Lomeli; Ying Xiong; Evan M. Graboyes et al.
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Crossref

B cells imprint adoptively transferred CD8+T cells with enhanced tumor immunity

2021-03-17 | Preprint
DOI: 10.1101/2021.03.16.435714
Contributors: Aubrey S. Smith; Hannah M. Knochelmann; Megan M. Wyatt; Guillermo O. Rangel Rivera; Amalia M. Rivera-Reyes; Connor J. Dwyer; David M. Neskey; Mark P. Rubinstein; Bei Liu; Jessica E. Thaxton et al.
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Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

2021-02-05 | Preprint
DOI: 10.1101/2021.02.04.429846
Contributors: HM Knochelmann; AM Rivera-Reyes; MM Wyatt; AS Smith; R Chamness; CJ Dwyer; M Bobian; GO Rangel Rivera; JD Horton; M Lilly et al.
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Crossref

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

OncoImmunology
2021-01 | Journal article
DOI: 10.1080/2162402X.2021.1959101
Contributors: Hannah M Knochelmann; Amalia M Rivera-Reyes; Megan M Wyatt; Aubrey S Smith; Reilley Chamness; Connor J Dwyer; Michael Bobian; Guillermo O Rangel Rivera; Joshua D Horton; Michael Lilly et al.
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Identification of human CD4 + T cell populations with distinct antitumor activity

Science Advances
2020-07-03 | Journal article
DOI: 10.1126/sciadv.aba7443
Contributors: Michelle H. Nelson; Hannah M. Knochelmann; Stefanie R. Bailey; Logan W. Huff; Jacob S. Bowers; Kinga Majchrzak-Kuligowska; Megan M. Wyatt; Mark P. Rubinstein; Shikhar Mehrotra; Michael I. Nishimura et al.
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Crossref

The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020

Cancers
2020-06-11 | Journal article
DOI: 10.3390/cancers12061543
Contributors: Flora Yan; Hannah M. Knochelmann; Patrick F. Morgan; John M. Kaczmar; David M. Neskey; Evan M. Graboyes; Shaun A. Nguyen; Besim Ogretmen; Anand K. Sharma; Terry A. Day
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Identification of human CD4+T cell populations with distinct antitumor activity

2020-01-02 | Preprint
DOI: 10.1101/2019.12.31.891317
Contributors: Michelle H. Nelson; Hannah M. Knochelmann; Stefanie R. Bailey; Logan W. Huff; Jacob S. Bowers; Kinga Majchrzak; Megan M. Wyatt; Mark P. Rubinstein; Shikhar Mehrotra; Michael I. Nishimura et al.
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