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SciProfiles: 303935

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Employment (7)

Institut Pasteur: Paris, Paris, FR

2017-10-01 to present | Senior research engineer (Microbiology)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

DBV Technologies: Montrouge, Île-de-France, FR

2015-12-07 to 2017-09-30 | Manager, Scientific and Medical writing (Research and Develoment)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

Medicines and Healthcare Products Regulatory Agency: London, London, GB

2006-05-28 to 2015-09-15 | Senior Scientific Officer (Microbiology)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

Cardiff University School of Medicine: Cardiff, Cardiff, GB

2005-01-05 to 2006-05-23 | Resarch Associate (Pharmacology)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

Therapharm Research : Boulogne-Billancourt, Ile de France, FR

2003-01-09 to 2005-01-09 | Project leader, Scientifc and Medical writer (Resarch and development)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

SGS aster cephac: Paris, Île-de-France, FR

2001-01-05 to 2003-01-02 | Mecical writer-Project Officer (Research and Development)
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

Commissariat a l'energie atomique et aux energies alternatives Centre de Saclay: Gif-sur-Yvette, Île-de-France, FR

1997-01-09 to 2000-01-08 | Post-doctoral researcher, Positron emission tomograhy imaging (Direction des Sciences du Vivant, SHFJ )
Employment
Source: Self-asserted source
Christine Rasetti-Escargueil

Education and qualifications (2)

Paris Descartes University: Paris, Paris, FR

1991-09-15 to 1995-09-28 | PhD Molecular Pharmacology (Pharmacology)
Education
Source: Self-asserted source
Christine Rasetti-Escargueil

Université Paris-Sud, Pharmaceutical and Biological sciences: Paris XI, Ile de France, FR

1985-09-15 to 1990-09-15 | Degree in Pharmacy, Pharmacology Master (Pharmacology research, Industry option)
Education
Source: Self-asserted source
Christine Rasetti-Escargueil

Professional activities (2)

The Royal Society of Medicine: London, London, GB

2010-01-03 to 2015-01-03 | Associate fellow
Membership
Source: Self-asserted source
Christine Rasetti-Escargueil

Microscience Microscopy Congress June 2012: Manchester, Manchester, GB

2012-06-07 | Poster awarded First prize (A correlative light and electron microscopy study on the up-take of a novel multi-modular botulinum toxin by neuronal cells )
Distinction
Source: Self-asserted source
Christine Rasetti-Escargueil

Funding (3)

AntiBotABE Neutralizing antibodies against botulinum toxins A,B,E

2010-09 to 2015-09 | Grant
FP7 Security (Brussels, Brussels, BE)
GRANT_NUMBER: ANTIBOTABE_CA_28-01-2010
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of cell based assays as replacement assays for Botulinum toxins and antitoxins

2010-09 to 2014-08 | Grant
National Centre for the Replacement Refinement and Reduction of Animals in Research (London, London, GB)
GRANT_NUMBER:

94812
Source: Self-asserted source
Christine Rasetti-Escargueil

Effects of septic shock mediators on the constriction induced by angiotensin II

1995-01 to 1995-12 | Award
Fondation pour la Recherche Médicale (Paris Cedex 15, FR)
Source: Self-asserted source
Christine Rasetti-Escargueil

Works (38)

Development of Effective Medical Countermeasures Against the Main Biowarfare Agents: The Importance of Antibodies

Microorganisms
2024-12 | Journal article | Author
DOI: 10.3390/microorganisms12122622
Contributors: Arnaud AVRIL; Sophie Guillier; Christine Rasetti-Escargueil
Source: check_circle
Multidisciplinary Digital Publishing Institute

Embracing the Versatility of Botulinum Neurotoxins in Conventional and New Therapeutic Applications

Toxins
2024-06 | Journal article | Author
DOI: 10.3390/toxins16060261
Contributors: Christine Rasetti-Escargueil; Stefano Palea
Source: check_circle
Multidisciplinary Digital Publishing Institute

Medical Countermeasures against Ricin Intoxication

Toxins
2023-01 | Journal article | Author
DOI: 10.3390/toxins15020100
Contributors: Christine Rasetti-Escargueil; Arnaud AVRIL
Source: check_circle
Multidisciplinary Digital Publishing Institute

Recent Developments in Botulinum Neurotoxins Detection

Microorganisms
2022-05 | Journal article | Author
DOI: 10.3390/microorganisms10051001
Contributors: Christine Rasetti-Escargueil; Michel Popoff
Source: check_circle
Multidisciplinary Digital Publishing Institute

Engineering Botulinum Neurotoxins for Enhanced Therapeutic Applications and Vaccine Development

Toxins
2020-12 | Journal article | Author
DOI: 10.3390/toxins13010001
Contributors: Christine Rasetti-Escargueil; Michel Popoff
Source: check_circle
Multidisciplinary Digital Publishing Institute

Toxemia in Human Naturally Acquired Botulism.

Toxins
2020-11-13 | Journal article
DOI: 10.3390/toxins12110716
PMID: 33202855
Source: Self-asserted source
Christine Rasetti-Escargueil

Human Botulism in France, 1875-2016.

Toxins
2020-05-21 | Journal article
DOI: 10.3390/toxins12050338
PMID: 32455538
PMC: PMC7291226
Source: Self-asserted source
Christine Rasetti-Escargueil

Public Health Risk Associated with Botulism as Foodborne Zoonoses.

Toxins
2019-12-30 | Journal article
DOI: 10.3390/toxins12010017
PMID: 31905908
PMC: PMC7020394
Source: Self-asserted source
Christine Rasetti-Escargueil

Antibodies and Vaccines against Botulinum Toxins: Available Measures and Novel Approaches.

Toxins
2019-09-12 | Journal article
DOI: 10.3390/toxins11090528
PMID: 31547338
PMC: PMC6783819
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of innovative BoNT antibodies and progress toward harmonization of the detection of BoNT toxins

Interagency Botulism Research Coordinating Committee, Chicago, USA
2018-10-28 | Lecture
Source: Self-asserted source
Christine Rasetti-Escargueil

Variability of Botulinum Toxins: Challenges and Opportunities for the Future.

Toxins
2018-09-13 | Journal article
DOI: 10.3390/toxins10090374
PMID: 30217070
PMC: PMC6162648
Source: Self-asserted source
Christine Rasetti-Escargueil

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

Toxins
2017-10 | Journal article
DOI: 10.3390/toxins9100309
Source: check_circle
Multidisciplinary Digital Publishing Institute

Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody.

Toxins
2016-09-12 | Journal article
DOI: 10.3390/toxins8090257
PMID: 27626446
PMC: PMC5037483
Source: Self-asserted source
Christine Rasetti-Escargueil
grade
Preferred source (of 2)‎

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B.

PloS one
2016-08-25 | Journal article
DOI: 10.1371/journal.pone.0161446
PMID: 27560688
PMC: PMC4999263
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E.

PloS one
2015-10-06 | Journal article
DOI: 10.1371/journal.pone.0139905
PMID: 26440796
PMC: PMC4595074
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B.

mAbs
2015-09-18 | Journal article
DOI: 10.1080/19420862.2015.1082016
PMID: 26381852
PMC: PMC4966489
Source: Self-asserted source
Christine Rasetti-Escargueil

Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain.

BMC biotechnology
2015-09-17 | Journal article
DOI: 10.1186/s12896-015-0206-0
PMID: 26382731
PMC: PMC4574468
Source: Self-asserted source
Christine Rasetti-Escargueil

Application of stem cells and induced pluripotent stem cells for the development of cell-based assays for Botulinum toxins and antitoxins MRC-NC3R project up-date

Stem cells symposium National Institute of Biological Standards and Controls , London 2015
2015-02-28 | Lecture
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library.

mAbs
2014-01-09 | Journal article
DOI: 10.4161/mabs.27773
PMID: 24492304
PMC: PMC3984333
Source: Self-asserted source
Christine Rasetti-Escargueil

Synthetic self-assembling clostridial chimera for modulation of sensory functions.

Bioconjugate chemistry
2013-09-20 | Journal article
DOI: 10.1021/bc4003103
PMID: 24011174
PMC: PMC3901392
Source: Self-asserted source
Christine Rasetti-Escargueil

Biologically relevant alternative cell-based sandwich-ELISA assay for detection and quantification of botulinum toxins

2013-09-17 | Journal article
DOI: 10.1504/TBJ.2013.05566
Source: Self-asserted source
Christine Rasetti-Escargueil

Clostridium botulinum: a spore forming organism and a challenge to food safety

Nova Science Series
2012-12-31 | Book
ISBN: 978-1-61470-653-3
Source: Self-asserted source
Christine Rasetti-Escargueil

Effects of Botulinum toxin on neuronal communication: Converging evidences of central effects

2012-12-31 | Book chapter
Part of ISBN: 9781622571857
Source: Self-asserted source
Christine Rasetti-Escargueil

Integrated Approach used by Government Agencies and Industry to Protect the Consumer

2012-12-31 | Book chapter
Part of ISBN: 978-1-61470-653-3
Source: Self-asserted source
Christine Rasetti-Escargueil

Recent developments of AntibotABE project: identification of neutralizing small chain fragment antibodies directed against botulinum A and B toxins

Toxins 2012 meeting: Basic Science and Clinical Aspects of Botulinum and Other Neurotoxins, Miami, USA
2012-12-08 | Lecture
Source: Self-asserted source
Christine Rasetti-Escargueil

Development of in vitro functional replacement assays for Botulinum toxin and antitoxin preparations”,

FDA Food and Drug Agency USA
2011-11-28 | Lecture
Source: Self-asserted source
Christine Rasetti-Escargueil

Enhanced sensitivity to Botulinum type A neurotoxin of human neuroblastoma SH-SY5Y cells after differentiation into mature neuronal cells

The Botulinum Journal
2011-07-15 | Journal article
DOI: 10.1504/TBJ.2011.041814
Source: Self-asserted source
Christine Rasetti-Escargueil

Enhanced sensitivity to Botulinum type A neurotoxin of human neuroblastoma SH-SY5Y cells after differentiation into mature neuronal cells

Laboratory of Molecular Biology in Cambridge, University of Cambridge
2011-05-17 | Lecture
Source: Self-asserted source
Christine Rasetti-Escargueil

Phrenic nerve-hemidiaphragm as a highly sensitive replacement assay for determination of functional botulinum toxin antibodies.

Toxicon : official journal of the International Society on Toxinology
2011-04-13 | Journal article
DOI: 10.1016/j.toxicon.2011.04.003
PMID: 21513727
Source: Self-asserted source
Christine Rasetti-Escargueil

Measurement of botulinum types A, B and E neurotoxicity using the phrenic nerve-hemidiaphragm: improved precision with in-bred mice.

Toxicon : official journal of the International Society on Toxinology
2009-04-01 | Journal article
DOI: 10.1016/j.toxicon.2009.01.019
PMID: 19673096
Source: Self-asserted source
Christine Rasetti-Escargueil

Pharmacokinetic profiles of two tablet formulations of piroxicam.

International journal of pharmaceutics
2005-05-01 | Journal article
DOI: 10.1016/j.ijpharm.2005.02.006
PMID: 15847998
Source: Self-asserted source
Christine Rasetti-Escargueil

Preliminary evaluation of 2-(4-(3-(tert-butylamino)-2-Hydroxypropoxy) phenyl-3-Methyl-6-Methoxy-4(3h)-Quinazolinone (+HX-CH44) as a selective beta 1-adrenoceptor ligand for PET

Nuclear Medicine and Biology
1999-12-31 | Conference paper
PMID: 10096509
Source: Self-asserted source
Christine Rasetti-Escargueil

MIBG Imaging in heart failure

Heart failure
1998-12-31 | Journal article
PMID: 10007867764
Source: Self-asserted source
Christine Rasetti-Escargueil

Effects of TNF and Interleukin-1 on the constriction induced by angiotensin II in rat aorta

Journal of Applied Physiology
1996-12-31 | Journal article
PMID: 8806891
Source: Self-asserted source
Christine Rasetti-Escargueil

Differences between cytokine effects in the microcirculation of the rat.

The American journal of physiology
1996-09-01 | Journal article
DOI: 10.1152/ajpheart.1996.271.3.h1186
PMID: 8853359
Source: Self-asserted source
Christine Rasetti-Escargueil

Short exposure to endotoxin increases the constriction induced by angiotensin II in rat aorta

Journal of Applied Physiology
1995-12-31 | Journal article
PMID: 8847278
Source: Self-asserted source
Christine Rasetti-Escargueil

Angiotensin-I converting enzyme in the three tunicae of the rat aorta: Expression in smooth muscle and effect of renovascular hypertension

American Journal of Physiology
1994-12-31 | Journal article
PMID: 7977808
Source: Self-asserted source
Christine Rasetti-Escargueil

Magnesium modulates endothelial dysfunction produced by elevated glucose incubation

Journal of Cardiovascular Pharmacology
1994-12-31 | Journal article
PMID: PMID: 7528304
Source: Self-asserted source
Christine Rasetti-Escargueil

Peer review (4 reviews for 4 publications/grants)

Review activity for Environmental science and pollution research international (1)
Review activity for F1000Research. (1)
Review activity for Immunologic research. (1)
Review activity for PloS one. (1)
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