Personal information

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Employment (2)

Charles University: Pilsen, CZ

2014 to present | Postdoc (Faculty of Medicine in Pilsen, Biomedical Center, Laboratory of Pharmacogenomics)
Employment
Source: Self-asserted source
Viktor Hlavac

National Institute of Public Health: Prague, CZ

2010 to present | Postdoc (Department of Toxicogenomics)
Employment
Source: Self-asserted source
Viktor Hlavac

Education and qualifications (3)

Charles University: Prague, CZ

2011 to 2017 | PhD (Third Faculty of Medicine)
Education
Source: Self-asserted source
Viktor Hlavac

Institute for Postgraduate Medical Education: Prague, CZ

2011 to 2012 | Acredited qualification course (Professional medical laboratory methods)
Qualification
Source: Self-asserted source
Viktor Hlavac

Masaryk University: Brno, CZ

1998 to 2005 | MSc (Faculty of Science, Molecular Biology and Genetics)
Education
Source: Self-asserted source
Viktor Hlavac

Works (27)

Targeted DNA sequencing of high‐grade serous ovarian carcinoma reveals association of TP53 mutations with platinum resistance when combined with gene expression

International Journal of Cancer
2024-07 | Journal article
Contributors: Petr Holý; Viktor Hlaváč; Karolína Šeborová; Simona Šůsová; Tereza Tesařová; Lukáš Rob; Martin Hruda; Jiří Bouda; Alena Bartáková; Marcela Mrhalová et al.
Source: check_circle
Crossref

Targeted panel sequencing of pharmacogenes and oncodrivers in colorectal cancer patients reveals genes with prognostic significance

Human Genomics
2024-07-19 | Journal article
Contributors: Lucie Heczko; Václav Liška; Ondřej Vyčítal; Ondřej Fiala; Simona Šůsová; Viktor Hlaváč; Pavel Souček
Source: check_circle
Crossref

Genes divided according to the relative position of the longest intron show increased representation in different KEGG pathways

BMC Genomics
2024-06-28 | Journal article
Contributors: Pavel Dvorak; Viktor Hlavac; Vojtech Hanicinec; Bhavana Hemantha Rao; Pavel Soucek
Source: check_circle
Crossref

The longest intron rule

2023-10-04 | Preprint
Contributors: Pavel Dvorak; Viktor Hlavac; Vojtech Hanicinec; Bhavana Hemantha Rao; Pavel Soucek
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Crossref

The Potential of Exome Sequencing of Paired Colorectal Tumors and Synchronous Liver Metastases to Improve Treatment

Pharmacogenomics
2023-08 | Journal article
Contributors: Viktor Hlaváč; Petr Holý; Pavel Souček
Source: check_circle
Crossref

Exome Sequencing of Paired Colorectal Carcinomas and Synchronous Liver Metastases for Prognosis and Therapy Prediction

JCO Precision Oncology
2023-05 | Journal article
Contributors: Viktor Hlaváč; Lenka Červenková; Simona Šůsová; Petr Holý; Václav Liška; Ondřej Vyčítal; Ondřej Šorejs; Ondřej Fiala; Ondřej Daum; Pavel Souček
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Crossref

Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy

Life Science Alliance
2022-12 | Journal article
Contributors: Viktor Hlaváč; Petr Holý; Radka Václavíková; Lukáš Rob; Martin Hruda; Marcela Mrhalová; Petr Černaj; Jiří Bouda; Pavel Souček
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Crossref

Laser Capture Microdissection: A Gear for Pancreatic Cancer Research

International Journal of Molecular Sciences
2022-11-23 | Journal article
Contributors: Bhavana Hemantha Rao; Pavel Souček; Viktor Hlaváč
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Crossref
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Preferred source (of 2)‎

Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response

International Journal of Molecular Sciences
2021-03 | Journal article | Author
Contributors: Viktor Hlavac; Radka Václavíková; Veronika Brynychová; Pavel Ostašov; Renata Koževnikovová; Katerina Kopečková; David Vrana; Jiří Gatěk; Pavel Soucek
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

SLC46A1 Haplotype with Predicted Functional Impact has Prognostic Value in Breast Carcinoma

Molecular Diagnosis & Therapy
2021-01 | Journal article
Contributors: Viktor Hlavac; Radka Vaclavikova; Veronika Brynychova; Pavel Dvorak; Katerina Elsnerova; Renata Kozevnikovova; Karel Raus; Katerina Kopeckova; Sona Mestakova; David Vrana et al.
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Crossref

Role of Genetic Variation in ABC Transporters in Breast Cancer Prognosis and Therapy Response

International Journal of Molecular Sciences
2020-12 | Journal article | Author
Contributors: Viktor Hlavac; Radka Václavíková; Veronika Brynychová; Renata Koževnikovová; Katerina Kopečková; David Vrana; Jiří Gatěk; Pavel Soucek
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

5′ Untranslated Region Elements Show High Abundance and Great Variability in Homologous ABCA Subfamily Genes

International Journal of Molecular Sciences
2020-11 | Journal article | Author
Contributors: Pavel Dvorak; Viktor Hlavac; Pavel Soucek
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Targeted Sequencing of Pancreatic Adenocarcinomas from Patients with Metachronous Pulmonary Metastases

Genes
2020-11 | Journal article | Author
Contributors: Viktor Hlavac; Beatrice Mohelnikova-Duchonova; Martin Loveček; Jiri Ehrmann; Veronika Brynychova; Kateřina Urban; Pavel Soucek
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Pharmacogenomics to Predict Tumor Therapy Response: A Focus on ATP-Binding Cassette Transporters and Cytochromes P450

Journal of Personalized Medicine
2020-08 | Journal article | Author
Contributors: Viktor Hlavac; Petr Holý; Pavel Soucek
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients

Cancers
2018-12 | Journal article | Author
Contributors: Viktor Hlavac; Maria Kovacova; Katerina Elsnerova; Veronika Brynychova; Renata Kozevnikovova; Karel Raus; Katerina Kopeckova; Sona Mestakova; David Vrana; Jiri Gatek et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer

International Journal of Molecular Sciences
2018-03 | Journal article
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Downregulation of ABC transporters in non-neoplastic tissues confers better prognosis for pancreatic and colorectal cancer patients

Journal of Cancer
2017 | Journal article
EID:

2-s2.0-85025163670

Contributors: Dvorak, P.; Hlavac, V.; Mohelnikova-Duchonova, B.; Liska, V.; Pesta, M.; Soucek, P.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Transcript expression and genetic variability analysis of caspases in breast carcinomas suggests CASP9 as the most interesting target

Clinical Chemistry and Laboratory Medicine
2017 | Journal article
EID:

2-s2.0-84998694303

Contributors: Brynychova, V.; Hlavac, V.; Ehrlichova, M.; Vaclavikova, R.; Nemcova-Furstova, V.; Pecha, V.; Trnkova, M.; Mrhalova, M.; Kodet, R.; Vrana, D. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients

Biomedicine and Pharmacotherapy
2016 | Journal article
EID:

2-s2.0-84982791082

Contributors: Brynychova, V.; Ehrlichova, M.; Hlavac, V.; Nemcova-Furstova, V.; Pecha, V.; Leva, J.; Trnkova, M.; Mrhalova, M.; Kodet, R.; Vrana, D. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma

BMC Cancer
2016 | Journal article
EID:

2-s2.0-84991220464

Contributors: Kunicka, T.; Prochazka, P.; Krus, I.; Bendova, P.; Protivova, M.; Susova, S.; Hlavac, V.; Liska, V.; Novak, P.; Schneiderova, M. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Role of family D ATP-binding cassette transporters (ABCD) in cancer

Biochemical Society Transactions
2015 | Journal article
EID:

2-s2.0-84947276370

Contributors: Hlaváč, V.; Souček, P.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Whole exome sequencing analysis of ABCC8 and ABCD2 genes associating with clinical course of breast carcinoma

Physiological Research
2015 | Journal article
EID:

2-s2.0-84983102643

Contributors: Souček, P.; Hlavac, V.; Elsnerova, K.; Vaclavikova, R.; Kozevnikovova, R.; Raus, K.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Non-coding polymorphisms in nucleotide binding domain 1 in ABCC1 gene associate with transcript level and survival of patients with breast cancer

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84905389396

Contributors: Kunická, T.; Václavíková, R.; Hlaváč, V.; Vrána, D.; Pecha, V.; Rauš, K.; Trnková, M.; Kubáčková, K.; Ambruš, M.; Vodičková, L. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

The role of cytochromes P450 and aldo-keto reductases in prognosis of breast carcinoma patients

Medicine (United States)
2014 | Journal article
EID:

2-s2.0-84920114444

Contributors: Hlaváč, V.; Brynychová, V.; Václavíková, R.; Ehrlichová, M.; Vrána, D.; Pecha, V.; Trnková, M.; Kodet, R.; Mrhalová, M.; Kubáčková, K. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Importance of transcript levels of caspase-2 isoforms S and L for breast carcinoma progression

Future Oncology
2013 | Journal article
EID:

2-s2.0-84874842222

Contributors: Brynychová, V.; Hlaváč, V.; Ehrlichová, M.; Václavíková, R.; Pecha, V.; Trnková, M.; Wald, M.; Mrhalová, M.; Kubáčková, K.; Pikus, T. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

The association between the expression of solute carrier transporters and the prognosis of pancreatic cancer

Cancer Chemotherapy and Pharmacology
2013 | Journal article
EID:

2-s2.0-84883489855

Contributors: Mohelnikova-Duchonova, B.; Brynychova, V.; Hlavac, V.; Kocik, M.; Oliverius, M.; Hlavsa, J.; Honsova, E.; Mazanec, J.; Kala, Z.; Melichar, B. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

The expression profile of ATP-binding cassette transporter genes in breast carcinoma

Pharmacogenomics
2013 | Journal article
EID:

2-s2.0-84875929563

Contributors: Hlaváč, V.; Brynychová, V.; Václavíková, R.; Ehrlichová, M.; Vrána, D.; Pecha, V.; Koževnikovová, R.; Trnková, M.; Gatěk, J.; Kopperová, D. et al.
Source: Self-asserted source
Viktor Hlavac via Scopus - Elsevier

Peer review (4 reviews for 3 publications/grants)

Review activity for Experimental and molecular pathology. (2)
Review activity for Experimental cell research. (1)
Review activity for World journal of surgical oncology (1)