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Physiology and pathophysiology of cerebral blood flow and, Cerebral ischemia and endogenous neuroprotection, Brain inflammation and brain-immune interaction, Interaction of brain and body after stroke (metabolism, gut microbiome, etc.), Brain imaging (Optical, MR, nuclear medicine), Systematic reviews, biostatistics, and quality control in experimental medicine
Germany

Biography

At the Charité Universitätsmedizin Berlin Ulrich Dirnagl is Professor for Clinical Neurosciences and served as Director of the Department of Experimental Neurology until 4/2022. Since 2017 he is the founding director of the QUEST Center for Responsible Research at the Berlin Institute of Health. QUEST aims at overcoming the roadblocks in translational medicine by increasing the value and impact of biomedical research through maximizing the quality, reproducibility, generalizability, and validity of research.
In preclinical as well as in clinical studies Ulrich Dirnagl’s research has revealed pathobiology which impact on the outcome after a stroke. These include deleterious as well as endogenous protective mechanisms, as interactions of the brain with other systems of the body after it has been injured. Several of these mechanism can be therapeutically targeted, clinical trials are under way. In addition, through meta-research he was able to identify opportunities for improving research practice and to obtain evidence for the impact of interventions targeted to increase the value of biomedical research.

Activities

Employment (10)

Berlin Institute of Health at Charité - Universitätsmedizin Berlin: Berlin, DE

2017 to present | Founding Director (QUEST Center for Responsible Research)
Employment
Source: Self-asserted source
Ulrich Dirnagl

Charité Universitätsmedizin Berlin NeuroCure Klinisches Forschungszentrum: Berlin, Berlin, DE

2008 to present | PI, deputy speaker
Employment
Source: Self-asserted source
Ulrich Dirnagl

Centrum für Schlaganfallforschung Berlin: Berlin, Berlin, DE

2008 to present | Director
Employment
Source: Self-asserted source
Ulrich Dirnagl

Charite Universitatsmedizin Berlin Klinik für Neurologie mit Experimenteller Neurologie: Berlin, Berlin, DE

1999 to present | Founding director until 5-2022/Group leader
Employment
Source: Self-asserted source
Ulrich Dirnagl

SPARK Berlin: Berlin, DE

2015 to 2018 | Founder (together with Craig Garner)
Employment
Source: Self-asserted source
Ulrich Dirnagl

German Center for Neurodegenerative Diseases: Berlin site, DE

2013 to 2016 | Clinical Coordinator
Employment
Source: Self-asserted source
Ulrich Dirnagl

Charite Universitatsmedizin Berlin : Berlin, Berlin, DE

2001 to 2016 | Program director (Internation Graduate Program Medical Neuroscience)
Employment
Source: Self-asserted source
Ulrich Dirnagl

Charité Universitätsmedizin Berlin: Berlin, Berlin, DE

1993 to 1999 | Founder and director (Division of Experimental Neurology)
Employment
Source: Self-asserted source
Ulrich Dirnagl

Ludwig-Maximilians-Universität München: Munich, DE

1990 to 1992 | Postdoc (Neurology)
Employment
Source: Self-asserted source
Ulrich Dirnagl

Cornell University Weill Cornell Department of Neurology: New York, NY, US

1988 to 1989 | Research fellow
Employment
Source: Self-asserted source
Ulrich Dirnagl

Education and qualifications (5)

University of Oxford: Oxford, Oxfordshire, GB

2017 to present | Visiting professor
Qualification
Source: Self-asserted source
Ulrich Dirnagl

Charite Universitatsmedizin Berlin Klinik für Neurologie mit Experimenteller Neurologie: Berlin, Berlin, DE

1999 to present | Chair and Professorship for Clinical Neuroscience
Qualification
Source: Self-asserted source
Ulrich Dirnagl

Ludwig-Maximilians-Universität München: Munich, DE

1993 to present | Habilitation (Experimental Neurology) (Neurology)
Education
Source: Self-asserted source
Ulrich Dirnagl

Ludwig-Maximilians-Universität München: Munich, DE

1988 to present | Dr.med (Neurology)
Education
Source: Self-asserted source
Ulrich Dirnagl

Ludwig-Maximilians-Universität München: Munich, DE

1979 to 1987 | MD
Education
Source: Self-asserted source
Ulrich Dirnagl

Professional activities (19)

Berlin University Press: Berlin, DE

2022 to present | Scientific advisory board member
Membership
Source: Self-asserted source
Ulrich Dirnagl

Department Klinische Forschung Uni Basel: Basel, CH

2021 to present | Scientific Advisory Board
Membership
Source: Self-asserted source
Ulrich Dirnagl

German Reproducibility Network: Berlin/Munich, DE

2020 to present | Founding member
Membership
Source: Self-asserted source
Ulrich Dirnagl

Einstein Foundation: Berlin, DE

2020 to present | Scientific Secretary, Einstein Foundation Award for Promoting Quality in Research
Service
Source: Self-asserted source
Ulrich Dirnagl

Humboldt-Universität zu Berlin: Berlin, DE

2019 to present | Member, Experten:Innenkreis Humboldt-Open
Service
Source: Self-asserted source
Ulrich Dirnagl

European Molecular Biology Organization: Heidelberg, DE

2019 to present | Member (Publication Advisory Board)
Service
Source: Self-asserted source
Ulrich Dirnagl

University of Zurich: Zurich, CH

2018 to present | Scientific Advisory Committee Member (Center for Reproducible Science)
Membership
Source: Self-asserted source
Ulrich Dirnagl

UK Reproducibility Network: Bristol, GB

2018 to present | Member (Advisory Board)
Membership
Source: Self-asserted source
Ulrich Dirnagl

Partnership for Assessment and Accreditation of Scientific Practice (PAASP): Heidelberg, DE

2016 to present | Member (Advisory Board)
Membership
Source: Self-asserted source
Ulrich Dirnagl

Fondation Leducq: Paris, FR

2015 to 2021 | Member (Scientific Advisory Committee)
Membership
Source: Self-asserted source
Ulrich Dirnagl

European Academy of Neurology: Vienna, AT

2019 | Charles Edouard Brown-Séquard Lecture
Distinction
Source: Self-asserted source
Ulrich Dirnagl

Academia Europaea: London, London, GB

2018 | Membership
Distinction
Source: Self-asserted source
Ulrich Dirnagl

University of Münster: Münster, DE

2017 | Münster Heart Lecture Award
Distinction
Source: Self-asserted source
Ulrich Dirnagl

Governing Mayor of Berlin: Berlin, DE

2016 | Berliner Wissenschaftspreis (Science Award of the City of Berlin)
Distinction
Source: Self-asserted source
Ulrich Dirnagl

American Heart Association: TX, TX, US

2016 | Thomas Willis Lecture Award
Distinction
Source: Self-asserted source
Ulrich Dirnagl

Australasian Stroke Society: Melbourne, VIC, AU

2013 | Lifetime Honorary Member
Distinction
Source: Self-asserted source
Ulrich Dirnagl

Florey Institute of Neuroscience and Mental Health: Melbourne, Victoria, AU

2008 to 2008 | Director (declined)
Invited position
Source: Self-asserted source
Ulrich Dirnagl

Deutsche Forschungsgemeinschaft: Bonn, DE

1995 | Heisenberg Fellowship
Distinction
Source: Self-asserted source
Ulrich Dirnagl

Deutsche Forschungsgemeinschaft: Bonn, DE

1993 | Gerhardt Hess Prize
Distinction
Source: Self-asserted source
Ulrich Dirnagl