Congqiang Zhang (0000-0003-1070-8806)

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Biography

A metabolic engineering scientist incorporating skills in molecular biology, protein engineering, analytical chemistry, metabolic engineering and synthetic biology, microbiology on (e.g., E. coli, S. cerevisiae and rhodotorula).
A chemical engineer incorporating skills in chemical engineering, chemistry and biochemistry, bioprocess design and optimisation (e.g., advanced fermentation).

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Agency for Science, Technology and Research: Singapore, SG

2022-04-01 to present | Principal Investigator (Singapore Institute of Food and Biotechnology Innovation)

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Congqiang Zhang

https://orcid.org/0000-0003-1070-8806

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Biography

Activities

Employment (4)

Agency for Science, Technology and Research: Singapore, SG

Agency for Science, Technology and Research: Singapore, SG

Agency for Science Technology and Research: Singapore, SG

National University of Singapore: Singapore, SG

Education and qualifications (3)

National University of Singapore: Singapore, SG

Tianjin University: Tianjin, Tianjin, CN

Tianjin University: Tianjin, Tianjin, CN

Professional activities (1)

American Institute of Chemical Engineers: New York, NY, US

Funding (1)

AME Young Individual Research Grant

Works (28)

Unravelling the aromatic symphony: redirecting bifunctional mushroom synthases towards linalool monofunctionality

Optimizing HMG-CoA Synthase Expression for Enhanced Limonene Production in Escherichia coli through Temporal Transcription Modulation Using Optogenetics

Microaerobic Fermentation Enables High-Titer Biosynthesis of the Rose Monoterpenes Geraniol and Geranyl Acetate in Escherichia coli

High-Yield Biosynthesis of trans-Nerolidol from Sugar and Glycerol

Mutagenesis of Dimer Interfacial Residues Improves the Activity and Specificity of Methyltransferase for cis-α-Irone Biosynthesis

Structural Understanding of Fungal Terpene Synthases for the Formation of Linear or Cyclic Terpene Products

Cytochrome P450 Surface Domains Prevent the β-Carotene Monohydroxylase CYP97H1 of Euglena gracilis from Acting as a Dihydroxylase

Total enzymatic synthesis of cis-α-irone from a simple carbon source

High-level de novo biosynthesis of glycosylated zeaxanthin and astaxanthin in Escherichia coli

De Novo Biosynthesis of Glycosylated Carotenoids in Escherichia Coli

Bioinformatics-aided identification, characterization and applications of mushroom linalool synthases

Bioinformatics-Aided Identification, Characterization of Fungal Linalool Synthases and Applications in Linalool biosynthesis

Metabolic Engineering Strategies for Sustainable Terpenoid Flavor and Fragrance Synthesis

Strategies for the Biosynthesis of Pharmaceuticals and Nutraceuticals in Microbes from Renewable Feedstock

Microbial astaxanthin biosynthesis: recent achievements, challenges, and commercialization outlook

Agrocybe aegerita Serves As a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi

Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli

Biosynthesis of Carotenoids and Apocarotenoids by Microorganisms and Their Industrial Potential

Multidimensional heuristic process for high-yield production of astaxanthin and fragrance molecules in Escherichia coli.

A "plug-n-play" modular metabolic system for the production of apocarotenoids.

Revalorizing lignocellulose for the production of natural pharmaceuticals and other high value bioproducts.

Multienzyme Biosynthesis of Dihydroartemisinic Acid.

In Vitro Metabolic Engineering of Amorpha-4,11-diene Biosynthesis at Enhanced Rate and Specific Yield of Production.

Efflux transporter engineering markedly improves amorphadiene production in Escherichia coli.

Experimental design-aided systematic pathway optimization of glucose uptake and deoxyxylulose phosphate pathway for improved amorphadiene production.

Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene.

Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli.

Optimization of amorphadiene synthesis in bacillus subtilis via transcriptional, translational, and media modulation.

Peer review (66 reviews for 27 publications/grants)