Personal information

Neurodegenerative Disease, Huntington's Disease, Protein misfolding, Heat Shock Factor 1
United States

Activities

Employment (3)

University of Minnesota: Minneapolis, MN, US

2017-11-01 to present | Assistant Professor (Neuroscience)
Employment
Source: Self-asserted source
Rocio Gomez-Pastor

Duke University: Durham, NC, US

2012 to 2017 | Postdoctoral Associate (Pharmacology and Cancer Biology)
Employment
Source: Self-asserted source
Rocio Gomez-Pastor

Biopolis (Spain): Valencia, ES

2010 to 2012 | Research Associate
Employment
Source: Self-asserted source
Rocio Gomez-Pastor

Education and qualifications (3)

University of Valencia: Valencia, ES

2006 to 2010 | PhD Molecular biology and Genetics (Biochemistry)
Education
Source: Self-asserted source
Rocio Gomez-Pastor

University of Valencia: Valencia, ES

2002 to 2005 | Mayor biochemistry (Biochemistry)
Education
Source: Self-asserted source
Rocio Gomez-Pastor

University of Alicante: Alicante, ES

2000-09-15 to 2002-07-04 | Minor Biology
Education
Source: Self-asserted source
Rocio Gomez-Pastor

Works (13)

Absence of hippocampal pathology persists in the Q175DN mouse model of Huntington's disease despite elevated HTT aggregation

Journal of Huntington's Disease
2025-02-03 | Journal article
Contributors: Melissa A Solem; Ross G Pelzel; Nicholas B Rozema; Taylor G Brown; Emma Reid; Rachel H Mansky; Rocio Gomez-Pastor
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Crossref

Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation

2024-10-16 | Preprint
Contributors: Melissa A Solem; Ross Pelzel; Nicholas B. Rozema; Taylor G. Brown; Emma Reid; Rachel H. Mansky; R Gomez-Pastor
Source: check_circle
Crossref

Discovery of a CK2α′-Biased ATP-Competitive Inhibitor from a High-Throughput Screen of an Allosteric-Inhibitor-Like Compound Library

ACS Chemical Neuroscience
2024-08-07 | Journal article
Contributors: Deepti Mudaliar; Rachel H. Mansky; Angel White; Grace Baudhuin; Jon Hawkinson; Henry Wong; Michael A. Walters; Rocio Gomez-Pastor
Source: check_circle
Crossref

Identification of CK2α’ selective inhibitors by the screening of an allosteric-kinase-inhibitor-like compound library

2024-01-22 | Preprint
Contributors: Deepti Mudaliar; Rachel H. Mansky; Angel White; Grace Baudhuin; Jon Hawkinson; Henry Wong; Michael A. Walters; Rocio Gomez-Pastor
Source: check_circle
Crossref

Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington’s disease

Cell Reports
2023-03 | Journal article
Contributors: Rachel H. Mansky; Erin A. Greguske; Dahyun Yu; Nicole Zarate; Taylor A. Intihar; Wei Tsai; Taylor G. Brown; Mackenzie N. Thayer; Kompal Kumar; Rocio Gomez-Pastor
Source: check_circle
Crossref

Neurochemical correlates of synapse density in a Huntington's disease mouse model

Journal of Neurochemistry
2023-01 | Journal article
Contributors: Nicole Zarate; Katherine Gundry; Dahyun Yu; Jordan Casby; Lynn E. Eberly; Gülin Öz; Rocio Gomez‐Pastor
Source: check_circle
Crossref

Protein Kinase CK2 and Its Potential Role as a Therapeutic Target in Huntington’s Disease

Biomedicines
2022-08-15 | Journal article
Contributors: Angel White; Anna McGlone; Rocio Gomez-Pastor
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Kinases and Their Potential as Therapeutic Targets in Huntington’s Disease

2022-07-01 | Preprint
Contributors: Angel White; Anna McGlone; Rocio Gomez-Pastor
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington’s Disease and Influences Striatal Synaptic Density

International Journal of Molecular Sciences
2021-12-04 | Journal article
Contributors: Nicole Zarate; Taylor A. Intihar; Dahyun Yu; Jacob Sawyer; Wei Tsai; Maha Syed; Luke Carlson; Rocio Gomez-Pastor
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Crossref
grade
Preferred source (of 2)‎

Striatal compartmentalization and clustering of different subtypes of astrocytes is altered in the zQ175 Huntington’s disease mouse model

2021-12-01 | Other
Contributors: Taylor G Brown; Mackenzie Thayer; Nicole Zarate; Rocio Gomez-Pastor
Source: check_circle
Crossref

Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington’s Disease and Influences Striatal Synaptic Density

2021-11-03 | Preprint
Contributors: Nicole Zarate; Taylor A Intihar; Dahyun Yu; Jacob Sawyer; Wei Tsai; Maha Syed; Luke Carlson; Rocio Gomez-Pastor
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

In vivo MR spectroscopy reflects synapse density in a Huntington’s disease mouse model

2021-10-28 | Preprint
Contributors: Nicole Zarate; Katherine Gundry; Dahyun Yu; Jordan Casby; Lynn E Eberly; Gülin Öz; Rocio Gomez-Pastor
Source: check_circle
Crossref

Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation

Journal of Biological Chemistry
2021-01 | Journal article
Contributors: Eileen T. Burchfiel; Anniina Vihervaara; Michael J. Guertin; Rocio Gomez-Pastor; Dennis J. Thiele
Source: check_circle
Crossref

Peer review (7 reviews for 5 publications/grants)

Review activity for European journal of pharmacology. (1)
Review activity for Nature communications (2)
Review activity for Neurobiology of disease. (2)
Review activity for Neuron. (1)
Review activity for npj aging and mechanisms of disease. (1)