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ResearcherID: L-3155-2013

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Employment (8)

University of Oxford: Oxford, Oxfordshire, GB

2007-07-01 to 2014-12-31 | Principal Fellow in Tropical Medicine (KEMRI-Wellcome Trust Research Programme, Kenya)
Employment
Source: Self-asserted source
M. J. Mackinnon

University of Cambridge: Cambridge, Cambridgeshire, GB

2006-04-01 to 2007-06-30 | Reader/Principal Research Associate (Pathology)
Employment
Source: Self-asserted source
M. J. Mackinnon

University of Edinburgh: Edinburgh, Edinburgh, GB

2001-10-01 to 2005-09-31 | Royal Society Dorothy Hodgkin Research Fellow (Institute of Cell, Animal and Population Biology)
Employment
Source: Self-asserted source
M. J. Mackinnon

CSIRO Division of Tropical Animal Production: Rockhampton, Qld, AU

1985-03-01 to 2002-12-31 | Research Officer (Animal Genetics)
Employment
Source: Self-asserted source
M. J. Mackinnon

University of Edinburgh: Edinburgh, Edinburgh, GB

2001-01-01 to 2001-09-31 | University of Edinburgh Research Fellow (Institute of Cell, Animal and Population Biology)
Employment
Source: Self-asserted source
M. J. Mackinnon

University of Edinburgh: Edinburgh, Edinburgh, GB

1998-07-16 to 2000-12-31 | Post-doctoral Researcher (Institute of Cell, Animal and Population Biology)
Employment
Source: Self-asserted source
M. J. Mackinnon

University of Edinburgh: Edinburgh, Edinburgh, GB

1994-10-01 to 1998-07-15 | Research Assistant (Institute of Cell, Animal and Population Biology)
Employment
Source: Self-asserted source
M. J. Mackinnon

Genmark Inc.: Salt Lake City, Utah, US

1993-01-01 to 1993-06-31 | Research Officer
Employment
Source: Self-asserted source
M. J. Mackinnon

Education and qualifications (4)

University of Edinburgh: Edinburgh, Edinburgh, GB

1994-10-01 to 1998-07-15 | Doctor of Philosophy (Institute of Cell, Animal and Population Biology)
Education
Source: Self-asserted source
M. J. Mackinnon

James Cook University: Townsville, QLD, AU

1986-01-01 to 1988-03-01 | Master of Science (Animal Science)
Education
Source: Self-asserted source
M. J. Mackinnon

University of New England: Armidale, NSW, AU

1984-01-01 to 1984-12-31 | Graduate Diploma of Science (Animal Science)
Education
Source: Self-asserted source
M. J. Mackinnon

University of Adelaide Roseworthy Campus: Roseworthy, SA, AU

1981-01-01 to 1983-12-30 | Diploma of Science in Agriculture
Education
Source: Self-asserted source
M. J. Mackinnon

Works (50 of 82)

Items per page:
Page 1 of 2

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)

PLOS Pathogens
2019-07-01 | Journal article
DOI: 10.1371/journal.ppat.1007870
Contributors: James Tuju; Lars Hviid; Margaret J. Mackinnon; Abdirahman I. Abdi; Henry Karanja; Jennifer N. Musyoki; George M. Warimwe; Evelyn N. Gitau; Kevin Marsh; Peter C. Bull et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

Lancet Haematol
2018-08 | Journal article
DOI: 10.1016/S2352-3026(18)30107-8
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

BMC Genomics
2018-05 | Journal article
DOI: 10.1186/s12864-018-4689-7
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Adaptation of Plasmodium falciparum to its transmission environment

Nature Ecology & Evolution
2018-02 | Journal article
DOI: 10.1038/s41559-017-0419-9
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Environmental Correlation Analysis for Genes Associated with Protection against Malaria

Mol Biol Evol
2016-05 | Journal article
DOI: 10.1093/molbev/msw004
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

The role of immunity in mosquito-induced attenuation of malaria virulence

Malaria Journal
2014 | Journal article
DOI: 10.1186/1475-2875-13-25
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

New antigens for a multicomponent blood-stage malaria vaccine

Sci Transl Med
2014-07 | Journal article
DOI: 10.1126/scitranslmed.3008705
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Mosquito transmission, growth phenotypes and the virulence of malaria parasites

Malaria Journal
2013 | Journal article
DOI: 10.1186/1475-2875-12-440
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Invited commentary on "Genes, Culture and Agriculture: an example of human niche construction" by O'Brien, M.J., and Laland, K.N

Current Anthropology
2012 | Report
Source: Self-asserted source
M. J. Mackinnon

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

BMC Genomics
2011 | Journal article
DOI: 10.1186/1471-2164-12-391
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

PLoS One
2011 | Journal article
DOI: 10.1371/journal.pone.0026005
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Establishing the extent of malaria transmission and challenges facing pre-elimination in the Republic of Djibouti

BMC Infect Dis
2011 | Journal article
DOI: 10.1186/1471-2334-11-121
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases?

Parasitology
2011 | Journal article
DOI: 10.1017/s0031182011001144
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

The selection landscape of malaria parasites

Science
2010 | Journal article
DOI: 10.1126/science.1185410
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure

Infect Immun
2009 | Journal article
DOI: 10.1128/iai.01358-08
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Chloroquine resistance before and after its withdrawal in Kenya

Malaria Journal
2009 | Journal article
DOI: 10.1186/1475-2875-8-106
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates

PLoS Pathog
2009 | Journal article
DOI: 10.1371/journal.ppat.1000644
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria

Infect Immun
2008 | Journal article
DOI: 10.1128/iai.01585-07
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Differential antibody responses to Plasmodium falciparum merozoite proteins in Malawian children with severe malaria

Journal of Infectious Diseases
2008 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Pathogen evolution in a vaccinated world

Evolution in health and disease
2008 | Book chapter
Part of ISBN: 0-19-920745-3 978-0-19-920745-9
Source: Self-asserted source
M. J. Mackinnon

Virulence evolution in malaria

Genomics of Disease
2008 | Book chapter
Source: Self-asserted source
M. J. Mackinnon

Virulence evolution in response to vaccination: the case of malaria

Vaccine
2008 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Drug resistance–virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission

Acta Tropica
2006 | Journal article
DOI: 10.1016/j.actatropica.2005.10.004
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Low multiplication rates of African Plasmodium falciparum isolates and lack of association of multiplication rate and red cell selectivity with malaria virulence

American Journal of Tropical Medicine and Hygiene
2006 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Malaria parasite virulence in mosquitoes and its implications for the introduction and efficacy of GMM malaria control programmes

Genetically modified mosquitoes for malaria control
2006 | Book chapter
Part of ISBN: 1-58706-096-5 978-1-58706-096-0
Source: Self-asserted source
M. J. Mackinnon

Increased density but not prevalence of gametocytes following drug treatment of Plasmodium falciparum

Trans R Soc Trop Med Hyg
2006-02 | Journal article
DOI: 10.1016/j.trstmh.2005.04.021
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

A genetic approach to the de novo identification of targets of strain-specific immunity in malaria parasites

Proc Natl Acad Sci U S A
2005 | Journal article
DOI: 10.1073/pnas.0405097102
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Drug resistance models in malaria

Acta Tropica
2005 | Journal article
PMID: 15894181
Source: Self-asserted source
M. J. Mackinnon

Heritability of malaria in Africa

PLoS Medicine
2005 | Journal article
Source: Self-asserted source
M. J. Mackinnon

The effects of mosquito transmission and population bottlenecking on virulence, multiplication rate and rosetting in rodent malaria

Int J Parasitol
2005 | Journal article
DOI: 10.1016/j.ijpara.2004.11.011
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Drug resistance in malaria: population biology and implications for control

Acta Tropica
2005-06 | Journal article
PMID: 15862285
Source: Self-asserted source
M. J. Mackinnon

Evolution of drug-resistance genes in Plasmodium falciparum in an area of seasonal malaria transmission in Eastern Sudan

J Infect Dis
2004 | Journal article
DOI: 10.1086/382509
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

Genetic complexity of Plasmodium falciparum in two ethnic groups in Burkina Faso with marked differences in susceptibility to malaria

American Journal of Tropical Medicine and Hygiene
2004 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Immunity promotes virulence in a malaria model

PLoS Biology
2004 | Journal article
Source: Self-asserted source
M. J. Mackinnon

The evolution of parasite virulence in response to animal and public health interventions

Infectious Disease and Host-Pathogen Evolution
2004 | Book chapter
Source: Self-asserted source
M. J. Mackinnon

Virulence in malaria: an evolutionary viewpoint

Philos Trans R Soc Lond B Biol Sci
2004 | Journal article
DOI: 10.1098/rstb.2003.1414
Source: Self-asserted source
M. J. Mackinnon
grade
Preferred source (of 2)‎

A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection agains severe malaria

Proceedings of the National Academy of Science USA
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Effects of immunity on relationships between growth rate, virulence and transmission in semi-immune hosts

Parasitology
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Imperfect vaccination: some epidemiological and evolutionary consequences

Proceedings of the Royal Society of London Series B
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Local differentiation in Plasmodium falciparum drug resistance genes in Sudan

Parasitology
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Mosquito mortality and the evolution of malaria virulence

Evolution
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Rodent malaria parasites suffer from the presence of conspecific clones in three-clone Plasmodium chabaudi infections

Parasitology
2003 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Kin selection models as evolutionary explanations of malaria

Virulence Management: The Adaptive Dynamics of Pathogen-Host Interactions
2002 | Book chapter
Source: Self-asserted source
M. J. Mackinnon

Reply to Antitoxin vaccines and pathogen virulence

Nature
2002 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Virulence in malaria parasites: host genotype by parasite genotype interactions

Infection, Genetics and Evolution
2002 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Plasmodium chabaudi: rosetting in a rodent malaria model

Exp Parasitol
2002-07 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Anti-malarial drugs clear resistant parasites from partially immune hosts

Antimicrobial Agents and Chemotherapy
2001 | Journal article
Source: Self-asserted source
M. J. Mackinnon

High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1

Journal of Infectious Diseases
2001 | Journal article
Source: Self-asserted source
M. J. Mackinnon

Novel Plasmodium falciparum clones and rising clone multipliccities are associated wuith the increase in malaria morbidity in Ghanaian children during the trasnition into the high transmission season

Parasitology
2001 | Journal article
Source: Self-asserted source
M. J. Mackinnon

The question of Plasmodium falciparum population structure

Trends in Parasitology
2001 | Journal article
Source: Self-asserted source
M. J. Mackinnon
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