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Medicinal Chemistry, Redox Active , Photo-Controlled, Reactive Oxygen Species, Cancer Biology, Radiology, PET Imaging, Diagnosis, Radiochemistry
India, United States

Biography

I am an accomplished researcher specializing in radiochemistry, medicinal chemistry and molecular imaging. My expertise includes designing and executing multi-step organic synthesis of small molecules, linear and cyclic peptides, and peptide drug conjugates. I am proficient in analytical techniques for purification and characterization of those molecules including high performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR) and mass spectrometry. I have extensive experience in generating peptides and small molecule-based theranostics using various radionuclides (18F, 64Cu, 68Ga, 177Lu, 225Ac). I possess extensive expertise in the principles and methodologies for assessing those agents both in vitro and in vivo across various tumor models. My experience spans techniques such as PET/CT and PET/MR imaging, affinity and specificity determination, conducting biodistribution studies, and analyzing images using software like Amira, Amide, and PMOD.

In pursuit of establishing my identity as a leading scientist in the area of molecular imaging and nuclear medicine, I diligently sought opportunities to propel my research forward. As a testament to my dedication, I successfully secured an Outside the Box grant from the HERA Ovarian Cancer Foundation, assuming the role of principal investigator. This esteemed award not only validates my commitment to advancing scientific inquiry but also empowers me to make meaningful contributions to the field.

Activities

Employment (2)

Johns Hopkins University: Baltimore, US

2024-10-15 to present | Research Associate (Radiology)
Employment
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Johns Hopkins University: Baltimore, MD, US

2019-10-15 to 2024-10-14 | Post Doctoral (Radiology)
Employment
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Education and qualifications (3)

Indian Institute of Science Education Research Pune: Pune, Maharashtra, IN

2014-08-01 to 2019-08-08 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Central University of Rajasthan: Ajmer, Rajasthan, IN

2012-07-15 to 2014-05-01 | M.Sc. (Chemistry)
Education
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Govt. P.G. College Karauli: Karauli, Rajasthan, IN

2009-07-01 to 2012-05-31 | B.Sc. (Biology)
Education
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Professional activities (2)

American Association For Cancer Research: Philadelphia, Pennsylvania, US

2023-02-20 to present | Associate Member (Cancer research)
Membership
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Society of Nuclear Medicine and Molecular Imaging: Reston, US

2025-01-31 to 2028-09-30 | Full Member (Radiology)
Membership
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Funding (3)

Development of EphA2-Targeted Molecular Radiotheranostics for Lung Neuroendocrine Tumors

2024-11 to 2026-10 | Grant
Neuroendocrine Tumor Research Foundation (Boston, US)
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Developing Albumin-Bound EphA2-Targeted Molecular Radiotherapeutics for Treatment of Colorectal Cancer

2024-07 to 2025-06 | Grant
Colorectal Colorectal Cancer Research Center of Excellence Pilot Award by Johns Hopkins (Baltimore, MD, US)
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Creation of an EphA2-binding Radiotherapeutic for Targeting Ovarian Cancer

2024-01 to 2024-12 | Award
HERA foundation (Boulder, Colorado, US)
Source: Self-asserted source
Dr. Ajay Kumar Sharma

Peer review (45 reviews for 17 publications/grants)

Review activity for ACS omega. (2)
Review activity for ACS pharmacology & translational science. (1)
Review activity for Antibiotics. (6)
Review activity for Biology. (2)
Review activity for Bioorganic chemistry. (5)
Review activity for Bioorganic chemistry. (5)
Review activity for Cancer imaging. (1)
Review activity for ChemBioChem. (2)
Review activity for Current oncology. (4)
Review activity for Diagnostics. (2)
Review activity for European journal of nuclear medicine and molecular imaging. (2)
Review activity for European journal of nuclear medicine and molecular imaging. (3)
Review activity for Frontiers in immunology. (1)
Review activity for Molecules. (3)
Review activity for Nature communications (2)
Review activity for PloS one. (2)
Review activity for Research. (2)