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NIH/NIDCD Staff
NIDCD Advanced Imaging Core

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Scopus Author ID: 8388065000

Keywords

Cryo-electron Tomography, Cryo-electron Microscopy, Electron Microscopy

Countries

United States

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Employment (1)

National Institutes of Health: Bethesda, MD, US

Director (NIDCD Advanced Imaging Core)
Employment
Source: Self-asserted source
Dennis C. Winkler

Works (41)

Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism

Structure
2022-04 | Journal article
DOI: 10.1016/j.str.2022.01.008
Contributors: Elif Eren; Bing Wang; Dennis C. Winkler; Norman R. Watts; Alasdair C. Steven; Paul T. Wingfield
Source: check_circle
Crossref

Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

mBio
2021-04-27 | Journal article
DOI: 10.1128/mBio.03575-20
Contributors: Michael H. C. Buch; William W. Newcomb; Dennis C. Winkler; Alasdair C. Steven; J. Bernard Heymann; Carmen San Martín; Cristina Risco Ortiz
Source: check_circle
Crossref

Cryo-electron tomography of the herpesvirus procapsid reveals interactions of the portal with the scaffold and a shift on maturation

2020-10-01 | Preprint
DOI: 10.1101/2020.09.30.320457
Contributors: Michael H. C. Buch; William W. Newcomb; Dennis C. Winkler; Alasdair C. Steven; J. Bernard Heymann
Source: check_circle
Crossref

The Mottled Capsid of the Salmonella Giant Phage SPN3US, a Likely Maturation Intermediate with a Novel Internal Shell

Viruses
2020-08-19 | Journal article
DOI: 10.3390/v12090910
Contributors: J. Bernard Heymann; Bing Wang; William W. Newcomb; Weimin Wu; Dennis C. Winkler; Naiqian Cheng; Erin R. Reilly; Ru-Ching Hsia; Julie A. Thomas; Alasdair C. Steven
Source: check_circle
Crossref
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Preferred source (of 2)‎

Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids

Proceedings of the National Academy of Sciences
2019-02-26 | Journal article
DOI: 10.1073/pnas.1813204116
Contributors: Oliver W. Bayfield; Evgeny Klimuk; Dennis C. Winkler; Emma L. Hesketh; Maria Chechik; Naiqian Cheng; Eric C. Dykeman; Leonid Minakhin; Neil A. Ranson; Konstantin Severinov et al.
Source: check_circle
Crossref

The primary enveloped virion of herpes simplex virus 1: Its role in nuclear egress

mBio
2017 | Journal article
DOI: 10.1128/mBio.00825-17
EID:

2-s2.0-85022059865
Contributors: Newcomb, W.W.; Fontana, J.; Winkler, D.C.; Cheng, N.; Bernard Heymann, J.; Stevena, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Internal proteins of the procapsid and mature capsids of herpes simplex virus 1 mapped by bubblegram imaging

Journal of Virology
2016 | Journal article
DOI: 10.1128/JVI.03224-15
EID:

2-s2.0-84977079062
Contributors: Wu, W.; Newcomb, W.W.; Cheng, N.; Aksyuk, A.; Winkler, D.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Distribution of DNA-condensing protein complexes in the adenovirus core

Nucleic Acids Research
2015 | Journal article
DOI: 10.1093/nar/gkv187
EID:

2-s2.0-84930225771
Contributors: Pérez-Berná, A.J.; Marion, S.; Chichón, F.J.; Fernández, J.J.; Winkler, D.C.; Carrascosa, J.L.; Steven, A.C.; Šiber, A.; San Martín, C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Subassemblies and asymmetry in assembly of herpes simplex virus procapsid

mBio
2015 | Journal article
DOI: 10.1128/mBio.01525-15
EID:

2-s2.0-84946607137
Contributors: Aksyuk, A.A.; Newcom, W.W.; Cheng, N.; Winkler, D.C.; Fontana, J.; Bernard Heymann, J.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress

EMBO Journal
2014 | Journal article
DOI: 10.15252/embj.201488566
EID:

2-s2.0-84906825913
Contributors: McHugh, C.A.; Fontana, J.; Nemecek, D.; Cheng, N.; Aksyuk, A.A.; Heymann, J.B.; Winkler, D.C.; Lam, A.S.; Wall, J.S.; Steven, A.C. et al.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Phage capsid-like structure of Myxococcus xanthus encapsulin, a protein shell that stores iron

Microscopy and Microanalysis
2014 | Journal article
DOI: 10.1017/S1431927614007958
EID:

2-s2.0-84927949845
Contributors: Fontana, J.; Nemecek, D.; McHugh, C.A.; Aksyuk, A.A.; Cheng, N.; Winkler, D.C.; Bernard Heymann, J.; Hoiczyk, E.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Clathrin-coated vesicles from brain have small payloads: A cryo-electron tomographic study

Journal of Structural Biology
2013 | Journal article
DOI: 10.1016/j.jsb.2013.05.006
EID:

2-s2.0-84884815779
Contributors: Heymann, J.B.; Winkler, D.C.; Yim, Y.-I.; Eisenberg, E.; Greene, L.E.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Three-dimensional structure of the toxin-delivery particle antifeeding prophage of serratia entomophila

Journal of Biological Chemistry
2013 | Journal article
DOI: 10.1074/jbc.M113.456145
EID:

2-s2.0-84883365471
Contributors: Heymann, J.B.; Bartho, J.D.; Rybakova, D.; Venugopal, H.P.; Winkler, D.C.; Sen, A.; Hurst, M.R.H.; Mitra, A.K.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Cryo-Electron Tomographic Characterization of Structural Changes in Influenza Virus at Low pH

Microscopy and Microanalysis
2012 | Journal article
DOI: 10.1017/S1431927612002395
EID:

2-s2.0-85007972631
Contributors: Winkler, D.C.; Fontana, J.; Cardone, G.; Heymann, J.B.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Cryo-electron tomography of rubella virus

Journal of Virology
2012 | Journal article
DOI: 10.1128/JVI.01390-12
EID:

2-s2.0-84869044036
Contributors: Battisti, A.J.; Yoder, J.D.; Plevka, P.; Winkler, D.C.; Prasad, V.M.; Kuhn, R.J.; Frey, T.K.; Steven, A.C.; Rossmann, M.G.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Extensive proteolysis of head and inner body proteins by a morphogenetic protease in the giant Pseudomonas aeruginosa phage φKZ

Molecular Microbiology
2012 | Journal article
DOI: 10.1111/j.1365-2958.2012.08025.x
EID:

2-s2.0-84862821249
Contributors: Thomas, J.A.; Weintraub, S.T.; Wu, W.; Winkler, D.C.; Cheng, N.; Steven, A.C.; Black, L.W.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Sample preparation induced artifacts in cryo-electron tomographs

Microscopy and Microanalysis
2012 | Journal article
DOI: 10.1017/S1431927612001298
EID:

2-s2.0-84868571653
Contributors: Plevka, P.; Battisti, A.J.; Winkler, D.C.; Tars, K.; Holdaway, H.A.; Bator, C.M.; Rossmann, M.G.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Structural changes in influenza virus at low ph characterized by cryo-electron tomography

Journal of Virology
2012 | Journal article
DOI: 10.1128/JVI.06698-11
EID:

2-s2.0-84857981961
Contributors: Fontana, J.; Cardone, G.; Heymann, J.B.; Winkler, D.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Structure and assembly of a paramyxovirus matrix protein

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
DOI: 10.1073/pnas.1210275109
EID:

2-s2.0-84865562035
Contributors: Battisti, A.J.; Meng, G.; Winkler, D.C.; McGinnes, L.W.; Plevka, P.; Steven, A.C.; Morrison, T.G.; Rossmann, M.G.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

The role of capsid maturation on adenovirus priming for sequential uncoating

Journal of Biological Chemistry
2012 | Journal article
DOI: 10.1074/jbc.M112.389957
EID:

2-s2.0-84866056104
Contributors: Pérez-Berná, A.J.; Ortega-Esteban, A.; Menéndez-Conejero, R.; Winkler, D.C.; Menéndez, M.; Steven, A.C.; Flint, S.J.; De Pablo, P.J.; San Martín, C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography

Journal of Virology
2012 | Journal article
DOI: 10.1128/JVI.01880-12
EID:

2-s2.0-84869120630
Contributors: Cardone, G.; Brecher, M.; Fontana, J.; Winkler, D.C.; Butan, C.; White, J.M.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Erratum: Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres (EMBO Reports (2011) 12 (602-606) doi: 10.1038/embor.2011.75)

EMBO Reports
2011 | Journal article
DOI: 10.1038/embor.2011.207
EID:

2-s2.0-80255127406
Contributors: Plevka, P.; Battisti, A.J.; Junjhon, J.; Winkler, D.C.; Holdaway, H.A.; Keelapang, P.; Sittisombut, N.; Kuhn, R.J.; Steven, A.C.; Rossmann, M.G.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres

EMBO Reports
2011 | Journal article
DOI: 10.1038/embor.2011.75
EID:

2-s2.0-79957981824
Contributors: Plevka, P.; Battisti, A.J.; Junjhon, J.; Winkler, D.C.; Holdaway, H.A.; Keelapang, P.; Sittisombut, N.; Kuhn, R.J.; Steven, A.C.; Rossmann, M.G.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Analysis of simian virus 40 chromatin structure by cryo-electron tomography

Microscopy and Microanalysis
2009 | Journal article
DOI: 10.1017/S1431927609096196
EID:

2-s2.0-69949176057
Contributors: Keller, P.W.; Ben-Nun Shaul, O.; Heymann, J.B..; Winkler, D.C.; Oppenheim, A.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Electron cryo-tomography demonstrates variable distributions of the viral ntpase and rna polymerase in bacteriophage φ6 Procapsids

Microscopy and Microanalysis
2009 | Journal article
DOI: 10.1017/S1431927609098730
EID:

2-s2.0-69949166214
Contributors: Nemecek, D.; Heymann, B.; Winkler, D.; Qiao, J.; Mindich, L.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Electron-tomography of a temperature-sensitive morphogenic mutant of rous sarcoma virus (RSV)

Microscopy and Microanalysis
2009 | Journal article
DOI: 10.1017/S1431927609099152
EID:

2-s2.0-69949170499
Contributors: Butan, C.; Lokhandwala, P.M.; Winkler, D.C.; Craven, R.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Capsid polymorphism of Rous sarcoma virus correlates with assembly efficiency and envelope glycoprotein content

Microscopy and Microanalysis
2008 | Journal article
DOI: 10.1017/S1431927608087904
EID:

2-s2.0-49549104860
Contributors: Butan, C.; Winkler, D.; Heymann, B.; Craven, R.; Steven, A.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Computational resources for cryo-electron tomography in Bsoft

Journal of Structural Biology
2008 | Journal article
DOI: 10.1016/j.jsb.2007.08.002
EID:

2-s2.0-40649123787
Contributors: Heymann, J.B.; Cardone, G.; Winkler, D.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Cryo-electron tomography of coated vesicles and modeling the polyhedral clathrin network

Microscopy and Microanalysis
2008 | Journal article
DOI: 10.1017/S1431927608084626
EID:

2-s2.0-49549084599
Contributors: Heymann, J.B.; Winkler, D.C.; Yim, Y.-I.; Eisenberg, E.; Greene, L.E.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Irregular and semi-regular polyhedral models for Rous sarcoma virus cores

Computational and Mathematical Methods in Medicine
2008 | Journal article
DOI: 10.1080/17486700802168106
EID:

2-s2.0-48549098071
Contributors: Heymann, J.B.; Butan, C.; Winkler, D.C.; Craven, R.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

RSV Capsid Polymorphism Correlates with Polymerization Efficiency and Envelope Glycoprotein Content: Implications that Nucleation Controls Morphogenesis

Journal of Molecular Biology
2008 | Journal article
DOI: 10.1016/j.jmb.2007.12.003
EID:

2-s2.0-39049108146
Contributors: Butan, C.; Winkler, D.C.; Heymann, J.B.; Craven, R.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Visualization of the herpes simplex virus portal in situ by cryo-electron tomography

Virology
2007 | Journal article
DOI: 10.1016/j.virol.2006.10.047
EID:

2-s2.0-34147179315
Contributors: Cardone, G.; Winkler, D.C.; Trus, B.L.; Cheng, N.; Heuser, J.E.; Newcomb, W.W.; Brown, J.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Influenza virus pleiomorphy characterized by cryoelectron tomography

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
DOI: 10.1073/pnas.0607614103
EID:

2-s2.0-34250901022
Contributors: Harris, A.; Cardone, G.; Winkler, D.C.; Heymann, J.B.; Brecher, M.; White, J.M.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Visualization of the HSV-1 portal complex in situ by cryo-electron tomography

Microscopy and Microanalysis
2006 | Journal article
DOI: 10.1017/S143192760606661X
EID:

2-s2.0-33750857434
Contributors: Cardone, G.; Winkler, D.; Trus, B.L.; Newcomb, W.W.; Brown, J.C.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Visualizing the clathrin and assembly-regulating proteins of coated vesicles by cryo-electron tomography

Microscopy and Microanalysis
2006 | Journal article
DOI: 10.1017/S1431927606067882
EID:

2-s2.0-33750878022
Contributors: Heymann, J.B.; Winkler, D.C.; Yim, Y.-I.; Eisenberg, E.; Greene, L.E.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Filaments of the Ure2p prion protein have a cross-β core structure

Journal of Structural Biology
2005 | Journal article
DOI: 10.1016/j.jsb.2005.02.007
EID:

2-s2.0-20944436593
Contributors: Baxa, U.; Cheng, N.; Winkler, D.C.; Chiu, T.K.; Davies, D.R.; Sharma, D.; Inouye, H.; Kirschner, D.A.; Wickner, R.B.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography

Science
2003 | Journal article
DOI: 10.1126/science.1090284
EID:

2-s2.0-0345306753
Contributors: Grünewald, K.; Desai, P.; Winkler, D.C.; Heymann, J.B.; Belnap, D.M.; Baumeister, W.; Steven, A.C.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Inner-shell electron excitation in the chlorosilanes

Chemical Physics Letters
1994 | Journal article
DOI: 10.1016/0009-2614(94)00047-6
EID:

2-s2.0-0009482208
Contributors: Winkler, D.C.; Moore, J.H.; Tossell, J.A.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Inner-shell electron excitation in the methylmethoxysilanes

Chemical Physics Letters
1994 | Journal article
DOI: 10.1016/0009-2614(94)00307-6
EID:

2-s2.0-0004451837
Contributors: Winkler, D.C.; Moore, J.H.; Tossell, J.A.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

Low-energy electron scattering cross sections of halofluorocarbons

The Journal of Chemical Physics
1994 | Journal article
DOI: 10.1063/1.466665
EID:

2-s2.0-0001281591
Contributors: Underwood-Lemons, T.; Winkler, D.C.; Tossell, J.A.; Moore, J.H.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier

The lowest energy unoccupied molecular orbitals of the cyclopolysilanes: experimental and theoretical studies

Chemical Physics
1994 | Journal article
DOI: 10.1016/0301-0104(94)00136-7
EID:

2-s2.0-21344493919
Contributors: Tossell, J.A.; Winkler, D.C.; Moore, J.H.
Source: Self-asserted source
Dennis C. Winkler via Scopus - Elsevier
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