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Max-Planck-Gesellschaft: Cologne, NRW, DE

Dr. (Mitochondrial Proteostasis - Langer)
Employment
Source: Self-asserted source
Hendrik Nolte

Works (50 of 61)

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Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo

eLife
2024-09-02 | Journal article
DOI: 10.7554/eLife.99263
Contributors: Juan Manuel Gomez; Hendrik Nolte; Elisabeth Vogelsang; Bipasha Dey; Michiko Takeda; Girolamo Giudice; Miriam Faxel; Theresa Haunold; Alina Cepraga; Robert P Zinzen et al.
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Crossref

CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy

Science Advances
2024-05-31 | Journal article
DOI: 10.1126/sciadv.adn2050
Contributors: Marta Zaninello; Tim Schlegel; Hendrik Nolte; Mujeeb Pirzada; Elisa Savino; Esther Barth; Ines Klein; Hauke Wüstenberg; Tesmin Uddin; Lisa Wolff et al.
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Crossref

Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver

Science
2024-04-26 | Journal article
DOI: 10.1126/science.adk1005
Contributors: Sinika Henschke; Hendrik Nolte; Judith Magoley; Tatjana Kleele; Claus Brandt; A. Christine Hausen; Claudia M. Wunderlich; Corinna A. Bauder; Philipp Aschauer; Suliana Manley et al.
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Crossref

Author Correction: A heterotypic assembly mechanism regulates CHIP E3 ligase activity

The EMBO Journal
2024-02-22 | Journal article
DOI: 10.1038/s44318-024-00042-3
Contributors: Aniruddha Das; Pankaj Thapa; Ulises Santiago; Nilesh Shanmugam; Katarzyna Banasiak; Katarzyna Dązbrowska; Hendrik Nolte; Natalia A Szulc; Rose M Gathungu; Dominik Cysewski et al.
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Crossref

Homeostatic mitophagy scales mitochondrial networks

2023-12-17 | Preprint
DOI: 10.1101/2023.12.17.572060
Contributors: R.L. Thomas; B.C. Bishop; L.M. Andre; H. Nolte; M. Graef
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Crossref

Differential regulation of the proteome and phosphosproteome along the dorso-ventral axis of the earlyDrosophilaembryo

2023-08-25 | Preprint
DOI: 10.1101/2023.08.24.554590
Contributors: Juan Manuel Gomez; Hendrik Nolte; Elisabeth Vogelsang; Bipasha Dey; Michiko Takeda; Girolamo Giudice; Miriam Faxel; Alina Cepraga; Robert Patrick Zinzen; Marcus Krüger et al.
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Crossref

SARM1 deletion delays cerebellar but not spinal cord degeneration in an enhanced mouse model of SPG7 deficiency.

Brain : a journal of neurology
2023-04-22 | Journal article
DOI: 10.1093/brain/awad136
PMID: 37086482
Contributors: Montoro-Gámez C; Nolte H; Molinié T; Evangelista G; Simon E Tröder; Barth E; Popovic M; Aleksandra Trifunovic; Zevnik B; Langer T et al.
Source: Self-asserted source
Hendrik Nolte

Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation.

Cell metabolism
2023-04-18 | Journal article
DOI: 10.1016/j.cmet.2023.03.019
PMID: 37075752
PMC: PMC10173804
Contributors: Chen W; Mehlkop O; Scharn A; Nolte H; Klemm P; Henschke S; Steuernagel L; Sotelo-Hitschfeld T; Kaya E; Wunderlich CM et al.
Source: Self-asserted source
Hendrik Nolte

The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage.

Cell reports
2023-03-31 | Journal article
DOI: 10.1016/j.celrep.2023.112332
PMID: 37002921
Contributors: Rivera-Mejías P; Álvaro Jesús Narbona-Pérez; Hasberg L; Kroczek L; Bahat A; Lawo S; Folz-Donahue K; Schumacher AL; Ahola S; Mayer FC et al.
Source: Self-asserted source
Hendrik Nolte

Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7.

Nature cell biology
2023-01-19 | Journal article
DOI: 10.1038/s41556-022-01071-y
PMID: 36658222
PMC: PMC9928583
Contributors: Soni Deshwal; Onishi M; Tatsuta T; Tim Christoph Bartsch; Cors E; Ried K; Lemke K; Nolte H; Patrick Giavalisco; Thomas Langer
Source: Self-asserted source
Hendrik Nolte

Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis.

Cancer cell international
2022-12-10 | Journal article
DOI: 10.1186/s12935-022-02800-x
PMID: 36496412
PMC: PMC9741792
Contributors: Jauch AS; Wohlfeil SA; Weller C; Dietsch B; Häfele V; Stojanovic A; Kittel M; Nolte H; Cerwenka A; Neumaier M et al.
Source: Self-asserted source
Hendrik Nolte

Inducible deletion of raptor and mTOR from adult skeletal muscle impairs muscle contractility and relaxation.

The Journal of physiology
2022-11-10 | Journal article
DOI: 10.1113/jp283686
PMID: 36255030
Contributors: Baraldo M; Zorzato S; Dondjang AHT; Alessia Geremia; Leonardo Nogara; Dumitras AG; Canato M; Lorenzo Marcucci; Nolte H; BERT BLAAUW
Source: Self-asserted source
Hendrik Nolte

NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.

Molecular metabolism
2022-11-07 | Journal article
DOI: 10.1016/j.molmet.2022.101626
PMID: 36356831
PMC: PMC9676392
Contributors: Vesting AJ; Jais A; Klemm P; Lukas Steuernagel; Wienand P; Fog-Tonnesen M; Hvid H; Schumacher AL; Kukat C; Nolte H et al.
Source: Self-asserted source
Hendrik Nolte

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

Circulation
2022-11-03 | Journal article
DOI: 10.1161/circulationaha.121.058615
PMID: 36325910
Contributors: Manta CP; Thomas Leibing; Friedrich M; Nolte H; Adrian M; Kai Schledzewski; Krzistetzko J; Kirkamm C; David Schmid C; Xi Y et al.
Source: Self-asserted source
Hendrik Nolte

OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy.

Cell metabolism
2022-09-15 | Journal article
DOI: 10.1016/j.cmet.2022.08.017
PMID: 36113464
Contributors: Sofia Ahola; Pablo Rivera Mejías; Hermans S; Chandragiri S; Giavalisco P; Nolte H; Langer T
Source: Self-asserted source
Hendrik Nolte

Regulation of mitochondrial proteostasis by the proton gradient.

The EMBO journal
2022-08-01 | Journal article
DOI: 10.15252/embj.2021110476
PMID: 35912435
PMC: PMC9379554
Contributors: Patron M; Tarasenko D; Nolte H; Lara Kroczek; Ghosh M; Ohba Y; Lasarzewski Y; Ahmadi ZA; Cabrera-Orefice A; Eyiama A et al.
Source: Self-asserted source
Hendrik Nolte

Targeting of scavenger receptors Stabilin-1 and Stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression

2022-07-01 | Preprint
DOI: 10.1101/2022.07.01.497917
Contributors: Calin-Petru Manta; Thomas Leibing; Mirco Friedrich; Hendrik Nolte; Monica Adrian; Kai Schledzewski; Jessica Krzistetzko; Christof Kirkamm; Christian David Schmid; Yannick Xi et al.
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Crossref

A heterotypic assembly mechanism regulates CHIP E3 ligase activity.

The EMBO journal
2022-06-28 | Journal article | Author
DOI: 10.15252/embj.2021109566
PMID: 35762422
PMC: PMC9340540
Contributors: Aniruddha Das; Pankaj Thapa; Ulises Santiago; Nilesh Shanmugam; Katarzyna Olek; Katarzyna Dąbrowska; Hendrik Nolte; Natalia A Szulc; Rose Gathungu; Dominik Cysewski et al.
Source: Self-asserted source
Hendrik Nolte
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Preferred source (of 2)‎

The mechanosensor Filamin A/Cheerio promotes tumourigenesis via specific interactions with components of the cell cortex.

The FEBS journal
2022-03-09 | Journal article
DOI: 10.1111/febs.16408
PMID: 35191183
Contributors: Eva Külshammer; Kilinc M; Gábor Csordás; Bresser T; Nolte H; Mirka Uhlirova
Source: Self-asserted source
Hendrik Nolte

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control.

Nature cell biology
2021-12-06 | Journal article
DOI: 10.1038/s41556-021-00798-4
PMID: 34873283
Contributors: Tim König; Nolte H; Mari J. Aaltonen; Tatsuta T; Krols M; Stroh T; Thomas Langer; Heidi McBride
Source: Self-asserted source
Hendrik Nolte

Activation of Akt-mTORC1 signalling reverts cancer-dependent muscle wasting.

Journal of cachexia, sarcopenia and muscle
2021-11-06 | Journal article
DOI: 10.1002/jcsm.12854
PMID: 34741441
PMC: PMC8818597
Contributors: Geremia A; Roberta Sartori; MARTINA BARALDO; Nogara L; Balmaceda V; Dumitras GA; Stefano Ciciliot; Scalabrin M; Nolte H; BERT BLAAUW
Source: Self-asserted source
Hendrik Nolte

Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.

Nature communications
2021-09-06 | Journal article
DOI: 10.1038/s41467-021-25570-y
PMID: 34489474
PMC: PMC8421416
Contributors: Jana Skerlova; Jens Berndtsson; Nolte H; Martin Ott; Pål Stenmark
Source: Self-asserted source
Hendrik Nolte

Depletion of <i>Numb</i> and <i>Numblike</i> in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway.

Frontiers in cell and developmental biology
2021-05-26 | Journal article
DOI: 10.3389/fcell.2021.639162
PMID: 34124033
PMC: PMC8187792
Contributors: Ianni A; Hofmann M; Kumari P; Tarighi S; Al-Tamari HM; André Görgens; Giebel B; Nolte H; Krüger M; Salwig I et al.
Source: Self-asserted source
Hendrik Nolte

ComplexFinder: A software package for the analysis of native protein complex fractionation experiments.

Biochimica et biophysica acta. Bioenergetics
2021-04-30 | Journal article
DOI: 10.1016/j.bbabio.2021.148444
PMID: 33940038
Contributors: Nolte H; Langer T
Source: Self-asserted source
Hendrik Nolte

Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.

Nature metabolism
2021-04-26 | Journal article
DOI: 10.1038/s42255-021-00385-9
PMID: 33903774
PMC: PMC8144018
Contributors: Hans-Georg Sprenger; Thomas MacVicar; Bahat A; Fiedler KU; Hermans S; Ehrentraut D; Katharina Ried; Milenkovic D; Nina Bonekamp; Nils-Göran Larsson et al.
Source: Self-asserted source
Hendrik Nolte

Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein.

Journal of molecular and cellular cardiology
2021-02-05 | Journal article
DOI: 10.1016/j.yjmcc.2021.01.010
PMID: 33549681
Contributors: Aravamudhan S; Türk C; Theresa Bock; Lena Keufgens; Nolte H; Lang F; Krishnan RK; Tim König; Hammerschmidt P; Natalie Schindler et al.
Source: Self-asserted source
Hendrik Nolte

Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling.

The Journal of biological chemistry
2021-01-23 | Journal article
DOI: 10.1016/j.jbc.2021.100335
PMID: 33497623
PMC: PMC7949116
Contributors: Eiyama A; Mari J. Aaltonen; Nolte H; Tatsuta T; Langer T
Source: Self-asserted source
Hendrik Nolte

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo.

Molecular metabolism
2020-09-19 | Journal article
DOI: 10.1016/j.molmet.2020.101085
PMID: 32956847
PMC: PMC7560164
Contributors: Melanie J. Mittenbühler; Saedler K; Nolte H; Kern L; Jun Zhou; Qian SB; Meder L; Ullrich RT; Brüning JC; Wunderlich FT
Source: Self-asserted source
Hendrik Nolte

GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.

Cell metabolism
2020-05-19 | Journal article
DOI: 10.1016/j.cmet.2020.05.001
PMID: 32433922
PMC: PMC7272126
Contributors: Timper K; Del Río-Martín A; Cremer AL; Bremser S; Alber J; Giavalisco P; Luis Varela; Heilinger C; Nolte H; Trifunovic A et al.
Source: Self-asserted source
Hendrik Nolte

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.

Nature
2019-11-06 | Journal article
DOI: 10.1038/s41586-019-1738-6
PMID: 31695197
Contributors: Thomas MacVicar; Ohba Y; Nolte H; Mayer FC; Tatsuta T; Sprenger HG; Lindner B; Zhao Y; Li J; Bruns C et al.
Source: Self-asserted source
Hendrik Nolte

Estrogen receptor α (ERα) indirectly induces transcription of human renal organic anion transporter 1 (OAT1).

Physiological reports
2019-11-01 | Journal article
DOI: 10.14814/phy2.14229
PMID: 31724834
PMC: PMC6854606
Contributors: Euteneuer AM; Seeger-Nukpezah T; Nolte H; Maja Henjakovic
Source: Self-asserted source
Hendrik Nolte

Skeletal muscle mTORC1 regulates neuromuscular junction stability.

Journal of cachexia, sarcopenia and muscle
2019-10-25 | Journal article
DOI: 10.1002/jcsm.12496
PMID: 31651100
PMC: PMC7015238
Contributors: MARTINA BARALDO; Geremia A; Marco Pirazzini; Nogara L; Solagna F; Türk C; Nolte H; Romanello V; ARAM MEGIGHIAN; Boncompagni S et al.
Source: Self-asserted source
Hendrik Nolte

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Acta neuropathologica communications
2019-10-15 | Journal article
DOI: 10.1186/s40478-019-0806-3
PMID: 31615574
PMC: PMC6794869
Contributors: Rehorst WA; Thelen MP; Nolte H; Türk C; Cirak S; Peterson JM; Wong GW; Brunhilde Wirth; Krüger M; Dominic Winter et al.
Source: Self-asserted source
Hendrik Nolte

The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons.

Cell reports
2019-06-01 | Journal article
DOI: 10.1016/j.celrep.2019.05.037
PMID: 31189104
Contributors: Ruud J; Alber J; Anna Tokarska; Engström Ruud L; Nolte H; Biglari N; Rachel N. Lippert; Lautenschlager Ä; Cieślak PE; Lukasz Szumiec et al.
Source: Self-asserted source
Hendrik Nolte

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.

Cell
2019-05-01 | Journal article
DOI: 10.1016/j.cell.2019.05.008
PMID: 31150623
Contributors: Hammerschmidt P; Ostkotte D; Nolte H; Mathias J. Gerl; Alexander Jais; Brunner HL; Sprenger HG; Awazawa M; Nicholls HT; Sarah Turpin-Nolan et al.
Source: Self-asserted source
Hendrik Nolte

Deubiquitinase USP10 regulates Notch signaling in the endothelium.

Science (New York, N.Y.)
2019-04-01 | Journal article
DOI: 10.1126/science.aat0778
PMID: 30975888
Contributors: Radiance Lim; Toshiya Sugino; Nolte H; Jorge Andrade; Zimmermann B; Shi C; Doddaballapur A; Yu Ting Ong; Kerstin Wilhelm; Fasse JWD et al.
Source: Self-asserted source
Hendrik Nolte

Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.

Cell
2018-11-01 | Journal article
DOI: 10.1016/j.cell.2018.10.015
PMID: 30445039
PMC: PMC6541012
Contributors: Brandt C; Nolte H; Henschke S; Engström Ruud L; Awazawa M; Donald Morgan; Gabel P; Sprenger HG; Hess ME; Günther S et al.
Source: Self-asserted source
Hendrik Nolte

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity.

Cell reports
2018-10-01 | Journal article
DOI: 10.1016/j.celrep.2018.09.034
PMID: 30304679
PMC: PMC6349418
Contributors: Timper K; Lars Paeger; Sánchez-Lasheras C; Luis Varela; Alexander Jais; Nolte H; Merly Vogt; Hausen AC; Heilinger C; Evers N et al.
Source: Self-asserted source
Hendrik Nolte

Instant Clue: A Software Suite for Interactive Data Visualization and Analysis.

Scientific reports
2018-08-23 | Journal article
DOI: 10.1038/s41598-018-31154-6
PMID: 30140043
PMC: PMC6107636
Source: Self-asserted source
Hendrik Nolte

Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

Cell reports
2018-05-01 | Journal article
DOI: 10.1016/j.celrep.2018.03.136
PMID: 29719249
Contributors: Wiederstein JL; Nolte H; Günther S; Piller T; MARTINA BARALDO; Kostin S; Bloch W; Natalie Schindler; Sandri M; BERT BLAAUW et al.
Source: Self-asserted source
Hendrik Nolte

Comparative Analysis of Muscle Hypertrophy Models Reveals Divergent Gene Transcription Profiles and Points to Translational Regulation of Muscle Growth through Increased mTOR Signaling.

Frontiers in physiology
2017-12-04 | Journal article
DOI: 10.3389/fphys.2017.00968
PMID: 29255421
PMC: PMC5723052
Contributors: Pereira MG; Kenneth Dyar; Leonardo Nogara; Solagna F; Marabita M; MARTINA BARALDO; Francesco Chemello; Germinario E; Romanello V; Nolte H et al.
Source: Self-asserted source
Hendrik Nolte

A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.

Nature medicine
2017-11-06 | Journal article
DOI: 10.1038/nm.4420
PMID: 29106399
Contributors: Awazawa M; Gabel P; Eva Tsaousidou; Nolte H; Krüger M; Schmitz J; Ackermann PJ; Brandt C; Janine Altmüller; Motameny S et al.
Source: Self-asserted source
Hendrik Nolte

Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1.

Proceedings of the National Academy of Sciences of the United States of America
2017-09-18 | Journal article
DOI: 10.1073/pnas.1706945114
PMID: 28923965
PMC: PMC5635888
Contributors: Jian Fang; Alessandro Ianni; Christian Smolka; Vakhrusheva O; Nolte H; Krüger M; Wietelmann A; Nicolas G. Simonet; Juan M. Adrian-Segarra; Vaquero A et al.
Source: Self-asserted source
Hendrik Nolte

Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans.

Cell reports
2017-08-01 | Journal article
DOI: 10.1016/j.celrep.2017.08.028
PMID: 28854356
PMC: PMC5583510
Contributors: Edifizi D; Nolte H; Vipin Babu; Laia Castells-Roca; Mueller MM; Susanne Brodesser; Krüger M; Björn Schumacher
Source: Self-asserted source
Hendrik Nolte

Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.

Molecular cell
2017-07-14 | Journal article
DOI: 10.1016/j.molcel.2017.06.013
PMID: 28712724
Contributors: Vukotic M; Nolte H; Tim König; Shotaro Saita; Ananjew M; Krüger M; Tatsuta T; Langer T
Source: Self-asserted source
Hendrik Nolte

Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy.

Disease models & mechanisms
2017-05-25 | Journal article
DOI: 10.1242/dmm.028910
PMID: 28546288
PMC: PMC5536905
Contributors: Lang F; Aravamudhan S; Nolte H; Türk C; Hölper S; Müller S; Günther S; BERT BLAAUW; Thomas Braun; Marcus Krueger
Source: Self-asserted source
Hendrik Nolte

PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.

Nature cell biology
2017-03-13 | Journal article
DOI: 10.1038/ncb3488
PMID: 28288130
Contributors: Shotaro Saita; Nolte H; Fiedler KU; Kashkar H; Venne AS; René Zahedi; Krüger M; Thomas Langer
Source: Self-asserted source
Hendrik Nolte

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

The Journal of cell biology
2016-12-22 | Journal article
DOI: 10.1083/jcb.201602002
PMID: 28007914
PMC: PMC5223600
Contributors: Tianliang Sun; Yang L; Kaur H; Pestel J; Mario Looso; Nolte H; Cornelius Krasel; Daniel Heil; Krishnan RK; Marie-Josée Santoni et al.
Source: Self-asserted source
Hendrik Nolte

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.

Human molecular genetics
2016-12-01 | Journal article
DOI: 10.1093/hmg/ddw352
PMID: 27794539
PMC: PMC6078604
Contributors: md shariful islam; Nolte H; Jacob W; Ziegler AB; Pütz S; Yael Grosjean; Karolina Szczepanowska; Trifunovic A; Thomas Braun; Heumann H et al.
Source: Self-asserted source
Hendrik Nolte

CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.

The EMBO journal
2016-10-20 | Journal article
DOI: 10.15252/embj.201694253
PMID: 27797820
PMC: PMC5283601
Contributors: Karolina Szczepanowska; Priyanka Maiti; Kukat A; Eduard Hofsetz; Nolte H; Senft K; Becker C; Ruzzenente B; Hornig-Do HT; Wibom R et al.
Source: Self-asserted source
Hendrik Nolte
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