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Employment (3)

Innovation Center of NanoMedicine: Kawasaki, JP

2023-04-01 to present | Senior Scientist
Employment
Source: Self-asserted source
Anjaneyulu Dirisala

Innovation Center of NanoMedicine: Kawasaki, JP

2015-04-01 to 2023-03-31 | Research Scientist
Employment
Source: Self-asserted source
Anjaneyulu Dirisala

The University of Tokyo: Tokyo, JP

2014-04-01 to 2015-03-01 | Post doctoral fellow (Department of Materials Engineering )
Employment
Source: Self-asserted source
Anjaneyulu Dirisala

Education and qualifications (5)

University of Tokyo: Tokyo, JP

2010-10-01 to 2014-03-31 | Doctor of Philosophy (Ph.D.) (Department of Bioengineering)
Education
Source: Self-asserted source
Anjaneyulu Dirisala

The University of Tokyo: Tokyo, JP

2010-04-01 to 2010-09-30 | Research Student (Department of Bioengineering )
Education
Source: Self-asserted source
Anjaneyulu Dirisala

Indian Institute of Technology Roorkee: Roorkee, IN

2008-04-01 to 2010-03-31 | Senior Research Fellow (Department of Chemistry)
Education
Source: Self-asserted source
Anjaneyulu Dirisala

University of Hyderabad: Hyderabad, IN

2005 to 2007 | Master in Technology in Medical Biotechnology (School of Life Sciences )
Education
Source: Self-asserted source
Anjaneyulu Dirisala

Andhra University: Visakhapatnam, Andhra Pradesh, IN

2003 to 2005 | Master of Science in Biochemistry (Department of Biochemistry )
Education
Source: Self-asserted source
Anjaneyulu Dirisala

Funding (4)

Preferential on-tumor expression of sticky interleukin-12 for safe local and systemic cancer immunotherapy

2023-04 to 2025-03 | Grant
Japan Science and Technology Agency (Kawasaki, JP)
URL: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23K11841/
GRANT_NUMBER: 23K11841
Source: Self-asserted source
Anjaneyulu Dirisala

On the mechanism of minimizing off-targeting and maximizing retargeting of mRNA vaccines from the liver to spleen

2022-09 to 2023-03 | Grant
Japan Agency for Medical Research and Development (Tokyo, JP)
URL: https://www.amed.go.jp/en/news/program/2001C_00012.html
Source: Self-asserted source
Anjaneyulu Dirisala

Ligand-free hepatocyte-targeting of nanomedicines by selective stealth coating of liver reticuloendothelial system scavenger cells

2021-04 to 2023-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (Tokyo, JP)
URL: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21K18062/
GRANT_NUMBER: 21K18062
Source: Self-asserted source
Anjaneyulu Dirisala

Reticuloendothelial system blockade by PEG-oligo(amino acid) block copolymers: A strategy for functional tuning of nanomedicine pharmacokinetics

2018-04 to 2021-03 | Grant
Ministry of Education, Culture, Sports, Science and Technology (Tokyo, JP)
URL: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-18K18393/
GRANT_NUMBER: 18K18393
Source: Self-asserted source
Anjaneyulu Dirisala

Works (41)

Adeno-Associated Virus Self-Assembled with Tannic Acid and Phenylboronic Acid Polymers to Evade Neutralizing Antibodies and Reduce Adverse Events

ACS Nano
2025-03-04 | Journal article
DOI: 10.1021/acsnano.4c11085
Contributors: Yuto Honda; Shuhei Nagao; Hiroaki Kinoh; Xueying Liu; Nozomi Matsudaira; Anjaneyulu Dirisala; Shoko Nitta-Matsutomo; Takahiro Nomoto; Hiromi Hayashita-Kinoh; Yutaka Miura et al.
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Facile Generation of Heterotelechelic Poly(2‐Oxazoline)s Towards Accelerated Exploration of Poly(2‐Oxazoline)‐Based Nanomedicine

Angewandte Chemie
2024-07 | Journal article
DOI: 10.1002/ange.202404972
Contributors: Joachim F. R. Van Guyse; Saed Abbasi; Kazuko Toh; Zlata Nagorna; Junjie Li; Anjaneyulu Dirisala; Sabina Quader; Satoshi Uchida; Kazunori Kataoka
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Facile generation of heterotelechelic poly(2‐oxazoline)s towards accelerated exploration of poly(2‐oxazoline)‐based nanomedicine

Angewandte Chemie International Edition
2024-04-23 | Journal article
DOI: 10.1002/anie.202404972
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Contributors: Joachim F. R. Van Guyse; Saed Abbasi; Kazuko Toh; Zlata Nagorna; Junjie Li; Anjaneyulu Dirisala; Sabina Quader; Satoshi Uchida; Kazunori Kataoka
Source: Self-asserted source
Anjaneyulu Dirisala
grade
Preferred source (of 2)‎

Oligosarcosine Conjugation of Arginine-Rich Peptides Improves the Intracellular Delivery of Peptide/pDNA Complexes

ACS Biomaterials Science & Engineering
2024-02-12 | Journal article
DOI: 10.1021/acsbiomaterials.3c01542
Contributors: Hidetomo Yokoo; Anjaneyulu Dirisala; Satoshi Uchida; Makoto Oba
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Nanoarchitectonics of mesoporous carbon spheres by tuning the weight ratio of PEG-PCL block copolymer as template and phenol as carbon source towards supercapacitor applications

Journal of Materials Science: Materials in Electronics
2024-01 | Journal article
DOI: 10.1007/s10854-023-11872-y
Contributors: M. Murugan; G. Dineshkumar; Anjaneyulu Dirisala; P. Jegadeesan; M. Ganesan; S. Amirthapandian; M. Sivanantham
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Acidic pH-Triggered Release of Doxorubicin from Ligand-Decorated Polymeric Micelles Potentiates Efficacy against Cancer Cells

ACS Applied Nano Materials
2023-10-27 | Journal article
DOI: 10.1021/acsanm.3c03481
Contributors: Sayoni Maitra Roy; Sourav Barman; Purvi Kishore; Bhaskar Chatterjee; Pousali Bag; Tapas Ghatak; Arnab Basu; Surya K. Ghosh; Anjaneyulu Dirisala; Ankan Kumar Sarkar et al.
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pH-responsive polyzwitterion covered nanocarriers for DNA delivery

Journal of Controlled Release
2023-08 | Journal article
DOI: 10.1016/j.jconrel.2023.07.038
Part of ISSN: 0168-3659
Contributors: Xin Shen; Anjaneyulu Dirisala; Masahiro Toyoda; Yao Xiao; Haochen Guo; Yuto Honda; Takahiro Nomoto; Hiroyasu Takemoto; Yutaka Miura; Nobuhiro Nishiyama
Source: Self-asserted source
Anjaneyulu Dirisala

Editorial: Delivery systems in biologics-based therapeutics

Frontiers in Bioengineering and Biotechnology
2023-08-18 | Journal article
DOI: 10.3389/fbioe.2023.1274210
Part of ISSN: 2296-4185
Contributors: Anjaneyulu Dirisala; Junjie Li; Daniel Gonzalez-Carter; Zheng Wang
Source: Self-asserted source
Anjaneyulu Dirisala

Multiple Carbon Morphologies Derived from Polyion Complex-Based Double Hydrophilic Block Copolymers as Templates and Phenol as a Carbon Precursor

Langmuir
2023-08-08 | Journal article
DOI: 10.1021/acs.langmuir.2c03364
Contributors: M. Sivanantham; Ramsankar Senthamaraikannan; Anjaneyulu Dirisala; Chanchal Ghosh; Debes Ray; Chetna Tewari; Ramesh Padamati; Soumyadip Choudhury; Yong Chae Jung
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Stealth and pseudo-stealth nanocarriers

Advanced Drug Delivery Reviews
2023-07 | Journal article
DOI: 10.1016/j.addr.2023.114895
Part of ISSN: 0169-409X
Contributors: Panyue Wen; Wendong Ke; Anjaneyulu Dirisala; Kazuko Toh; Masaru Tanaka; Li Junjie
Source: Self-asserted source
Anjaneyulu Dirisala

Deciphering the Structural and Functional Properties of ABC-F ATPases

Infectious Diseases Diagnosis & Treatment
2023-07-31 | Journal article
DOI: 10.29011/2577-1515.100225
Part of ISSN: 2577-1515
Source: Self-asserted source
Anjaneyulu Dirisala
grade
Preferred source (of 2)‎

Overcoming the barriers of nuclear-targeted drug delivery using nanomedicine-based strategies for enhanced anticancer therapy

Journal of Drug Delivery Science and Technology
2023-05 | Journal article
DOI: 10.1016/j.jddst.2023.104408
Contributors: Sayoni Maitra Roy; Vrinda Garg; Sushmitha Pedugu Sivaraman; Sourav Barman; Chitrita Ghosh; Pousali Bag; Palanivelmurugan Mohanasundaram; Partha Sona Maji; Arnab Basu; Anjaneyulu Dirisala et al.
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Curcumin and Colistin are Synergistic in Inhibiting the Growth and Biofilm Formation of Pseudomonas aeruginosa Isolated from Environmental Sample

Infectious Diseases Diagnosis & Treatment
2023-05-25 | Journal article
DOI: 10.29011/2577-1515.100218
Part of ISSN: 2577-1515
Source: Self-asserted source
Anjaneyulu Dirisala

Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery

Advanced Healthcare Materials
2022 | Journal article
DOI: 10.1002/ADHM.202102016
WOSUID: WOS:000733562100001
Contributors: Yoshinaga, Naoto; Uchida, Satoshi; Dirisala, Anjaneyulu; Naito, Mitsuru; Koji, Kyoko; Osada, Kensuke; Cabral, Horacio; Kataoka, Kazunori
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Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency

Macromolecular Rapid Communications
2022 | Journal article
DOI: 10.1002/MARC.202100754
WOSUID: WOS:000770483200001
Contributors: Dirisala, Anjaneyulu; Uchida, Satoshi; Li, Junjie; Van Guyse, Joachim F. R.; Hayashi, Kotaro; Vummaleti, Sai V. C.; Kaur, Sarandeep; Mochida, Yuki; Fukushima, Shigeto; Kataoka, Kazunori
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Nanocarriers escaping from hyperacidified endo/lysosomes in cancer cells allow tumor-targeted intracellular delivery of antibodies to therapeutically inhibit c-MYC

Biomaterials
2022-09 | Journal article
DOI: 10.1016/j.biomaterials.2022.121748
Contributors: Pengwen Chen; Wenqian Yang; Taehun Hong; Takuya Miyazaki; Anjaneyulu Dirisala; Kazunori Kataoka; Horacio Cabral
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Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain

Journal of Controlled Release
2021 | Journal article
DOI: 10.1016/J.JCONREL.2021.02.026
WOSUID: WOS:000646445800005
Contributors: Abbasi, Saed; Uchida, Satoshi; Toh, Kazuko; Tockary, Theofilus A.; Dirisala, Anjaneyulu; Hayashi, Kotaro; Fukushima, Shigeto; Kataoka, Kazunori
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Enzymatically Transformable Polymersome-Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer

Advanced Materials
2021 | Journal article
DOI: 10.1002/ADMA.202105254
WOSUID: WOS:000704910000001
Contributors: Li, Junjie; Ge, Zhishen; Toh, Kazuko; Liu, Xueying; Dirisala, Anjaneyulu; Ke, Wendong; Wen, Panyue; Zhou, Hang; Wang, Zheng; Xiao, Shiyan et al.
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mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency

Journal of Controlled Release
2021 | Journal article
DOI: 10.1016/J.JCONREL.2020.12.033
WOSUID: WOS:000626459100023
Contributors: Yoshinaga, Naoto; Uchida, Satoshi; Dirisala, Anjaneyulu; Naito, Mitsuru; Osada, Kensuke; Cabral, Horacio; Kataoka, Kazunori
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Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain

ACS Nano
2020 | Journal article
DOI: 10.1021/ACSNANO.9B09991
WOSUID: WOS:000543744100032
Contributors: Xie, Jinbing; Gonzalez-Carter, Daniel; Tockary, Theofilus A.; Nakamura, Noriko; Xue, Yonger; Nakakido, Makoto; Akiba, Hiroki; Dirisala, Anjaneyulu; Liu, Xueying; Toh, Kazuko et al.
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Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium

Proceedings of the National Academy of Sciences
2020-08-11 | Journal article
DOI: 10.1073/pnas.2002016117
Contributors: Daniel Gonzalez-Carter; Xueying Liu; Theofilus A. Tockary; Anjaneyulu Dirisala; Kazuko Toh; Yasutaka Anraku; Kazunori Kataoka
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Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

Science Advances
2020-06-26 | Journal article
DOI: 10.1126/sciadv.abb8133
Contributors: Anjaneyulu Dirisala; Satoshi Uchida; Kazuko Toh; Junjie Li; Shigehito Osawa; Theofilus A. Tockary; Xueying Liu; Saed Abbasi; Kotaro Hayashi; Yuki Mochida et al.
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Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability

Journal of Drug Targeting
2019 | Journal article
DOI: 10.1080/1061186X.2018.1550646
WOSUID: WOS:000468468900018
Contributors: Dirisala, Anjaneyulu; Uchida, Satoshi; Tockary, Theofilus A.; Yoshinaga, Naoto; Li, Junjie; Osawa, Shigehito; Gorantla, Lahari; Fukushima, Shigeto; Osada, Kensuke; Kataoka, Kazunori
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Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer

ACS Nano
2019 | Journal article
DOI: 10.1021/ACSNANO.9B04676
WOSUID: WOS:000500650000047
Contributors: Tockary, Theofilus A.; Foo, Wanling; Dirisala, Anjaneyulu; Chen, Qixian; Uchida, Satoshi; Osawa, Shigehito; Mochida, Yuki; Liu, Xueying; Kinoh, Hiroaki; Cabral, Horacio et al.
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Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(L-lysine) block copolymers as systemic gene delivery carrier

Biomaterials
2017 | Journal article
DOI: 10.1016/J.BIOMATERIALS.2017.02.012
WOSUID: WOS:000397548300004
Contributors: Takeda, Kaori M.; Yamasaki, Yuichi; Dirisala, Anjaneyulu; Ikeda, Sorato; Tockary, Theofilus A.; Toh, Kazuko; Osada, Kensuke; Kataoka, Kazunori
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Poly(ethylene glycol) Crowding as Critical Factor To Determine pDNA Packaging Scheme into Polyplex Micelles for Enhanced Gene Expression

Biomacromolecules
2017 | Journal article
DOI: 10.1021/ACS.BIOMAC.6B01247
WOSUID: WOS:000391781100003
Contributors: Takeda, Kaori M.; Osada, Kensuke; Tockary, Theofilus A.; Dirisala, Anjaneyulu; Chen, Qixian; Kataoka, Kazunori
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Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting

Biomaterials
2017 | Journal article
DOI: 10.1016/J.BIOMATERIALS.2016.10.042
WOSUID: WOS:000389396300021
Contributors: Chen, Qixian; Osada, Kensuke; Ge, Zhishen; Uchida, Satoshi; Tockary, Theofilus A.; Dirisala, Anjaneyulu; Matsui, Akitsugu; Toh, Kazuko; Takeda, Kaori M.; Liu, Xueying et al.
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Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross-Linked Nanostructures

Angewandte Chemie International Edition
2017 | Journal article
DOI: 10.1002/ANIE.201702624
WOSUID: WOS:000406385200068
Contributors: Klinker, Kristina; Schaefer, Olga; Huesmann, David; Bauer, Tobias; Capeloa, Leon; Braun, Lydia; Stergiou, Natascha; Schinnerer, Meike; Dirisala, Anjaneyulu; Miyata, Kanjiro et al.
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Therapeutic Vesicular Nanoreactors with Tumor-Specific Activation and Self-Destruction for Synergistic Tumor Ablation

Angewandte Chemie International Edition
2017 | Journal article
DOI: 10.1002/ANIE.201706964
WOSUID: WOS:000413896400018
Contributors: Li, Junjie; Dirisala, Anjaneyulu; Ge, Zhishen; Wang, Yuheng; Yin, Wei; Ke, Wendong; Toh, Kazuko; Xie, Jinbing; Matsumoto, Yu; Anraku, Yasutaka et al.
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A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments

Biomacromolecules
2016 | Journal article
DOI: 10.1021/ACS.BIOMAC.6B00239
WOSUID: WOS:000375886500028
Contributors: Florinas, Stelios; Liu, Marc; Fleming, Ryan; Van Vlerken-Ysla, Lilian; Ayriss, Joanne; Gilbreth, Ryan; Dimasi, Nazzareno; Gao, Changshou; Wu, Herren; Xu, Ze-Qi et al.
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Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity

Biomaterials
2016 | Journal article
DOI: 10.1016/J.BIOMATERIALS.2016.02.027
WOSUID: WOS:000374618100006
Contributors: Perche, F.; Yi, Y.; Hespel, L.; Mi, P.; Dirisala, A.; Cabral, H.; Miyata, K.; Kataoka, K.
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Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection

Biomacromolecules
2016 | Journal article
DOI: 10.1021/ACS.BIOMAC.5B01456
WOSUID: WOS:000368047800038
Contributors: Osawa, Shigehito; Osada, Kensuke; Hiki, Shigehiro; Dirisala, Anjaneyulu; Ishii, Takehiko; Kataoka, Kazunori
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Rod-to-Globule Transition of pDNA/PEG-Poly(L-Lysine) Polyplex Micelles Induced by a Collapsed Balance Between DNA Rigidity and PEG Crowdedness

Small
2016 | Journal article
DOI: 10.1002/SMLL.201501815
WOSUID: WOS:000372008600011
Contributors: Tockary, Theofilus A.; Osada, Kensuke; Motoda, Yusuke; Hiki, Shigehiro; Chen, Qixian; Takeda, Kaori M.; Dirisala, Anjaneyulu; Osawa, Shigehito; Kataoka, Kazunori
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Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer

Current Alzheimer Research
2016-11-08 | Journal article
DOI: 10.2174/1567205013666161108110031
Part of ISSN: 1567-2050
Source: Self-asserted source
Anjaneyulu Dirisala

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle

Soft Matter
2015 | Journal article
DOI: 10.1039/C4SM02850C
WOSUID: WOS:000351711800001
Contributors: Chen, Qixian; Osada, Kensuke; Pennisi, Matthew; Uchida, Satoshi; Tockary, Theofilus A.; Dirisala, Anjaneyulu; Li, Yanmin; Takeda, Kaori M.; Oniyanagi, Satoshi; Itaka, Keiji et al.
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Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery

Journal of Controlled Release
2015 | Journal article
DOI: 10.1016/J.JCONREL.2015.04.024
WOSUID: WOS:000355674300009
Contributors: Li, Junjie; Chen, Qixian; Zha, Zengshi; Li, Hui; Toh, Kazuko; Dirisala, Anjaneyulu; Matsumoto, Yu; Osada, Kensuke; Kataoka, Kazunori; Ge, Zhishen
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Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression

Biomacromolecules
2015 | Journal article
DOI: 10.1021/ACS.BIOMAC.5B00491
WOSUID: WOS:000361341700012
Contributors: Li, Yanmin; Osada, Kensuke; Chen, Qixian; Tockary, Theofilus A.; Dirisala, Anjaneyulu; Takeda, Kaori M.; Uchida, Satoshi; Nagata, Kazuya; Itaka, Keiji; Kataoka, Kazunori
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Design of poly(oxazoline) based triblock copolymer for polyplex micelles with core protective parisade

Abstracts of Papers of the American Chemical Society
2014 | Journal article
WOSUID: WOS:000349167405347
Contributors: Osawa, Shigehito; Osada, Kensuke; Hiki, Shigehiro; Dirisala, Anjaneyulu; Takemoto, Hiroyasu; Ishii, Takehiko; Kataoka, Kazunori
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Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors

Biomaterials
2014 | Journal article
DOI: 10.1016/J.BIOMATERIALS.2014.03.037
WOSUID: WOS:000336471300009
Contributors: Dirisala, Anjaneyulu; Osada, Kensuke; Chen, Qixian; Tockary, Theofilus A.; Machitani, Kaori; Osawa, Shigehito; Liu, Xueying; Ishii, Takehiko; Miyata, Kanjiro; Oba, Makoto et al.
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Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

Biomaterials
2014 | Journal article
DOI: 10.1016/J.BIOMATERIALS.2013.12.086
WOSUID: WOS:000332188400027
Contributors: Ge, Zhishen; Chen, Qixian; Osada, Kensuke; Liu, Xueying; Tockary, Theofilus A.; Uchida, Satoshi; Dirisala, Anjaneyulu; Ishii, Takehiko; Nomoto, Takahiro; Toh, Kazuko et al.
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Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers

Macromolecules
2013 | Journal article
DOI: 10.1021/MA401093Z
WOSUID: WOS:000323811100023
Contributors: Tockary, Theofilus A.; Osada, Kensuke; Chen, Qixian; Machitani, Kaori; Dirisala, Anjaneyulu; Uchida, Satoshi; Nomoto, Takahiro; Toh, Kazuko; Matsumoto, Yu; Itaka, Keiji et al.
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Peer review (12 reviews for 5 publications/grants)

Review activity for ACS omega. (2)
Review activity for European journal of pharmaceutics and biopharmaceutics. (1)
Review activity for Journal of controlled release. (7)
Review activity for Journal of drug delivery science and technology. (1)
Review activity for Journal of molecular liquids. (1)
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